{"id":5163,"date":"2024-01-16T12:29:30","date_gmt":"2024-01-16T12:29:30","guid":{"rendered":"https:\/\/farlong.com\/?p=5163"},"modified":"2024-01-27T10:12:46","modified_gmt":"2024-01-27T10:12:46","slug":"clinical-benefits-and-pharmacology-of-scutellarin-a-comprehensive-review","status":"publish","type":"post","link":"https:\/\/directcm.com\/ja\/clinical-benefits-and-pharmacology-of-scutellarin-a-comprehensive-review\/","title":{"rendered":"\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306e\u81e8\u5e8a\u4e0a\u306e\u5229\u70b9\u3068\u85ac\u7406\u5b66: \u5305\u62ec\u7684\u306a\u30ec\u30d3\u30e5\u30fc"},"content":{"rendered":"<div id=\"preview-section-abstract\">\n<div id=\"abstracts\" class=\"Abstracts u-font-serif text-s\">\n<div id=\"ab0005\" class=\"abstract author\" lang=\"en\">\n<h2 class=\"section-title u-h4 u-margin-l-top u-margin-xs-bottom\">\u62bd\u8c61\u7684\u306a<\/h2>\n<div id=\"as0005\">\n<p id=\"sp0025\">\u8133\u5352\u4e2d\u3068\u5fc3\u7b4b\u6897\u585e\u306f\u3001\u4e16\u754c\u3067\u6700\u3082\u4e00\u822c\u7684\u306a\u6b7b\u4ea1\u304a\u3088\u3073\u969c\u5bb3\u306e\u539f\u56e0\u306e 1 \u3064\u3067\u3059\u3002\u3053\u308c\u3089\u306e\u75be\u60a3\u306e\u6839\u5e95\u306b\u3042\u308b\u865a\u8840\u6027\u640d\u50b7\u306f\u8907\u96d1\u3067\u3042\u308a\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u3001\u8840\u7ba1\u8abf\u7bc0\u3001\u8840\u884c\u529b\u5b66\u3001\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3001\u708e\u75c7\u3001\u8840\u5c0f\u677f\u6d3b\u6027\u5316\u3001\u7d44\u7e54\u4fee\u5fa9\u306a\u3069\u3001\u72b6\u6cc1\u304a\u3088\u3073\u6642\u9593\u306b\u4f9d\u5b58\u3057\u3066\u8d77\u3053\u308b\u591a\u304f\u306e\u751f\u7269\u5b66\u7684\u6a5f\u80fd\u9593\u306e\u8907\u96d1\u306a\u76f8\u4e92\u4f5c\u7528\u304c\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u73fe\u5728\u9078\u629e\u3055\u308c\u3066\u3044\u308b\u85ac\u7269\u7642\u6cd5\u306f\u3001\u865a\u8840\u7d44\u7e54\u306b\u9069\u6642\u306b\u8840\u6db2\u3092\u518d\u4f9b\u7d66\u3059\u308b\u3053\u3068\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u518d\u704c\u6d41\u306f\u3001\u865a\u8840\/\u518d\u704c\u6d41\u50b7\u5bb3\u3068\u3057\u3066\u77e5\u3089\u308c\u308b\u30d7\u30ed\u30bb\u30b9\u3092\u901a\u3058\u3066\u7d44\u7e54\u306b\u3055\u3089\u306a\u308b\u5bb3\u3092\u3082\u305f\u3089\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u795e\u7d4c\u304a\u3088\u3073\u5fc3\u8840\u7ba1\u306e\u4fdd\u8b77\u3092\u63d0\u4f9b\u3057\u3001\u6a19\u7684\u3092\u6a19\u7684\u306b\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u518d\u704c\u6d41\u3092\u88dc\u5b8c\u3059\u308b\u65b0\u85ac\u304c\u958b\u767a\u3055\u308c\u307e\u3059\u3002\u00a0<a class=\"topic-link\" title=\"ScienceDirect \u306e AI \u751f\u6210\u30c8\u30d4\u30c3\u30af \u30da\u30fc\u30b8\u304b\u3089\u8907\u6570\u306e\u7570\u5e38\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u5b66\u3073\u307e\u3059\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/multiple-malformation-syndrome\">\u8907\u6570\u306e\u7570\u5e38<\/a>\u00a0\u3067\u00a0<a class=\"topic-link\" title=\"ScienceDirect \u306e AI \u751f\u6210\u30c8\u30d4\u30c3\u30af \u30da\u30fc\u30b8\u304b\u3089\u865a\u8840\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u5b66\u3073\u307e\u3057\u3087\u3046\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/ischemia\">\u865a\u8840<\/a>\u00a0\u307e\u3059\u307e\u3059\u6ce8\u76ee\u3092\u96c6\u3081\u3066\u3044\u307e\u3059\u3002\u00a0<a class=\"topic-link\" title=\"ScienceDirect \u306e AI \u751f\u6210\u30c8\u30d4\u30c3\u30af \u30da\u30fc\u30b8\u304b\u3089\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u5b66\u3073\u307e\u3057\u3087\u3046\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/scutellarin\">\u30b9\u30af\u30c6\u30e9\u30ea\u30f3<\/a>\u00a0\u30cf\u30fc\u30d6\u3067\u3059\u00a0<a