{"id":4897,"date":"2024-01-15T06:31:30","date_gmt":"2024-01-15T06:31:30","guid":{"rendered":"https:\/\/corp.farlong.com\/the-effect-of-proto-type-wearable-light-emitting-devices-on-serum-25-hydroxyvitamin-d-levels-in-healthy-adults-a-4-week-randomized-controlled-trial\/"},"modified":"2024-01-27T10:17:53","modified_gmt":"2024-01-27T10:17:53","slug":"the-effect-of-proto-type-wearable-light-emitting-devices-on-serum-25-hydroxyvitamin-d-levels-in-healthy-adults-a-4-week-randomized-controlled-trial","status":"publish","type":"post","link":"https:\/\/directcm.com\/ko\/the-effect-of-proto-type-wearable-light-emitting-devices-on-serum-25-hydroxyvitamin-d-levels-in-healthy-adults-a-4-week-randomized-controlled-trial\/","title":{"rendered":"\uac74\uac15\ud55c \uc131\uc778\uc758 \ud608\uccad 25-\ud558\uc774\ub4dc\ub85d\uc2dc\ube44\ud0c0\ubbfc D \uc218\uce58\uc5d0 \ub300\ud55c \ud504\ub85c\ud1a0\ud0c0\uc785 \uc6e8\uc5b4\ub7ec\ube14 \ubc1c\uad11 \uc7a5\uce58\uc758 \ud6a8\uacfc: 4\uc8fc \ubb34\uc791\uc704 \ub300\uc870 \uc2dc\ud5d8"},"content":{"rendered":"
\n

\uc5f0\uad6c \uc778\uad6c<\/h3>\n

\ubcf8 \uc5f0\uad6c\ub294 \ub300\ud55c\ubbfc\uad6d \uc131\ub0a8\uc5d0 \uc704\uce58\ud55c \ubd84\ub2f9\uc11c\uc6b8\ub300\ud559\uad50\ubcd1\uc6d0(SNUBH) \uc218\uba74\ud074\ub9ac\ub2c9\uc5d0\uc11c \uc9c4\ud589\ub418\uc5c8\uc2b5\ub2c8\ub2e4. 20~65\uc138\uc758 \uac74\uac15\ud55c \uc131\uc778\uc744 2020\ub144 8\uc6d4\ubd80\ud130 2021\ub144 8\uc6d4\uae4c\uc9c0 \uc9c0\uc5ed\uc0ac\ud68c \uad11\uace0\ub97c \ud1b5\ud574 \ubaa8\uc9d1\ud588\uc2b5\ub2c8\ub2e4. \ub4f1\ub85d\ub41c \ucc38\uac00\uc790\ub294 \uac1c\uc785 \uc2dc\uc791 1\uc8fc\uc77c \uc804\uc778 \uccab \ubc88\uc9f8 \ubc29\ubb38\uc5d0\uc11c \uc120\ubcc4\uac80\uc0ac\ub97c \ubc1b\uc558\uc2b5\ub2c8\ub2e4. \uc2a4\ud06c\ub9ac\ub2dd \uc2dc\ud5d8\uc5d0\uc11c \ud53c\ubd80\uc774\uc0c1\ubc18\uc751\uc744 \uacbd\ud5d8\ud55c \uc790\ub294 \uc81c\uc678\ud558\uc600\ub2e4. \ub610\ud55c \ub2e4\uc74c \uae30\uc900\uc744 \ucda9\uc871\ud558\ub294 \uc0ac\ub78c\ub4e4\ub3c4 \uc81c\uc678\ud588\uc2b5\ub2c8\ub2e4: (1) \uc5f0\uad6c \uc2dc\uc791 \uc804 2\uac1c\uc6d4 \uc774\ub0b4\uc5d0 \uad11\uc120 \uc694\ubc95 \ub610\ub294 \ube44\ud0c0\ubbfc D \ubcf4\ucda9 \uc774\ub825; (2) \ud53c\ubd80\uc554 \ubc0f \uad11\uacfc\ubbfc\uc131\uc744 \ud3ec\ud568\ud55c \ud53c\ubd80 \uc9c8\ud658; (3) \uc545\uc131 \uc885\uc591, \ud638\ud761\uae30 \uc9c8\ud658, \uc804\uc5fc\ubcd1, \uac04 \ub610\ub294 \uc2e0\uc7a5 \uc7a5\uc560, \ub450\ubd80 \uc678\uc0c1 \ub4f1\uc758 \uc758\ud559\uc801 \uc9c8\ubcd1; \ubc0f (4) \uae30\ubd84 \uc7a5\uc560, \ubd88\uc548 \uc7a5\uc560, \uc218\uba74 \uc7a5\uc560 \ubc0f \uc815\uc2e0\ubcd1\uc801 \uc7a5\uc560\ub97c \ud3ec\ud568\ud558\ub294 \uc815\uc2e0 \uc7a5\uc560. \uc5f0\uad6c\uac00 \uc2dc\uc791\ub418\uae30 \uc804\uc5d0 \ubaa8\ub4e0 \ucc38\uac00\uc790\ub85c\ubd80\ud130 \uc11c\uba74 \ub3d9\uc758\ub97c \uc5bb\uc5c8\uc2b5\ub2c8\ub2e4. \ubcf8 \uc5f0\uad6c\ub294 SNUBH \uae30\uad00\uc2ec\uc0ac\uc704\uc6d0\ud68c(B-2002-597-003)\uc758 \uc2b9\uc778\uc744 \ubc1b\uc558\uc73c\uba70 \ub300\ud55c\ubbfc\uad6d \uc784\uc0c1\uc5f0\uad6c\uc815\ubcf4\uc11c\ube44\uc2a4(CRIS)\uc5d0 \ub4f1\ub85d\ub418\uc5c8\uc2b5\ub2c8\ub2e4(\ub4f1\ub85d\ubc88\ud638 KCT0007033).<\/p>\n

\uac04\uc12d<\/h3>\n

\uc6b0\ub9ac\ub294 \ub300\ud55c\ubbfc\uad6d \ub300\uc804\uc5d0 \uc788\ub294 \ud55c\uad6d\uacfc\ud559\uae30\uc220\uc6d0 \uc804\uae30\uacf5\ud559\ubd80\uc5d0\uc11c \ub9de\ucda4 \uc124\uacc4\ub41c \ub450 \uac00\uc9c0 \uc720\ud615\uc758 \ud504\ub85c\ud1a0\ud0c0\uc785 \uc6e8\uc5b4\ub7ec\ube14 \ubc1c\uad11 \uc7a5\uce58(\ub2a5\ub3d9 \uc7a5\uce58\uc640 \uac00\uc9dc \uc7a5\uce58)\ub97c \uc0ac\uc6a9\ud588\uc2b5\ub2c8\ub2e4. \ub2a5\ub3d9 \uc7a5\uce58\ub294 11nm\uc758 \uc808\ubc18 \ucd5c\ub300 \ud3ed\uc5d0\uc11c 285nm\uc758 \ud53c\ud06c \ud30c\uc7a5\uc5d0\uc11c UVB \uad11\uc744 \ubc29\ucd9c\ud558\ub294 48\uac1c\uc758 LED(QD Jason, \uc911\uad6d, \ubaa8\ub378 J35ABA285P09A)\ub85c \uad6c\uc131\ub418\uc5c8\uc2b5\ub2c8\ub2e4. LED\ub294 FPCB(Flexible Printed Circuit Board) \uc704\uc5d0 \uc778\uc811\ud55c LED \uc0ac\uc774\uc5d0 13mm \uac04\uaca9\uc73c\ub85c 6\u00d78 \ub9e4\ud2b8\ub9ad\uc2a4 \ud615\uc2dd\uc73c\ub85c \ubc30\uc5f4\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uadf8\ub7f0 \ub2e4\uc74c \uc774 48\uac1c\uc758 UVB LED\uac00 \ud3ec\ud568\ub41c FPCB\ub97c \uc544\ub798\ucabd \ub610\ub294 \uc704\ucabd \ud314\uc744 \uac10\uc300 \uc218 \uc788\ub294 3D \ud504\ub9b0\ud305 \ud558\uc6b0\uc9d5\uc5d0 \ubc30\uce58\ud588\uc2b5\ub2c8\ub2e4. LED\uc758 \ube5b\uc774 \ud53c\ubd80 \uc704\ub85c \ud37c\uc9c8 \uc218 \uc788\ub3c4\ub85d LED\uc640 \uc870\uba85 \uc544\ub798 \ud53c\ubd80 \ud45c\uba74 \uc0ac\uc774\uc758 \uac70\ub9ac\ub97c ~5mm\ub85c \uc720\uc9c0\ud588\uc2b5\ub2c8\ub2e4. \ub610\ud55c, LED\uc640 \ud53c\ubd80 \ud45c\uba74 \uc0ac\uc774\uc5d0 \ud3f4\ub9ac\ub514\uba54\ud2f8\uc2e4\ub85d\uc0b0(PDMS)\uc758 \ud22c\uba85\ud55c \uc5d8\ub77c\uc2a4\ud1a0\uba38\ub97c \ubc30\uce58\ud558\uc5ec \ud53c\ubd80\uc640 LED\uc758 \uac70\ub9ac\uac00 \uc77c\uc815\ud558\uac8c \uc720\uc9c0\ub418\ub3c4\ub85d \ud588\uc2b5\ub2c8\ub2e4. PDMS \uce35\uc758 \ud55c \uba74\uc740 LED \ube5b\uc758 \ud655\uc0b0\uc744 \ub354\uc6b1 \ud5a5\uc0c1\uc2dc\ud0a4\uae30 \uc704\ud574 \ubbf8\uc138 \uad6c\uc870\ub85c \ub9cc\ub4e4\uc5b4\uc84c\uc2b5\ub2c8\ub2e4. \uc804\uccb4 \uc870\uba85 \uc601\uc5ed\uc740 ~ 80 cm2<\/sup>. \uad11\ud655\uc0b0 \uad6c\uc870\ub294 ~7.8mJ\/cm\uc758 \uc120\ub7c9\uc744 \uacac\ub51c \uc218 \uc788\uc2b5\ub2c8\ub2e4.2<\/sup> 1\ubd84 \ub178\ucd9c\ub2f9. \uac00\uc9dc \uc7a5\uce58\ub294 LED\uac00 UVB \uad11 \ub300\uc2e0 465 nm\uc758 \ud53c\ud06c \ud30c\uc7a5\uc744 \uac16\ub294 \uccad\uc0c9 \uad11\uc744 \ubc29\ucd9c\ud55c\ub2e4\ub294 \uc810\uc744 \uc81c\uc678\ud558\uace0\ub294 \ub3d9\uc77c\ud55c \uad6c\uc870\ub97c \uac00\uc9c0\uace0 \uc788\uc5c8\uc2b5\ub2c8\ub2e4(\uadf8\ub9bc 1). 1<\/a>).<\/p>\n

\n
\uadf8\ub9bc 1: \ud504\ub85c\ud1a0\ud0c0\uc785 \uc6e8\uc5b4\ub7ec\ube14 \uc7a5\uce58\uc758 \uc0ac\uc9c4.<\/b><\/figcaption>
\n
\"figure<\/picture><\/a><\/div>\n
\n

\u314f<\/b> \ub9de\ucda4\ud615 \ucee8\ud2b8\ub864\ub7ec\ub97c \uac16\ucd98 \uc81c\uc548\ub41c \uc790\uc678\uc120 B \uc6e8\uc5b4\ub7ec\ube14 \uc7a5\uce58\uc758 \uc0ac\uc9c4. \ube44<\/b> \ud314\ub69d\uc5d0 \ucc29\uc6a9\ud55c \uc790\uc678\uc120 B \uc6e8\uc5b4\ub7ec\ube14 \uae30\uae30\uc758 \uc0ac\uc9c4.<\/p>\n<\/div>\n<\/div>\n<\/figure>\n<\/div>\n

