{"id":5171,"date":"2024-01-16T11:01:40","date_gmt":"2024-01-16T11:01:40","guid":{"rendered":"https:\/\/farlong.com\/?p=5171"},"modified":"2024-01-27T10:30:11","modified_gmt":"2024-01-27T10:30:11","slug":"research-progress-on-pyroptosis-mediated-immune-inflammatory-response-in-ischemic-stroke-and-the-role-of-natural-plant-components-as-regulator-of-pyroptosis-a-review","status":"publish","type":"post","link":"https:\/\/directcm.com\/ko\/research-progress-on-pyroptosis-mediated-immune-inflammatory-response-in-ischemic-stroke-and-the-role-of-natural-plant-components-as-regulator-of-pyroptosis-a-review\/","title":{"rendered":"\ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc5d0\uc11c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \ub9e4\uac1c \uba74\uc5ed \uc5fc\uc99d \ubc18\uc751\uacfc \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uc870\uc808\uc81c\ub85c\uc11c \ucc9c\uc5f0 \uc2dd\ubb3c \uc131\ubd84\uc758 \uc5ed\ud560\uc5d0 \ub300\ud55c \uc5f0\uad6c \uc9c4\ud589: \uac80\ud1a0"},"content":{"rendered":"<div id=\"ab0015\" class=\"abstract author-highlights\">\n<h2 class=\"section-title u-h4 u-margin-l-top u-margin-xs-bottom\">\ud558\uc774\ub77c\uc774\ud2b8<\/h2>\n<div id=\"abs0015\">\n<ul>\n<li id=\"p0005\">\uc774 \ub9ac\ubdf0\uc5d0\uc11c\ub294 \ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc5d0 \ub300\ud55c \ubc1c\uc5f4\uc99d\uc758 \ucd5c\uc2e0 \ubd84\uc790 \uba54\ucee4\ub2c8\uc998\uc744 \uc694\uc57d\ud588\uc2b5\ub2c8\ub2e4.<\/li>\n<li id=\"p0010\">\uc774 \ub9ac\ubdf0\ub294 \ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc5d0\uc11c \ubc1c\uc5f4\uc99d\uc758 \uc870\uc808\uc790\ub85c\uc11c \ucc9c\uc5f0 \uc2dd\ubb3c \uc131\ubd84\uc758 \uc5ed\ud560\uc744 \uc694\uc57d\ud569\ub2c8\ub2e4.<\/li>\n<li id=\"p0015\">\ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc5d0\uc11c \ubc1c\uc5f4\uc99d\uc758 \uc870\uc808\uc740 \uc7a0\uc7ac\uc801\uc778 \uce58\ub8cc \uc804\ub7b5\uc73c\ub85c \uc81c\uc548\ub429\ub2c8\ub2e4.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<div id=\"ab0010\" class=\"abstract author\"><\/p>\n<h2><\/h2>\n<h2 class=\"section-title u-h4 u-margin-l-top u-margin-xs-bottom\">\ucd94\uc0c1\uc801\uc778<\/h2>\n<div id=\"abs0010\">\n<p id=\"sp0030\"><a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/brain-ischemia\">\ud5c8\ud608\uc131 \ub1cc\uc878\uc911<\/a>\u00a0(IS)\ub294 \uc0ac\ub9dd \ubc0f \uc7a5\uc560\uc758 \uc8fc\uc694 \uc6d0\uc778 \uc911 \ud558\ub098\uc785\ub2c8\ub2e4. \ubc1c\ubcd1\uae30\uc804\uc740 \uc644\uc804\ud788 \uba85\ud655\ud558\uc9c0 \uc54a\uc73c\uba70, \uc5fc\uc99d\uc131 \uc5f0\uc1c4\ubc18\uc751\uc774 \uc8fc\uc694 \uc6d0\uc778 \uc911 \ud558\ub098\uc785\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ubcd1\ub9ac\ud559\uc801 \uacfc\uc815\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/pathological-process\">\ubcd1\ub9ac\ud559\uc801 \uacfc\uc815<\/a>. IS\uc758 \ud604\uc7ac \uc784\uc0c1 \uc2e4\uc2b5\uc740\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud608\uc561 \uacf5\uae09\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/vascularity\">\ud608\uc561 \uacf5\uae09<\/a>\u00a0IS \ud6c4 \uac00\ub2a5\ud55c \ud55c \ube68\ub9ac \ud5c8\ud608\uc131 \ubd80\uc704\ub85c\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud608\uc804\uc6a9\ud574 \uc694\ubc95\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/fibrinolytic-therapy\">\ud608\uc804\uc6a9\ud574\uc694\ubc95<\/a>\u00a0\ub274\ub7f0\uc758 \ud65c\ub825\uacfc \uae30\ub2a5\uc744 \ubcf4\ud638\ud569\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \ud608\uc561 \uc7ac\uad00\ub958\ub294 \ud5c8\ud608\uc131 \uc190\uc0c1\uc744 \ub354\uc6b1 \uac00\uc18d\ud654\ud558\uace0 \ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc744 \uc720\ubc1c\ud569\ub2c8\ub2e4. \ub1cc\ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc758 \ubcd1\ub9ac\ud559\uc801 \uacfc\uc815\uc740 \ub2e4\uc591\ud55c \uae30\uc804\uc744 \uc218\ubc18\ud558\uba70, \uc815\ud655\ud55c \uae30\uc804\uc740 \uc644\uc804\ud788 \ubc1d\ud600\uc9c0\uc9c0 \uc54a\uc558\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc5f4\ubd84\ud574\uc99d\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/pyroptosis\">\ubc1c\uc5f4\uc99d<\/a>, \uc0c8\ub85c \ubc1c\uacac\ub41c \uc5fc\uc99d\uc131 \ud615\ud0dc\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud504\ub85c\uadf8\ub7a8\ub41c \uc138\ud3ec \uc0ac\uba78\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/programmed-cell-death\">\ud504\ub85c\uadf8\ub7a8\ub41c \uc138\ud3ec \uc0ac\uba78<\/a>, \uc5fc\uc99d\uc758 \uc2dc\uc791\uacfc \uc9c4\ud589\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \uc774\ub294 \ub2e4\uc74c\uc744 \ub9e4\uac1c\ub85c \ud558\ub294 \uc804\uc5fc\uc99d\uc131 \ud504\ub85c\uadf8\ub7a8 \uc0ac\ub9dd\uc785\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uce74\uc2a4\ud30c\uc81c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/caspase\">\uce74\uc2a4\ud30c\uc81c<\/a>\u00a0\uc138\ud3ec \ubd80\uc885 \ubc0f \ud30c\uc5f4\uc744 \uc720\ubc1c\ud560 \uc218 \uc788\ub294 \uce74\uc2a4\ud30c\uc81c-1\/4\/5\/11\uc740 \uc5fc\uc99d \uc778\uc790 IL-1\u03b2 \ubc0f IL-18\uc744 \ubc29\ucd9c\ud558\uace0 \uc5fc\uc99d \uc5f0\uc1c4\ubc18\uc751\uc744 \uc720\ub3c4\ud569\ub2c8\ub2e4. \ucd5c\uadfc \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc640 \uadf8\uc5d0 \ub530\ub978 \uc5fc\uc99d \ubc18\uc751\uc740 \ud5c8\ud608\uc131 \ub1cc \uc190\uc0c1\uc744 \uc545\ud654\uc2dc\ud0a4\ub294 \uc911\uc694\ud55c \uc694\uc778\uc774\uba70, \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc5b5\uc81c\ud558\uba74 \ud5c8\ud608\uc131 \ub1cc \uc190\uc0c1\uc744 \uc644\ud654\ud560 \uc218 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \ub610\ud55c, \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \ucc9c\uc5f0 \uc2dd\ubb3c \uc131\ubd84\uc774 \ubc1c\uc5f4\uc99d\uc5d0 \uaddc\uc81c \ud6a8\uacfc\uac00 \uc788\uc744 \uc218 \uc788\ub2e4\ub294 \uc0ac\uc2e4\uc774 \ubc1d\ud600\uc84c\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c \ubcf8 \ub9ac\ubdf0\uc5d0\uc11c\ub294 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc758 \ubd84\uc790 \uba54\ucee4\ub2c8\uc998\uacfc \ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc5d0\uc11c\uc758 \uadf8 \uc5ed\ud560\uc744 \uc694\uc57d\ud560 \ubfd0\ub9cc \uc544\ub2c8\ub77c, \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc5d0 \ub300\ud55c \ucc38\uace0 \uc815\ubcf4\ub97c \uc81c\uacf5\ud558\uae30 \uc704\ud574 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc758 \uc870\uc808\uc790\ub85c\uc11c \ucc9c\uc5f0 \uc2dd\ubb3c \uc131\ubd84\uc758 \uc5ed\ud560\ub3c4 \uc694\uc57d\ud569\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uce58\ub8cc\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/therapeutic-procedure\">\uce58\ub8cc<\/a>\u00a0\ubbf8\ub798\uc5d0\ub294 IS\uc758.<\/p>\n<div class=\"Keywords u-font-serif text-s\">\n<div id=\"keys0005\" class=\"keywords-section\">\n<h2 class=\"section-title u-h4 u-margin-l-top u-margin-xs-bottom\">\ud0a4\uc6cc\ub4dc<\/h2>\n<div id=\"key0005\" class=\"keyword\">\uc5f4\ubd84\ud574\uc99d; \ud5c8\ud608\uc131 \ub1cc\uc878\uc911; \uce74\uc2a4\ud30c\uc81c; \ucc9c\uc5f0 \uc2dd\ubb3c \uc131\ubd84; \uc5fc\uc99d\ubcf5\ud569\uccb4<\/div>\n<\/div>\n<\/div>\n<div id=\"body\" class=\"Body u-font-serif text-s\">\n<div>\n<section id=\"sec0005\">\n<h2 id=\"sect0025\" class=\"u-h4 u-margin-l-top u-margin-xs-bottom\">1. \uc18c\uac1c<\/h2>\n<p id=\"p0025\">\uc138\uacc4 \uc778\uad6c\uc758 \ub178\ub839\ud654\ub85c \uc778\ud574 \ubc1c\ubcd1\ub960\uc774 \uc99d\uac00\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub1cc\ud608\uad00 \uc9c8\ud658\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/cerebrovascular-disease\">\ub1cc\ud608\uad00 \uc9c8\ud658<\/a>\u00a0(\ub1cc\uc878\uc911 \ub4f1)\uc740 \uc138\uacc4\uc5d0\uc11c \ub450 \ubc88\uc9f8\ub85c \ud070 \uaddc\ubaa8\uac00 \ub418\uc5c8\uc73c\uba70, \uc778\ub958\uc5d0 \ub300\ud55c \uc704\ud611\uc740 \uc99d\uac00\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib1\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib1\"><span class=\"anchor-text\">[1]<\/span><\/a>. \ub1cc\uc878\uc911\uc5d0\ub294 \ub2e4\uc74c\uc774 \ud3ec\ud568\ub429\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/brain-ischemia\">\ud5c8\ud608\uc131 \ub1cc\uc878\uc911<\/a>\u00a0(IS) \ubc0f\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ucd9c\ud608\uc131 \ub1cc\uc878\uc911\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/cerebral-hemorrhage\">\ucd9c\ud608\uc131 \ub1cc\uc878\uc911<\/a>, \ucd5c\ub300 87%\uc758 \ub1cc\uc878\uc911\uc774 \ud5c8\ud608\uc131\uc785\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib2\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib2\"><span class=\"anchor-text\">[2]<\/span><\/a>. IS\ub294 \uc77c\ubc18\uc801\uc778 \uc784\uc0c1\uc801 \uc751\uae09 \uc0c1\ud669\uc774\uba70 \uadf8 \ubc1c\uc0dd\ub960\uc740 \ud574\ub9c8\ub2e4 \uc99d\uac00\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. IS\uc758 \ud604\uc7ac \uc784\uc0c1 \uc2e4\uc2b5\uc740\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud608\uc561 \uacf5\uae09\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/vascularity\">\ud608\uc561 \uacf5\uae09<\/a>\u00a0IS \ud6c4 \uac00\ub2a5\ud55c \ud55c \ube68\ub9ac \ud5c8\ud608\uc131 \ubd80\uc704\ub85c\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud608\uc804\uc6a9\ud574 \uc694\ubc95\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/fibrinolytic-therapy\">\ud608\uc804\uc6a9\ud574\uc694\ubc95<\/a>\u00a0\ub274\ub7f0\uc758 \ud65c\ub825\uacfc \uae30\ub2a5\uc744 \ubcf4\ud638\ud558\uae30 \uc704\ud574\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib3\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib3\"><span class=\"anchor-text\">[3]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib4\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib4\"><span class=\"anchor-text\">[4]<\/span><\/a>. \uadf8\ub7ec\ub098 \ud608\ub958 \ud68c\ubcf5 \ud6c4 \ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1(IRI)\uc740 \uc885\uc885 \ub2e4\uc74c\uacfc \uac19\uc740 \ub354 \uc2ec\uac01\ud55c \uc190\uc0c1\uc744 \ucd08\ub798\ud569\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub1cc \uc870\uc9c1\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/brain-tissue\">\ub1cc \uc870\uc9c1<\/a>\u00a0\ub354\uc6b1\uc774 \ud658\uc790\uc758 \uc608\ud6c4 \ubd88\ub7c9 \ubc0f \uae30\ub2a5 \uc7a5\uc560\ub97c \ucd08\ub798\ud558\ub294 \uc911\uc694\ud55c \uc694\uc778\uc774 \ub429\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib5\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib5\"><span class=\"anchor-text\">[5]<\/span><\/a>. \uc804 \uc138\uacc4 \uc5ed\ud559\uc870\uc0ac\ub294 1990\ub144\ubd80\ud130 2019\ub144\uae4c\uc9c0 \uc804 \uc138\uacc4 204\uac1c \uad6d\uac00\uc640 \uc9c0\uc5ed\uc758 \ub370\uc774\ud130\ub97c \ubd84\uc11d\ud588\ub2e4. \ubcf4\uace0\uc11c\uc5d0 \ub530\ub974\uba74 \ub1cc\uc878\uc911\uc740 \uc5ec\uc804\ud788 \uc0ac\ub9dd \uc6d0\uc778 2\uc704(\ucd1d \uc0ac\ub9dd \uc6d0\uc778 11.6%), \uc0ac\ub9dd \ubc0f \uc7a5\uc560 \uc6d0\uc778 3\uc704(\uc804\uccb4 \uc0ac\ub9dd \uc6d0\uc778 5.7%)\uc785\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc7a5\uc560 \uc870\uc815 \uc218\uba85\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/disability-adjusted-life-years\">\uc7a5\uc560 \uc870\uc815 \uc218\uba85<\/a>\u00a0(DALYs)]\uc5d0 \uc774\uc5b4 \ub450 \ubc88\uc9f8\uc785\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc2e0\uc0dd\uc544 \uc9c8\ud658\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/newborn-disease\">\uc2e0\uc0dd\uc544 \uc9c8\ud658<\/a>\u00a0(7.3% DALY) \ubc0f\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud5c8\ud608\uc131 \uc2ec\uc7a5 \uc9c8\ud658\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/ischemic-heart-disease\">\ud5c8\ud608\uc131 \uc2ec\uc7a5 \uc9c8\ud658<\/a>\u00a0(7.2% DALYs), \ub1cc\uc878\uc911 \ud658\uc790 \uc218\ub294 \uc5ec\uc804\ud788 \uc99d\uac00\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib6\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib6\"><span class=\"anchor-text\">[6]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib7\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib7\"><span class=\"anchor-text\">[7]<\/span><\/a>, \ud2b9\ud788 \uc911\uad6d\uc5d0\uc11c\ub294\uc694. \uc911\uad6d\uc740 \uc138\uacc4\uc5d0\uc11c \ub1cc\uc878\uc911 \uc704\ud5d8\uc774 \uac00\uc7a5 \ub192\uc740 \uad6d\uac00\uac00 \ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc8fc\ubbfc\uc758 \ub1cc\uc878\uc911 \uc704\ud5d8\uc740 39.3%\uc5d0 \ub3c4\ub2ec\ud588\uc73c\uba70, \uc911\uad6d \ub0a8\uc131\uc758 \ub1cc\uc878\uc911 \uc704\ud5d8\ub3c4 41%\ub97c \ucd08\uacfc\ud558\uc5ec \uc138\uacc4\uc5d0\uc11c \uac00\uc7a5 \ub192\uc2b5\ub2c8\ub2e4. IS\ub294 \uc911\uad6d\uc778 \uc0ac\ub9dd \uc6d0\uc778 3\uc704(1990\ub144 \uae30\uc900)\uc5d0\uc11c 2017\ub144 \uae30\uc900 1\uc704(2017\ub144 \uae30\uc900)\ub85c \uc0c1\uc2b9\ud588\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib8\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib8\"><span class=\"anchor-text\">[8]<\/span><\/a>. \ud604\uc7ac \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \ub300\ub1cc IRI(CIRI)\uc758 \ubcd1\ub9ac\ud559\uc801 \uba54\ucee4\ub2c8\uc998\uc740 \uc8fc\ub85c \ub2e4\uc74c\uacfc \uac19\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/oxidative-stress\">\uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4<\/a>\u00a0\ubd80\uc0c1,\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc5fc\uc99d\uc131 \uc190\uc0c1\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/inflammatory-injury\">\uc5fc\uc99d\uc131 \uc190\uc0c1<\/a>, \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc190\uc0c1, \uc790\uac00\ud3ec\uc2dd \ubc0f\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc138\ud3ec\uc0ac\uba78\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/programmed-cell-death\">\uc138\ud3ec\uc0ac\uba78<\/a>\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib9\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib9\"><span class=\"anchor-text\">[9]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib10\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib10\"><span class=\"anchor-text\">[10]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib11\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib11\"><span class=\"anchor-text\">[11]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib12\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib12\"><span class=\"anchor-text\">[12]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib13\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib13\"><span class=\"anchor-text\">[13]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib14\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib14\"><span class=\"anchor-text\">[14]<\/span><\/a>. \uadf8\ub7ec\ub098 \uc774\ub7ec\ud55c \uac83\ub4e4\uc740 \uc9c8\ubcd1\uc758 \ubcd1\ub9ac\ud559\uc801 \uae30\uc804\uc744 \uc124\uba85\ud558\uae30\uc5d0\ub294 \uc544\uc9c1 \ubd88\ucda9\ubd84\ud558\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c CIRI\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/immunoreactive-insulin\">CIRI<\/a>. \uc608\ub97c \ub4e4\uc5b4 CIRI \uc774\ud6c4\uc758 \uc2e0\uacbd\uc138\ud3ec \uc0ac\uba78\uc740 \uc8fc\ub85c \uc138\ud3ec\uc0ac\uba78(apoptosis)\uc5d0 \uc758\ud574 \ubc1c\uc0dd\ud558\ub294 \uac83\uc73c\ub85c \uc0dd\uac01\ub418\uba70, \uc2e0\uacbd\uc138\ud3ec \ubcf4\ud638 \ubc29\ud5a5\uc740 \uc8fc\ub85c \ud56d\uc138\ud3ec\uc0ac\uba78(anti-apoptosis)\uc774\ub2e4. \uadf8\ub7ec\ub098 \uc138\ud3ec\uc0ac\uba78\uc740 \uc5fc\uc99d\uacfc \uc9c1\uc811\uc801\uc778 \uad00\ub828\uc774 \uc5c6\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib15\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib15\"><span class=\"anchor-text\">[15]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib16\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib16\"><span class=\"anchor-text\">[16]<\/span><\/a>, \uadf8\ub7ec\ub098 CIRI\uc5d0\ub294 \uc0c1\ub2f9\ud55c \uc5fc\uc99d \ubc18\uc751\uc774 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib16\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib16\"><span class=\"anchor-text\">[16]<\/span><\/a>. \ub530\ub77c\uc11c IS\uc758 \ubcd1\ud0dc\uc0dd\ub9ac\ud559\uc801 \uae30\uc804\uc744 \ub354\uc6b1 \uba85\ud655\ud788 \ud558\uace0 CIRI\uc758 \ubcd1\uc778\uc744 \ub354\uc6b1 \ud0d0\uad6c\ud560 \ud544\uc694\uac00 \uc788\ub2e4.