class=\"topic-link\" title=\"ScienceDirect \u306e AI \u751f\u6210\u30c8\u30d4\u30c3\u30af \u30da\u30fc\u30b8\u304b\u3089\u30d5\u30e9\u30dc\u30ce\u30a4\u30c9\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u5b66\u3073\u307e\u3057\u3087\u3046\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/flavonoid\">\u30d5\u30e9\u30dc\u30ce\u30a4\u30c9<\/a>\u00a0<a class=\"topic-link\" title=\"ScienceDirect \u306e AI \u751f\u6210\u30c8\u30d4\u30c3\u30af \u30da\u30fc\u30b8\u304b\u3089\u30b0\u30eb\u30af\u30ed\u30cb\u30c9\u306b\u3064\u3044\u3066\u3055\u3089\u306b\u8a73\u3057\u304f\u5b66\u3076\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/glucuronide\">\u30b0\u30eb\u30af\u30ed\u30cb\u30c9<\/a>\u00a0\u8907\u6570\u306e\u00a0<a class=\"topic-link\" title=\"ScienceDirect \u306e AI \u751f\u6210\u30c8\u30d4\u30c3\u30af \u30da\u30fc\u30b8\u304b\u3089\u85ac\u7406\u5b66\u7684\u6d3b\u52d5\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u5b66\u3073\u307e\u3057\u3087\u3046\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/pharmacological-activity\">\u85ac\u7406\u6d3b\u6027<\/a>\u3002\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306f\u3001\u6297\u9178\u5316\u3001\u6297\u708e\u75c7\u3001\u8840\u7ba1\u5f1b\u7de9\u3001\u6297\u8840\u5c0f\u677f\u3001\u6297\u51dd\u56fa\u3001\u5fc3\u7b4b\u4fdd\u8b77\u306a\u3069\u306e\u8907\u6570\u306e\u6709\u76ca\u306a\u52b9\u679c\u306b\u3088\u308a\u3001\u8133\u5352\u4e2d\u3001\u5fc3\u7b4b\u6897\u585e\u3001\u304a\u3088\u3073\u8133\u5352\u4e2d\u3092\u6cbb\u7642\u3059\u308b\u305f\u3081\u306b\u81e8\u5e8a\u7684\u306b\u4f7f\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u00a0<a class=\"topic-link\" title=\"ScienceDirect \u306e AI \u751f\u6210\u30c8\u30d4\u30c3\u30af \u30da\u30fc\u30b8\u304b\u3089\u7cd6\u5c3f\u75c5\u5408\u4f75\u75c7\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u5b66\u3073\u307e\u3057\u3087\u3046\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/diabetic-complication\">\u7cd6\u5c3f\u75c5\u5408\u4f75\u75c7<\/a>\u3002\u904e\u53bb 30 \u5e74\u306b\u308f\u305f\u308a\u3001\u81e8\u5e8a\u7814\u7a76\u304a\u3088\u3073\u85ac\u7406\u5b66\u7684\u7814\u7a76\u306b\u3088\u308a\u3001\u3053\u308c\u3089\u306e\u6cbb\u7642\u52b9\u679c\u3092\u8a3c\u660e\u3059\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u6cbb\u7642\u52b9\u679c\u306b\u95a2\u3059\u308b\u91cd\u8981\u306a\u6d1e\u5bdf\u3082\u63d0\u4f9b\u3059\u308b\u4e00\u9023\u306e\u8a3c\u62e0\u304c\u84c4\u7a4d\u3055\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u00a0<a class=\"topic-link\" title=\"ScienceDirect \u306e AI \u751f\u6210\u306e\u30c8\u30d4\u30c3\u30af \u30da\u30fc\u30b8\u304b\u3089\u85ac\u7269\u52d5\u614b\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u5b66\u3073\u307e\u3057\u3087\u3046\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/pharmacokinetics\">\u85ac\u7269\u52d5\u614b\u5b66<\/a>\u00a0\u30d2\u30c8\u304a\u3088\u3073\u52d5\u7269\u30e2\u30c7\u30eb\u306b\u304a\u3051\u308b\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306e\u6319\u52d5\u3001\u6cbb\u7642\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3001\u4f5c\u7528\u6a5f\u5e8f\u3002\u533b\u85ac\u54c1\u306e\u4fee\u98fe\u3068\u65b0\u3057\u3044\u85ac\u7269\u9001\u9054\u65b9\u6cd5\u306b\u3088\u308a\u3001\u30d0\u30a4\u30aa\u30a2\u30d9\u30a4\u30e9\u30d3\u30ea\u30c6\u30a3\u3001\u6709\u52b9\u6027\u3001\u5b89\u5168\u6027\u304c\u5411\u4e0a\u3057\u305f\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306e\u65b0\u3057\u3044\u8a98\u5c0e\u4f53\u3068\u88fd\u5264\u306e\u958b\u767a\u304c\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u3053\u3067\u306f\u3001\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306b\u95a2\u3059\u308b\u73fe\u5728\u306e\u6587\u732e\u3092\u30ec\u30d3\u30e5\u30fc\u3057\u3066\u3001\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306e\u85ac\u7406\u5b66\u7684\u6d3b\u6027\u3001\u4f5c\u7528\u6a5f\u5e8f\u3001\u6bd2\u6027\u3001\u304a\u3088\u3073\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306e\u6cbb\u7642\u4e0a\u306e\u53ef\u80fd\u6027\u3092\u5305\u62ec\u7684\u306b\u7406\u89e3\u3057\u307e\u3059\u3002\u00a0<a