\uccab \ubc88\uc9f8 \ubc29\ubb38 \uc2dc \ub2a5\ub3d9 \uc18c\uc790\uc640 \ub3d9\uc77c\ud55c \ud30c\uc7a5 \ubc0f \uac15\ub3c4\uc758 UVB \uad11\uc744 \ubc29\ucd9c\ud558\ub294 \ub2e8\uc77c LED\ub85c \uad6c\uc131\ub41c \ud14c\uc2a4\ud2b8 \uc7a5\uce58\ub97c \uc0ac\uc6a9\ud558\uc5ec 3cm \ud06c\uae30\uc758 \uc2a4\ud06c\ub9b0\uc5d0 \uc2a4\ud06c\ub9ac\ub2dd \ud14c\uc2a4\ud2b8\ub97c \uc218\ud589\ud588\uc2b5\ub2c8\ub2e4.2<\/sup> \ud314\ub69d \ud53c\ubd80 \ubd80\uc704. \uadf8 \ud6c4, \uc801\uaca9 \ucc38\uac00\uc790\ub97c \uc2e4\ud5d8\uad70 \ub610\ub294 \ub300\uc870\uad70\uc5d0 1:1 \ube44\uc728\ub85c \ubb34\uc791\uc704\ub85c \ud560\ub2f9\ud558\uace0 \uac1c\uc785 \ud560\ub2f9\uc5d0 \ub300\ud574 \ub208\uc774 \uba40\uac8c \ud588\uc2b5\ub2c8\ub2e4. \ubb34\uc791\uc704 \ud560\ub2f9\uc740 \uacc4\uce35\ud654\ub41c \uc21c\uc5f4 \ube14\ub85d \ubb34\uc791\uc704\ud654 \ubc29\ubc95\uc744 \ud1b5\ud574 \uc81c3\uc790\uc5d0 \uc758\ud574 \uc218\ud589\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uccab \ubc88\uc9f8 \ubc29\ubb38 \ud6c4 \uc77c\uc8fc\uc77c \uc774\ub0b4\uc5d0 \uc774\ub8e8\uc5b4\uc9c4 \ub450 \ubc88\uc9f8 \ubc29\ubb38\uc5d0\uc11c \ucc38\uac00\uc790\ub4e4\uc740 \ubb34\uc791\uc704 \uadf8\ub8f9 \ud560\ub2f9\uc5d0 \ub530\ub77c \ud65c\uc131 \uc7a5\uce58 \ub610\ub294 \uac00\uc9dc \uc7a5\uce58\ub97c \ubc1b\uc558\uc2b5\ub2c8\ub2e4. \uadf8\ub4e4\uc740 4\uc8fc \ub3d9\uc548 \ub9e4\uc77c \uc591\ucabd \ud314\ub69d\uc5d0 1\ubd84\uc529 \ucd1d 2\ubd84 \ub3d9\uc548 \uc7a5\uce58\ub97c \ucc29\uc6a9\ud558\ub3c4\ub85d \uc9c0\uc2dc\ubc1b\uc558\ub2e4. \uac01 \ud314\uc758 1\ubd84\uac04 UV \ub178\ucd9c\uc740 \uc7a5\uce58\uc758 \ucee8\ud2b8\ub864\ub7ec \uc7a5\uce58\uc5d0 \uc758\ud574 \uc81c\uc5b4\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c \ud65c\uc131 \uc7a5\uce58\uc5d0 \uc758\ud55c UVB \ubc29\uc0ac\uc120\uc758 \ub2e8\uc704 \uba74\uc801\ub2f9 \uc77c\uc77c \ubcf5\uc6a9\ub7c9\uc740 \uc57d 7.8mJ\/cm\ub85c \uacb0\uc815\ub418\uc5c8\uc2b5\ub2c8\ub2e4.2<\/sup>, \uc720\ud6a8 \ub178\ucd9c \uba74\uc801\uc740 ~ 80 cm2<\/sup> \uac01 \ud314\ub69d\uc5d0 \ub300\ud574 \uc77c\uc77c \ucd1d \ubcf5\uc6a9\ub7c9\uc740 1.25J(=7.8mJ\/cm)\uac00 \ub429\ub2c8\ub2e4.2<\/sup> \u00d7 80cm2<\/sup>\u00d7 2). \ucc38\uac00\uc790\uc758 \uc548\uc804\uc744 \uc704\ud574 \uc911\uc7ac \uc2dc\uc791 \ud6c4 \uac01\uac01 2\uc8fc\uc640 4\uc8fc\uc5d0 \uc774\ub8e8\uc5b4\uc9c4 3\ucc28 \ubc0f 4\ucc28 \ubc29\ubb38\uc5d0\uc11c \ubd80\uc791\uc6a9 \ubc1c\uc0dd \ubc0f \uc7a5\uce58 \uc0ac\uc6a9 \uc900\uc218 \uc5ec\ubd80\ub97c \ubaa8\ub2c8\ud130\ub9c1\ud588\uc2b5\ub2c8\ub2e4. \uc911\uc7ac \ud6c4 \ud64d\ubc18\uc774\ub098 \ubc1c\uc9c4\uc744 \ud3ec\ud568\ud55c \uc758\uc2ec\uc2a4\ub7ec\uc6b4 \ud53c\ubd80 \uc774\uc0c1 \ubc18\uc751\uc774 \ubc1c\uc0dd\ud55c \uacbd\uc6b0 \uc7a5\uce58 \uc0ac\uc6a9\uc744 \uc989\uc2dc \uc911\ub2e8\ud558\uace0 \ucc38\uac00\uc790\ub97c \uc2dc\ud5d8\uc5d0\uc11c \uc81c\uc678\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\ud608\uccad 25-\ud558\uc774\ub4dc\ub85d\uc2dc\ube44\ud0c0\ubbfc D \uce21\uc815<\/h3>\n

\ud608\uccad \ube44\ud0c0\ubbfc D \uc601\uc591 \uc0c1\ud0dc \uce21\uc815\uc5d0 \ub110\ub9ac \uc0ac\uc6a9\ub418\ub294 \ud608\uccad 25-\ud558\uc774\ub4dc\ub85d\uc2dc\ube44\ud0c0\ubbfc D[25(OH)D] \ub18d\ub3c4\ub97c \ud608\uccad \ube44\ud0c0\ubbfc D \uc601\uc591 \uc0c1\ud0dc\uc758 \uc9c0\ud45c\ub85c \ucc44\ud0dd\ud588\uc2b5\ub2c8\ub2e4.17<\/a>]. \ud608\uccad 25(OH)D \ub18d\ub3c4\ub294 \uace0\uc131\ub2a5 \uc561\uccb4 \ud06c\ub85c\ub9c8\ud1a0\uadf8\ub798\ud53c-\ud0e0\ub364-\uc9c8\ub7c9 \ubd84\uc11d\ubc95\uc744 \uc0ac\uc6a9\ud558\uc5ec \uce21\uc815\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ube44\ud0c0\ubbfcD\ub294 \uac04\uacfc \uc2e0\uc7a5\uc744 \ud1b5\ud574 \ub300\uc0ac\ub418\uba70, \uadf8 \ub300\uc0ac\ub294 \ud608\uccad \uce7c\uc298\uacfc \uc778\uc0b0\uc5fc\uacfc \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4.18<\/a>]. \ub530\ub77c\uc11c \uce7c\uc298, \uc778\uc0b0\uc5fc, \uc54c\ub77c\ub2cc \ud2b8\ub79c\uc2a4\uc544\ubbf8\ub098\uc81c, \uc544\uc2a4\ud30c\ub974\ud14c\uc774\ud2b8 \uc544\ubbf8\ub178\ud2b8\ub79c\uc2a4\ud37c\ub77c\uc81c, \uc54c\uce7c\ub9ac\uc131 \ud3ec\uc2a4\ud30c\ud0c0\uc81c, \uac10\ub9c8-\uae00\ub8e8\ud0c0\ubc00 \ud2b8\ub79c\uc2a4\ud3a9\ud2f0\ub2e4\uc81c, \ucd1d \ube4c\ub9ac\ub8e8\ube48, \ud06c\ub808\uc544\ud2f0\ub2cc \ubc0f \ud608\uc561 \uc694\uc18c \uc9c8\uc18c\uc758 \ud608\uccad \uc218\uc900\ub3c4 \ud608\uccad 25(OH)D \uce21\uc815\uacfc \ub3d9\uc2dc\uc5d0 \ud3c9\uac00\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ud608\uc561 \uac80\uc0ac\ub294 1\ucc28(\uae30\uc900), 3\ucc28(2\uc8fc), 4\ucc28(4\uc8fc), \ucd5c\uc885 \ubc29\ubb38 \ub4f1 4\ud68c \uc2e4\uc2dc\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ucd5c\uc885 \ubc29\ubb38\uc740 \uc911\uc7ac \uc885\ub8cc \ud6c4(6\uc8fc\ucc28) 