<\/p>\n<p id=\"p0030\"><a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc5f4\ubd84\ud574\uc99d\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/pyroptosis\">\ubc1c\uc5f4\uc99d<\/a>, \ub610\ud55c ~\uc73c\ub85c \uc54c\ub824\uc9c4\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc138\ud3ec \uc5fc\uc99d\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/inflammatory-cell\">\uc138\ud3ec \uc5fc\uc99d\uc131<\/a>\u00a0\uad34\uc0ac\ub294 \ucd5c\uadfc \uba87 \ub144 \ub3d9\uc548 \uc0c8\ub85c \ubc1c\uacac\ub418\uace0 \ud655\uc778\ub41c \ud504\ub85c\uadf8\ub7a8\ud654\ub41c \uc138\ud3ec \uc0ac\uba78\uc785\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib17\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib17\"><span class=\"anchor-text\">[17]<\/span><\/a>. Pyroptosis\ub294 \uc5fc\uc99d\uc5d0 \uc758\uc874\ud569\ub2c8\ub2e4\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uce74\uc2a4\ud30c\uc81c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/caspase\">\uce74\uc2a4\ud30c\uc81c<\/a>\u00a0(\uc8fc\ub85c \uce74\uc2a4\ud30c\uc81c-1, 4, 5, 11)\uc774\uba70 \ub2e4\uc218\uc758 \uc5fc\uc99d \uc720\ubc1c \uc778\uc790\uc758 \ubc29\ucd9c\uc744 \ub3d9\ubc18\ud569\ub2c8\ub2e4. \uc138\ud3ec\uac00 \uc131\uc7a5\ud560 \ub54c\uae4c\uc9c0 \uc138\ud3ec\uac00 \uc9c0\uc18d\uc801\uc73c\ub85c \ud33d\ucc3d\ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0a9\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub9c9 \ud30c\uc5f4\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/membrane-rupture\">\ub9c9 \ud30c\uc5f4<\/a>, \uacb0\uacfc\uc801\uc73c\ub85c \uc138\ud3ec \ub0b4\uc6a9\ubb3c\uc774 \ubc29\ucd9c\ub418\uace0 \uac15\ub825\ud55c \uc5fc\uc99d \ubc18\uc751\uc774 \ud65c\uc131\ud654\ub429\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib17\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib17\"><span class=\"anchor-text\">[17]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib18\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib18\"><span class=\"anchor-text\">[18]<\/span><\/a>. \uadf8\ub9cc\ud07c\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud615\ud0dc\ud559\uc801 \ud2b9\uc131\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/morphological-trait\">\ud615\ud0dc\ud559\uc801 \ud2b9\uc9d5<\/a>, pyroptosis\uc758 \ubc1c\uc0dd \ubc0f \uc870\uc808 \uba54\ucee4\ub2c8\uc998\uc740 apoptosis \ubc0f necrosis\uc640 \uac19\uc740 \ub2e4\ub978 \uc138\ud3ec \uc0ac\uba78 \ubc29\ubc95\uacfc \ub2e4\ub985\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib18\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib18\"><span class=\"anchor-text\">[18]<\/span><\/a>. \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub294 \uac10\uc5fc\uc131 \uc9c8\ud658, \uc2e0\uacbd\uacc4 \uad00\ub828 \uc9c8\ud658, \uc8fd\uc0c1\ub3d9\ub9e5\uacbd\ud654\uc131 \uc9c8\ud658, \uc545\uc131\uc885\uc591 \ub4f1 \ub2e4\uc591\ud55c \uc9c8\ubcd1\uc758 \ubc1c\uc0dd \ubc0f \ubc1c\ub2ec\uc5d0 \ud3ed\ub113\uac8c \uad00\uc5ec\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib19\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib19\"><span class=\"anchor-text\">[19]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib20\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib20\"><span class=\"anchor-text\">[20]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib21\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib21\"><span class=\"anchor-text\">[21]<\/span><\/a>. \ucd5c\uadfc \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4(pyroptosis)\uc640 \uadf8\uc5d0 \ub530\ub978 \ub9e4\uac1c \uc5fc\uc99d \ubc18\uc751\uc774\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ubcd1\ub9ac\ud559\uc801 \uacfc\uc815\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/pathological-process\">\ubcd1\ub9ac\ud559\uc801 \uacfc\uc815<\/a>\u00a0IS\uc758 \ud65c\uc131\uc744 \uc608\ubc29\ud558\uace0, \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc758 \ud65c\uc131\ud654\ub97c \uc608\ubc29\ud558\ub294 \uac83\uc740 \uc5fc\uc99d\uc131 \uc5f0\uc1c4\ubc18\uc751\uc744 \uc5b5\uc81c\ud558\uace0 \ud5c8\ud608\uc131 \ub1cc\uc190\uc0c1\uc744 \uc904\uc774\ub294 \ub370 \uc720\uc775\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib22\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib22\"><span class=\"anchor-text\">[22]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib23\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib23\"><span class=\"anchor-text\">[23]<\/span><\/a>. \uc774\ub97c \ubc14\ud0d5\uc73c\ub85c pyroptosis\uc5d0 \ub300\ud55c \uc5f0\uad6c\uac00 \ub9e4\uc6b0 \uc911\uc694\ud569\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uce58\ub8cc\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/therapeutic-procedure\">\uce58\ub8cc<\/a>\u00a0IS\uc758; \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc870\uc808\ud558\uba74 IS\uc758 \uce58\uc0ac\uc728\uc744 \ub0ae\ucd94\uace0 \ub274\ub7f0\uc758 \uc0dd\uc874\uc728\uc744 \ud5a5\uc0c1\uc2dc\ud0a4\uba70 IS \ud658\uc790\uc758 \uc99d\uc0c1\uc744 \ud638\uc804\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ud604\uc7ac,\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc57d\ubb3c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/chemotherapeutic-agent\">\uc57d\uc81c<\/a>\u00a0\ubc1c\ud718\ud558\ub294\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc2e0\uacbd\ubcf4\ud638\uc81c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/neuroprotective-agent\">\uc2e0\uacbd\ubcf4\ud638<\/a>\u00a0pyroptosis \uacbd\ub85c\ub97c \uc870\uc808\ud568\uc73c\ub85c\uc368 \ud6a8\uacfc\uac00 \uac1c\ubc1c\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ud2b9\ud788, IS\uc5d0\uc11c \ud608\uad00 \uc2e0\uacbd \ub2e8\uc704\uc758 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc870\uc808\ud558\ub294 \ucc9c\uc5f0 \uc2dd\ubb3c \uc131\ubd84\uc5d0 \ub300\ud55c \ub9ce\uc740 \uc5f0\uad6c\uac00 \uc788\uc2b5\ub2c8\ub2e4. \uc6b0\ub9ac\uc758 \uc774\uc804 \uc5f0\uad6c\uc5d0\uc11c\ub3c4 \ub2e4\uc74c\uacfc \uac19\uc740 \uc0ac\uc2e4\uc774 \ubc1d\ud600\uc84c\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc0ac\ud3ec\ub2cc\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/saponin\">\uc0ac\ud3ec\ub2cc<\/a>\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib24\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib24\"><span class=\"anchor-text\">[24]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib25\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib25\"><span class=\"anchor-text\">[25]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib26\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib26\"><span class=\"anchor-text\">[26]<\/span><\/a>\u00a0\ubc0f \ub2e4\uc131\ubd84 \ud654\ud569\ubb3c\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib27\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib27\"><span class=\"anchor-text\">[27]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib28\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib28\"><span class=\"anchor-text\">[28]<\/span><\/a>\u00a0\uc744 \uc870\uc808\ud560 \uc218 \uc788\ub2e4\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc0dd\ubb3c\ud559\uc801 \uacfc\uc815\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/biological-phenomena-and-functions-concerning-the-entire-organism\">\uc0dd\ubb3c\ud559\uc801 \uacfc\uc815<\/a>\u00a0IS\uc758 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4. \ub530\ub77c\uc11c \ubcf8 \ub9ac\ubdf0\uc5d0\uc11c\ub294 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc758 \ubd84\uc790 \uba54\ucee4\ub2c8\uc998\uacfc \ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc5d0\uc11c\uc758 \uadf8 \uc5ed\ud560\uc744 \uc694\uc57d\ud560 \ubfd0\ub9cc \uc544\ub2c8\ub77c, \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uc870\uc808\uc81c\ub85c\uc11c \ucc9c\uc5f0 \uc2dd\ubb3c \uc131\ubd84\uc758 \uc5ed\ud560\uc744 \uc694\uc57d\ud558\uc5ec \ud5a5\ud6c4 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uad00\ub828 \uc57d\ubb3c \uac1c\ubc1c\uc744 \uc704\ud55c \ub0a9 \ud654\ud569\ubb3c \ub610\ub294 \ucc9c\uc5f0 \uc2dd\ubb3c \uc131\ubd84\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4.<\/p>\n<\/section>\n<section id=\"sec0010\">\n<h2 id=\"sect0030\" class=\"u-h4 u-margin-l-top u-margin-xs-bottom\">2. \uc5f4\ubd84\ud574\uc99d<\/h2>\n<section id=\"sec0015\">\n<h3 id=\"sect0035\" class=\"u-h4 u-margin-m-top u-margin-xs-bottom\">2.1. \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc758 \ud2b9\uc9d5<\/h3>\n<div>\n<p id=\"p0035\"><a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc5f4\ubd84\ud574\uc99d\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/pyroptosis\">\ubc1c\uc5f4\uc99d<\/a>\u00a0\uc758 \ud615\ud0dc\uc774\ub2e4\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud504\ub85c\uadf8\ub7a8\ub41c \uc138\ud3ec \uc0ac\uba78\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/programmed-cell-death\">\ud504\ub85c\uadf8\ub7a8\ub41c \uc138\ud3ec \uc0ac\uba78<\/a>\u00a0\uc5fc\uc99d \uc720\ubc1c \ubb3c\uc9c8\uc5d0 \uc758\uc874\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uce74\uc2a4\ud30c\uc81c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/caspase\">\uce74\uc2a4\ud30c\uc81c<\/a>\uc774\ub294 \ub9c9\uad00\ud1b5 \uacf5\uadf9\uc758 \ud615\uc131, \uc138\ud3ec\ub9c9\uc758 \ubd80\uc885 \ubc0f \ud30c\uc5f4, \uc5fc\uc99d \uc720\ubc1c \ubb3c\uc9c8\uc758 \ubc29\ucd9c\uc744 \ud2b9\uc9d5\uc73c\ub85c \ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib29\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib29\"><span class=\"anchor-text\">[29]<\/span><\/a>. \uc138\ud3ec\uc0ac\uba78 \uacfc\uc815\uc5d0\uc11c \uc138\ud3ec\ub294 \uc8fc\ubcc0 \uc870\uc9c1\uc5d0 \uc5fc\uc99d \ubc18\uc751\uc744 \uc77c\uc73c\ud0a4\uc9c0 \uc54a\ub294 \ud575 \ub2e8\ud3b8\ud654 \ubc0f \uc138\ud3ec\ub9c9 \uc644\uc804\uc131\uc744 \uac16\ub294 \ubc18\uba74, \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uacfc\uc815\uc758 \uc138\ud3ec\ub294 \uc644\uc804\ud55c \ud575 \ud615\ud0dc\uc640 \uc138\ud3ec\ub97c \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub9c9 \ud30c\uc5f4\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/membrane-rupture\">\ub9c9 \ud30c\uc5f4<\/a>, \uc774\ub294 \ub9d0\ucd08 \uc5fc\uc99d\uc744 \uc720\ubc1c\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib30\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib30\"><span class=\"anchor-text\">[30]<\/span><\/a>. \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uac00 \ubc1c\uc0dd\ud558\uba74 \uc138\ud3ec\ub9c9\uc774 \uc810\ucc28 \ud30c\uc5f4\ub418\uc5b4 1~2nm\uc758 \uc138\ud3ec\ub9c9 \uacf5\uadf9\uc774 \ud615\uc131\ub418\uace0, \uc774\ud6c4 \uc138\ud3ec\ub0b4 \uc5fc\uc99d\uc778\uc790 \ubc0f \uae30\ud0c0 \ubb3c\uc9c8\uacfc \uac19\uc740 \uc138\ud3ec \ub0b4\uc6a9\ubb3c\uc774 \uc138\ud3ec\ub9c9 \uc678\ubd80\ub85c \ubc29\ucd9c\ub429\ub2c8\ub2e4. \ub2e4\uc74c\uacfc \uac19\uc740 \ub9c9 \ud22c\uacfc\uc131 \uc5fc\ub8cc\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc5d0\ud2f0\ub4d0 \ube0c\ub85c\ub9c8\uc774\ub4dc\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/ethidium-bromide\">\uc5d0\ud2f0\ub4d0 \ube0c\ub85c\ub9c8\uc774\ub4dc<\/a>\u00a0\uc138\ud3ec\uac00 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uacaa\ub294\uc9c0 \uc5ec\ubd80\ub97c \uad00\ucc30\ud558\ub294 \ub370 \uc0ac\uc6a9\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib31\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib31\"><span class=\"anchor-text\">[31]<\/span><\/a>. \ub610\ud55c \uad34\uc0ac\uc758 \ubc1c\uc0dd\uc740 \ud63c\ud569\ub41c \uacc4\uc5f4\uc758 \ub2e8\ubc31\uc9c8 \ud0a4\ub098\uc544\uc81c \uc720\uc0ac\uc5d0 \ub530\ub77c \ub2ec\ub77c\uc9d1\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub3c4\uba54\uc778 \ub2e8\ubc31\uc9c8\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/protein-domain\">\ub3c4\uba54\uc778 \ub2e8\ubc31\uc9c8<\/a>\u00a0(MLKL)\uc740 \uc138\ud3ec\ub85c \ub4e4\uc5b4\uac00\ub294 \uc774\uc628\uc5d0 \ub300\ud574 \uc120\ud0dd\uc801\uc774\uba70, \ud575 \uc5fc\uc0c9\uc9c8\uc740 \uc751\uc9d1\uc131\uc774 \uc788\uac70\ub098 \uac00\uc7a5\uc790\ub9ac\uc5d0 \ub369\uc5b4\ub9ac\uc838 \uc788\uc2b5\ub2c8\ub2e4. \uc5f4\ubd84\ud574\uc99d\uc740 \ud575\uc744 \uc720\ubc1c\ud558\ub294 \ube44\uc120\ud0dd\uc801 \ub2e8\ubc31\uc9c8\uc778 \uae30\uacf5 \ud615\uc131 \ub2e8\ubc31\uc9c8 GSDMD\uc5d0 \uc758\uc874\ud569\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ubc1c\uc5f4\uc99d\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/pyknosis\">\ubc1c\uc5f4\uc99d<\/a>\u00a0\uadf8\ub9ac\uace0\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c DNA \ub2e8\ud3b8\ud654\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/dna-fragmentation\">DNA \ub2e8\ud3b8\ud654<\/a>\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib32\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib32\"><span class=\"anchor-text\">[32]<\/span><\/a>. pyroptosis, apoptosis, necroptosis \ubc0f \uc0ac\uc774\uc5d0\ub294 \uc720\uc0ac\uc810\uacfc \ucc28\uc774\uc810\uc774 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud398\ub86d\ud1a0\uc2dc\uc2a4\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/ferroptosis\">\ud398\ub86d\ud1a0\uc99d<\/a>, \uc6d0\uc778, \uc140 \ubcc0\uacbd \ub4f1 \uc790\uc138\ud55c \ub0b4\uc6a9\uc740\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#tbl0005\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"tbl0005\"><span class=\"anchor-text\">1 \ubc88 \ud14c\uc774\ube14<\/span><\/a>.<\/p>\n<div id=\"tbl0005\" class=\"tables colsep-0 rowsep-0 frame-topbot\">\n<p id=\"sp0020\"><span class=\"label\">1 \ubc88 \ud14c\uc774\ube14<\/span>. pyroptosis, apoptosis \ubc0f necroptosis\uc758 \uc720\uc0ac\uc810\uacfc \ucc28\uc774\uc810.<\/p>\n<div class=\"groups\">\n<table>\n<thead>\n<tr class=\"rowsep-1\">\n<th scope=\"col\">\ud615\uc9c8<\/th>\n<th scope=\"col\">\uc2dc\uadf8\ub2c8\ucc98 \uad6c\uc131 \uc694\uc18c<\/th>\n<th scope=\"col\">\uc138\ud3ec\uc758 \ubcc0\ud654<\/th>\n<th scope=\"col\">\uc77c\ubc18\uc801\uc778 \uc6d0\uc778<\/th>\n<th scope=\"col\">\uc5b5\uc81c\uc81c<\/th>\n<th scope=\"col\">\ucc38\uc870<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<th scope=\"row\">\ubc1c\uc5f4\uc99d<\/th>\n<td>\ud30c\uc774\ub86d\ud1a0\uc19c, \uc778\ud50c\ub77c\ub9c8\uc19c<\/td>\n<td>\uae30\uacf5 \ud615\uc131, \uc138\ud3ec \ubd80\uc885, \uc6d0\ud615\uc9c8\ub9c9 \ud30c\uc5f4, \uc5fc\uc0c9\uc9c8 \uc751\ucd95, DNA \ub2e8\ud3b8\ud654, \ud575 \uc644\uc804\uc131 \ub4f1<\/td>\n<td>DAMP, PAMP, \uac10\uc5fc<\/td>\n<td>GSDMD \uc5b5\uc81c\uc81c<\/td>\n<td><a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib19\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib19\"><span class=\"anchor-text\">[19]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib33\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib33\"><span class=\"anchor-text\">[33]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib34\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib34\"><span class=\"anchor-text\">[34]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib35\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib35\"><span class=\"anchor-text\">[35]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib36\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib36\"><span class=\"anchor-text\">[36]<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\uc138\ud3ec\uc0ac\uba78<\/th>\n<td>\uc544\ud3fd\ud1a0\uc19c<\/td>\n<td>\uc190\uc0c1\ub418\uc9c0 \uc54a\uc740 \ub9c9, \uc6d0\ud615\uc9c8\ub9c9 \uc218\ud3ec, \uc5fc\uc0c9\uc9c8 \uc751\ucd95, DNA \ub2e8\ud3b8\ud654 \ub4f1\uc73c\ub85c \uc778\ud574 \uc138\ud3ec\uac00 \uc218\ucd95\ub429\ub2c8\ub2e4.<\/td>\n<td>\uc0dd\ub9ac\uc801 \uc0c1\ud0dc\uc758 \uc720\uc804\uc790 \uc870\uc808<\/td>\n<td>\uc870\uc808 \uce74\uc2a4\ud30c\uc81c \uacc4\uc5f4, Bcl-2 \uacc4\uc5f4, p53 \ub4f1<\/td>\n<td><a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib37\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib37\"><span class=\"anchor-text\">[37]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib38\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib38\"><span class=\"anchor-text\">[38]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib39\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib39\"><span class=\"anchor-text\">[39]<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\uad34\uc0ac\uc99d<\/th>\n<td>\uad34\uc0ac<\/td>\n<td>\uc138\ud3ec \ubd80\uc885, \uc6d0\ud615\uc9c8\ub9c9 \ud30c\uc5f4, \uc18c\uae30\uad00 \ubd80\uc885, \uc5fc\uc0c9\uc9c8 \uc751\ucd95 \ub4f1<\/td>\n<td>\uc2ec\uac01\ud55c \ubd80\uc0c1<\/td>\n<td>Nec-1, NSA \ub4f1<\/td>\n<td><a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib33\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib33\"><span class=\"anchor-text\">[33]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib40\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib40\"><span class=\"anchor-text\">[40]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib41\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib41\"><span class=\"anchor-text\">[41]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib42\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib42\"><span class=\"anchor-text\">[42]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib43\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib43\"><span class=\"anchor-text\">[43]<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">Ferroptosis<\/th>\n<td>NRF2, GPX4, ACSL4 \ub4f1<\/td>\n<td>\uc8fc\ub85c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\uc5d0\uc11c \ubc1c\uc0dd\ud558\uba70 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ud06c\ub9ac\uc2a4\ud0c0\uac00 \uac10\uc18c\ud558\uace0 \ub9c9\uc774 \uc751\ucd95\ub418\uace0 \uc678\ub9c9\uc774 \ud30c\uc5f4\ub429\ub2c8\ub2e4.