class=\"topic-link\" title=\"ScienceDirect \u306e AI \u751f\u6210\u30c8\u30d4\u30c3\u30af \u30da\u30fc\u30b8\u304b\u3089\u865a\u8840\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u5b66\u3073\u307e\u3057\u3087\u3046\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/ischemia\">\u865a\u8840<\/a>,\u00a0<a class=\"topic-link\" title=\"ScienceDirect \u306e AI \u751f\u6210\u30c8\u30d4\u30c3\u30af \u30da\u30fc\u30b8\u304b\u3089\u7cd6\u5c3f\u75c5\u5408\u4f75\u75c7\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u5b66\u3073\u307e\u3057\u3087\u3046\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/diabetic-complication\">\u7cd6\u5c3f\u75c5\u5408\u4f75\u75c7<\/a>\u3001\u305d\u306e\u4ed6\u306e\u6162\u6027\u75be\u60a3\u3002<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div id=\"preview-section-introduction\">\n<div class=\"PageDivider\"><\/div>\n<div class=\"Introduction u-font-serif text-s u-margin-l-ver\">\n<h2 class=\"u-h4 u-margin-s-bottom\">\u5c0e\u5165<\/h2>\n<section id=\"s0005\">\n<p id=\"p0005\">\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306f\u690d\u7269\u7531\u6765\u306e\u30d5\u30e9\u30dc\u30ce\u30a4\u30c9\u85ac\u3067\u3059\u3002\u00a0<em>\u30a8\u30ea\u30b2\u30ed\u30f3\u30fb\u30d6\u30ec\u30d3\u30b9\u30ab\u30d7\u30b9<\/em>\u00a0(Vant.) Hand.-Mazz.\u3001\u8907\u6570\u306e\u85ac\u7406\u52b9\u679c\u3068\u81e8\u5e8a\u5fdc\u7528\u3092\u6301\u3064\u6f22\u65b9\u85ac\u3002\u4e2d\u56fd\u5357\u897f\u90e8\u306e\u5c11\u6570\u6c11\u65cf\u30a4\u65cf\u3067\u306f\u3001\u8133\u5352\u4e2d\u306b\u3088\u308b\u9ebb\u75fa\u3084\u30ea\u30a6\u30de\u30c1\u306b\u3088\u308b\u95a2\u7bc0\u75db\u306e\u6cbb\u7642\u306b\u690d\u7269\u5168\u4f53\u304c\u4f55\u4e16\u4ee3\u306b\u3082\u308f\u305f\u3063\u3066\u4f7f\u7528\u3055\u308c\u3066\u304d\u307e\u3057\u305f\uff08Wang\u3001Yang\u3001Yang\u30012012\uff09\u3002\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306e\u69cb\u9020\u306f\u30015,6,7,4&#039;-\u30c6\u30c8\u30e9\u30d2\u30c9\u30ed\u30ad\u30b7\u30d5\u30e9\u30dc\u30f3 (\u30b9\u30af\u30c6\u30e9\u30ec\u30a4\u30f3\u3001S\u3001C) \u306e\u30b0\u30eb\u30af\u30ed\u30cb\u30c9\u7d50\u5408\u4f53\u3067\u3042\u308b\u3068\u6c7a\u5b9a\u3055\u308c\u307e\u3057\u305f\u3002<sub>15<\/sub>H<sub>10<\/sub>\u25cb<sub>6<\/sub>) 7-<em>\u25cb<\/em>\u00a0\u4f4d\u7f6e (scutellarein-7-<em>\u25cb<\/em>-\u30b0\u30eb\u30af\u30ed\u30cb\u30c9\u3001S-7-G\u3001C<sub>21<\/sub>H<sub>18<\/sub>\u25cb<sub>12<\/sub>\uff091\u4e16\u7d00\u524d\uff08\u56f31a\u304a\u3088\u3073b\uff09\u3002\u3057\u304b\u3057\u3001\u73fe\u4ee3\u533b\u5b66\u306b\u304a\u3051\u308b\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306e\u4f53\u7cfb\u7684\u306a\u7814\u7a76\u306f\u3001\u4e2d\u56fd\u304c\u4f1d\u7d71\u7684\u306a\u4e2d\u56fd\u533b\u5b66\u304b\u3089\u6cbb\u7642\u6cd5\u3092\u7279\u5b9a\u3057\u3001\u73fe\u4ee3\u5316\u3059\u308b\u305f\u3081\u306e\u5927\u898f\u6a21\u306a\u30ad\u30e3\u30f3\u30da\u30fc\u30f3\u3092\u958b\u59cb\u3057\u305f1970\u5e74\u4ee3\u5f8c\u534a\u307e\u3067\u59cb\u307e\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u3053\u306e\u30ad\u30e3\u30f3\u30da\u30fc\u30f3\u306f\u3001\u6f22\u65b9\u85ac\u7531\u6765\u306e\u6297\u30de\u30e9\u30ea\u30a2\u85ac\u30a2\u30eb\u30c6\u30df\u30b7\u30cb\u30f3\u306b\u4ee3\u8868\u3055\u308c\u308b\u3001\u81e8\u5e8a\u7684\u306b\u6210\u529f\u3092\u53ce\u3081\u305f\u6570\u591a\u304f\u306e\u85ac\u306e\u767a\u898b\u306b\u8ca2\u732e\u3057\u305f\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u00a0<em>\u30e8\u30e2\u30ae\u4e00\u5e74\u751f L.