2\uc8fc \ud6c4\uc5d0 \uc2e4\uc2dc\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ubaa8\ub4e0 \ud608\uc561\uac80\uccb4\ub294 \uae08\uc2dd\ud558\uc9c0 \uc54a\uc740 \uc0c1\ud0dc\uc5d0\uc11c \uc8fc\uac04(\uc624\uc804 9\uc2dc 30\ubd84\ubd80\ud130 \uc624\ud6c4 4\uc2dc\uae4c\uc9c0)\uc5d0 \ucc44\ucde8\ud558\uc5ec \uc801\uc808\ud558\uac8c \ucc98\ub9ac\ud558\uc5ec \uac80\uc0ac\uae30\uad00(\ub300\ud55c\ubbfc\uad6d \uc11c\uc6b8 \uc784\uc0c1\uc2e4\ud5d8\uc2e4)\uc73c\ub85c \uc774\uc1a1\ud558\uc600\uc2b5\ub2c8\ub2e4. . \ubaa8\ub4e0 \ud608\uc561 \uac80\uc0ac\ub294 \uac01 \ucc38\uac00\uc790\uc5d0 \ub300\ud574 \ud558\ub8e8 \uc911 \ub3d9\uc77c\ud55c \uc2dc\uac04\uc5d0 \uc218\ud589\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ub610\ud55c, \ucc38\uac00\uc790\uac00 \uc5f0\uad6c\uc5d0 \ucc38\uc5ec\ud55c \uacc4\uc808\uc740 \ud55c\uad6d \uc131\uc778 \uc778\uad6c\uc758 \ud608\uccad 25(OH)D \uc218\uce58\uc758 \uacc4\uc808\uc801 \ubcc0\ud654\ub85c \uc778\ud55c \uad50\ub780 \uc694\uc778\uc73c\ub85c \uac04\uc8fc\ub418\uc5c8\uc2b5\ub2c8\ub2e4.19<\/a>]. \uc5f0\uad6c \ucc38\uac00\uc790\ub294 \uc5f0\uad6c \ub4f1\ub85d \uacc4\uc808\uc5d0 \ub530\ub77c \ubd04(3~5\uc6d4), \uc5ec\ub984(6~8\uc6d4), \uac00\uc744(9~11\uc6d4), \uaca8\uc6b8(12~2\uc6d4)\uc758 \ub124 \uadf8\ub8f9\uc73c\ub85c \ubd84\ub958\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc778\uad6c\ud1b5\uacc4\ud559\uc801 \ud2b9\uc131<\/h3>\n

\uc5f0\ub839, \uc131\ubcc4, \uccb4\uc9c8\ub7c9\uc9c0\uc218, \uacb0\ud63c\uc0c1\ud0dc, \uad50\uc721\uc218\uc900, \ud604\uc7ac \ud761\uc5f0\uc0c1\ud0dc, \uc74c\uc8fc\uc2b5\uad00, \uc2e0\uccb4\ud65c\ub3d9 \uc218\uc900 \ub4f1\uc758 \uc778\uad6c\ud1b5\uacc4\ud559\uc801 \uc815\ubcf4\ub97c \uccab \ubc29\ubb38 \uc2dc \ud68d\ub4dd\ud558\uc600\ub2e4. \uc74c\uc8fc\uc2b5\uad00\uc740 \uc9c0\ub09c \ud55c \ub2ec \ub3d9\uc548 \ucd5c\uc18c 1\ud68c \uc774\uc0c1 \uc74c\uc8fc\ud55c \uacbd\uc6b0\ub97c \uae0d\uc815\uc801\uc778 \uac83\uc73c\ub85c \ubd84\ub958\ud558\uc600\ub2e4. \uc2e0\uccb4\ud65c\ub3d9 \uc218\uc900\uc740 \uc8fc 3\ud68c, 30\ubd84 \uc774\uc0c1 \uc6b4\ub3d9\uc744 \ud55c \uc0ac\ub78c\uc744 \uc591\uc131\uc73c\ub85c \ubd84\ub958\ud558\uc600\ub2e4.<\/p>\n

\uc601\uc591 \ubc0f \uc57c\uc678 \ud65c\ub3d9<\/h3>\n