<\/td>\n<td>Fe2 + \uacfc\ubd80\ud558 \ubc0f ROS<\/td>\n<td>GSH, \ub370\ud398\ub85d\uc0ac\ubbfc, \ub9ac\ud504\ub85d\uc2a4\ud0c0\ud2f4-1, \ud398\ub85c\uc2a4\ud0c0\ud2f4-1 \ub4f1<\/td>\n<td><a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib44\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib44\"><span class=\"anchor-text\">[44]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib45\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib45\"><span class=\"anchor-text\">[45]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib46\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib46\"><span class=\"anchor-text\">[46]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib47\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib47\"><span class=\"anchor-text\">[47]<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n<section id=\"sec0020\">\n<h3 id=\"sect0040\" class=\"u-h4 u-margin-m-top u-margin-xs-bottom\">2.2. \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc758 \ubd84\uc790 \uba54\ucee4\ub2c8\uc998<\/h3>\n<p id=\"p0040\">\ud615\uc131\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc778\ud50c\ub77c\ub9c8\uc19c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/inflammasome\">\uc5fc\uc99d<\/a>\u00a0\ubd80\uc0c1 \ud6c4 \ubc1c\uc5f4\uc99d\uc758 \ud575\uc2ec \ubb3c\uc9c8\uc785\ub2c8\ub2e4. \ubd80\uc0c1\uc744 \uc785\uc73c\uba74 \uc2e0\uccb4\ub294 \ubcd1\uc6d0\uccb4 \uad00\ub828 \ubd84\uc790 \ud328\ud134(PAMP) \ubc0f \uc190\uc0c1 \uad00\ub828 \ubd84\uc790 \ud328\ud134(DAMP)\uacfc \uad00\ub828\ub41c \ud328\ud134 \uc2e0\ud638\ub97c \ud65c\uc131\ud654\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib48\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib48\"><span class=\"anchor-text\">[48]<\/span><\/a>. \uc2e0\ud638 \uc790\uadf9\uc774 \ubc1c\uc0dd\ud558\uba74 \uc138\ud3ec \ub0b4\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud504\ub85c\ubaa8\ud130 \ub2e8\ubc31\uc9c8\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/promoter-protein\">\ud504\ub85c\ubaa8\ud130 \ub2e8\ubc31\uc9c8<\/a>\u00a0\ub274\ud074\ub808\uc624\ud2f0\ub4dc \uacb0\ud569 \uc62c\ub9ac\uace0\uba38\ud654 \ub3c4\uba54\uc778 \uc720\uc0ac \uc218\uc6a9\uccb4\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c pyrin \ub3c4\uba54\uc778\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/pyrin-domain\">\ud53c\ub9b0 \ub3c4\uba54\uc778<\/a>\u00a03(NLRP3)\uc744 \ud568\uc720\ud558\ub294 \uac83\uc740 \uc62c\ub9ac\uace0\uba38\ud654\ub97c \ud1b5\ud574 \uc5fc\uc99d\ubcf5\ud569\uccb4 \uc5b4\ub311\ud130 \ubd84\uc790 ASC\ub97c \uc0ac\uc6a9\ud558\uc5ec \ub300\ub7c9\uc758 \ud504\ub85c\uce74\uc2a4\ud30c\uc81c-1\uc744 \ubaa8\uc9d1\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib49\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib49\"><span class=\"anchor-text\">[49]<\/span><\/a>, \uc5fc\uc99d\ubcf5\ud569\uccb4 \uc751\uc9d1 \ub2e8\ubc31\uc9c8\uc758 \ud615\uc131. \ud504\ub85c\uce74\uc2a4\ud30c\uc81c-1\uc740 \uce74\uc2a4\ud30c\uc81c-1\uc758 \uc804\uad6c\uccb4\uc774\uba70, \uc77c\ubc18\uc801\uc73c\ub85c \ud504\ub85c\uce74\uc2a4\ud30c\uc81c-1\uc740 \uccb4\ub0b4\uc5d0 \ub2e4\uc74c\uacfc \uac19\uc740 \ud615\ud0dc\ub85c \uc874\uc7ac\ud569\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc790\uc774\ubaa8\uac90\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/enzyme-precursor\">\ubc1c\ud6a8\uade0<\/a>. \uc790\uadf9 \uc2e0\ud638\uac00 \ud504\ub85c\uce74\uc2a4\ud30c\uc81c-1\uc5d0 \uc804\ub2ec\ub418\uba74 \uc790\uac00\uac00\uc218\ubd84\ud574\uc5d0 \uc758\ud574 P20 \ubc0f P10 \ud558\uc704 \ub2e8\uc704\uac00 \uc0dd\uc131\ub429\ub2c8\ub2e4. \uc774 \ud558\uc704 \ub2e8\uc704\ub294 \uba3c\uc800\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc774\uc885\uc774\ud569\uccb4\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/heterodimer\">\uc774\uc885\uc774\ub7c9\uccb4<\/a>\u00a0\uae30\ub2a5\ud558\uc9c0 \ubabb\ud558\ub294 \uac83\uc774 \ubaa8\uc5ec\uc11c \ud558\ub098\uc758 \ud615\ud0dc\ub97c \uc774\ub8ec\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc0ac\ub7c9\uccb4\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/tetramer\">\uc0ac\ub7c9\uccb4<\/a>\u00a0\uce74\uc2a4\ud30c\uc81c-1 \ud65c\uc131\uc744 \ucd09\uc9c4\ud558\uc5ec \uce74\uc2a4\ud30c\uc81c-1 \ud65c\uc131\ud654\ub97c \uc720\ub3c4\ud558\ub294 \ubb3c\uc9c8\uc785\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib50\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib50\"><span class=\"anchor-text\">[50]<\/span><\/a>. \uce74\uc2a4\ud30c\uc81c-1\uc774 \ud65c\uc131\ud654\ub418\uba74 \ud65c\uc131 \uce74\uc2a4\ud30c\uc81c-1\uc740 \uc138\ud3ec\ub9c9 \uad6c\uba4d\uc758 \ud615\uc131\uacfc \uc138\ud3ec\ub9c9\uc758 \uc2e0\uc18d\ud55c \uc6a9\ud574\ub97c \ub2f4\ub2f9\ud558\uc5ec \uc5fc\uc99d \ubc18\uc751\uc744 \ud615\uc131\ud569\ub2c8\ub2e4. \ud55c\ud3b8, \uce74\uc2a4\ud30c\uc81c-1\uc740 IL-1\u03b2 \ubc0f IL-18\uc758 \uc804\uad6c\uccb4\uc778 pro-IL-1\u03b2 \ubc0f pro-IL-18\uc744 \uc720\ub3c4\ud558\uc5ec \uc131\uc219 \uacfc\uc815\uc744 \uac00\uc18d\ud654\ud560 \uc218\ub3c4 \uc788\uc2b5\ub2c8\ub2e4. \uc131\uc219\ud55c IL-1\u03b2\uc640 IL-18\uc740 \uc138\ud3ec\uc678\ub85c \ubc29\ucd9c\ub418\uc5b4 \ub354 \ub9ce\uc740 \uc5fc\uc99d\ubcf5\ud569\uccb4\ub97c \ubaa8\uc9d1\ud569\ub2c8\ub2e4. \uc778\ud50c\ub77c\ub9c8\uc19c\uc774 \uc751\uc9d1\ub41c \ud6c4\uc5d0\ub294 \uc5fc\uc99d \ubc18\uc751\uc774 \ub354\uc6b1 \uc545\ud654\ub418\uace0 \uc870\uc9c1 \uc190\uc0c1\uc774 \ub354\uc6b1 \uc545\ud654\ub429\ub2c8\ub2e4. IL-1\u03b2\uac00 \uc138\ud3ec\uc5d0\uc11c \ubc29\ucd9c\ub41c \ud6c4 \uc5fc\uc99d \uc778\uc790\ub294 \ub9bc\ud504\uc758 \ud750\ub984\uc744 \ub530\ub77c \uc778\uc811\ud55c \uc870\uc9c1\uc73c\ub85c \ud37c\uc838 \uc5fc\uc99d \ubc18\uc751\uc744 \ub354\uc6b1 \uc545\ud654\uc2dc\ud0b5\ub2c8\ub2e4. IL-18\uc774 \ub2e4\ub7c9 \ubd84\ube44\ub418\uba74 Th1, Th2 \uba74\uc5ed\ubc18\uc751\uc774 \uc77c\uc5b4\ub098\uba70, \uba74\uc5ed\ubc18\uc751\uc744 \uc790\uadf9\ud558\uc5ec \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib51\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib51\"><span class=\"anchor-text\">[51]<\/span><\/a>.<\/p>\n<section id=\"sec0025\">\n<h4 id=\"sect0045\" class=\"u-margin-m-top u-margin-xs-bottom\">2.2.1. \uc815\uc2dd \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uacbd\ub85c<\/h4>\n<p id=\"p0045\">\uce74\uc2a4\ud30c\uc81c-1\uc740 \uc778\ud50c\ub77c\ub9c8\uc19c\uc774 \uce74\uc2a4\ud30c\uc81c-1\uc758 \ud65c\uc131\ud654\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud558\ub294 \ud45c\uc900 \ubc1c\uc5f4 \uacbd\ub85c\uc758 \ud575\uc2ec \ub2e8\ubc31\uc9c8\uc785\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib52\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib52\"><span class=\"anchor-text\">[52]<\/span><\/a>. \uc778\ud50c\ub77c\ub9c8\uc19c\uc740 \uc120\ucc9c\uc131 \uba74\uc5ed \uccb4\uacc4\uc758 \uc911\uc694\ud55c \ubd80\ubd84\uc774\uba70 \uc13c\uc11c \ub2e8\ubc31\uc9c8, ASC \ubc0f pro-Caspase-1\ub85c \uad6c\uc131\ub41c \ub2e4\uc911 \ub2e8\ubc31\uc9c8 \ubcf5\ud569\uccb4\uc785\ub2c8\ub2e4. \uc790\uadf9\ubc1b\uc740 \uc138\ud3ec\uc9c8\uc5d0 \uc874\uc7ac\ud55c\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uba74\uc5ed \uc138\ud3ec\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/immunocompetent-cell\">\uba74\uc5ed\uc138\ud3ec<\/a>\u00a0\uc138\ud3ec\uc678 \uc790\uadf9 \uc2e0\ud638\ub97c \uac10\uc9c0\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib53\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib53\"><span class=\"anchor-text\">[53]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib54\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib54\"><span class=\"anchor-text\">[54]<\/span><\/a>. \uc778\ud50c\ub77c\ub9c8\uc880\uc740 \ub274\ud074\ub808\uc624\ud0c0\uc774\ub4dc \uacb0\ud569 \uc62c\ub9ac\uace0\uba38\ud654 \ub3c4\uba54\uc778 \uc720\uc0ac \uc218\uc6a9\uccb4(NLR)\ub97c \ud3ec\ud568\ud558\ub294 \uc778\ud50c\ub77c\ub9c8\uc880\uc73c\ub85c \ub098\ub204\uc5b4\uc9d1\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud751\uc0c9\uc885\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/nodular-melanoma\">\ud751\uc0c9\uc885<\/a>\u00a02(AIM2) \uc778\ud50c\ub77c\ub9c8\uc19c \ubc0f NLRC4 \uc778\ud50c\ub77c\ub9c8\uc19c\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib55\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib55\"><span class=\"anchor-text\">[55]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib56\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib56\"><span class=\"anchor-text\">[56]<\/span><\/a>. Purinergic 2 \u00d7 7 (P2X7) \uc218\uc6a9\uccb4\ub294 ATP-gated transmembrane \uc774\uc628 \ucc44\ub110 \uc218\uc6a9\uccb4\ub85c \ub2e4\uc74c\uacfc \uac19\uc774 \ud45c\ud604\ub429\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc18c\uad50\uc138\ud3ec\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/microglia\">\uc18c\uad50\uc138\ud3ec<\/a>\u00a0\uc5fc\uc99d\ubcf5\ud569\uccb4 \ud65c\uc131\ud654\uc758 \ud575\uc2ec \uc694\uc18c\uc785\ub2c8\ub2e4. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \uc138\ud3ec\uc678 ATP\ub294 \ub2e4\uc74c\uc744 \ud65c\uc131\ud654\ud558\uc5ec K+ \uc720\ucd9c\uc744 \uc870\uc808\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c P2X7 \uc218\uc6a9\uccb4\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/purinergic-p2x7-receptor\">P2X7 \uc218\uc6a9\uccb4<\/a>, NLR \uacc4\uc5f4\uc778 \ud53c\ub9b0 \ub3c4\uba54\uc778 \ud568\uc720 3(NLRP3)\uc758 \ud65c\uc131\ud654\ub97c \uc720\ub3c4\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib57\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib57\"><span class=\"anchor-text\">[57]<\/span><\/a>. NLRP3 \uc778\ud50c\ub77c\ub9c8\uc19c\uc740 \ud604\uc7ac \uac00\uc7a5 \ub9ce\uc774 \uc5f0\uad6c\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4. NLRP3 \uc778\ud50c\ub77c\ub9c8\uc19c\uc758 \ud65c\uc131\ud654\uc5d0\ub294 2\ub2e8\uacc4 \ubc18\uc751\uc774 \ud544\uc694\ud569\ub2c8\ub2e4. \ubc18\uc751\uc758 \uac1c\uc2dc, \ubbf8\uc0dd\ubb3c \ub610\ub294 \ub0b4\uc778\uc131 \uc778\uc790 \ud575\uc778\uc790-\u03baB(NF-\u03baB)\uc758 \ud575 \ub0b4\ub85c\uc758 \ubc18\uc751 \uac1c\uc2dc, NLRP3 \ubc0f pro-IL-1\u03b2 \ubc1c\ud604\uc758 \uc0c1\ud5a5 \uc870\uc808\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib58\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib58\"><span class=\"anchor-text\">[58]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib59\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib59\"><span class=\"anchor-text\">[59]<\/span><\/a>. \uba74\uc5ed \uc138\ud3ec\uac00 DAMP\uc5d0 \uc758\ud574 \uc790\uadf9\ub418\uba74 \uc13c\uc11c \ub2e8\ubc31\uc9c8\uc740 ASC\ub97c \ud1b5\ud574 pro-Caspase-1\uc744 \ubaa8\uc9d1\ud558\uace0 \uc790\uac00 \uac00\uc218\ubd84\ud574\uc5d0 \uc758\ud574 \ud65c\uc131\ud654\ub429\ub2c8\ub2e4. \uc131\uc219\ud55c Caspase-1\uc740 \ud558\ub958\uc758 \ube44\ud65c\uc131 pro-IL-1\u03b2 \ubc0f pro-IL-18\uc744 \ud65c\uc131 IL-1\u03b2 \ubc0f IL-18\ub85c \ucc98\ub9ac\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib60\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib60\"><span class=\"anchor-text\">[60]<\/span><\/a>. \ud55c\ud3b8, \uce74\uc2a4\ud30c\uc81c-1\uc740 \ub2e4\uc6b4\uc2a4\ud2b8\ub9bc GSDMD \ub2e8\ubc31\uc9c8\uc744 \uae30\uacf5 \ud615\uc131 \ud65c\uc131\uc744 \uac16\ub294 GSDMD-N \ub2e8\ud3b8 \ubc0f GSDMD-C \ub2e8\ud3b8\uc73c\ub85c \uc808\ub2e8\ud569\ub2c8\ub2e4. GSDMD-N \ub2e8\ud3b8\uc740 \ud2b9\uc774\uc801\uc73c\ub85c \ub2e4\uc74c\uc744 \uc778\uc2dd\ud558\uace0 \uacb0\ud569\ud569\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub9c9 \uc9c0\uc9c8\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/membrane-lipid\">\ub9c9\uc9c0\uc9c8<\/a>\u00a0\uc138\ud3ec\ub9c9 \uc548\ucabd\uc5d0 \uc874\uc7ac\ud558\uc5ec \uc138\ud3ec\ub0b4 \ubc0f \uc138\ud3ec\uc678 \uc0bc\ud22c\uc555\uc758 \ubcc0\ud654\ub97c \uc77c\uc73c\ud0a4\uace0 \uc774\ub85c \uc778\ud574 \uc138\ud3ec\uac00 \ubd80\ud480\uc5b4 \uc624\ub974\uace0 \ud30c\uc5f4\ub418\uba70 \uc5fc\uc99d\uc778\uc790 IL-1\u03b2 \ubc0f IL-18\uc774 \ubc29\ucd9c\ub418\uc5b4 \uc5fc\uc99d\ubc18\uc751 \ubc0f \uc138\ud3ec \ubc1c\uc5f4\uc99d\uc744 \uc720\ubc1c\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib61\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib61\"><span class=\"anchor-text\">[61]<\/span><\/a>.<\/p>\n<\/section>\n<section id=\"sec0030\">\n<h4 id=\"sect0050\" class=\"u-margin-m-top u-margin-xs-bottom\">2.2.2. \ube44\uc815\uaddc \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uacbd\ub85c<\/h4>\n<p id=\"p0050\">Caspase \uacc4\uc5f4\uc740 \uc8fc\ub85c \uae30\ub2a5\uc5d0 \ub530\ub77c \uc138\ud3ec\uc0ac\uba78 \uad00\ub828 \ubc0f \uc5fc\uc99d \uad00\ub828 \ub450 \uac00\uc9c0 \ubc94\uc8fc\ub85c \ub098\ub269\ub2c8\ub2e4. \uce74\uc2a4\ud30c\uc81c-3\/2\/10\uc740 \uc8fc\ub85c \uc138\ud3ec\uc0ac\uba78\uc744 \uc911\uc7ac\ud558\ub294 \ubc18\uba74, \uce74\uc2a4\ud30c\uc81c-1\/4\/5\/11\uc740 \uc5fc\uc99d\uacfc \uc120\ucc9c\uc801 \uba74\uc5ed \ubc18\uc751\uc758 \ud575\uc2ec \uc911\uc7ac\uc790\uc785\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib62\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib62\"><span class=\"anchor-text\">[62]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib63\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib63\"><span class=\"anchor-text\">[63]<\/span><\/a>. \ube44\ud45c\uc900 pyroptotic \uacbd\ub85c\ub294 Caspase-4\/5\/11 \ud65c\uc131\ud654\uc5d0 \uc758\uc874\ud558\ub294 \ubc18\uba74, inflammasome\uc740 IL-1\u03b2 \ubc0f IL-18\uc758 \uc131\uc219\uc5d0 \ud544\uc218\uc801\uc774\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib64\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib64\"><span class=\"anchor-text\">[64]<\/span><\/a>. \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc758 \ube44\uace0\uc804\uc801 \uacbd\ub85c\ub294 \ub2e4\uc74c\uc5d0 \uc758\ud574 \uc720\ubc1c\ub429\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc9c0\uc9c8\ub2e4\ub2f9\ub958\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/lipopolysaccharide\">\uc9c0\uc9c8\ub2e4\ub2f9\ub958<\/a>\u00a0(LPS)\ub294 \uadf8\ub78c \uc74c\uc131\uade0\uc758 \uc138\ud3ec\ubcbd \uc131\ubd84\uc785\ub2c8\ub2e4. LPS\ub294 \uc778\uac04 Caspase-4\/5 \ubc0f \ub9c8\uc6b0\uc2a4 Caspase-11\uc5d0 \uc9c1\uc811 \uacb0\ud569\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uce74\uc2a4\ud30c\uc81c\ub294 LPS\uc758 \uc13c\uc11c \ub2e8\ubc31\uc9c8\uacfc \uc774\ud399\ud130 \ubd84\uc790 \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \ud65c\uc131\ud654\ub41c Caspase-4\/5\/11\uc740 GSDMD\ub97c \uc9c1\uc811 \uc808\ub2e8\ud558\uace0 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc720\ub3c4\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib65\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib65\"><span class=\"anchor-text\">[65]<\/span><\/a>. \ub610\ud55c \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 Caspase-11\uc740 \ub2e4\uc6b4\uc2a4\ud2b8\ub9bc\uc744 \ud65c\uc131\ud654\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uac04\uaca9 \uc811\ud569\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/gap-junction\">\uac04\uaca9 \uc811\ud569<\/a>\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ucc44\ub110 \ub2e8\ubc31\uc9c8\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/channel-protein\">\ucc44\ub110 \ub2e8\ubc31\uc9c8<\/a>\u00a0K+ \uc720\ucd9c\uc744 \ucd09\uc9c4\ud558\ub294 Pannexin-1\uacfc K+ \uc720\ucd9c\uc740 NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4\ub97c \ud65c\uc131\ud654\ud560 \uc218 \uc788\uc73c\uba70, \uc774\ub294 \ucc28\ub840\ub85c Caspase-1\uc744 \ud65c\uc131\ud654\ud558\uace0 IL-1\u03b2 \ubc0f IL-18\uc758 \uc131\uc219\uc744 \ucd09\uc9c4\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib66\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib66\"><span class=\"anchor-text\">[66]<\/span><\/a>.<\/p>\n<\/section>\n<section id=\"sec0035\">\n<h4 id=\"sect0055\" class=\"u-margin-m-top u-margin-xs-bottom\">2.2.3. GSDMD\uc640 \ubc1c\uc5f4\uc99d\uc758 \uad00\uacc4<\/h4>\n<p id=\"p0055\">GSDMD(Gsdermin D)\ub294 484\uac1c\uc758 \uc544\ubbf8\ub178\uc0b0 \uc794\uae30 \ub2e8\ud3b8\uc73c\ub85c \uad6c\uc131\ub41c \ub2e8\ubc31\uc9c8\uc774\uba70 Gasdermin \ub2e8\ubc31\uc9c8 \uacc4\uc5f4\uc758 \uad6c\uc131\uc6d0\uc785\ub2c8\ub2e4. \uc774 \uacc4\uc5f4\uc5d0\ub294 \uc8fc\ub85c DFNA5, DFNB59, GSDMA, GSDMB, GSDMCD \ub4f1 5\uac1c\uc758 \uad6c\uc131\uc6d0\uc774 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub4e4 5\uac1c \ub2e8\ubc31\uc9c8\uc758 \uc544\ubbf8\ub178\uc0b0 \uad6c\uc870\ub294 \ub9e4\uc6b0 \uc720\uc0ac\ud558\uba70, \uc774\ub4e4 \ub2e8\ubc31\uc9c8\uc740 N-\ub9d0\ub2e8\uacfc C-\ub9d0\ub2e8\uc774\ub77c\ub294 \ub450 \uac1c\uc758 \uacf5\uac04 \ub3c4\uba54\uc778\uc744 \ud3ec\ud568\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib67\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib67\"><span class=\"anchor-text\">[67]<\/span><\/a>. GSDMD \ub2e8\ubc31\uc9c8\uc740 \uc7a5\uc1c4 \uc544\ubbf8\ub178\uc785\ub2c8\ub2e4\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc0b0\uc131 \ub2e8\ubc31\uc9c8\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/acid-protein\">\uc0b0\uc131 \ub2e8\ubc31\uc9c8<\/a>, N \ub9d0\ub2e8 \ub3c4\uba54\uc778\uacfc C \ub9d0\ub2e8 \ub3c4\uba54\uc778 \uc0ac\uc774\uc758 \uad6c\uc870\ub294 \uc0c1\ub300\uc801\uc73c\ub85c \ub290\uc2a8\ud569\ub2c8\ub2e4. GSDMD\ub294 \uc77c\ubc18\uc801\uc73c\ub85c \ub2e4\uc74c\uc5d0\uc11c \uc808\ub2e8\ub429\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc544\ubbf8\ub178\uc0b0 \uc11c\uc5f4\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/peptide-sequence\">\uc544\ubbf8\ub178\uc0b0 \uc11c\uc5f4<\/a>\u00a0275, N-\ub9d0\ub2e8 \ubc0f C-\ub9d0\ub2e8 \ub3c4\uba54\uc778 \ub178\ucd9c. ~ \uc548\uc5d0\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud3ec\uc720\ub958 \uc138\ud3ec\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/mammalian-cell\">\ud3ec\uc720\ub958 \uc138\ud3ec<\/a>, GSDMD\uc758 \ub2e8\uc21c\ud55c N \ub9d0\ub2e8 \uad6c\uc870\ub294 \uc138\ud3ec \ubc1c\uc5f4\uc744 \uc870\uc808\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c GSDMD\ub294 N-\ub9d0\ub2e8 \ub3c4\uba54\uc778\uc744 \ubc1c\ud604\ud558\ub294 \uacbd\uc6b0\uac00 \ub9ce\uc9c0\ub9cc \ubaa8\ub4e0 GSDMD \ub2e8\ubc31\uc9c8\uc744 \ubc1c\ud604\ud560 \uc218\ub294 \uc5c6\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib68\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib68\"><span class=\"anchor-text\">[68]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib69\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib69\"><span class=\"anchor-text\">[69]<\/span><\/a>. \uadf8\ub7ec\ub098 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 GSDMD\uc758 N \ub9d0\ub2e8 \ub3c4\uba54\uc778\uc744 \ub300\uc7a5\uade0\uc5d0 \ub3c4\uc785\ud558\uc5ec \ubc30\uc591\ud558\uba74 \uac15\ud55c \ub3c5\uc131 \ud6a8\uacfc\uac00 \ubc1c\uc0dd\ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \ub300\uc870\uc801\uc73c\ub85c, \uc190\uc0c1\ub418\uc9c0 \uc54a\uc740 GSDMD \ubc0f GSDMD\uc758 C-\ub9d0\ub2e8 \ub3c4\uba54\uc778\uc740 \uc0c1\ub300\uc801\uc73c\ub85c \ub0ae\uc740 \ub3c5\uc131\uc744 \ub098\ud0c0\ub0c8\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib70\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib70\"><span class=\"anchor-text\">[70]<\/span><\/a>. \uc138\ud3ec\ub0b4 GSDMD\uc758 N \ub9d0\ub2e8 \uad6c\uc870\ub294 \uc190\uc0c1 \uc694\uc778\uc758 \uce68\uc785\uacfc \ud568\uaed8 \uc810\ucc28\uc801\uc73c\ub85c \uc138\ud3ec\ub9c9\uc73c\ub85c \uc774\ub3d9\ud558\uace0, \uc138\ud3ec\ub9c9\uc5d0\uc11c\ub294 \ud3ec\uc2a4\ud3ec\uc0ac\ub974\ucf54\uc2dc\ub098\uc81c\uc640 \ud2b9\uc774\uc801\uc73c\ub85c \uacb0\ud569\ud569\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud3ec\uc2a4\ud30c\ud2f0\ub51c\uc138\ub9b0\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/phosphatidylserine\">\ud3ec\uc2a4\ud30c\ud2f0\ub51c\uc138\ub9b0<\/a>\u00a0\uc138\ud3ec\ub9c9\uc5d0 \uc0dd\ubb3c\ud559\uc801 \ud6a8\uacfc\ub97c \uc0dd\uc131\ud558\uae30 \uc704\ud574\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib71\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib71\"><span class=\"anchor-text\">[71]<\/span><\/a>. \uc6d0\uc790\ub825\uacfc \uac19\uc740 \uc7a5\ube44\ub97c \uc0ac\uc6a9\ud558\uc5ec\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc804\uc790 \ud604\ubbf8\uacbd\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/electron-microscopy\">\uc804\uc790\ud604\ubbf8\uacbd<\/a>\u00a0L. Sborigi\ub294 \uc800\uc628\uc804\uc790\ud604\ubbf8\uacbd\uc744 \ud1b5\ud574 GSDMD\uc758 N \ub9d0\ub2e8 \uad6c\uc870\uac00 \uc0dd\ubb3c\ub9c9\uacfc \uacb0\ud569\ub418\uc5b4 \uc0dd\ubb3c\ub9c9\uc5d0 \uc18d\uc774 \ube48 \uace0\ub9ac\ud615 \uc911\ud569\uccb4\ub97c \ud615\uc131\ud560 \uc218 \uc788\uc74c\uc744 \uad00\ucc30\ud588\uc2b5\ub2c8\ub2e4. \uc774 \uc911\ud569\uccb4\ub294 \uc0dd\ubb3c\ub9c9 \uacf5\uadf9\uc758 \ud615\uc131\uc744 \uc720\ub3c4\ud558\uba70, \uc774\ub85c \uc778\ud574 GSDMD\ub294 \ub0b4\uc778\uc131 \uc190\uc0c1\uc774 \ubc1c\uc0dd\ud560 \ub54c \uc138\ud3ec\uc5d0\uc11c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc720\ub3c4\ud569\ub2c8\ub2e4. \uc678\ubd80\uc77c \ub54c\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ubcd1\uc6d0\uccb4\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/pathogen\">\ubcd1\uc6d0\uccb4<\/a>\u00a0\uce68\uc785\ud558\uc5ec \ubcd1\uc6d0\uade0\uc758 \uc138\ud3ec\ud45c\uba74\uc5d0 \ud761\ucc29\ud558\uace0, \uc138\ud3ec\ub97c \uc6a9\ud574\uc2dc\ucf1c \uc678\ubd80 \uc720\ud574\ubb3c\uc9c8\ub85c\ubd80\ud130 \uc2e0\uccb4\ub97c \ubcf4\ud638\ud558\ub294 \uc5ed\ud560\uc744 \ud55c\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib72\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib72\"><span class=\"anchor-text\">[72]<\/span><\/a>. GSDMD\ub294 \ud558\ub958\uc758 \uce74\uc2a4\ud30c\uc81c-1\/4\/5\/11 \ub2e8\ubc31\uc9c8\uc5d0 \ud2b9\uc774\uc801\uc73c\ub85c \uacb0\ud569\ud558\ub294 \ubb3c\uc9c8\uc785\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc2e0\ud638 \ubcc0\ud658\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/signal-transduction\">\uc2e0\ud638 \ubcc0\ud658<\/a>\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib73\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib73\"><span class=\"anchor-text\">[73]<\/span><\/a>. \uce74\uc2a4\ud30c\uc81c-1\uc740 \ub2e4\uc591\ud55c \ub2e8\ubc31\uc9c8\uacfc\uc758 \ubcf5\ud569\uccb4\uc5d0 \uc758\ud574 \uc0dd\uc131\ub41c \uc5fc\uc99d\ubcf5\ud569\uccb4 \ubc18\uc751\uc744 \ud1b5\ud574 \uc138\ud3ec\ub9c9 \ubc16\uc73c\ub85c \ud558\ub958 IL-1\u03b2 \ubc0f IL-18\uc758 \ubc29\ucd9c\uc744 \ucd09\uc9c4\ud569\ub2c8\ub2e4. \ud65c\uc131\ud654\ub41c \uce74\uc2a4\ud30c\uc81c-1\uc740 GSDMD \ub2e8\ubc31\uc9c8\uc744 \uc808\ub2e8\ud558\uc5ec GSDMD\ub97c \ud65c\uc131 \ud3a9\ud0c0\uc774\ub4dc\ub85c \uc804\ud658\ud569\ub2c8\ub2e4. GSDMD\uc758 \ubd84\ud574\uc0b0\ubb3c\uc774 \uc138\ud3ec\ub9c9\uc5d0 \ud2b9\uc774\uc801\uc73c\ub85c \uacb0\ud569\ud558\uc5ec \uc138\ud3ec\uc678 \ubb3c\ubd84\uc790 \ub4f1\uc758 \uc131\ubd84\uc774 \uae30\uacf5\uc744 \ud1b5\ud574 \uc138\ud3ec\ub9c9 \uc548\uc73c\ub85c \ub4e4\uc5b4\uac00 \uc138\ud3ec\uac00 \ubd80\ud480\uc5b4\uc624\ub974\uac8c \ub418\uc5b4 \uacb0\uad6d \ud30c\uc5f4\ub418\uac8c \ub41c\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib74\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib74\"><span class=\"anchor-text\">[74]<\/span><\/a>.<\/p>\n<\/section>\n<\/section>\n<section id=\"sec0040\">\n<h3 id=\"sect0060\" class=\"u-h4 u-margin-m-top u-margin-xs-bottom\">2.3. Noncoding RNA\ub294 IS\uc5d0\uc11c pyroptotic \uc720\uc804\uc790\uc758 \ubc1c\ud604\uc5d0 \ucc38\uc5ec\ud569\ub2c8\ub2e4.<\/h3>\n<p id=\"p0060\">\ucd5c\uadfc\uc5d0\ub294 \ubc1c\uc5f4\uc99d \ubc1c\uc0dd\uacfc \uad00\ub828\ub41c \uc720\uc804\uc790 \uc218\uc900\uc758 \uc870\uc808 \uba54\ucee4\ub2c8\uc998\ub3c4 \uc644\uc804\ud788 \uac1c\ubc1c\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ud604\ub300 \ubd84\uc790 \uc0dd\ubb3c\ud559 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \uac8c\ub188\uc758 98%\ub294 \ub2e8\ubc31\uc9c8 \ucf54\ub529\uc5d0 \uad00\uc5ec\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \uc7a5\uc1c4 \ucf54\ub529 RNA(lncRNA)\ub294 \ub2e8\ubc31\uc9c8 \ucf54\ub529 \uae30\ub2a5\uc774 \uc5c6\ub294 RNA\ub85c, \uae38\uc774\uac00 200\uac1c \uc774\uc0c1\uc758 \ub274\ud074\ub808\uc624\ud2f0\ub4dc\uc774\uae30 \ub54c\ubb38\uc5d0 \uc774\ub7ec\ud55c \uc774\ub984\uc774 \ubd99\uc5c8\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib75\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib75\"><span class=\"anchor-text\">[75]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib76\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib76\"><span class=\"anchor-text\">[76]<\/span><\/a>. \uadf8\ub7ec\ub098 \ube44\ub85d ~ \uc77c\uc9c0\ub77c\ub3c4\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c lncRNA\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/long-untranslated-rna\">lncRNA<\/a>\u00a0\ub2e8\ubc31\uc9c8\uc744 \uc554\ud638\ud654\ud558\ub294 \uae30\ub2a5\uc740 \uc5c6\uc9c0\ub9cc \uccb4\ub0b4\uc5d0\uc11c \uac00\uc7a5 \ub9ce\uc774 \ubc1c\ud604\ub418\ub294 \uc720\uc804\uc790\uc774\uc790 \uc804\uc0ac\uc5d0\uc11c \uac00\uc7a5 \uc798 \ubcf4\uc874\ub418\ub294 \uc720\uc804\uc790\uc774\ub2e4. \uc2e0\uccb4\uc758 \uc911\uc694\ud55c \ubcd1\ub9ac\ud559\uc801, \uc0dd\ub9ac\ud559\uc801 \uacfc\uc815, \ud2b9\ud788 \uc7ac\uad00\ub958 \uc190\uc0c1 \uad00\ub828 \uc9c8\ud658\uc5d0 \ucc38\uc5ec\ud558\uba70 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib77\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib77\"><span class=\"anchor-text\">[77]<\/span><\/a>. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \uc18c\uad50\uc138\ud3ec\uc5d0\uc11c lncRNA-H19\uc758 \ubc1c\ud604 \uc218\uc900\uc740 \uc7ac\uad00\ub958 \uae30\uac04\uacfc \uc591\uc758 \uc0c1\uad00\uad00\uacc4\uac00 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib78\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib78\"><span class=\"anchor-text\">[78]<\/span><\/a>. LncRNA-H19\uc758 \uacfc\ubc1c\ud604\uc740 \ud558\ub958 \uc2e0\ud638 \ubd84\uc790 NLRP3\/6\uc758 \ubc1c\ud604\uc744 \ucd09\uc9c4\ud558\uace0 GSDMD\ub97c \uac1c\uc2dc\ud560 \ub54c \uc5fc\uc99d \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib79\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib79\"><span class=\"anchor-text\">[79]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib80\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib80\"><span class=\"anchor-text\">[80]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib81\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib81\"><span class=\"anchor-text\">[81]<\/span><\/a>. lncRNA-H19\ub294 \uce74\uc2a4\ud30c\uc81c \ub2e8\ubc31\uc9c8 \uacc4\uc5f4 \uad6c\uc131\uc6d0\uc744 \ud65c\uc131\ud654\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib82\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib82\"><span class=\"anchor-text\">[82]<\/span><\/a>, \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uae30\ub2a5 \uc7a5\uc560\ub85c \uc774\uc5b4\uc9c0\uace0 \uc5fc\uc99d\ubcf5\ud569\uccb4 \ud65c\uc131\ud654\uc5d0 \ucc38\uc5ec\ud558\uba70 \uc2e0\uacbd \uc190\uc0c1\uc744 \uc720\ubc1c\ud569\ub2c8\ub2e4\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib83\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib83\"><span class=\"anchor-text\">[83]<\/span><\/a>. lncRNA-H19\ub294 \ubd84\uc790 \uad6c\uc870\uc758 \uc870\uc808 \uc678\uc5d0\ub3c4 mRNA \uc804\uc0ac \uacfc\uc815\uc744 \uc870\uc808\ud558\uae30 \uc704\ud574 \ub354 \ub9ce\uc740 \uc804\uc0ac \uc778\uc790\ub97c \ubaa8\uc9d1\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib84\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib84\"><span class=\"anchor-text\">[84]<\/span><\/a>. \ub610\ud55c, lncRNA-H19\ub294 \ub2e4\uc74c\uc744 \ucd09\uc9c4\ud560 \uc218\ub3c4 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc6d0\uc790\ub825 \uc6b4\uc1a1\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/nucleocytoplasmic-transport\">\ud575 \uc218\uc1a1<\/a>\u00a0\uc804\uc0ac \uc778\uc790\uc758 \uacfc\uc815\uc744 \ud1b5\ud574 \ub354 \ub9ce\uc740 \ud45c\uc801 \uc720\uc804\uc790\uc758 \ud2b9\uc774\uc801\uc778 \ubc1c\ud604\uc744 \uc99d\uac00\uc2dc\ud0a4\uace0, \uc5fc\uc99d\uc131 \uc5f0\uc1c4 \ub124\ud2b8\uc6cc\ud06c\ub97c \uc0dd\uc131\ud569\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud5c8\ud608\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/ischemia\">\uad6d\uc18c \ube48\ud608<\/a>\u00a0\ubc1c\uc0dd\ud558\ub2e4\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib84\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib84\"><span class=\"anchor-text\">[84]<\/span><\/a>. \ub530\ub77c\uc11c lncRNA-H19\ub294 \ub2e4\uc74c\uacfc \uac19\uc740 \uacbd\uc6b0\uc5d0 \uac15\ub825\ud55c \uc704\ud5d8 \uc2e0\ud638\uc785\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c CIRI\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/immunoreactive-insulin\">CIRI<\/a>\u00a0\ubc1c\uc0dd\ud558\uace0 H19\uc758 \uc5b5\uc81c\uac00 \uc7a0\uc7ac\uc801\uc77c \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uce58\ub8cc\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/therapeutic-procedure\">\uce58\ub8cc<\/a>\u00a0\ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc758 \uacbd\uc6b0\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib84\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib84\"><span class=\"anchor-text\">[84]<\/span><\/a>. \ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc774 \uac00\ub2a5\ud55c AIM2 \uc5fc\uc99d\ubcf5\ud569\uccb4 \ub9e4\uac1c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc5d0\uc11c lincRNA MEG3\/miR-485\/AIM2 \ucd95\uc740 CIRI \ub3d9\uc548 caspase1 \uc2e0\ud638 \uc804\ub2ec\uc744 \ud65c\uc131\ud654\ud558\uc5ec \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \ucd09\uc9c4\ud558\ubbc0\ub85c \uc774 \ucd95\uc740 \ub2e4\uc74c\uacfc \uac19\uc740 \ud6a8\uacfc\uc801\uc778 \uce58\ub8cc \ud45c\uc801\uc774 \ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c IS\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/brain-ischemia\">\uc774\ub2e4<\/a>\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib84\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib84\"><span class=\"anchor-text\">[84]<\/span><\/a>. \uc5d0 \ub300\ud55c\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uba74\uc5ed \uc870\uc808\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/immunoregulation\">\uba74\uc5ed \uc870\uc808<\/a>\u00a0\uc18c\uad50\uc138\ud3ec\uc758 Wang et al. LncRNA-Fendrr\uc774\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc720\ube44\ud034\ud2f4\ud654\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/ubiquitination\">\uc720\ube44\ud034\ud2f4\ud654<\/a>\u00a0HERC2\ub97c \ud1b5\ud55c NLRC4 \ub2e8\ubc31\uc9c8 \ubd84\ud574 \ubc0f \uc18c\uad50\uc138\ud3ec \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uc870\uc808\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib85\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib85\"><span class=\"anchor-text\">[85]<\/span><\/a>. Zhang et al. lncRNA NEAT1\/miR-22-3p \ucd95\uc774 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc5b5\uc81c\ud558\uace0 CIRI \uc190\uc0c1\uc744 \uc57d\ud654\uc2dc\ud0a4\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib86\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib86\"><span class=\"anchor-text\">[86]<\/span><\/a>. IS \ud6c4 \uc2dc\ud5d8\uad00 \ub0b4 \uc0b0\uc18c-\ud3ec\ub3c4\ub2f9 \uacb0\ud54d(OGD) \uc190\uc0c1 \uc2e4\ud5d8\uc5d0\uc11c\ub294 OGD\uac00 NOD \uc720\uc0ac \uc218\uc6a9\uccb4 \ub2e8\ubc31\uc9c8 3(NLRP3) \ubc1c\ud604\uc744 \uc99d\uac00\uc2dc\ucf1c NSC\uc758 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uc0ac\ub9dd\uc744 \uc720\ub3c4\ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uace0\uc555 \uc0b0\uc18c \uc694\ubc95\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/hyperbaric-medicine\">\uace0\uc555\uc0b0\uc18c\uce58\ub8cc<\/a>. \uc0c1\ud5a5\uc870\uc808\ub41c lncRNA-H19\ub294 miR-423-5p\uc758 \ubd84\uc790 \uc2a4\ud380\uc9c0 \uc5ed\ud560\uc744 \ud558\uba70, OGD \uc774\ud6c4 NLRP3\ub97c \ud45c\uc801\uc73c\ub85c \uc0bc\uc544 \uc2e0\uacbd\uc904\uae30\uc138\ud3ec(NSC) \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc720\ub3c4\ud569\ub2c8\ub2e4. \ub530\ub77c\uc11c \uace0\uc555\uc0b0\uc18c\uc694\ubc95\uc740 lncRNA-H19\/miR-423-5p\/NLRP3 \ucd95\uc744 \uc5b5\uc81c\ud558\uc5ec NSC\ub97c \ubc1c\uc5f4\uc99d\uc73c\ub85c\ubd80\ud130 \ubcf4\ud638\ud55c\ub2e4\ub294 \uac83\uc774 \ud655\uc778\ub418\uc5c8\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib87\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib87\"><span class=\"anchor-text\">[87]<\/span><\/a>. miR-21\uc740\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c microRNA\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/microrna\">\ub9c8\uc774\ud06c\ub85cRNA<\/a>\u00a0(miRNA)\ub294 \ubc1c\uc5f4\uc99d \ubc1c\uc0dd\uacfc \ubc00\uc811\ud55c \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 miR-21\uc740 NLRP3 \ub2e8\ubc31\uc9c8\uc744 \ud2b9\uc774\uc801\uc73c\ub85c \uc870\uc808\ud558\uace0, NLRP3 \ub2e8\ubc31\uc9c8\uc744 \ud65c\uc131\ud654\ud558\uace0, NLRP3 \ubd84\ube44\ub97c \uc790\uadf9\ud558\uace0, \uc5fc\uc99d \ud53c\ub4dc\ubc31 \uacbd\ub85c\ub97c \ud1b5\ud55c NF-\u03baB \uc2e0\ud638 \uc804\ub2ec\uc744 \ud1b5\ud574 \ub300\uc2dd\uc138\ud3ec\uc5d0\uc11c \ubc1c\ud604\ud560 \uc218 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib88\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib88\"><span class=\"anchor-text\">[88]<\/span><\/a>. NLRP3 \ud65c\uc131\ud654 \uc678\uc5d0\ub3c4 miR-21\uc740 \ub2e4\uc6b4\uc2a4\ud2b8\ub9bc \uce74\uc2a4\ud30c\uc81c-1\uc758 \ud65c\uc131\ud654\ub97c \uc870\uc808\ud558\uace0 IL-1\u03b2\uc758 \ubd84\ube44\ub97c \ucd09\uc9c4\ud558\uba70 \ubc1c\uc5f4\uc99d\uc758 \ubc1c\uc0dd\uc744 \ucd09\uc9c4\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. miR-21\uc774 \uacb0\ud54d\ub418\uba74 NLRP3\uc5d0 \uc758\ud574 \uc870\uc808\ub418\ub294 \uce74\uc2a4\ud30c\uc81c-1 \uacbd\ub85c\uc758 \ubc1c\ud604\uc774 \ud06c\uac8c \uac10\uc18c\ud569\ub2c8\ub2e4. \ub530\ub77c\uc11c miR-21\uc758 \ubc1c\ud604 \uc218\uc900\uc740 \ubc1c\uc5f4\uc99d\uc758 \ubc1c\uc0dd\uc744 \uc870\uc808\ud558\ub294 \ud575\uc2ec \uc5f0\uacb0 \uace0\ub9ac\uc774\uae30\ub3c4 \ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib89\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib89\"><span class=\"anchor-text\">[89]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib90\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib90\"><span class=\"anchor-text\">[90]<\/span><\/a>. \ud604\ub300 \ubd84\uc790 \uc0dd\ubb3c\ud559 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 miR-214-3p\uc5d0\ub294 \uce74\uc2a4\ud30c\uc81c-1\uc758 \uacb0\ud569 \ubd80\uc704\uac00 \uc788\uc73c\uba70, \uc774\ub294 \uce74\uc2a4\ud30c\uc81c-1\uc758 \ubc1c\uc0dd\uc5d0 \ud2b9\uc774\uc801\uc73c\ub85c \uacb0\ud569\ud558\uc5ec \uc5fc\uc99d \ubc18\uc751\uc744 \uc870\uc808\ud558\uace0 \ubc1c\uc5f4\uc99d\uc758 \ubc1c\uc0dd\ub960\uc744 \uc99d\uac00\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib91\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib91\"><span class=\"anchor-text\">[91]<\/span><\/a>.<\/p>\n<div>\n<p id=\"p0065\">pyroptosis\uc758 \ubd84\uc790 \uba54\ucee4\ub2c8\uc998\uc740 \ub2e4\uc74c\uacfc \uac19\uc774 \uc694\uc57d\ub418\uc5c8\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#fig0005\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"fig0005\"><span class=\"anchor-text\">\uadf8\ub9bc 1<\/span><\/a>.<\/p>\n<figure id=\"fig0005\" class=\"figure text-xs\"><img decoding=\"async\" src=\"https:\/\/ars.els-cdn.com\/content\/image\/1-s2.0-S0753332222013889-gr1.jpg\" alt=\"Fig. 1\" height=\"414\" aria-describedby=\"cap0005\" \/><\/p>\n<ol class=\"u-margin-s-bottom\">\n<li><a class=\"anchor download-link u-font-sans u-display-inline anchor-default\" title=\"\uace0\ud574\uc0c1\ub3c4 \uc774\ubbf8\uc9c0 \ub2e4\uc6b4\ub85c\ub4dc(294KB)\" href=\"https:\/\/ars.els-cdn.com\/content\/image\/1-s2.0-S0753332222013889-gr1_lrg.jpg\" target=\"_blank\" rel=\"noopener\" download=\"\"><span class=\"anchor-text\">\ub2e4\uc6b4\ub85c\ub4dc :\u00a0<span class=\"download-link-title\">\uace0\ud574\uc0c1\ub3c4 \uc774\ubbf8\uc9c0 \ub2e4\uc6b4\ub85c\ub4dc(294KB)<\/span><\/span><\/a><\/li>\n<li><a class=\"anchor download-link u-font-sans u-display-inline anchor-default\" title=\"\uc804\uccb4 \ud06c\uae30 \uc774\ubbf8\uc9c0 \ub2e4\uc6b4\ub85c\ub4dc\" href=\"https:\/\/ars.els-cdn.com\/content\/image\/1-s2.0-S0753332222013889-gr1.jpg\" target=\"_blank\" rel=\"noopener\" download=\"\"><span class=\"anchor-text\">\ub2e4\uc6b4\ub85c\ub4dc :\u00a0<span class=\"download-link-title\">\uc804\uccb4 \ud06c\uae30 \uc774\ubbf8\uc9c0 \ub2e4\uc6b4\ub85c\ub4dc<\/span><\/span><\/a><\/li>\n<\/ol>\n<p id=\"sp0005\"><span class=\"label\">\uadf8\ub9bc 1<\/span>. \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc758 \ubd84\uc790 \uba54\ucee4\ub2c8\uc998(\ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc758 \uba54\ucee4\ub2c8\uc998\uc5d0\ub294 \ud45c\uc900 \uc5fc\uc99d\ubcf5\ud569\uccb4 \uacbd\ub85c\uc640 \ube44\uc815\uaddc \uc5fc\uc99d\ubcf5\ud569\uccb4 \uacbd\ub85c\uac00 \ud3ec\ud568\ub429\ub2c8\ub2e4. \ud45c\uc900 \uc5fc\uc99d\ubcf5\ud569\uccb4 \uacbd\ub85c\ub294 DAMP \ub610\ub294 PAMP\uc5d0 \uc758\ud574 \uc720\ubc1c\ub429\ub2c8\ub2e4. \ube44\uc815\uaddc \uc5fc\uc99d\ubcf5\ud569\uccb4 \uacbd\ub85c\ub294 \uc138\ud3ec\uc678 \uadf8\ub78c \uc74c\uc131 \ubc15\ud14c\ub9ac\uc544\uc758 LPS\uc5d0 \uc758\ud574 \uc720\ubc1c\ub429\ub2c8\ub2e4. \ub610\ub294 \uc0ac\ub9dd \uc790\uadf9. \uc720\ubc1c \ud6c4, \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub294 \uc77c\ub828\uc758 \ubd84\uc790\uac04 \uc0c1\ud638\uc791\uc6a9\uc744 \ud1b5\ud574 \uc720\ubc1c\ub429\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c TLR\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/toll-like-receptor\">TLR<\/a>: \uc720\ub8cc \uc720\uc0ac \uc218\uc6a9\uccb4; GSDM: \uadf8\uc2a4\ub370\ub974\ubbfc; NLRP3: \ub274\ud074\ub808\uc624\ud2f0\ub4dc \uacb0\ud569 \uc62c\ub9ac\uace0\uba38\ud654 \ub3c4\uba54\uc778 \uc720\uc0ac \uc218\uc6a9\uccb4\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c pyrin \ub3c4\uba54\uc778\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/pyrin-domain\">\ud53c\ub9b0 \ub3c4\uba54\uc778<\/a>\u00a03\uac1c \ud568\uc720; DAMP: \uc190\uc0c1\uacfc \uad00\ub828\ub41c \ubd84\uc790 \ud328\ud134; PAMP: \ubcd1\uc6d0\uccb4 \uad00\ub828 \ubd84\uc790 \ud328\ud134).