<\/em>\u00a0\uff08\u8ca1\u56e3\u30012015\uff09\u3002\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306f\u3001\u6b21\u306e\u4e3b\u8981\u306a\u6709\u52b9\u6210\u5206\u3068\u3057\u3066\u7279\u5b9a\u3055\u308c\u307e\u3057\u305f\u3002\u00a0<em>\u30a8\u30ea\u30b2\u30ed\u30f3\u30fb\u30d6\u30ec\u30d3\u30b9\u30ab\u30d7\u30b9<\/em>\u00a0\u3053\u308c\u3089\u306e\u521d\u671f\u306e\u7814\u7a76\u304b\u3089\u5f97\u3089\u308c\u305f\u3082\u306e\u3067\u3059\uff08Medica\u30011976; Wang et al.\u30012012\uff09\u3002\u30d6\u30ec\u30d3\u30b9\u30ab\u30d4\u30f3\u3001\u7dcf\u30d5\u30e9\u30dc\u30ce\u30a4\u30c9\u62bd\u51fa\u7269\u00a0<em>E. \u30d6\u30ec\u30d3\u30b9\u30ab\u30d7\u30b9<\/em>\u00a090%\u4ee5\u4e0a\u306e\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306810%\u4ee5\u4e0b\u306e\u30a2\u30d4\u30b2\u30cb\u30f3-7-O-\u30b0\u30eb\u30af\u30ed\u30cb\u30c9\u3092\u542b\u6709\u3059\u308b\u3082\u306e\u306f\u3001\u51e6\u65b9\u85ac\u3068\u3057\u3066\u5206\u985e\u3055\u308c\u307e\u3057\u305f\u3002\u73fe\u5728\u3001\u4e2d\u56fd\u3067\u306f\u6bce\u5e741,000\u4e07\u4eba\u4ee5\u4e0a\u306e\u60a3\u8005\u304c\u30d6\u30ec\u30d3\u30b9\u30ab\u30d4\u30f3\u304a\u3088\u3073\u95a2\u9023\u85ac\u3092\u4f7f\u7528\u3057\u3066\u3044\u308b(Liu et al., 2018)\u3002<\/p>\n<p id=\"p0010\">\u904e\u53bb 30 \u5e74\u9593\u306e\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306b\u95a2\u3059\u308b\u7814\u7a76\u306b\u3088\u308a\u3001\u8133\u8840\u7ba1\u75be\u60a3\u304a\u3088\u3073\u5fc3\u8840\u7ba1\u75be\u60a3\u3001\u7279\u306b\u865a\u8840\u6027\u8133\u5352\u4e2d\u3084\u51a0\u72b6\u52d5\u8108\u6027\u5fc3\u75be\u60a3\u306e\u6cbb\u7642\u306b\u304a\u3051\u308b\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306e\u6709\u52b9\u6027\u3092\u8a3c\u660e\u3059\u308b\u5927\u91cf\u306e\u8a3c\u62e0\u304c\u84c4\u7a4d\u3055\u308c\u307e\u3057\u305f\uff08\u4e2d\u56fd\u85ac\u5c40\u65b9\u59d4\u54e1\u4f1a\u30012015; Gao et al.\u30012017;Yang\u3001Cheng\u3001Xie\u3001Yang\u3001\u304a\u3088\u3073 Zhuang\u30012012;Yang\u3001Li\u3001Xie\u3001Zhuang\u3001\u304a\u3088\u3073 Yang\u30012013)\u3002\u81e8\u5e8a\u7814\u7a76\u304a\u3088\u3073\u5b9f\u9a13\u5ba4\u7814\u7a76\u3067\u306f\u3001\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u304c\u7cd6\u5c3f\u75c5\u5408\u4f75\u75c7\u306a\u3069\u306e\u4ed6\u306e\u3044\u304f\u3064\u304b\u306e\u6162\u6027\u75be\u60a3\u306e\u6cbb\u7642\u306b\u3082\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059 (Li, Wu, and Wang, 2009; Liu et al., 2016; Wu, Zhong, and Sun, 2002; Zheng, Ou, Shen \u3001\u5468\u3001\u738b\u30012015\uff09\u3002\u3055\u3089\u306b\u3001\u3053\u308c\u3089\u306e\u7814\u7a76\u306f\u3001\u30d2\u30c8\u3068\u52d5\u7269\u30e2\u30c7\u30eb\u306e\u4e21\u65b9\u306b\u304a\u3044\u3066\u3001\u85ac\u7269\u52d5\u614b\u5b66\u7684\u6319\u52d5\u3001\u4f5c\u7528\u6a5f\u5e8f\u3001\u85ac\u7269\u6a19\u7684\u3001\u6709\u5bb3\u53cd\u5fdc\u3092\u542b\u3080\u85ac\u7269\u306e\u85ac\u7406\u5b66\u7684\u5074\u9762\u306b\u3064\u3044\u3066\u306e\u91cd\u8981\u306a\u6d1e\u5bdf\u3092\u660e\u3089\u304b\u306b\u3057\u305f\uff08Gao et al., 2012; Gao, Chen, and Zhong \u30012011; Li\u3001Lin\u3001Xie\u3001Zhang\u3001Guo\u30012015; Li\u3001Wang\u3001Li\u3001Bai\u3001\u304a\u3088\u3073 Xue\u30012011; Lin et al.