\ud608\uccad 25(OH)D \uc218\uce58\ub294 \ud587\ube5b \ub178\ucd9c\uc774\ub098 \uc2dd\uc774 \ubcf4\ucda9\uc81c\ub97c \ud1b5\ud55c \ud53c\ubd80\uc758 \ube44\ud0c0\ubbfc D \uc0dd\uc131\uc5d0 \uc758\ud574 \uc601\ud5a5\uc744 \ubc1b\uc744 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c \uc6b0\ub9ac\ub294 \uc911\uc7ac 2\uc8fc, 4\uc8fc\uc640 \uc911\uc7ac \uc885\ub8cc \ud6c4 2\uc8fc\uc5d0 \uc77c\uc77c \uc2dd\uc774 \ube44\ud0c0\ubbfc D \uc12d\ucde8\ub7c9\uacfc \uc57c\uc678 \ud65c\ub3d9\uc5d0 \uc18c\ube44\ud55c \uc2dc\uac04\uc744 \uc870\uc0ac\ud588\uc2b5\ub2c8\ub2e4. \ubaa8\ub4e0 \ucc38\uac00\uc790\uc5d0\uac8c\ub294 \uc911\uc7ac \uae30\uac04 \uc804\uccb4 4\uc8fc \ub3d9\uc548\uacfc \uc911\uc7ac \uc885\ub8cc \ud6c4 \ucd94\uac00 2\uc8fc \ub3d9\uc548 \uc2dd\ub2e8\uacfc \uc57c\uc678 \ud65c\ub3d9 \uc218\uc900\uc5d0 \ub300\ud55c \uc77c\uc77c \uc77c\uae30\ub97c \uc791\uc131\ud558\ub3c4\ub85d \uc9c0\uc2dc\ud588\uc2b5\ub2c8\ub2e4. \ub610\ud55c \uc911\uc7ac \uc2dc\uc791\ubd80\ud130 \uac01 \ud3c9\uac00\uae4c\uc9c0 \uc77c\uc77c \ud3c9\uade0 \uc2dd\uc774 \ube44\ud0c0\ubbfc D \uc12d\ucde8\ub7c9\uacfc \uc57c\uc678 \ud65c\ub3d9\uc5d0 \uc18c\ube44\ud55c \uc2dc\uac04\uc744 \uacc4\uc0b0\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\ud1b5\uacc4 \ubd84\uc11d<\/h3>\n

\uc6b0\ub9ac\ub294 \uc2e0\ub8b0 \uc218\uc900 95%, \ud6a8\uacfc \ud06c\uae30 0.5, \ud1b5\uacc4 \uac80\uc815\ub825 0.8\uc5d0\uc11c G*Power \uc18c\ud504\ud2b8\uc6e8\uc5b4\ub97c \uc0ac\uc6a9\ud558\uc5ec 128\uba85\uc758 \ud53c\ud5d8\uc790(\uac01 \uadf8\ub8f9\ub2f9 64\uba85)\ub85c \ud544\uc694\ud55c \ucd5c\uc18c \ud45c\ubcf8 \ud06c\uae30\ub97c \uacc4\uc0b0\ud588\uc2b5\ub2c8\ub2e4. 0.5\uc758 \ud6a8\uacfc \ud06c\uae30\ub294 "\uc911\uac04" \ud6a8\uacfc \ud06c\uae30\ub97c \ub098\ud0c0\ub0b4\ubbc0\ub85c \ucc44\ud0dd\ub418\uc5c8\uc2b5\ub2c8\ub2e4. 15%\uc758 \ud0c8\ub77d\ub960\uc744 \uace0\ub824\ud558\uc5ec 150\uba85(\uadf8\ub8f9\ub2f9 75\uba85) \uc774\uc0c1\uc758 \ud53c\ud5d8\uc790\ub97c \ub4f1\ub85d\ud558\uae30\ub85c \uacb0\uc815\ud588\uc2b5\ub2c8\ub2e4. \ubcf8 \uc5f0\uad6c\uc5d0\uc11c\ub294 \ud0c8\ub77d\uc790\ub85c\ubd80\ud130 \ub370\uc774\ud130\ub97c \uc81c\uc678\ud55c \ud6c4 \ud504\ub85c\ud1a0\ucf5c\ubcc4(PP) \ubd84\uc11d\uc744 \uc2e4\uc2dc\ud558\uc600\ub2e4.<\/p>\n