<\/p>\n<\/figure>\n<\/div>\n<\/section>\n<section id=\"sec0045\">\n<h3 id=\"sect0065\" class=\"u-h4 u-margin-m-top u-margin-xs-bottom\">2.4. \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc640 \ub2e4\ub978 \uc138\ud3ec \uc190\uc0c1 \uc0ac\uc774\uc758 \uad00\uacc4<\/h3>\n<p id=\"p0070\">\ub1cc\ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc758 \ubc1c\uc0dd\uc5d0\ub294 \ub2e4\uc591\ud55c \uba54\ucee4\ub2c8\uc998\uc774 \uad00\uc5ec\ud569\ub2c8\ub2e4. \uc54c\ub824\uc9c4 \uba54\ucee4\ub2c8\uc998\uc740 \uc5fc\uc99d \ubc18\uc751, \uce7c\uc298 \ucc44\ub110 \uc7a5\uc560, \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uae30\ub2a5 \uc190\uc0c1 \ubc0f \uc790\uac00\ud3ec\uc2dd\uacfc \uac19\uc740 \ub2e4\uc591\ud55c \uba54\ucee4\ub2c8\uc998\uacfc \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4. Pyroptosis\ub294 \ub1cc\ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc758 \ubaa8\ub4e0 \uce21\uba74\uc5d0 \uad00\uc5ec\ud558\uba70 \ub2e4\ub978 \uc190\uc0c1\uacfc \ubc00\uc811\ud558\uac8c \uad00\ub828\ub418\uc5b4 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<p id=\"p0075\">pyroptosis\uc640 apoptosis\uc758 \ubc1c\uc0dd\uc740 \ubaa8\ub450 \uc138\ud3ec \uc0ac\uba78\uc758 \ud55c \ubc29\uc2dd\uc5d0 \uc18d\ud558\uc9c0\ub9cc \uadfc\ubcf8\uc801\uc73c\ub85c \ub2e4\ub985\ub2c8\ub2e4. \uc544\ud3fd\ud1a0\uc2dc\uc2a4\ub294 \uc138\ud3ec \uc0ac\uba78\uc758 \uc0dd\ub9ac\ud559\uc801 \ubc29\ubc95\uc778 \ubc18\uba74, \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub294 \uc885\uc885 \uc2e0\uccb4 \uc190\uc0c1 \ud6c4 \ubcd1\ub9ac\ud559\uc801 \uc138\ud3ec \uc0ac\uba78\uacfc \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib92\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib92\"><span class=\"anchor-text\">[92]<\/span><\/a>. \uc790\uac00\ud3ec\uc2dd\uc740 \ub110\ub9ac \uc874\uc7ac\ud558\ub294 \uc790\uac00\ud3ec\uc2dd \ud604\uc0c1\uc758 \uc77c\uc885\uc785\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc9c4\ud575 \uc138\ud3ec\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/eukaryotic-cell\">\uc9c4\ud575 \uc138\ud3ec<\/a>. \uc790\uac00\ud3ec\uc2dd\uc740 \uc77c\ubc18\uc801\uc73c\ub85c \uc0e4\ud398\ub860 \ub9e4\uac1c \uc790\uac00\ud3ec\uc2dd, \ubbf8\uc138\uc790\uac00\ud3ec\uc2dd, \uac70\ub300\uc790\uac00\ud3ec\uc2dd\uc758 \uc138 \uac00\uc9c0 \uc720\ud615\uc73c\ub85c \uad6c\ubd84\ub429\ub2c8\ub2e4. \ud604\uc7ac \uac70\ub300\uc790\uac00\ud3ec\uc2dd\uc5d0 \uad00\ud55c \ub9ce\uc740 \uc5f0\uad6c\uac00 \uc9c4\ud589\ub418\uace0 \uc788\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib93\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib93\"><span class=\"anchor-text\">[93]<\/span><\/a>. \uc790\uac00\ud3ec\uc2dd\uc740 \uc138\ud3ec\uc758 \uc815\uc0c1\uc801\uc778 \ub300\uc0ac \uacfc\uc815\uc5d0 \uc5c6\uc5b4\uc11c\ub294 \uc548 \ub420 \ubd80\ubd84\uc785\ub2c8\ub2e4. \uc790\uac00\ud3ec\uc2dd\uc744 \uc5b5\uc81c\ud558\uba74 \uc870\uc9c1, \uae30\uad00 \ub610\ub294 \uc138\ud3ec\uc5d0 \uc720\ud574 \ubb3c\uc9c8\uc774 \ucd95\uc801\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc790\uac00\ud3ec\uc2dd\uc758 \uacfc\ub3c4\ud55c \ud65c\uc131\ud654\ub294 \uc911\uc694\ud55c \uc138\ud3ec\ub0b4 \uc18c\uae30\uad00\uacfc \ud544\uc218 \ub2e8\ubc31\uc9c8\uc744 \ud30c\uad34\ud558\uc5ec \uc790\uac00\ud3ec\uc2dd \uc138\ud3ec\uc0ac\uba78\uc744 \uc720\ubc1c\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib94\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib94\"><span class=\"anchor-text\">[94]<\/span><\/a>.<\/p>\n<p id=\"p0080\">\ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc640 \uc790\uac00\ud3ec\uc2dd\uc740 \ubd88\uac00\ubd84\uc758 \uad00\uacc4\uc5d0 \uc788\uc2b5\ub2c8\ub2e4. \uc815\uc0c1\uc801\uc778 \uc0c1\ud669\uc5d0\uc11c \uc0dd\uccb4 \ub0b4 \uc790\uac00\ud3ec\uc2dd\uacfc \ubc1c\uc5f4\uc99d\uc758 \ubc1c\uc0dd\uc740 \ub3d9\uc801 \ud3c9\ud615 \uc0c1\ud0dc\uc5d0 \uc788\uc2b5\ub2c8\ub2e4. \uc2e0\uccb4\uac00 \uc678\ubd80 \uc790\uadf9\uc5d0 \ub300\ud55c \uc5fc\uc99d \ubc18\uc751\uc744 \uc77c\uc73c\ud0a4\uba74 \uc790\uac00\ud3ec\uc2dd\uacfc \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uc0ac\uc774\uc758 \uade0\ud615\uc774 \uae68\uc9d1\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib95\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib95\"><span class=\"anchor-text\">[95]<\/span><\/a>. \uc608\ub97c \ub4e4\uc5b4 NF-\u03baB\ub294\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc2e0\ud638 \ubcc0\ud658 \uacbd\ub85c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/signal-transduction-pathway\">\uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c<\/a>\u00a0\ub9ce\uc740 \uc2e0\ud638 \uc804\ub2ec\uc5d0 \ucc38\uc5ec\ud558\ub294\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc2e0\ud638 \uacbd\ub85c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/cell-signaling-pathway\">\uc2e0\ud638 \uacbd\ub85c<\/a>\u00a0\uc2e0\ud638 \ubcc0\ud658\uc744 \ub2ec\uc131\ud558\uae30 \uc704\ud574. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 NF-\u03baB \uc720\uc804\uc790\uac00 \ub179\uc544\uc6c3\ub41c IS \ub9c8\uc6b0\uc2a4\uc5d0\uc11c\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c mTOR\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/mammalian-target-of-rapamycin\">mTOR<\/a>\u00a0\ud65c\ub3d9\uc774 \uc5b5\uc81c\ub418\uace0 \uc790\uac00\ud3ec\uc2dd \uc218\uc900\uc774 \ud5a5\uc0c1\ub418\uc5c8\uc2b5\ub2c8\ub2e4. NF-\u03baB\uc758 \uc2e0\ud638\uc804\ub2ec \ud65c\uc131\ud654 \uacbd\ub85c\ub294 NF-\u03baB \uc720\ub3c4 \ud0a4\ub098\uc81c\ub97c \ud65c\uc131\ud654\uc2dc\ud0a4\ub294 \ub2e4\uc218\uc758 \uc790\uadf9\uc73c\ub85c I\u03baK\u03b1, I\u03baKB \ubc0f I\u03baK\u03b3 \uc0bc\ub7c9\uccb4\ub97c \ud65c\uc131\ud654\uc2dc\ucf1c I\u03baB\uc758 \uc778\uc0b0\ud654 \ubc0f \ubd84\ud574\ub97c \uc77c\uc73c\ud0a4\uace0 \ucd5c\uc885\uc801\uc73c\ub85c NF-\u03baB \uc2e0\ud638\uc804\ub2ec \uacbd\ub85c\ub97c \ud65c\uc131\ud654\uc2dc\ud0b5\ub2c8\ub2e4. . \ud65c\uc131\ud654 \ud6c4 NF-\u03baB\ub294 \uc138\ud3ec\uc5d0 \ub4e4\uc5b4\uac00 \ud574\ub2f9 DNA \uc218\uc6a9\uccb4\uc5d0 \ud2b9\uc774\uc801\uc73c\ub85c \uacb0\ud569\ud558\uc5ec \uc5fc\uc99d \uc778\uc790\uc758 \uc804\uc0ac\ub97c \uc790\uadf9\ud558\uace0 \uc5fc\uc99d \uc778\uc790 TNF-\u03b1, IL-1\u03b2 \ubc0f IL-6\uc758 \ub300\ub7c9 \ubc1c\ud604\uc744 \ucd09\uc9c4\ud569\ub2c8\ub2e4. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 NF-\u03baB \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub294 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc720\ubc1c\ud558\ub294 \uc8fc\uc694 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \ub2e8\ubc31\uc9c8 NLRP3\uc758 \uc804\uc0ac \uc804 \ubc0f \uc804\uc0ac \ud6c4 \uc218\uc900\uc758 \ud65c\uc131\ud654\ub97c \uc870\uc808\ud558\ub294 \ub370 \uad00\uc5ec\ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \ud48d\ubd80\ud558\uac8c \ubc1c\ud604\ub418\ub294 \uc5fc\uc99d\uc778\uc790\ub294 \uccb4\ub0b4\uc5d0\uc11c \uc5fc\uc99d \uc5f0\uc1c4\ubc18\uc751\uc744 \uc77c\uc73c\ud0a4\uace0, \ubc1c\uc5f4\uc99d\uc744 \uc720\ubc1c\ud558\uba70, \uc5fc\uc99d \ubc18\uc751\uc744 \ub354\uc6b1 \ud655\uc7a5\uc2dc\ucf1c \ub1cc\uc190\uc0c1\uc744 \uc545\ud654\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib96\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib96\"><span class=\"anchor-text\">[96]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib97\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib97\"><span class=\"anchor-text\">[97]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib98\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib98\"><span class=\"anchor-text\">[98]<\/span><\/a>.<\/p>\n<\/section>\n<section id=\"sec0050\">\n<h3 id=\"sect0070\" class=\"u-h4 u-margin-m-top u-margin-xs-bottom\">2.5. IS\uc640 \uad00\ub828\ub41c \ubc1c\uc5f4\uc99d \ubc0f \uc5fc\uc99d\uc758 \uba54\ucee4\ub2c8\uc998<\/h3>\n<p id=\"p0085\">\uc5fc\uc99d\uc131 \uc5f0\uc1c4\ubc18\uc751\uc740 IS\uc758 \ub2e4\uc591\ud55c \ub2e8\uacc4\uc5d0 \uc874\uc7ac\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib99\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib99\"><span class=\"anchor-text\">[99]<\/span><\/a>. IS\uc758 \ucd08\uae30 \ub2e8\uacc4\uc5d0\uc11c\ub294 \ub1cc\uc758 \ud608\ub958\uac00 \ub290\ub824\uc9c0\uace0\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud638\uc911\uad6c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/neutrophil\">\ud638\uc911\uad6c<\/a>\u00a0~\uc744 \uace0\uc218\ud558\ub2e4\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub0b4\ud53c \uc138\ud3ec\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/endothelial-cell\">\ub0b4\ud53c \uc138\ud3ec<\/a>\u00a0\ud5c8\ud608\uc131 \ud608\uad00\uc774 \ud30c\uad34\ub418\uace0 \ucd08\uae30 \uae09\uc131 \uc5fc\uc99d \ubc18\uc751\uc774 \uc2dc\uc791\ub429\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib100\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib100\"><span class=\"anchor-text\">[100]<\/span><\/a>. \ub1cc\ud5c8\ud608 \ud6c4 \uc7ac\uad00\ub958\uac00 \ubc1c\uc0dd\ud558\uba74 \uc678\uc778\uc131 \uc5fc\uc99d\uc778\uc790, \uc5fc\uc99d\uc138\ud3ec \ubc0f \uc5fc\uc99d\uc778\uc790\uac00 \ud608\uc561\ub1cc\uad00\ubb38\uc744 \ud1b5\uacfc\ud558\uc5ec \uc7ac\uad00\ub958 \ud6c4 \ud5c8\ud608\uc758 2\ucc28\uc801\uc778 \uc601\ud5a5\uc744 \ubbf8\uce58\uac8c \ub418\uace0, \uc0b0\ud654\uc778\uc790\uc640 \uc0b0\ud654\uc778\uc790\uac00 \ub2e4\ub7c9\uc73c\ub85c \ubc29\ucd9c\ub418\uac8c \ub41c\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc790\uc720\ub77c\ub514\uce7c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/radical-chemistry\">\uc790\uc720 \ub77c\ub514\uce7c<\/a>. \uc774 \ub54c, \ubbf8\uc138\uc544\uad50\uc138\ud3ec\ub294\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub1cc \uc870\uc9c1\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/brain-tissue\">\ub1cc \uc870\uc9c1<\/a>\u00a0\uc810\ucc28\uc801\uc73c\ub85c \ub300\ub7c9\uc73c\ub85c \ud65c\uc131\ud654\ub418\uc5b4 \ub354 \ub9ce\uc774 \uc0dd\uc0b0\ub429\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc5fc\uc99d \ub9e4\uac1c\uccb4\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/inflammatory-mediator\">\uc5fc\uc99d \ub9e4\uac1c\uccb4<\/a>. \uc774\ub7ec\ud55c \uc720\ud615\uc758 \uc5fc\uc99d \ub9e4\uac1c\uccb4\ub294 \ub1cc \uc870\uc9c1\uc758 \ub0b4\ud53c \uc138\ud3ec\ub97c \uacfc\ub3c4\ud558\uac8c \ud65c\uc131\ud654\ud558\uace0 \ub2e4\ub7c9\uc758 \uc5fc\uc99d \ub9e4\uac1c\uccb4\ub97c \uc0dd\uc131\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc870\uc9c1 \uc778\uc790\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/thromboplastin\">\uc870\uc9c1 \uc778\uc790<\/a>\u00a0\uc544\ubbf8\ub178\uc0b0\uc758 \ub3c5\uc131\uc744 \ucd95\uc801\ud569\ub2c8\ub2e4. \uc774\ub294 \uc0b0\ud654 \uc778\uc790, \uc790\uc720 \ub77c\ub514\uce7c\uc758 \ubc29\ucd9c\uc744 \ub354\uc6b1 \uc545\ud654\uc2dc\ud0b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc77c\uc0b0\ud654\ud0c4\uc18c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/carbon-monoxide\">\uc77c\uc0b0\ud654\ud0c4\uc18c<\/a>NF-\u03baB, Toll \uc720\uc0ac \uc218\uc6a9\uccb4 \ubc0f Nod \uc720\uc0ac \uc218\uc6a9\uccb4(NLR)\uc640 \uac19\uc740 \uc5fc\uc99d \ubc18\uc751 \uad00\ub828 \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub97c \ud65c\uc131\ud654\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib101\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib101\"><span class=\"anchor-text\">[101]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib102\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib102\"><span class=\"anchor-text\">[102]<\/span><\/a>. \uc608\ub97c \ub4e4\uc5b4, NLR\uc5d0 \ub300\ud55c \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 NLR\uc5d0\ub294 23\uac1c\uc758 \uacc4\uc5f4 \uad6c\uc131\uc6d0\uc774 \uc788\uc73c\uba70 \uc8fc\ub85c \uc138\ud3ec\uc9c8\uc5d0\uc11c \ubc1c\ud604\ub418\uace0 \uc2e0\uccb4\uc758 \uc120\ucc9c\uc801 \uba74\uc5ed \ubc18\uc751\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. NLR \uacc4\uc5f4\uc778 Nalp1, Nalp3, Nalp5 \ubc0f Ipaf\uc758 \uad6c\uc131\uc6d0\uc740 \ub2e4\uc74c\uc744 \ud1b5\ud574 \uce74\uc2a4\ud30c\uc81c-1 \ud65c\uc131\ud654\ub97c \ud65c\uc131\ud654\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc5b4\ub311\ud130 \ub2e8\ubc31\uc9c8\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/adaptor-protein\">\uc5b4\ub311\ud130 \ub2e8\ubc31\uc9c8<\/a>\u00a0ASC\ub294 \uc77c\ub828\uc758 \uc5fc\uc99d \ubc18\uc751\uc744 \uc2dc\uc791\ud558\uace0 \ubc1c\uc5f4\uc99d\uc744 \uc911\uc7ac\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib103\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib103\"><span class=\"anchor-text\">[103]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib104\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib104\"><span class=\"anchor-text\">[104]<\/span><\/a>. NLRP3\ub294 \uc5fc\uc99d \uc778\uc790\uc758 \uc911\uc694\ud55c \uad6c\uc131 \uc694\uc18c\uc785\ub2c8\ub2e4. NLRP3\uc5d0\ub294 PYD, NACHT, LRR\uc758 \uc138 \uac00\uc9c0 \ub3c4\uba54\uc778\uc774 \ud3ec\ud568\ub418\uc5b4 \uc788\uc73c\uba70 \uc774\ub294 LRR-NACHT-PYD: PYD-CARD: CARD-CARDC spase \ub3c4\uba54\uc778\uc73c\ub85c \ud45c\uc2dc\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub294 \ub0b4\uc778\uc131 \uc190\uc0c1\uc758 \ub2e4\uc591\ud55c \uc2e0\ud638\uc5d0 \ubc18\uc751\ud558\ubbc0\ub85c NLRP3 \uc778\ud50c\ub77c\ub9c8\uc880\uc758 \ud65c\uc131\ud654\uac00 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc758 \uc8fc\uc694 \uc720\ud615\uc73c\ub85c \uac04\uc8fc\ub429\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib105\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib105\"><span class=\"anchor-text\">[105]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib106\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib106\"><span class=\"anchor-text\">[106]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib107\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib107\"><span class=\"anchor-text\">[107]<\/span><\/a>.<\/p>\n<p id=\"p0090\">\uc778\ud50c\ub77c\ub9c8\uc19c\uc740 \uc2e0\uccb4\uac00 \uac10\uc5fc\uc774\ub098 \uc138\ud3ec \uc190\uc0c1 \uc2e0\ud638\ub97c \ubc1b\uc740 \ud6c4 \uc870\ub9bd\ub41c \ub2e8\ubc31\uc9c8 \ubcf5\ud569\uccb4\uc774\uba70, \ud504\ub85c\uce74\uc2a4\ud30c\uc81c-1\uc758 \ubaa8\uc9d1 \ubc0f \ud65c\uc131\ud654\ub97c \uc704\ud55c \ud50c\ub7ab\ud3fc \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \ud504\ub85c\ubaa8\ud130 \ub2e8\ubc31\uc9c8 NLRP3\uc740 \uc5fc\uc99d\ubcf5\ud569\uccb4 \uc5b4\ub311\ud130 \ubd84\uc790 ASC\ub97c \uc0ac\uc6a9\ud55c \uc62c\ub9ac\uace0\uba38\ud654\ub97c \ud1b5\ud574 \ub2e4\ub7c9\uc758 \ud504\ub85c\uce74\uc2a4\ud30c\uc81c-1\uc744 \ubaa8\uc9d1\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib108\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib108\"><span class=\"anchor-text\">[108]<\/span><\/a>. \ud504\ub85c\uce74\uc2a4\ud30c\uc81c-1\uc740 \uce74\uc2a4\ud30c\uc81c-1\uc758 \uc804\uad6c\uccb4\uc774\uba70, \ud65c\uc131 \uce74\uc2a4\ud30c\uc81c-1\uc740 \uc138\ud3ec\ub97c \ube60\ub974\uac8c \uc6a9\ud574\uc2dc\ucf1c \uc138\ud3ec\uc678 IL-1\u03b2 \ubc0f IL-18\uc744 \ud65c\uc131\ud654 \ubc0f \ubc29\ucd9c\ud558\ub294 \uc5ed\ud560\uc744 \ud558\uba70, \uc774\ub294 \uc5fc\uc99d \ubc18\uc751\uc744 \ub354\uc6b1 \uc545\ud654\uc2dc\ud0b5\ub2c8\ub2e4. \ub530\ub77c\uc11c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc758 \ubc1c\uc0dd\uc740 \uc5fc\uc99d \ubc18\uc751\uc758 \ucd9c\ud604 \ubc0f \uc778\ud50c\ub77c\ub9c8\uc19c\uc758 \ud615\uc131\uacfc \ubc00\uc811\ud55c \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4. \ub1cc\ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc758 \ubc1c\uc0dd\uc740 \ubc1c\uc5f4\uc99d\uacfc \uc5fc\uc99d \ubc18\uc751 \uc0ac\uc774\uc758 \uc0c1\ud638\uc791\uc6a9\uacfc \ub354 \ubc00\uc811\ud558\uac8c \uad00\ub828\ub418\uc5b4 \uc788\uc2b5\ub2c8\ub2e4\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib109\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib109\"><span class=\"anchor-text\">[109]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib110\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib110\"><span class=\"anchor-text\">[110]<\/span><\/a>. \ud2b9\ud788 \uc911\ucd94\uc2e0\uacbd\uacc4\uc5d0\uc11c\ub294 \uc131\uc0c1\uad50\uc138\ud3ec\uac00 \uc18c\uad50\uc138\ud3ec\uc758 \ud65c\uc131\ud654\uc640 \uc99d\uc2dd\uc744 \uc720\ub3c4\ud558\uace0 \uc218\ub9ce\uc740 \uc5fc\uc99d \ub9e4\uac1c\uccb4\ub97c \uc0dd\uc131\ud569\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc5fc\uc99d \ub9e4\uac1c\uccb4\ub294 \ub0b4\ud53c \uc138\ud3ec\ub97c \ud65c\uc131\ud654\ud558\uc5ec \ub2e4\uc591\ud55c \uc870\uc9c1 \uc778\uc790\ub97c \uc0dd\uc131\ud558\uace0 \ub3c5\uc131\uc744 \uc99d\uac00\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud765\ubd84\uc131 \uc544\ubbf8\ub178\uc0b0\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/excitatory-amino-acid\">\ud765\ubd84\uc131 \uc544\ubbf8\ub178\uc0b0<\/a>, \ucd9c\uc2dc\ub97c \ud64d\ubcf4\ud569\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc0b0\ud654\uc9c8\uc18c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/nitric-oxide\">\uc0b0\ud654\uc9c8\uc18c<\/a>\u00a0\uadf8\ub9ac\uace0 \uc0b0\uc18c \uc790\uc720 \ub77c\ub514\uce7c. \uc704\uc758 \ubb3c\uc9c8\uc740 NF-\u03baB \ubc0f JNK2\/STAT3\uc640 \uac19\uc740 \ub2e4\uc911 \uc5fc\uc99d \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\uc758 \ud65c\uc131\ud654\ub97c \uc720\ub3c4\ud558\uace0 NLRP1 \ubc0f