\u30012007; Yuan\u3001Fang\u3001Wu\u3001\u304a\u3088\u3073 Ling\u30012016; Yuan\u3001Zha \u3001\u30e9\u30f3\u30ac\u30e9\u30b8\u30e3\u30f3\u3001\u30ea\u30f3\u3001\u30a6\u30fc\u30012014\uff09\u3002\u3055\u3089\u306b\u3001\u8fd1\u5e74\u306e\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306e\u88fd\u5264\u3001\u85ac\u7269\u9001\u9054\u3001\u304a\u3088\u3073\u69cb\u9020\u4fee\u98fe\u306e\u9032\u6b69\u306b\u3088\u308a\u3001\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306e\u30d0\u30a4\u30aa\u30a2\u30d9\u30a4\u30e9\u30d3\u30ea\u30c6\u30a3\u3001\u6cbb\u7642\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3001\u6709\u52b9\u6027\u3001\u304a\u3088\u3073\u5b89\u5168\u6027\u3092\u6539\u5584\u3059\u308b\u65b0\u305f\u306a\u6a5f\u4f1a\u304c\u958b\u304b\u308c\u305f\uff08Lu et al., 2010\u3001Lu et al., 2012\uff09 ; Wang et al.\u30012017)\u3002\u3053\u306e\u8a18\u4e8b\u3067\u306f\u3001\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306e\u6cbb\u7642\u52b9\u679c\u3001\u85ac\u7269\u52d5\u614b\u3001\u304a\u3088\u3073\u85ac\u7406\u5b66\u7684\u6d3b\u6027\u3092\u5305\u62ec\u7684\u306b\u7406\u89e3\u3059\u308b\u305f\u3081\u306b\u3001\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306b\u95a2\u3059\u308b\u6587\u732e\u3092\u30ec\u30d3\u30e5\u30fc\u3057\u307e\u3059\u3002<\/p>\n<\/section>\n<\/div>\n<\/div>\n<div id=\"preview-section-snippets\">\n<div class=\"PageDivider\"><\/div>\n<div class=\"Snippets u-font-serif text-s\">\n<h2 class=\"u-h4 u-margin-l-ver\">\u30bb\u30af\u30b7\u30e7\u30f3\u306e\u629c\u7c8b<\/h2>\n<section>\n<section id=\"s0010\">\n<h2 class=\"section-title u-h4 u-margin-l-top u-margin-xs-bottom\">\u6cbb\u7642\u52b9\u679c\u3068\u81e8\u5e8a\u4e0a\u306e\u5229\u76ca<\/h2>\n<p id=\"p0015\"><em>\u30a8\u30ea\u30b2\u30ed\u30f3\u30fb\u30d6\u30ec\u30d3\u30b9\u30ab\u30d7\u30b9<\/em>\u00a0(Vant.) Hand.-Mazz.\u3001\u3068\u3057\u3066\u3082\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u00a0<em>\u30cf\u30fc\u30d0\u30fb\u30a8\u30ea\u30b2\u30ed\u30f3\u30c6\u30a3\u30b9<\/em>,\u00a0<em>\u30e9\u30f3\u30d7\u83ca<\/em>\u3001\u304a\u3088\u3073\u30d2\u30e1\u30d0\u30cd\u3001\u307e\u305f\u306f\u4e2d\u56fd\u8a9e\u3067dengzhanxixin\u304a\u3088\u3073dengzhanhua\u306f\u3001\u4e2d\u56fd\u5357\u897f\u90e8\u306e\u591a\u304f\u306e\u5c71\u5cb3\u5730\u5e2f\u3067\u898b\u3089\u308c\u307e\u3059\u3002\u30a4\u30fc\u65cf\u306b\u3088\u308b\u9ebb\u75fa\u3084\u30ea\u30a6\u30de\u30c1\u306e\u6cbb\u7642\u306b\u52a0\u3048\u3066\u3001\u3053\u306e\u6f22\u65b9\u85ac\u306f\u30a4\u30fc\u65cf\u3001\u30c1\u30ef\u30f3\u65cf\u3001\u30c1\u30d9\u30c3\u30c8\u65cf\u306e\u5c11\u6570\u6c11\u65cf\u306b\u3088\u308b\u982d\u75db\u3001\u6b6f\u75db\u3001\u80c3\u708e\u3001\u767a\u71b1\u306e\u6cbb\u7642\u306b\u3082\u4f55\u767e\u5e74\u3082\u4f7f\u7528\u3055\u308c\u3066\u304d\u307e\u3057\u305f\uff08Medica\u30011976; Wang et al. \u30012012\uff09\u3002<\/p>\n<p id=\"p0020\">\u6cbb\u7642\u6cd5\u306e\u958b\u767a\u00a0<em>E.<\/em><\/p>\n<\/section>\n<\/section>\n<section>\n<section id=\"s0075\">\n<h2 class=\"section-title u-h4 u-margin-l-top u-margin-xs-bottom\">\u85ac\u7269\u52d5\u614b<\/h2>\n<p id=\"p0135\">\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306f\u3001\u30d2\u30c8\u304a\u3088\u3073\u52d5\u7269\u306b\u304a\u3044\u3066\u7570\u5e38\u306a\u85ac\u7269\u52d5\u614b\u5b66\u7684\u6319\u52d5\u3092\u793a\u3057\u307e\u3059\u3002\u591a\u304f\u306e\u690d\u7269\u7531\u6765\u306e\u30d5\u30e9\u30dc\u30ce\u30a4\u30c9 \u30b0\u30eb\u30af\u30ed\u30cb\u30c9\u3068\u540c\u69d8\u306b\u3001\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306f\u4f53\u6db2\u4e2d\u3067\u306e\u6eb6\u89e3\u5ea6\u304c\u4f4e\u304f\u3001\u751f\u7269\u5b66\u7684\u5229\u7528\u80fd\u304c\u597d\u307e\u3057\u304f\u306a\u304f\u3001\u54fa\u4e73\u52d5\u7269\u7cfb\u3067\u306e\u534a\u6e1b\u671f\u304c\u77ed\u3044\u3067\u3059\u3002\u7d4c\u53e3\u6295\u4e0e\u5f8c\u306e\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306e\u8840\u6f3f\u6fc3\u5ea6\u304c\u975e\u5e38\u306b\u4f4e\u3044\u3053\u3068\u304b\u3089\u308f\u304b\u308b\u3088\u3046\u306b\u3001\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306e\u751f\u7269\u5b66\u7684\u5229\u7528\u80fd\u306f\u975e\u5e38\u306b\u4f4e\u3044\u3067\u3059\u3002 