\uc2e4\ud5d8\uad70\uacfc \ub300\uc870\uad70 \uac04\uc758 \uc5f0\uc18d \ubcc0\uc218\uc5d0 \ub300\ud574\uc11c\ub294 \ub3c5\ub9bd t-\uac80\uc815 \ub610\ub294 Mann Whitney U \uac80\uc815\uc744 \uc0ac\uc6a9\ud558\uace0 \ubc94\uc8fc\ud615 \ubcc0\uc218\uc5d0 \ub300\ud574\uc11c\ub294 \uce74\uc774\uc81c\uacf1 \uac80\uc815\uc744 \uc0ac\uc6a9\ud558\uc5ec \uae30\ubcf8 \uc778\uad6c\ud1b5\uacc4\ud559\uc801 \ud2b9\uc131\uc744 \ube44\uad50\ud588\uc2b5\ub2c8\ub2e4. \uac01 \ud608\uccad 25(OH)D \uc218\uc900 \ud3c9\uac00\uc5d0\uc11c \uae30\uc900\uc120\uc73c\ub85c\ubd80\ud130\uc758 \ubcc0\ud654\uc640 \uad00\ub828\ud558\uc5ec \ub300\uc751 t-\uac80\uc815 \ubc0f \ub3c5\ub9bd t-\uac80\uc815(\ub610\ub294 Mann Whitney) \uc720<\/i> \ud14c\uc2a4\ud2b8)\uc740 \uadf8\ub8f9 \ub0b4 \ucc28\uc774\uc640 \uadf8\ub8f9 \uac04 \ucc28\uc774\ub97c \uac01\uac01 \ud3c9\uac00\ud558\uae30 \uc704\ud574 \ucc44\ud0dd\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uac00\ub2a5\ud55c \uad50\ub780 \uc694\uc778\uc744 \ud1b5\uc81c\ud55c \ud6c4 \ud608\uccad 25(OH)D \uc218\uc900\uc758 \ubcc0\ud654\ub97c \ube44\uad50\ud558\uae30 \uc704\ud574 \uacf5\ubd84\uc0b0 \ubd84\uc11d\ub3c4 \uc218\ud589\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc2e4\ud5d8\uad70\uc758 \ud558\uc704 \ubd84\uc11d\uc73c\ub85c, \uae30\uc900 \ud3c9\uac00\uc5d0\uc11c \ube44\ud0c0\ubbfc D \uacb0\ud54d \uc720\ubb34\uc5d0 \ub530\ub978 \uc911\uc7ac 4\uc8fc \ud6c4 \ud608\uccad 25(OH)D \uc218\uc900\uc758 \ubcc0\ud654\ub97c \ube44\uad50\ud558\uae30 \uc704\ud574 \ub3c5\ub9bd\uc801\uc778 t-\uac80\uc815\uacfc ANCOVA\ub97c \uc0ac\uc6a9\ud588\uc2b5\ub2c8\ub2e4. \ube44\ud0c0\ubbfc D \uacb0\ud54d\uc740 \ud608\uccad 25(OH)D \uc218\uce58\uac00 20ng\/ml \ubbf8\ub9cc\uc778 \uacbd\uc6b0\ub85c \uc815\uc758\ub429\ub2c8\ub2e4.20<\/a>]. \ubaa8\ub4e0 \ud1b5\uacc4 \ubd84\uc11d\uc740 Windows\uc6a9 SPSS \ubc84\uc804 25.0(SPSS, Chicago, IL, USA)\uc744 \uc0ac\uc6a9\ud558\uc5ec \uc218\ud589\ub418\uc5c8\uc73c\uba70 \uc591\uce21 \ubd84\uc11d\uc740 \ud53c<\/i> 0.05 \ubbf8\ub9cc\uc758 \uac12\uc744 \ud1b5\uacc4\uc801\uc73c\ub85c \uc720\uc758\ud55c \uac83\uc73c\ub85c \uac04\uc8fc\ud558\uc600\ub2e4.<\/p>\n<\/div>\n

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