NLRP3\uc640 \uac19\uc740 \uc5fc\uc99d\ubcf5\ud569\uccb4\uc758 \uc870\ub9bd\uc744 \ucd09\uc9c4\ud569\ub2c8\ub2e4. \ud65c\uc131\ud654\ub41c \uce74\uc2a4\ud30c\uc81c-1\uc740 \uc138\ud3ec\uc758 \uc5f4\ubd84\ud574\ub97c \uc720\ub3c4\ud558\uace0, \uc5fc\uc99d \ubc18\uc751\uc744 \ud655\uc7a5\uc2dc\ud0a4\uba70, \ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc744 \uc545\ud654\uc2dc\ud0b5\ub2c8\ub2e4\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib111\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib111\"><span class=\"anchor-text\">[111]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib112\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib112\"><span class=\"anchor-text\">[112]<\/span><\/a>. \uc77c\ubd80 \uc5f0\uad6c\uc5d0\uc11c\ub294 \uc57c\uc0dd\ud615 \ub9c8\uc6b0\uc2a4\uc640 \ube44\uad50\ud558\uc5ec AIM2 \ub1cc\uc758 AIM2 \ubc0f IL-1\u03b2 \uc218\uc900\uc774 \ub354 \ub192\uc740 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub179\uc544\uc6c3 \ub9c8\uc6b0\uc2a4\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/knockout-mouse\">\ub179\uc544\uc6c3 \ub9c8\uc6b0\uc2a4<\/a>\u00a0\ub1cc\ud5c8\ud608-\uc7ac\uad00\ub958\uac00 \uc720\uc758\ud558\uac8c \uac10\uc18c\ud55c \ud6c4 \uacbd\uc0c9 \ubd80\ud53c\uac00 \uc720\uc758\ud558\uac8c \uac10\uc18c\ud588\uc73c\uba70\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc2e0\uacbd \uae30\ub2a5\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/nervous-system-physiology\">\uc2e0\uacbd \uae30\ub2a5<\/a>\u00a0\uc810\uc218\ub3c4 \ub208\uc5d0 \ub744\uac8c \uc88b\uc544\uc84c\uc2b5\ub2c8\ub2e4. AIM2 \uc778\ud50c\ub77c\ub9c8\uc19c \ud65c\uc131\ud654\ub97c \uc5b5\uc81c\ud558\uba74 \ubc1c\uc5f4\uc99d\uc758 \ubc1c\uc0dd\uc744 \uc5b4\ub290 \uc815\ub3c4 \uc5b5\uc81c\ud558\uc5ec \ud5c8\ud608\uc131 \ub1cc\uc190\uc0c1\uc744 \uc904\uc77c \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib113\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib113\"><span class=\"anchor-text\">[113]<\/span><\/a>. \uadf8\ub7ec\ubbc0\ub85c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub294 \ub1cc\ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1 \uacfc\uc815\uc5d0\uc11c \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud55c\ub2e4. NLRP3 \uc778\ud50c\ub77c\ub9c8\uc880\uc740 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uacbd\ub85c\uc758 \ud575\uc2ec \ub2e8\ubc31\uc9c8\uc774\uba70, \uc774\uc758 \ubc1c\ud604\uc744 \uc5b5\uc81c\ud558\uba74 \ud558\ub958 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uacbd\ub85c \uad00\ub828 \ub2e8\ubc31\uc9c8\uc758 \ubc1c\ud604\uc744 \ub3d9\uc2dc\uc5d0 \uc5b5\uc81c\ud558\uace0 \uc5fc\uc99d \ubc18\uc751\uc744 \uc81c\ud55c\ud558\uba70 \ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc744 \uc644\ud654\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/section>\n<section id=\"sec0055\">\n<h3 id=\"sect0075\" class=\"u-h4 u-margin-m-top u-margin-xs-bottom\">2.6. Pyroptosis\uc640 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc190\uc0c1\uc740 IS \ud6c4 \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4 \uc190\uc0c1\uc744 \uc911\uc7ac\ud569\ub2c8\ub2e4<\/h3>\n<p id=\"p0095\">\ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\ub294 \uc8fc\ub85c \uc138\ud3ec\uc758 \ud638\uae30\uc131 \ud638\ud761\uc5d0 \uad00\uc5ec\ud558\uba70 \ud638\uae30\uc131 \ud638\ud761\uc774 \uc77c\uc5b4\ub098\ub294 \uacf3\uc785\ub2c8\ub2e4. \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\ub294 \uc138\ud3ec \uac04 \uc815\uc0c1\uc801\uc778 \uc2e0\ud638 \uc804\ub2ec\uacfc \uc2e0\uacbd \uc138\ud3ec\uc758 \uc2e0\ud638 \uc804\ub2ec\uc744 \uc704\ud55c \uc774\uc628\ud654\ub41c \uae30\ubc18\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib114\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib114\"><span class=\"anchor-text\">[114]<\/span><\/a>. \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc190\uc0c1\uc740 \ub300\ubd80\ubd84 \ube44\uc815\uc0c1\uc801\uc778 \uc6d0\uc778\uc73c\ub85c \uc778\ud574 \ubc1c\uc0dd\ud569\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ub300\uc0ac\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/mitochondrial-respiration\">\ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ub300\uc0ac<\/a>\u00a0\uadf8\ub9ac\uace0 \uc0b0\ud654\uc801 \uc190\uc0c1\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib115\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib115\"><span class=\"anchor-text\">[115]<\/span><\/a>. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc740 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uae30\ub2a5 \uc7a5\uc560\uc640 \ubc00\uc811\ud55c \uad00\ub828\uc774 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib116\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib116\"><span class=\"anchor-text\">[116]<\/span><\/a>. \uc0b0\ud654 \uc190\uc0c1 \ubc1c\uc0dd\uc758 \ud575\uc2ec\uc778 \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\ub294 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc640 \ubc00\uc811\ud55c \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib117\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib117\"><span class=\"anchor-text\">[117]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib118\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib118\"><span class=\"anchor-text\">[118]<\/span><\/a>. \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\ub294 \ub1cc \uc870\uc9c1 \uc190\uc0c1, \ud2b9\ud788 \ub1cc \ud5c8\ud608 \ubc0f \ub1cc \uc190\uc0c1\uc5d0\uc11c \ubc1c\ud604\ub420 \uac00\ub2a5\uc131\uc774 \ub354 \ub192\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc7ac\uad00\ub958 \uc190\uc0c1\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/reperfusion-injury\">\uc7ac\uad00\ub958 \uc190\uc0c1<\/a>\u00a0\ub1cc\ud5c8\ud608 \ud6c4\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib119\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib119\"><span class=\"anchor-text\">[119]<\/span><\/a>. \uc2e0\uccb4\uac00 \uc678\ubd80 \uc720\ud574\ubb3c\uc9c8\uc758 \uacf5\uaca9\uc744 \ubc1b\uc73c\uba74 \uc138\ud3ec\uc5d0\uc11c\ub294 \ub2e4\ub7c9\uc758\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c ROS\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/reactive-oxygen-species\">\ub85c\uc2a4<\/a>\u00a0\uadf8\ub9ac\uace0\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud65c\uc131\ud0c4\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/activated-charcoal\">\ud65c\uc131\ud0c4<\/a>, \uc774\ub294 \uc0b0\ud654\uc640 \ud56d\uc0b0\ud654 \uc0ac\uc774\uc758 \uade0\ud615\uc744 \ubb34\ub108\ub728\ub824 \uc77c\ub828\uc758 \uc0b0\ud654 \uc190\uc0c1 \ubc18\uc751\uc744 \uc77c\uc73c\ud0b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib120\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib120\"><span class=\"anchor-text\">[120]<\/span><\/a>. ROS\uc758 \ub300\ubd80\ubd84\uc740 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\uc5d0\uc11c \ubd84\ube44\ub429\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib121\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib121\"><span class=\"anchor-text\">[121]<\/span><\/a>. \uc678\ubd80 \uc790\uadf9\uc5d0 \uc758\ud574 \uc790\uadf9\uc744 \ubc1b\uac70\ub098 \ub0b4\uc778\uc131 \uc190\uc0c1\uc774 \ubc1c\uc0dd\ud558\uba74 \uc2e0\uccb4\ub294 \ub192\uc740 \uc218\uc900\uc758 ROS\ub97c \uc720\ub3c4\ud558\uc5ec \uc778\ud50c\ub77c\ub9c8\uc19c \ub2e8\ubc31\uc9c8 \ubcf5\ud569\uccb4\ub97c \ud65c\uc131\ud654\ud568\uc73c\ub85c\uc368 \ub274\ud074\ub808\uc624\ud2f0\ub4dc\uc640 NLRP3\uc758 \uacb0\ud569\uc744 \uc790\uadf9\ud569\ub2c8\ub2e4. ROS\uac00 \uacfc\ub3c4\ud558\uac8c \ud65c\uc131\ud654\ub418\uba74 \uc2e0\uccb4 \ub0b4 \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\uc758 \uc815\uc0c1\uc801\uc778 \uc21c\uc11c\uac00 \uc911\ub2e8\ub418\uc5b4 \uc138\ud3ec \ub0b4 \uc720\uc804 \ubb3c\uc9c8, \ub2e8\ubc31\uc9c8 \ubc0f \ub2e4\uc591\ud55c \uc138\ud3ec \uc18c\uae30\uad00(\ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ud3ec\ud568)\uc774 \ud30c\uad34\ub429\ub2c8\ub2e4. \uc138\ud3ec \ub0b4 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ub4f1 \ub2e4\uc591\ud55c \uc18c\uae30\uad00\uc774 \uc190\uc0c1\ub418\uba74 \uc138\ud3ec\uc758 \uc601\uc591\uacfc \ub300\uc0ac\uc5d0 \uc774\uc0c1\uc774 \uc0dd\uae30\uace0, ROS\ub294 \uc138\ud3ec\uc758 \uc190\uc0c1\uc744 \ub354\uc6b1 \uc545\ud654\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud608\uad00 \ub0b4\ud53c\uc138\ud3ec\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/vascular-endothelium\">\ud608\uad00 \ub0b4\ud53c<\/a>\u00a0\uadf8\ub9ac\uace0 \uad50\ub780\uc744 \uc720\ub3c4\ud55c\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ubbf8\uc138\uc21c\ud658\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/microcirculation\">\ubbf8\uc138 \uc21c\ud658<\/a>\u00a0\ub1cc\uc5d0\uc11c. \ub1cc\uc758 \ud608\uc561\ub1cc\uc7a5\ubcbd \ud22c\uacfc\uc131 \uc7a5\uc560\ub85c \uc778\ud574\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc138\ud3ec \uc811\ucc29 \ubd84\uc790\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/cell-adhesion-molecule\">\uc138\ud3ec \uc811\ucc29 \ubd84\uc790<\/a>, \uc774\ub85c \uc778\ud574 \ub1cc \uc190\uc0c1\uc774 \uc545\ud654\ub429\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib122\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib122\"><span class=\"anchor-text\">[122]<\/span><\/a>. \uadf8 \ub3d9\uc548\uc5d0,\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/oxidative-stress\">\uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4<\/a>\u00a0\uc138\ud3ec\uac00 \uc810\ucc28 \uc99d\uac00\ud558\ub294 \uac83\uc744 \ud2b9\uc9d5\uc73c\ub85c \ud558\ub294 \uc138\ud3ec \uc0ac\uba78 \ubaa8\ub4dc\ub97c \ub098\ud0c0\ub0c5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc138\ud3ec\ub9c9 \ud22c\uacfc\uc131\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/cell-membrane-permeability\">\uc138\ud3ec\ub9c9 \ud22c\uacfc\uc131<\/a>\u00a0\ubc0f \uc138\ud3ec \ub0b4\uc6a9\ubb3c\uc758 \ubc29\ucd9c \u2013 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib120\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib120\"><span class=\"anchor-text\">[120]<\/span><\/a>. \ub530\ub77c\uc11c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc640 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc190\uc0c1\uc740 \ubaa8\ub450 \ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc758 \ubcd1\ub9ac\ud559\uc801 \uacfc\uc815\uc5d0 \uad00\uc5ec\ud569\ub2c8\ub2e4. \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc6b4\ub3d9\uc131 \uad00\ub828 \ub2e8\ubc31\uc9c8 Drp1\uc740 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\uac00 \uc815\uc0c1\uc801\uc778 \uc0dd\ub9ac\uc801 \uae30\ub2a5\uc744 \uc720\uc9c0\ud558\ub294 \ub370 \ud544\uc694\ud55c \ud575\uc2ec \ub2e8\ubc31\uc9c8\uc778 \uac83\uc73c\ub85c \ubcf4\uace0\ub418\uc5c8\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib123\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib123\"><span class=\"anchor-text\">[123]<\/span><\/a>. Drp1\uc758 \ubc1c\ud604\uc774 \uc99d\uac00\ud558\uba74 \ub2e4\uc74c\uc744 \uc5b5\uc81c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ud575\ubd84\uc5f4\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/mitochondrial-fission\">\ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ud575\ubd84\uc5f4<\/a>\u00a0\ucc98\ub9ac\ud558\uace0 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uc218\uc900\uc744 \uac10\uc18c\uc2dc\ucf1c \uc190\uc0c1 \ubc1c\uc0dd \uc18d\ub3c4\ub97c \ub2a6\ucda5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib124\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib124\"><span class=\"anchor-text\">[124]<\/span><\/a>. \uc2e0\uccb4\uac00 \ub2e4\uc591\ud55c \ub0b4\uc778\uc131 \ubc0f \uc678\uc778\uc131 \uc190\uc0c1 \uc790\uadf9\uc744 \ubc1b\uc73c\uba74 \uc2e0\uccb4\uc758 \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\uc758 \uc870\uc808 \uacfc\uc815\uc774 \ubcc0\uacbd\ub429\ub2c8\ub2e4. Drp1\uc758 \ubd84\ube44 \uac10\uc18c, \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc190\uc0c1, \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uae30\ub2a5 \uc7a5\uc560, \uc138\ud3ec\uc0ac\uba78 \ubc0f \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uc99d\uac00\ub85c \ub098\ud0c0\ub098\uba70, \uc774\ub294 \uccb4\ub0b4\uc758 \ub2e4\uc591\ud55c \uc9c8\ubcd1\uc744 \uc720\ubc1c\ud569\ub2c8\ub2e4\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib125\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib125\"><span class=\"anchor-text\">[125]<\/span><\/a>. \ucd5c\uadfc \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uae30\ub2a5 \uc7a5\uc560\ub294 \ub1cc \ud5c8\ud608\/\uc7ac\uad00\ub958 \uc190\uc0c1 \ub3d9\uc548 NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4 \ud65c\uc131\ud654\ub97c \uc720\ub3c4\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib126\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib126\"><span class=\"anchor-text\">[126]<\/span><\/a>. \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub2e8\ubc31\uc9c8 2 \ubd84\ub9ac\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/uncoupling-protein-2\">\uacb0\ud569 \ud574\uc81c \ub2e8\ubc31\uc9c8 2<\/a>\u00a0(UCP2) \uacb0\ud54d\uc740 CIRI \ud6c4 \ub1cc \uc190\uc0c1\uc744 \uc545\ud654\uc2dc\ud0a4\uba70, \uc0c8\ub85c\uc6b4 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 UCP2 \uacb0\ud54d\uc740 \uc2dc\ud5d8\uad00 \ub0b4 \ubc0f \uc0dd\uccb4 \ub0b4\uc5d0\uc11c \uace0\ud608\ub2f9\uc99d \uc720\ubc1c CIRI \uc545\ud654 \ud6c4 NLRP3 \uc778\ud50c\ub77c\ub9c8\uc19c \ud65c\uc131\ud654\ub97c \ud5a5\uc0c1\uc2dc\ud0a4\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. UCP2\ub294 \uace0\ud608\ub2f9\uc73c\ub85c \uc778\ud55c CIRI \uc545\ud654\uc5d0 \ub300\ud55c \uc7a0\uc7ac\uc801\uc778 \uce58\ub8cc \ud45c\uc801\uc774 \ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. UCP2 \uacb0\ud54d\uc740 \ub610\ud55c \uc2dc\ud5d8\uad00 \ub0b4 \ubc0f \uc0dd\uccb4 \ub0b4 \ub274\ub7f0\uc5d0\uc11c NLRP3 \uc778\ud50c\ub77c\ub9c8\uc19c \ud65c\uc131\ud654 \ubc0f ROS \uc0dd\uc131\uc744 \ud5a5\uc0c1\uc2dc\ucf30\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib127\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib127\"><span class=\"anchor-text\">[127]<\/span><\/a>.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c Adiponectin\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/adiponectin\">\uc544\ub514\ud3ec\ub125\ud2f4<\/a>\u00a0\uad11\ubc94\uc704\ud55c \ud56d\uc0b0\ud654 \ubc0f \ud56d\uc5fc\uc99d \ud6a8\uacfc\ub97c \uc9c0\ub2cc \uc9c0\ubc29 \uc720\ub798 \ud638\ub974\ubaac\uc785\ub2c8\ub2e4. Adiponectin \ud3a9\ud0c0\uc774\ub4dc\ub294 AMPK\/GSK-3\u03b2\ub97c \uc870\uc808\ud558\uc5ec \ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1 \ud6c4 \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\uc640 NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4 \ud65c\uc131\ud654\ub97c \uc57d\ud654\uc2dc\ud0b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib128\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib128\"><span class=\"anchor-text\">[128]<\/span><\/a>. \ub530\ub77c\uc11c IS\uc5d0\uc11c\ub294 \ubc1c\uc5f4\uc99d\uc758 \ubc1c\uc0dd\uacfc \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc190\uc0c1 \uc0ac\uc774\uc5d0 \ubc00\uc811\ud55c \uad00\uacc4\uac00 \uc788\uc73c\uba70, \ub458 \uc0ac\uc774\uc5d0\ub294 \ubc00\uc811\ud55c \uc0c1\ud638 \uc791\uc6a9\uc774 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/section>\n<section id=\"sec0060\">\n<h3 id=\"sect0080\" class=\"u-h4 u-margin-m-top u-margin-xs-bottom\">2.7. \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\/\uc9c8\uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\ub294 IS \ud6c4 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \ub9e4\uac1c\ud569\ub2c8\ub2e4<\/h3>\n<p id=\"p0100\">\uc0b0\ud654\/\uc9c8\uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4 \ubc0f\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc2e0\uacbd\uc5fc\uc99d\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/neuroinflammation\">\uc2e0\uacbd\uc5fc\uc99d<\/a>\u00a0\ud575\uc2ec\uc774\ub2e4\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ubcd1\ub9ac\ud559\uc801 \uacfc\uc815\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/pathological-process\">\ubcd1\ub9ac\ud559\uc801 \uacfc\uc815<\/a>\u00a0\ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1, \uc911\uc7ac \uc2e0\uacbd \uc190\uc0c1, \ud608\uc561 \ub1cc \uc7a5\ubcbd \uc190\uc0c1 \ubc0f \ud5c8\ud608\uc131 \ub1cc\uc878\uc911 \uc911 \ucd9c\ud608 \ubcc0\ud615\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib129\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib129\"><span class=\"anchor-text\">[129]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib130\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib130\"><span class=\"anchor-text\">[130]<\/span><\/a>. \uc0b0\ud654\uc9c8\uc18c(NO) \ubc0f\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud37c\uc625\uc2dc\ub2c8\ud2b8\ub9ac\ud2b8\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/peroxynitrite\">\uacfc\uc0b0\ud654\uc9c8\uc0b0\uc5fc<\/a>\u00a0(ONOO-)\ub294 CIRI\uc758 \uc77c\ubc18\uc801\uc778 RNS\uc785\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib130\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib130\"><span class=\"anchor-text\">[130]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib131\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib131\"><span class=\"anchor-text\">[131]<\/span><\/a>. 