20\u4eba\u306e\u5065\u5eb7\u306a\u30dc\u30e9\u30f3\u30c6\u30a3\u30a2\u306b60mg\u306e\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u3092\u7d4c\u53e3\u6295\u4e0e\u3057\u305f\u7814\u7a76\u3067\u306f\u3001\u89aa\u85ac\u304c<\/p>\n<\/section>\n<\/section>\n<section>\n<section id=\"s0100\">\n<h2 class=\"section-title u-h4 u-margin-l-top u-margin-xs-bottom\">\u85ac\u7406\u52b9\u679c<\/h2>\n<p id=\"p0220\">\u904e\u53bb 30 \u5e74\u9593\u3001\u5b9f\u9a13\u7cfb\u306b\u304a\u3051\u308b\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306e\u85ac\u7406\u5b66\u7684\u52b9\u679c\u3092\u6587\u66f8\u5316\u3057\u3066\u7406\u89e3\u3059\u308b\u305f\u3081\u306b\u591a\u5927\u306a\u52aa\u529b\u304c\u6255\u308f\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u7279\u306b\u3001\u591a\u304f\u306e\u6700\u8fd1\u306e\u7814\u7a76\u306b\u3088\u308a\u3001\u52d5\u7269\u30e2\u30c7\u30eb\u306b\u304a\u3051\u308b\u8133\u865a\u8840\u6027\u8133\u5352\u4e2d\u3001\u51a0\u72b6\u52d5\u8108\u6027\u5fc3\u75be\u60a3\u3001\u304a\u3088\u3073\u7cd6\u5c3f\u75c5\u6027\u5408\u4f75\u75c7\u306b\u5bfe\u3059\u308b\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u304a\u3088\u3073\u95a2\u9023\u85ac\u5264\u306e\u6cbb\u7642\u52b9\u679c\u306e\u5b9a\u91cf\u7684\u6e2c\u5b9a\u304c\u63d0\u4f9b\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u5b9f\u9a13\u30c7\u30fc\u30bf\u306f\u3001\u4ed6\u306e\u3044\u304f\u3064\u304b\u306e\u75c5\u6c17\u306e\u6cbb\u7642\u306b\u304a\u3051\u308b\u85ac\u5264\u306e\u6709\u76ca\u306a\u52b9\u679c\u3082\u88cf\u4ed8\u3051\u3066\u3044\u307e\u3059\u3002<\/p>\n<\/section>\n<\/section>\n<section>\n<section id=\"s0165\">\n<h2 class=\"section-title u-h4 u-margin-l-top u-margin-xs-bottom\">\u30e1\u30ab\u30cb\u30ba\u30e0\u3001\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u7d4c\u8def\u3001\u5206\u5b50\u6a19\u7684<\/h2>\n<p id=\"p0330\">\u85ac\u8349\u306e\u4f5c\u7528\u6a5f\u5e8f\u3092\u89e3\u660e\u3057\u3001\u85ac\u8349\u306e\u6a19\u7684\u7d4c\u8def\u3068\u5206\u5b50\u3092\u540c\u5b9a\u3059\u308b\u3053\u3068\u306f\u3001\u85ac\u8349\u306e\u6cbb\u7642\u7528\u9014\u3092\u6539\u5584\u3059\u308b\u305f\u3081\u306b\u5fc5\u8981\u304b\u3064\u91cd\u8981\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u591a\u5927\u306a\u52aa\u529b\u304c\u6255\u308f\u308c\u3066\u3044\u308b\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001\u3053\u308c\u3089\u306e\u5e0c\u671b\u7684\u89b3\u6e2c\u306f\u3001\u307b\u3068\u3093\u3069\u306e\u6f22\u65b9\u85ac\u7531\u6765\u306e\u6cbb\u7642\u6cd5\u306b\u3068\u3063\u3066\u4f9d\u7136\u3068\u3057\u3066\u5927\u304d\u306a\u8ab2\u984c\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u90e8\u5206\u7684\u306b\u306f\u3001\u307b\u3068\u3093\u3069\u306e\u6f22\u65b9\u85ac\u304c\u5408\u7406\u7684\u306a\u85ac\u5264\u8a2d\u8a08\u3067\u306f\u306a\u304f\u7d4c\u9a13\u3092\u901a\u3058\u3066\u9032\u5316\u3057\u3001\u6642\u306b\u306f\u6b21\u306e\u3088\u3046\u306a\u62bd\u8c61\u7684\u306a\u6982\u5ff5\u306b\u57fa\u3065\u3044\u3066\u3044\u308b\u3068\u3044\u3046\u4e8b\u5b9f\u306b\u3088\u308b\u3082\u306e\u3067\u3059\u3002<\/p>\n<\/section>\n<\/section>\n<section>\n<section id=\"s0255\">\n<h2 class=\"section-title u-h4 u-margin-l-top u-margin-xs-bottom\">\u6bd2\u6027<\/h2>\n<p id=\"p0530\">\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u3068\u30d6\u30ec\u30d3\u30b9\u30ab\u30d4\u30f3\u306f\u3001\u52d5\u7269\u306b\u5bfe\u3057\u3066\u6bd2\u6027\u304c\u307b\u3068\u3093\u3069\u306a\u3044\u304b\u3001\u307e\u305f\u306f\u7121\u6bd2\u3067\u3059\u3002\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306e\u6700\u5927\u8010\u7528\u91cf\u306f\u30de\u30a6\u30b9\u3067\u306f &gt;10 g\/kg \u3067\u3042\u308a\u3001\u3057\u305f\u304c\u3063\u3066\u305d\u306e\u6025\u6027\u81f4\u6b7b\u91cf (LD) \u3067\u3042\u308b\u3053\u3068\u304c\u5224\u660e\u3057\u307e\u3057\u305f\u3002<sub>50<\/sub>\uff09\u306f\u5b9f\u9a13\u7684\u306b\u6c7a\u5b9a\u3067\u304d\u307e\u305b\u3093\u3067\u3057\u305f\uff08Li et al.