3\uac1c\uc758 \uc774\uc131\uc9c8\uccb4\uac00 \uc788\ub2e4\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc0b0\ud654\uc9c8\uc18c \ud569\uc131\ud6a8\uc18c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/nitric-oxide-synthase\">\uc0b0\ud654\uc9c8\uc18c \ud569\uc131\ud6a8\uc18c<\/a>:\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub0b4\ud53c \uc0b0\ud654\uc9c8\uc18c \ud569\uc131\ud6a8\uc18c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/endothelial-nitric-oxide-synthase\">\ub0b4\ud53c \uc0b0\ud654\uc9c8\uc18c \ud569\uc131\ud6a8\uc18c<\/a>\u00a0(eNOS)\ub294 \ub0ae\uc740 NO \ub18d\ub3c4\ub97c \uc0dd\uc131\ud558\uace0 \uc0dd\ub9ac\ud559\uc801 \uae30\ub2a5\uc744 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. ~\ud558\ub294 \ub3d9\uc548\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub274\ub7f0 \uc0b0\ud654\uc9c8\uc18c \ud569\uc131\ud6a8\uc18c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/neuronal-nitric-oxide-synthase\">\ub274\ub7f0 \uc0b0\ud654\uc9c8\uc18c \ud569\uc131\ud6a8\uc18c<\/a>\u00a0(nNOS) \ubc0f\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc720\ub3c4\uc131 \uc0b0\ud654\uc9c8\uc18c \ud569\uc131\ud6a8\uc18c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/inducible-nitric-oxide-synthase\">\uc720\ub3c4\uc131 \uc0b0\ud654\uc9c8\uc18c \ud569\uc131\ud6a8\uc18c<\/a>\u00a0(iNOS)\ub294 \ub192\uc740 NO \ub18d\ub3c4\ub97c \uc0dd\uc131\ud558\uc5ec \uc5fc\uc99d\uc744 \uc720\ubc1c\ud558\uace0 \ud608\uc561\ub1cc\uc7a5\ubcbd \ud22c\uacfc\uc131\uc744 \uc99d\uac00\uc2dc\ud0b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib132\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib132\"><span class=\"anchor-text\">[132]<\/span><\/a>. ROS\/RNS\uc758 \uacfc\uc789\uc0dd\uc0b0\uc740 \uc2a4\ud2b8\ub808\uc2a4\uac00 \ub9ce\uc740 \ubbf8\uc138\ud658\uacbd\uc744 \uc0dd\uc131\ud558\uace0 \uc77c\ub828\uc758 \uc138\ud3ec \uc2e0\ud638\uc804\ub2ec \uacc4\ud1b5\uc73c\ub85c \uc774\uc5b4\uc838 \uc5fc\uc99d, \ud608\uc561\ub1cc\uc7a5\ubcbd\uc758 \uacfc\ud22c\uacfc\uc131,\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub1cc\ubd80\uc885\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/brain-edema\">\ub1cc\ubd80\uc885<\/a>\u00a0\uadf8\ub9ac\uace0 \uc2e0\uacbd \uc138\ud3ec \uc0ac\uba78\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib133\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib133\"><span class=\"anchor-text\">[133]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib134\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib134\"><span class=\"anchor-text\">[134]<\/span><\/a>. \ud37c\uc625\uc2dc\ub2c8\ud2b8\ub9ac\ud2b8 \ub9e4\uac1c\uccb4\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c DNA \uac00\ub2e5\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/dna-strand\">DNA \uac00\ub2e5<\/a>\u00a0\uc911\ub2e8\ud558\uace0 \ud65c\uc131\ud654\ud569\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub9ac\ubcf4\uc790\uc784\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/ribozyme\">\ub9ac\ubcf4\uc790\uc784<\/a>\u00a0\ud3f4\ub9ac(ADP-\ub9ac\ubcf4\uc2a4) \uc911\ud569\ud6a8\uc18c(PARP) \ub610\ub294 \ud3f4\ub9ac(ADPribose)\ub77c\uace0\ub3c4 \uc54c\ub824\uc9c4 \ud3f4\ub9ac(ADP-\ub9ac\ubcf4\uc2a4) \uc2e0\ud0c0\uc81c(PARS)\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc804\uc774\ud6a8\uc18c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/transferase\">\uc804\uc774\ud6a8\uc18c<\/a>\u00a0(pADPRT). ONOO- PARP\ub97c \uc9c1\uc811 \ud65c\uc131\ud654\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib135\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib135\"><span class=\"anchor-text\">[135]<\/span><\/a>, \uc0dd\uccb4 \ub0b4 \ubc0f \uc2dc\ud5d8\uad00 \ub0b4 \uc2e4\ud5d8\uc740 \ud5c8\ud608\uc131 \ub1cc \uc190\uc0c1\uc5d0\uc11c ONOO-\/PARP \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\uc758 \uc5ed\ud560\uc744 \uc785\uc99d\ud588\uc2b5\ub2c8\ub2e4. \uc0dd\uccb4 \ub0b4 \uc2e4\ud5d8\uc5d0\uc11c\ub294 NOS\uac00 \uacb0\ud54d\ub41c \uc950\uac00 \ud5c8\ud608\uc131 \ub1cc\uc878\uc911 \ub3d9\ubb3c \ubaa8\ub378\uc5d0\uc11c PARP \ud65c\uc131\ud654\uac00 \ub35c \ub098\ud0c0\ub098\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uc2dc\ud5d8\uad00 \ub0b4 \uc2e4\ud5d8\uc5d0\uc11c\ub294 NO \uae30\uc99d\uc790\uac00 \uc544\ub2cc ONOO \uae30\uc99d\uc790\uac00 \ubc30\uc591\ub41c C6\uc5d0\uc11c PARP \ud65c\uc131\ud654\ub97c \uc720\uc758\ud558\uac8c \uc720\ub3c4\ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc2e0\uacbd\uad50\uc885 \uc138\ud3ec\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/glioma-cell\">\uc2e0\uacbd\uad50\uc885 \uc138\ud3ec<\/a>.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc720\uc804\uc790 \ud30c\uad34\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/gene-disruption\">\uc720\uc804\uc790 \ud30c\uad34<\/a>\u00a0\ub610\ub294 PARP\uc758 \uce68\ubb35\uc774 \ud06c\uac8c \uac10\uc18c\ud569\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub1cc\uacbd\uc0c9 \ud06c\uae30\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/brain-infarction-size\">\ub1cc\uacbd\uc0c9 \ud06c\uae30<\/a>, \uc644\ud654\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc2e0\uacbd\ub3c5\uc131\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/neurotoxicity\">\uc2e0\uacbd\ub3c5\uc131<\/a>, \uc2e0\uacbd\ud608\uad00 \ub2e8\uc704\ub97c \ubcf4\ud638\ud558\uace0 \uc2e0\uacbd\ud559\uc801 \uacb0\uacfc\ub97c \uac1c\uc120\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib136\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib136\"><span class=\"anchor-text\">[136]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib137\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib137\"><span class=\"anchor-text\">[137]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib138\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib138\"><span class=\"anchor-text\">[138]<\/span><\/a>. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 ROS\/RNS\ub294 CIRI \ub3d9\uc548 \uc5fc\uc99d\ubcf5\ud569\uccb4\uc758 \ud65c\uc131\ud654 \uc778\uc790\uc77c \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib139\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib139\"><span class=\"anchor-text\">[139]<\/span><\/a>. \uc778\ud50c\ub77c\ub9c8\uc19c\uc740 \uc18c\uad50\uc138\ud3ec\uc9c8\uc758 \ub2e4\uc911 \ub2e8\ubc31\uc9c8 \ubcf5\ud569\uccb4\ub85c, \uadf8 \uc911 NOD \uc720\uc0ac \uc218\uc6a9\uccb4 3(NLRP3)\uc774 \uac00\uc7a5 \ub110\ub9ac \uc5f0\uad6c\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4. NLRP3\ub294 \uce74\uc2a4\ud30c\uc81c-1\uc744 \uc720\ubc1c \ubc0f \ud65c\uc131\ud654\ud558\uace0, IL-1\u03b2 \ubc0f IL-18\uc744 \ud65c\uc131\ud654\ud558\uc5ec \uc774\ub97c \ub1cc\ub85c \ubc29\ucd9c\ud569\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc138\ud3ec\uc678 \uacf5\uac04\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/extracellular-space\">\uc138\ud3ec\uc678 \uacf5\uac04<\/a>, \uc5fc\uc99d\uc758 \ubc1c\ub2ec\uc744 \ucd09\uc9c4\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib140\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib140\"><span class=\"anchor-text\">[140]<\/span><\/a>. \uc0dd\uccb4 \ub0b4 \uc2e4\ud5d8\uc5d0\uc11c\ub294 NLPR3 \ub179\uc544\uc6c3 \ub9c8\uc6b0\uc2a4\uc758 \ub1cc\uacbd\uc0c9 \ud06c\uae30\uc640 BBB \uc190\uc0c1\uc774 \uc57c\uc0dd\ud615 \ub9c8\uc6b0\uc2a4\uc758 \uacbd\uc6b0\ubcf4\ub2e4 \ub0ae\uc558\ub2e4. \ucd94\uac00 \uc2e4\ud5d8\uc5d0\uc11c\ub294 NLRP3\uac00 IL-1\u03b2\uc758 \ubc29\ucd9c\uc744 \uc911\uc7ac\ud558\uace0 \ub300\ub1cc \ubbf8\uc138\ud608\uad00 \ub0b4\ud53c \uc138\ud3ec\uc758 \ud22c\uacfc\uc131\uc744 \uc99d\uac00\uc2dc\ud0ac \uc218 \uc788\uc74c\uc744 \ubcf4\uc5ec\uc8fc\uc5c8\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib141\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib141\"><span class=\"anchor-text\">[141]<\/span><\/a>. \ud575 \uc778\uc790 E2 \uad00\ub828\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc694\uc18c 2\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/prothrombin\">\uc694\uc778 2<\/a>\u00a0(Nrf2)\ub294 \uc138\ud3ec \ud56d\uc0b0\ud654 \ubc18\uc751\uc744 \uc870\uc808\ud558\uace0 Nrf2\ub294 \uc0b0\uc18c \ubc0f \ud3ec\ub3c4\ub2f9 \uacb0\ud54d \uc0c1\ud0dc\uc5d0\uc11c BV2 \ubbf8\uc138\uc544\uad50\uc138\ud3ec\uc5d0\uc11c ROS \ub9e4\uac1c NLRP3 \uc0dd\uc131\uc744 \uc5b5\uc81c\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib142\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib142\"><span class=\"anchor-text\">[142]<\/span><\/a>. \uc0b0\ud654\/\uc9c8\uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\ub294 \uce74\uc2a4\ud30c\uc81c1\/\uc5fc\uc99d\ubcf5\ud569\uccb4 \ud65c\uc131\ud654\uc758 \uc8fc\uc694 \uc720\ubc1c \uc694\uc778\uc774 \ub420 \uc218 \uc788\ub294 \ud37c\uc625\uc2dc\ub2c8\ud2b8\ub77c\uc774\ud2b8\uc758 \ud615\uc131\uc744 \uc720\ub3c4\ud558\ub294 \uac83\uc73c\ub85c \ubc1d\ud600\uc84c\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib143\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib143\"><span class=\"anchor-text\">[143]<\/span><\/a>. \ub530\ub77c\uc11c ROS\/RNS \ub9e4\uac1c \uc5fc\uc99d\ubcf5\ud569\uccb4\ub294 \ud5c8\ud608\uc131 \ub1cc\uc190\uc0c1\uc5d0 \ub300\ud55c \uc7a0\uc7ac\uc801\uc778 \uce58\ub8cc \ud45c\uc801\uc774 \ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<p id=\"p0105\">\ub610\ud55c ROS\/RNS\ub294 Toll \uc720\uc0ac \uc218\uc6a9\uccb4\uc758 \ud65c\uc131\ud654\ub97c \uc911\uc7ac\ud569\ub2c8\ub2e4. \ud604\uc7ac \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 TLR(Toll-like Receptor)\uc740 \ud0c0\uace0\ub09c \uc218\uc6a9\uccb4\ub85c \ub110\ub9ac \uc5f0\uad6c\ub418\uc5b4 \uc654\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uba74\uc5ed \uc218\uc6a9\uccb4\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/immune-system-receptors\">\uba74\uc5ed \uc218\uc6a9\uccb4<\/a>\ubc0f TLR4\/2\ub294 \ub300\ub1cc\uc5d0\uc11c \ub354 \ub9ce\uc774 \uc5f0\uad6c\ub418\uc5c8\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud5c8\ud608\uc131 \uc190\uc0c1\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/ischemic-injury\">\ud5c8\ud608\uc131 \uc190\uc0c1<\/a>.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c TLR4\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/toll-like-receptor-4\">TLR4<\/a>\u00a0IL-1\u03b2, MMP-9, iNOS \ubc0f COX-2\uc758 \ubc1c\ud604\uc744 \uc911\uc7ac\ud558\uace0 \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\ub85c \uc778\ud55c \ub1cc \uc190\uc0c1\uc744 \uc545\ud654\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib144\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib144\"><span class=\"anchor-text\">[144]<\/span><\/a>. TLR4 \uc5b5\uc81c\uc81c\uc758 \uc801\uc6a9\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c E5564\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/eritoran\">E5564<\/a>\u00a0\uc7ac\uc0dd\ud560 \uc218 \uc788\uc74c\uc744 \ubcf4\uc5ec\uc8fc\uc5c8\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc2e0\uacbd\ubcf4\ud638\uc81c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/neuroprotective-agent\">\uc2e0\uacbd\ubcf4\ud638<\/a>\u00a0\uc18c\uad50\uc138\ud3ec\uc758 \ud65c\uc131\ud654\uc640 ROS \uc0dd\uc131\uc744 \uc5b5\uc81c\ud568\uc73c\ub85c\uc368 \uc5ed\ud560\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib145\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib145\"><span class=\"anchor-text\">[145]<\/span><\/a>. IS \ud6c4, TLR4 \uacb0\ud54d \ub9c8\uc6b0\uc2a4\uc758 \uacbd\uc0c9 \ud06c\uae30\ub294 \uc57c\uc0dd\ud615 \ub9c8\uc6b0\uc2a4\uc758 \uacbd\uc0c9 \ud06c\uae30\ubcf4\ub2e4 \ud604\uc800\ud788 \uc791\uc558\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib146\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib146\"><span class=\"anchor-text\">[146]<\/span><\/a>. TLR4\ub294 post-IS\uc5d0\ub3c4 \uad00\uc5ec\ud569\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc2e0\uacbd\ubc1c\uc0dd\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/neurogenesis\">\uc2e0\uacbd\ubc1c\uc0dd<\/a>.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc591\uc804\uc790 \ubc29\ucd9c \ub2e8\uce35 \ucd2c\uc601\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/positron-emission-tomography\">\uc591\uc804\uc790 \ubc29\ucd9c \ub2e8\uce35 \ucd2c\uc601<\/a>\u00a0\uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 TLR4 \uacb0\ud54d \ub9c8\uc6b0\uc2a4\ub294 IS\uc5d0\uc11c \uc2e0\uacbd \ubc1c\uc0dd\uc744 \uac15\ud654\ud558\uace0 \uc5fc\uc99d \ubc18\uc751\uc744 \uc5b5\uc81c\ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib147\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib147\"><span class=\"anchor-text\">[147]<\/span><\/a>. \ub610\ud55c, \uc0dd\uccb4 \ub0b4 \uc2e4\ud5d8 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 TLR2\/4\/NF-\u03baB \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub97c \uc5b5\uc81c\ud558\uba74 \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4, \uc5fc\uc99d \ubc18\uc751 \uc870\uc808 \ubc0f \ud5c8\ud608\uc131 \ub1cc \uc870\uc9c1 \ubcf4\ud638\uc5d0 \ud2b9\uc815 \ud6a8\uacfc\uac00 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib148\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib148\"><span class=\"anchor-text\">[148]<\/span><\/a>. \ub530\ub77c\uc11c TLR4\/2\ub294 \ud5c8\ud608\uc131 \ub1cc \uc190\uc0c1\uc758 \uce58\ub8cc \ud45c\uc801\uc774 \ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/section>\n<\/section>\n<section id=\"sec0065\">\n<h2 id=\"sect0085\" class=\"u-h4 u-margin-l-top u-margin-xs-bottom\">3. \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc640 IS\uc758 \uad00\uacc4<\/h2>\n<p id=\"p0110\">\ub300\ub1cc\uc758 \ubcd1\ub9ac\ud559 \uc801 \uba54\ucee4\ub2c8\uc998\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud5c8\ud608\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/ischemia\">\uad6d\uc18c \ube48\ud608<\/a>\u00a0\ud5c8\ud608 \ud6c4 \uc7ac\uad00\ub958 \uc190\uc0c1\uc740 \ubcf5\uc7a1\ud569\ub2c8\ub2e4. \uc774 \uacfc\uc815\uacfc \uad00\ub828\ub41c \uba54\ucee4\ub2c8\uc998\uc5d0\ub294 \uc5fc\uc99d, \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4, \uc790\uac00\ud3ec\uc2dd, \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uae30\ub2a5 \uc7a5\uc560, \uce7c\uc298 \uacfc\ubd80\ud558 \ubc0f \ud504\ub85c\uadf8\ub7a8\ud654\ub41c \uc138\ud3ec \uc0ac\uba78\uc774 \ud3ec\ud568\ub429\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib149\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib149\"><span class=\"anchor-text\">[149]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib150\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib150\"><span class=\"anchor-text\">[150]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib151\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib151\"><span class=\"anchor-text\">[151]<\/span><\/a>. \ub2e4\uc218\uc758 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \ud504\ub85c\uadf8\ub7a8\ud654\ub41c \uc138\ud3ec \uc0ac\uba78\uc740 \ub1cc \ud5c8\ud608 \ubc0f \ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc758 \ubcd1\ub9ac\ud559\uc801 \uacfc\uc815\uc5d0\uc11c \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud558\uba70, \uc704\uc758 \uba54\ucee4\ub2c8\uc998, \ud2b9\ud788 \ubc1c\uc5f4\uc99d\uacfc \uc5bd\ud600 \ubc00\uc811\ud558\uac8c \uad00\ub828\ub418\uc5b4 \uc788\uc74c\uc774 \ubc1d\ud600\uc84c\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib152\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib152\"><span class=\"anchor-text\">[152]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib153\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib153\"><span class=\"anchor-text\">[153]<\/span><\/a>. \ud504\ub85c\uadf8\ub7a8\ub41c \uc138\ud3ec \uc0ac\uba78\uc740 \ub274\ub7f0\uacfc \uad00\ub828\ub41c \ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc758 \uc8fc\uc694 \uc0ac\uac74\uc785\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc18c\uad50\uc138\ud3ec\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/microglia\">\uc18c\uad50\uc138\ud3ec<\/a>, \uc131\uc0c1 \uc138\ud3ec,\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud608\uad00 \ub0b4\ud53c \uc138\ud3ec\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/vascular-endothelial-cell\">\ud608\uad00 \ub0b4\ud53c \uc138\ud3ec<\/a>\ub4f1, \uc138\ud3ec\uc0ac\uba78\uacfc \uac19\uc740\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib154\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib154\"><span class=\"anchor-text\">[154]<\/span><\/a>, \uc790\uac00\ud3ec\uc2dd\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib155\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib155\"><span class=\"anchor-text\">[155]<\/span><\/a>, \ud504\ub85c\uadf8\ub7a8\ub41c \uad34\uc0ac \ub610\ub294 \uad34\uc0ac\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib156\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib156\"><span class=\"anchor-text\">[156]<\/span><\/a>,\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud398\ub86d\ud1a0\uc2dc\uc2a4\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/ferroptosis\">\ud398\ub86d\ud1a0\uc99d<\/a>\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib157\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib157\"><span class=\"anchor-text\">[157]<\/span><\/a>, \uadf8\ub9ac\uace0 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib158\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib158\"><span class=\"anchor-text\">[158]<\/span><\/a>. \ud2b9\ud788 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc5d0\uc11c\ub294 \ub1cc\ud5c8\ud608 \ub7ab\ud2b8 \ubaa8\ub378\uc5d0\uc11c NLRP1, ASC, Caspase-1, GSDMD \ub4f1 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uad00\ub828 \ub2e8\ubc31\uc9c8\uc758 \ubc1c\ud604\uc774 \uc99d\uac00\ud558\uba70, NLRP1\uc744 \uc5b5\uc81c\ud558\uba74 \uc5fc\uc99d\uacfc \ub1cc\uc758 \uc5fc\uc99d\uc744 \uc644\ud654\uc2dc\ud0ac \uc218 \uc788\ub2e4\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud5c8\ud608\uc131 \uc190\uc0c1\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/ischemic-injury\">\ud5c8\ud608\uc131 \uc190\uc0c1<\/a>. \ub610\ud55c, \ub9cc\uc131 \ub1cc\ud5c8\ud608\uc774 \ubc1c\uc0dd\ud558\uba74 \uc138\ud3ec\ub294 DAMP\uc640 \uac19\uc740 \uc2e0\ud638\ub97c \ubc29\ucd9c\ud558\uc5ec \uc5fc\uc99d \ubc18\uc751\uc744 \ucd09\uc9c4\ud569\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c PAMP\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/pathogen-associated-molecular-pattern\">PAMP<\/a>, \uc77c\ub828\uc758 \ubcf5\uc7a1\ud55c \ubd84\uc790 \ubc18\uc751\uc744 \uc720\ubc1c\ud569\ub2c8\ub2e4. \uc774\ub54c \uc18c\uad50\uc138\ud3ec, \uc131\uc0c1\uad50\uc138\ud3ec \ub4f1 \ub450\uac1c\ub0b4 \uc2e0\uacbd\uba74\uc5ed \uc5fc\uc99d\uc138\ud3ec\uac00 \uc99d\uc2dd, \ud65c\uc131\ud654\ub418\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub098\uba70, \uc774\ub294 \uc2e0\uacbd\ud608\uad00 \ub2e8\uc704\ub97c \ub354\uc6b1 \uc190\uc0c1\uc2dc\ud0a8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib159\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib159\"><span class=\"anchor-text\">[159]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib160\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib160\"><span class=\"anchor-text\">[160]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib161\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib161\"><span class=\"anchor-text\">[161]<\/span><\/a>.