\u30012011\uff09\u3002\u4e9c\u6025\u6027\u7814\u7a76\u3067\u306f\u3001\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u3092\u6bce\u65e5 100 \u307e\u305f\u306f 500 mg\/kg \u306e\u7528\u91cf\u3067\u6700\u5927 30 \u65e5\u9593\u7d4c\u53e3\u6295\u4e0e\u3057\u3066\u3082\u3001\u7528\u91cf\u306b\u95a2\u4fc2\u3057\u306a\u3044\u6e1b\u5c11\u3092\u9664\u3044\u3066\u3001\u6b7b\u4ea1\u3084\u8840\u6db2\u5b66\u3001\u8840\u6db2\u5316\u5b66\u3001\u304a\u3088\u3073\u5c3f\u691c\u67fb\u306e\u91cd\u5927\u306a\u5909\u5316\u306f\u751f\u3058\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n<\/section>\n<\/section>\n<section>\n<section id=\"s0260\">\n<section id=\"s0265\">\n<section id=\"s0270\">\n<h2 class=\"section-title u-h4 u-margin-l-top u-margin-xs-bottom\">\u4e21\u89aa\u5a92\u6027\u8a98\u5c0e\u4f53\u3092\u542b\u3080\u30ca\u30ce\u7c92\u5b50\u62c5\u4f53<\/h2>\n<p id=\"p0545\">\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306f\u7cd6\u5c3f\u75c5\u6027\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u6a5f\u80fd\u4e0d\u5168\u306e\u6cbb\u7642\u306b\u6709\u52b9\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u305d\u306e\u81e8\u5e8a\u5fdc\u7528\u306f\u7d4c\u53e3\u30d0\u30a4\u30aa\u30a2\u30d9\u30a4\u30e9\u30d3\u30ea\u30c6\u30a3\u30fc\u304c\u4f4e\u3044\u305f\u3081\u306b\u5236\u9650\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u3092\u62c5\u6301\u3057\u305f\u4e21\u89aa\u5a92\u6027\u30ad\u30c8\u30b5\u30f3\u8a98\u5c0e\u4f53\u3092\u542b\u3080\u65b0\u898f\u306a\u8178\u6a19\u7684\u30ca\u30ce\u7c92\u5b50\u62c5\u4f53\uff08Chit-DC-VB12-Scu\uff09\u306f\u3001\u5b9f\u9a13\u7684\u7cd6\u5c3f\u75c5\u6027\u7db2\u819c\u75c7\u306b\u304a\u3051\u308b\u6cbb\u7642\u52b9\u679c\u306b\u5bfe\u3059\u308b\u30b9\u30af\u30c6\u30e9\u30ea\u30f3\u306e\u751f\u7269\u5b66\u7684\u5229\u7528\u80fd\u3092\u9ad8\u3081\u308b\u305f\u3081\u306b\u4f5c\u6210\u3055\u308c\u305f\uff08Wang et al., 2017\uff09\u3002\u30e9\u30c3\u30c8\u306e\u30d0\u30a4\u30aa\u30a2\u30d9\u30a4\u30e9\u30d3\u30ea\u30c6\u30a3\u7814\u7a76\u306b\u3088\u308a\u3001\u6b21\u306e\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section>\n<section id=\"s0305\">\n<h2 class=\"section-title u-h4 u-margin-l-top u-margin-xs-bottom\">\u7d50\u8ad6<\/h2>\n<p id=\"p0575\">\u4f1d\u7d71\u7684\u306a\u6f22\u65b9\u85ac\u304b\u3089\u306e\u6cbb\u7642\u85ac\u306e\u958b\u767a\u306f\u3001\u8133\u865a\u8840\u3084\u5fc3\u7b4b\u865a\u8840\u3001\u7cd6\u5c3f\u75c5\u6027\u5408\u4f75\u75c7\u3001\u795e\u7d4c\u5909\u6027\u3001\u764c\u306a\u3069\u306e\u3055\u307e\u3056\u307e\u306a\u75be\u60a3\u3084\u75c5\u72b6\u306e\u6cbb\u7642\u306b\u304a\u3051\u308b\u6709\u671b\u306a\u65b9\u5411\u6027\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u7406\u7531\u306e\u4e00\u90e8\u306f\u3001\u3053\u308c\u3089\u306e\u75c5\u6c17\u306e\u75c5\u7406\u5b66\u7684\u9032\u5c55\u304c\u8907\u96d1\u3067\u3042\u308a\u3001\u3088\u304f\u7406\u89e3\u3055\u308c\u3066\u3044\u306a\u3044\u8907\u6570\u306e\u6a5f\u80fd\u3068\u69cb\u9020\u9593\u306e\u52d5\u7684\u306a\u76f8\u4e92\u4f5c\u7528\u304c\u95a2\u4e0e\u3057\u3066\u3044\u308b\u305f\u3081\u3067\u3059\u3002\u3053\u306e\u8907\u96d1\u3055\u306f\u591a\u304f\u306e\u5834\u5408\u3001\u306f\u308b\u304b\u306b\u8907\u96d1\u3067\u3059<\/p>\n<\/section>\n<\/section>\n<section>\n<section id=\"s0310\">\n<h2 class=\"section-title u-h4 u-margin-l-top u-margin-xs-bottom\">\u4e86\u627f<\/h2>\n<p id=\"p0615\">\u3053\u306e\u7814\u7a76\u306f\u3001LW \u3078\u306e\u4ee5\u4e0b\u306e\u52a9\u6210\u91d1\u306b\u3088\u3063\u3066\u652f\u63f4\u3055\u308c\u307e\u3057\u305f: (a) \u304b\u3089\u306e 81660551\u00a0<span id=\"gts0005\">\u4e2d\u56fd\u56fd\u5bb6\u81ea\u7136\u79d1\u5b66\u8ca1\u56e3<\/span>; (b) 2014FB151\u3088\u308a\u00a0<span id=\"gts0010\">\u96f2\u5357\u7701\u5fdc\u7528\u57fa\u790e\u7814\u7a76\u30d7\u30ed\u30b8\u30a7\u30af\u30c8<\/span>,\u00a0<span id=\"gts0015\">\u4e2d\u56fd\u96f2\u5357\u7701\u79d1\u5b66\u6280\u8853\u5c40<\/span>;\u304a\u3088\u3073 (c) 2017FE467(-126) \u96f2\u5357\u5fdc\u7528\u57fa\u790e\u7814\u7a76\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u3088\u308a-<span id=\"gts0020\">\u30e6\u30cb\u30aa\u30f3\u8ca1\u56e3<\/span>,\u00a0<span id=\"gts0025\">\u96f2\u5357\u7701\u79d1\u5b66\u6280\u8853\u5c40<\/span>\u00a0\u305d\u3057\u3066\u00a0<span id=\"gts0030\">\u6606\u660e\u533b\u79d1\u5927\u5b66\u3001\u4e2d\u56fd<\/span>;\u304a\u3088\u3073\u56fd\u7acb\u52b4\u50cd\u5b89\u5168\u7814\u7a76\u6240\u304b\u3089\u306e QM \u3078\u306e\u52a9\u6210\u91d1: 7939050W<\/p>\n<\/section>\n<\/section>\n<section>\n<section id=\"s0315\">\n<h2 class=\"section-title u-h4 u-margin-l-top u-margin-xs-bottom\">\u514d\u8cac\u4e8b\u9805<\/h2>\n<p id=\"p0620\">\u3053\u306e\u5831\u544a\u66f8\u306e\u8abf\u67fb\u7d50\u679c\u3068\u7d50\u8ad6\u306f\u8457\u8005\u3089\u306e\u898b\u89e3\u3067\u3042\u308a\u3001\u5fc5\u305a\u3057\u3082\u56fd\u7acb\u52b4\u50cd\u5b89\u5168\u885b\u751f\u7814\u7a76\u6240\u306e\u898b\u89e3\u3092\u8868\u3059\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<\/section>\n<\/section>\n<section>\n<section id=\"s0320\">\n<h2 class=\"section-title u-h4 u-margin-l-top u-margin-xs-bottom\">\u5229\u76ca\u76f8\u53cd\u306b\u95a2\u3059\u308b\u58f0\u660e<\/h2>\n<p id=\"p0625\">\u8457\u8005\u306f\u5229\u76ca\u76f8\u53cd\u304c\u306a\u3044\u3053\u3068\u3092\u5ba3\u8a00\u3057\u307e\u3059\u3002<\/p>\n<\/section>\n<\/section>\n<\/div>\n<\/div>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0163725818300809#:~:text=Owing%20to%20its%20multiple%20beneficial,myocardial%20infarction%2C%20and%20diabetic%20complications\">\u30bd\u30fc\u30b9<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Stroke and myocardial infarction are among the most common causes of mortality and disability in the world. The ischemic injury underlying these illnesses is complex, involving intricate interplays among many biological functions including energy metabolism, vascular regulation,<\/p>","protected":false},"author":1,"featured_media":5369,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[9],"tags":[],"class_list":["post-5163","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-supplements"],"_links":{"self":[{"href":"https:\/\/directcm.com\/ja\/wp-json\/wp\/v2\/posts\/5163","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/directcm.com\/ja\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/directcm.com\/ja\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/directcm.com\/ja\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/directcm.com\/ja\/wp-json\/wp\/v2\/comments?post=5163"}],"version-history":[{"count":1,"href":"https:\/\/directcm.com\/ja\/wp-json\/wp\/v2\/posts\/5163\/revisions"}],"predecessor-version":[{"id":5376,"href":"https:\/\/directcm.com\/ja\/wp-json\/wp\/v2\/posts\/5163\/revisions\/5376"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/directcm.com\/ja\/wp-json\/wp\/v2\/media\/5369"}],"wp:attachment":[{"href":"https:\/\/directcm.com\/ja\/wp-json\/wp\/v2\/media?parent=5163"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/directcm.com\/ja\/wp-json\/wp\/v2\/categories?post=5163"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/directcm.com\/ja\/wp-json\/wp\/v2\/tags?post=5163"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}