<\/p>\n<section id=\"sec0070\">\n<h3 id=\"sect0090\" class=\"u-h4 u-margin-m-top u-margin-xs-bottom\">3.1. \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc640 \ub274\ub7f0<\/h3>\n<p id=\"p0115\">IS \uc774\ud6c4\uc5d0\ub294 \ub2e8\uc2dc\uac04\uc5d0 \uc911\uc2ec \ud5c8\ud608 \ubd80\uc704\uc5d0 \uad34\uc0ac\uac00 \ubc1c\uc0dd\ud558\uace0, \uc8fd\uc740 \uc138\ud3ec\ub294 \ub2e4\uc74c\uacfc \uac19\uc740 \uc704\ud5d8 \uc2e0\ud638\ub97c \ubc29\ucd9c\ud569\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c HMGB1 \ub2e8\ubc31\uc9c8\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/high-mobility-group-b1-protein\">HMGB1 \ub2e8\ubc31\uc9c8<\/a>,\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc5f4\ucda9\uaca9 \ub2e8\ubc31\uc9c8\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/heat-shock-protein\">\uc5f4\ucda9\uaca9 \ub2e8\ubc31\uc9c8<\/a>,\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud37c\uc625\uc2dc\ub2e4\uc81c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/peroxidase\">\uacfc\uc0b0\ud654\ud6a8\uc18c<\/a>\u00a0\uac00\uc871 \ub2e8\ubc31\uc9c8 \ub4f1 \uc774\ub7ec\ud55c \uc704\ud5d8 \uc2e0\ud638 \ubd84\uc790\ub294\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud328\ud134 \uc778\uc2dd \uc218\uc6a9\uccb4\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/pattern-recognition-receptor\">\ud328\ud134 \uc778\uc2dd \uc218\uc6a9\uccb4<\/a>, \ud615\ud0dc\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc778\ud50c\ub77c\ub9c8\uc19c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/inflammasome\">\uc5fc\uc99d\ubcf5\ud569\uccb4<\/a>, \uc120\ucc9c\uc801 \uba74\uc5ed \ubc18\uc751\uc744 \uc2dc\uc791\ud558\uace0 \uc2e0\uacbd \uc138\ud3ec \uc0ac\uba78\uc744 \uc720\ubc1c\ud569\ub2c8\ub2e4\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib162\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib162\"><span class=\"anchor-text\">[162]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib163\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib163\"><span class=\"anchor-text\">[163]<\/span><\/a>. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \ub1cc\ud5c8\ud608\uc774 NLRP1\uc758 \ub192\uc740 \ubc1c\ud604\uc73c\ub85c \uc774\uc5b4\uc9c8 \uc218 \uc788\uc74c\uc774 \ud655\uc778\ub418\uc5c8\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c NLRP3\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/nucleotide-binding-oligomerization-domain-like-receptor\">NLRP3<\/a>\u00a0\ud5c8\ud608\uc131 \ub1cc \uc870\uc9c1\uacfc \ub274\ub7f0\uc5d0 \uc874\uc7ac\ud558\uba70, NLRP1\uc758 \ud65c\uc131\ud654\ub294 \uc8fc\ub85c \ub274\ub7f0\uc5d0 \uc874\uc7ac\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib164\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib164\"><span class=\"anchor-text\">[164]<\/span><\/a>. \uce74\uc2a4\ud30c\uc81c-1 \uc5b5\uc81c\uc81c \ub610\ub294 \uba74\uc5ed\uae00\ub85c\ubd88\ub9b0 \uc81c\uc81c\ub97c \uc0ac\uc6a9\ud558\uba74 \uc77c\ucc28 \ud53c\uc9c8 \ub274\ub7f0\uc5d0\uc11c NLRP1 \ubc0f NLRP3\uc758 \ubc1c\ud604\uc744 \uc57d\ud654\uc2dc\ud0a4\uace0 \ud06c\uae30\ub97c \uc904\uc77c \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub1cc\uacbd\uc0c9\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/brain-infarction\">\ub1cc\uacbd\uc0c9<\/a>, \uadf8 \uba54\ucee4\ub2c8\uc998\uc740 NF-\u03baB \ubc0f MAPK \uacbd\ub85c \ud65c\uc131\ud654\uc758 \uc5b5\uc81c\uc640 \uad00\ub828\uc774 \uc788\uc744 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib164\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib164\"><span class=\"anchor-text\">[164]<\/span><\/a>. IS \ub9c8\uc6b0\uc2a4\uc5d0\uc11c Li et al.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib165\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib165\"><span class=\"anchor-text\">[165]<\/span><\/a>\u00a0\ub1cc\ud5c8\ud608 \ubc1c\uc0dd 3\uc77c\uc9f8\uc5d0 \uc2e0\uacbd\ud50c\ub77c\uc988\ub9c8, \ud575 \ubc0f\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ub9c9\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/mitochondrial-membrane\">\ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ub9c9<\/a>\u00a0\ubc1c\uc0dd\ud558\uc600\uace0, Caspase-1, GSDMD \ubc0f IL-1\u03b2\uc758 \ubc1c\ud604\uc774 \uc720\uc758\ud558\uac8c \uc99d\uac00\ud558\uc600\ub2e4. \uce74\uc2a4\ud30c\uc81c-1 \uc5b5\uc81c\uc81c\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c Vx765\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/belnacasan\">Vx765<\/a>\u00a0\ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc5b5\uc81c\ud558\uace0, \ud5c8\ud608\uc131 \ubd80\uc704\uc758 \ub274\ub7f0 \uc0dd\uc874\uc744 \ucd09\uc9c4\ud558\uba70,\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub1cc \uae30\ub2a5 \uc7a5\uc560\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/brain-dysfunction\">\ub1cc \uae30\ub2a5 \uc7a5\uc560<\/a>\u00a0\uc950\uc5d0\uc11c. Lianget al.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib166\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib166\"><span class=\"anchor-text\">[166]<\/span><\/a>\u00a0\ub294 \uae34 \ube44\ucf54\ub529 RNA \ubaa8\uccb4 \ubc1c\ud604 \uc720\uc804\uc790 3(MEG3)\uc774 AIM2\/Caspase-1 \uacbd\ub85c\ub97c \ud65c\uc131\ud654\ud558\uc5ec \ubc1c\uc5f4\uc99d \ubc0f \uc5fc\uc99d \ubc18\uc751\uc744 \ucd09\uc9c4\ud558\uc5ec \ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc744 \uc77c\uc73c\ud0a8\ub2e4\ub294 \uc0ac\uc2e4\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4. MEG3 \uc720\uc804\uc790\uc758 \ub179\uc544\uc6c3\uc740 \ub2e4\uc74c\uc758 \ubc1c\ud604\uc744 \uc5b5\uc81c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c AIM2\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/nodular-melanoma\">AIM2<\/a>, Caspase-1, GSDMD \ubc0f \uae30\ud0c0 \ub2e8\ubc31\uc9c8\uc744 \ud568\uc720\ud558\uace0 \ud5c8\ud608\uc131 \ub1cc \uc190\uc0c1\uc744 \uc644\ud654\ud569\ub2c8\ub2e4. \uc774\ub294 MEG3\uac00 \ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc758 \ud6a8\uacfc\uc801\uc778 \uce58\ub8cc \ud45c\uc801\uc774 \ub420 \uc218 \uc788\uc74c\uc744 \uc2dc\uc0ac\ud569\ub2c8\ub2e4.<\/p>\n<\/section>\n<section id=\"sec0075\">\n<h3 id=\"sect0095\" class=\"u-h4 u-margin-m-top u-margin-xs-bottom\">3.2. \uc5f4\ubd84\ud574\uc99d\uacfc \uc131\uc0c1\uad50\uc138\ud3ec<\/h3>\n<p id=\"p0120\">\uc131\uc0c1 \uc138\ud3ec\uac00 \uac00\uc7a5 \ud48d\ubd80\ud569\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc2e0\uacbd\uad50\uc138\ud3ec\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/glial-cells\">\uc2e0\uacbd\uad50\uc138\ud3ec<\/a>\u00a0\uc5d0\uc11c\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc911\ucd94\uc2e0\uacbd\uacc4\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/central-nervous-system\">\uc911\ucd94 \uc2e0\uacbd\uacc4<\/a>\u00a0\ud608\uc561-\ub1cc \uc7a5\ubcbd \ud615\uc131, \uc2e0\uacbd \ub300\uc0ac \uc870\uc808 \ubc0f \uc138\ud3ec \uac04 \uc758\uc0ac\uc18c\ud1b5 \uc548\uc815\ud654\uc5d0 \uad00\uc5ec\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib167\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib167\"><span class=\"anchor-text\">[167]<\/span><\/a>. IS \uc774\ud6c4 \ub208\uc5d0 \ub744\ub294 \ubcd1\ub9ac\ud559\uc801 \ubcc0\ud654\ub294 \ubc18\uc751\uc801\uc785\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc131\uc0c1\uad50\uc99d\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/astrocytosis\">\uc131\uc0c1\uad50\uc99d<\/a>\u00a0\ud5c8\ud608\uc131 \uc190\uc0c1 \ud6c4 \ucd08\uae30\uc5d0 \uc2e0\uacbd \uac00\uc18c\uc131\uc744 \ucd09\uc9c4\ud558\ub294 \uc2e0\uacbd\uad50 \ud749\ud130\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib168\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib168\"><span class=\"anchor-text\">[168]<\/span><\/a>. \uc77c\ubc18\uc801\uc73c\ub85c \ub2e4\uc74c\uacfc \uac19\uc774 \ubbff\uc5b4\uc9d1\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud574\ub9c8\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/hippocampus\">\ud574\ub9c8<\/a>\u00a0\ud5c8\ud608\uc774\uace0\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc800\uc0b0\uc18c\uc99d\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/hypoxia\">\uc800\uc0b0\uc18c\uc99d<\/a>,\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud56d\uc0b0\ud654 \ub2a5\ub825\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/antioxidant-capacity\">\ud56d\uc0b0\ud654 \ub2a5\ub825<\/a>\u00a0\ud574\ub9c8\uc758 \uc57d\ud654\ub85c \uc778\ud574 \uc218\ub9ce\uc740 \uc5fc\uc99d\uc778\uc790\uac00 \ubc29\ucd9c\ub418\uc5b4 \ud574\ub9c8\uc758 \uc190\uc0c1\uc774 \uc545\ud654\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib169\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib169\"><span class=\"anchor-text\">[169]<\/span><\/a>. \uad6d\uc18c \ub1cc \ud5c8\ud608 \ud6c4 3\uc2dc\uac04\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c SD \uc950\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/sprague-dawley-rat\">SD \uc950<\/a>, IL-1\u03b2 \uc720\uc0ac \uba74\uc5ed \ubc18\uc751 \uc591\uc131 \uc138\ud3ec\ub294 \ud5c8\ud608\uc131 \ubd80\uc704, \uc8fc\ub85c \ubd88\ud65c\uc131 \uc131\uc0c1 \uc138\ud3ec\uc5d0 \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \ud5c8\ud608 \ud6c4 2\uac1c\uc6d4\uae4c\uc9c0 \ud5c8\ud608\uc131 \ubc18\uad6c, \ud2b9\ud788 \uad34\uc0ac \ubcd1\uc18c \uc8fc\ubcc0\uc5d0\uc11c \uc591\uc131 \uc138\ud3ec\uac00 \uc5ec\uc804\ud788 \uac80\ucd9c\ub420 \uc218 \uc788\uc73c\uba70 \ud65c\uc131\ud654 \uc815\ub3c4\uac00 \ub192\uc544\uc9d1\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib170\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib170\"><span class=\"anchor-text\">[170]<\/span><\/a>. \ud65c\uc131\ud654\ub41c \uc131\uc0c1\uad50\uc138\ud3ec\ub294 \ub2e4\uc74c\uc758 \ubc29\ucd9c\uc744 \uc720\ub3c4\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc885\uc591 \uad34\uc0ac \uc778\uc790\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/tumor-necrosis-factor\">\uc885\uc591\uad34\uc0ac\uc778\uc790<\/a>, \uc778\ud130\ub8e8\ud0a8, \uc131\uc7a5 \uc778\uc790 \ubc0f \uae30\ud0c0 \uc5fc\uc99d \uc778\uc790 \ub610\ub294 \uc2e0\uacbd \ub3c5\uc131 \ub9e4\uac1c\uccb4\ub85c \uc778\ud574 \uc2e0\uacbd \uc190\uc0c1\uc774 \ubc1c\uc0dd\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib171\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib171\"><span class=\"anchor-text\">[171]<\/span><\/a>. NLRP2\ub294 \uc8fc\ub85c \uc131\uc0c1\uad50\uc138\ud3ec\uc5d0\uc11c \ubc1c\ud604\ub418\uc9c0\ub9cc \ub274\ub7f0\uacfc \uc18c\uad50\uc138\ud3ec\uc5d0\uc11c\ub294 \uac70\uc758 \ubc1c\ud604\ub418\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \ub354\uc6b1\uc774, NLRP2\uc758 \ubc1c\ud604\uc740 \ub9c8\uc6b0\uc2a4 \ub300\ub1cc \ud5c8\ud608 \ubaa8\ub378\uc5d0\uc11c \uadf8\ub9ac\uace0 \uc131\uc0c1\uad50\uc138\ud3ec\uc5d0\uc11c \uc0b0\uc18c \ubc0f \ud3ec\ub3c4\ub2f9 \uacb0\ud54d \ud6c4\uc5d0 \uc0c1\ub2f9\ud788 \uc0c1\ud5a5\uc870\uc808\ub418\uc5c8\uc73c\uba70, NLRP2\ub97c \uc5b5\uc81c\ud558\uba74 \uc0b0\uc18c \ubc0f \ud3ec\ub3c4\ub2f9 \uacb0\ud54d\uc5d0 \uc758\ud574 \uc720\ubc1c\ub41c \ubc1c\uc5f4\uc99d\uc744 \uac10\uc18c\uc2dc\ud0ac \uc218 \uc788\uc5c8\uc2b5\ub2c8\ub2e4\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib172\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib172\"><span class=\"anchor-text\">[172]<\/span><\/a>. \ub610 \ub2e4\ub978 \uc5f0\uad6c\uc5d0\uc11c\ub294 \ub1cc \ud5c8\ud608\uc758 \uc2dc\ud5d8\uad00 \ub0b4 \ubaa8\ub378\uc5d0\uc11c \uc0b0\uc18c-\ud3ec\ub3c4\ub2f9 \uacb0\ud54d\uc774 NLRP3, ASC, Caspase-1, IL-1\u03b2 \ubc0f IL-18\uc758 \uc99d\uac00\uc640 \uc131\uc0c1\uad50\uc138\ud3ec \uc0dd\uc874\uc758 \uac10\uc18c\ub85c \uc774\uc5b4\uc9c4\ub2e4\ub294 \uc0ac\uc2e4\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud788\ud53c\ub458\ub9b0\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/hispidulin\">\ud788\ud53c\ub458\ub9b0<\/a>\u00a0\uc5d0\uc11c \ubd84\ub9ac\ub41c \ucf00\ud1a4 \ud654\ud569\ubb3c\uc774\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud55c\uc57d\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/chinese-herbal-medicine\">\ud55c\uc57d<\/a>. \uc2dc\ud5d8\uad00 \ub0b4 \ubc0f \uc0dd\uccb4 \ub0b4 \uc2e4\ud5d8\uc5d0\uc11c \ud788\ud53c\ub458\ub9b0\uc740 NLRP3 \ub9e4\uac1c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc5b5\uc81c\ud558\uace0 \ub1cc\uc5d0 \ubcf4\ud638 \ud6a8\uacfc\ub97c \ubc1c\ud718\ud560 \uc218 \uc788\uc73c\uba70, \uadf8 \uba54\ucee4\ub2c8\uc998\uc740 AMPK\/GSK-3\u03b2\uc758 \ud65c\uc131\ud654\uc640 \uad00\ub828\uc774 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/signal-transduction\">\uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c<\/a>\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib173\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib173\"><span class=\"anchor-text\">[173]<\/span><\/a>. Menget al.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib174\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib174\"><span class=\"anchor-text\">[174]<\/span><\/a>\u00a0NLRP6\uc758 \ubc1c\ud604\uc740 \uc950\uc758 \ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958 \ud6c4 48\uc2dc\uac04\uc5d0 \ucd5c\uace0\uc870\uc5d0 \ub3c4\ub2ec\ud55c\ub2e4\ub294 \uac83\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4. \uc131\uc0c1\uad50\uc138\ud3ec\uc5d0\uc11c \uc0b0\uc18c \ubc0f \ud3ec\ub3c4\ub2f9 \uacb0\ud54d \ud6c4 NLRP6 \ubc0f \uadf8 \ud65c\uc131\ud654 \uc0dd\uc131\ubb3c\uc758 \uc0dd\uc131\uc774 \uc99d\uac00\ud558\uace0 NLRP6\ub97c \uc5b5\uc81c\ud558\uba74 ASC \ubc0f Caspase-1\uc774 \uac10\uc18c\ud558\uace0 \uc5fc\uc99d \uc778\uc790\uc758 \ubc29\ucd9c\uc774 \uac10\uc18c\ud558\uba70 \uc2e0\uacbd \ud65c\ub3d9\uc774 \uc99d\uac00\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib175\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib175\"><span class=\"anchor-text\">[175]<\/span><\/a>. \ub530\ub77c\uc11c \uc131\uc0c1\uad50\uc138\ud3ec\uc758 \uc5fc\uc99d\ubcf5\ud569\uccb4 \ud65c\uc131\ud654\ub97c \ubaa9\ud45c\ub85c \ud558\ub294 \uac1c\uc785\uc740 IS \uce58\ub8cc\uc5d0 \ub300\ud55c \uc0c8\ub85c\uc6b4 \uc544\uc774\ub514\uc5b4\ub97c \uc81c\uacf5\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/section>\n<section id=\"sec0080\">\n<h3 id=\"sect0100\" class=\"u-h4 u-margin-m-top u-margin-xs-bottom\">3.3. \uc5f4\ubd84\ud574\uc99d\uacfc \uc18c\uad50\uc138\ud3ec<\/h3>\n<p id=\"p0125\">\uc18c\uad50\uc138\ud3ec\ub294 \ud0c0\uace0\ub09c \uac83\uc785\ub2c8\ub2e4\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uba74\uc5ed \uc138\ud3ec\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/immunocompetent-cell\">\uba74\uc5ed\uc138\ud3ec<\/a>\u00a0\uc911\ucd94\uc2e0\uacbd\uacc4\uc640 \ud5c8\ud608\uc131 \ub1cc\uc878\uc911 \ud6c4 \uac00\uc7a5 \uba3c\uc800 \ud65c\uc131\ud654\ub418\ub294 \uc138\ud3ec\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib176\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib176\"><span class=\"anchor-text\">[176]<\/span><\/a>. \ub1cc\ud5c8\ud608 \uc190\uc0c1\uc758 \uae09\uc131\uae30\uc5d0\ub294 \uc18c\uad50\uc138\ud3ec\uac00 \ubcd1\ubcc0 \ubd80\uc704\ub85c \ube60\ub974\uac8c \uc774\ub3d9\ud558\uc5ec \uc5fc\uc99d\uc778\uc790 \ubc0f \uc138\ud3ec\ub3c5\uc131 \ubb3c\uc9c8\uc744 \ubd84\ube44\ud558\uc5ec \uc870\uc9c1 \uc190\uc0c1\uc744 \uc545\ud654\uc2dc\ud0a8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib177\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib177\"><span class=\"anchor-text\">[177]<\/span><\/a>. \ub9cc\uc131 \ub2e8\uacc4\uc5d0\uc11c \uc18c\uad50\uc138\ud3ec\ub294 \ud56d\uc5fc\uc99d\uc131 \uc0ac\uc774\ud1a0\uce74\uc778\uacfc \uc131\uc7a5 \uc778\uc790\ub97c \uc0dd\uc131\ud558\uc5ec\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc870\uc9c1 \ubcf5\uad6c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc2ed\uc2dc\uc624.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/tissue-repair\">\uc870\uc9c1 \ubcf5\uad6c<\/a>\u00a0\uadf8\ub9ac\uace0 \ub9ac\ubaa8\ub378\ub9c1\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib178\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib178\"><span class=\"anchor-text\">[178]<\/span><\/a>. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \uc18c\uad50\uc138\ud3ec \ubc1c\uc5f4\uc99d\uc740 \ud5c8\ud608\uc131 \ub1cc \uc190\uc0c1\uc5d0\uc11c \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. NLRC4\ub294 \uc18c\uad50\uc138\ud3ec\uc5d0 3\uc2dc\uac04 \ub3d9\uc548 \uc0b0\uc18c\uc640 \ud3ec\ub3c4\ub2f9\uc774 \ucc28\ub2e8\ub418\uc5c8\uc744 \ub54c \uc720\uc758\ud558\uac8c \uc99d\uac00\ud55c \ucd5c\ucd08\uc758 \uc778\ud50c\ub77c\ub9c8\uc19c\uc778 \ubc18\uba74, NLRP1, NLRP3 \ubc0f AIM2\ub294 \uc0b0\uc18c \ud3ec\ub3c4\ub2f9\uc774 \ubc15\ud0c8\ub41c 6\uc2dc\uac04 \uc774\ud6c4\uae4c\uc9c0 \uc720\uc758\ud558\uac8c \uc99d\uac00\ud558\uc9c0 \uc54a\uc558\uc2b5\ub2c8\ub2e4. NLRC4\ub97c \uc5b5\uc81c\ud558\uba74 GSDMD, IL-1\u03b2 \ubc0f IL-18\uc758 \uc0dd\uc131\uc744 \uac10\uc18c\uc2dc\ud0a4\uace0 \uc18c\uad50\uc138\ud3ec \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc5b5\uc81c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib179\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib179\"><span class=\"anchor-text\">[179]<\/span><\/a>. Xu et al.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib180\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib180\"><span class=\"anchor-text\">[180]<\/span><\/a>\u00a0\ub4dc\ub77c\uc774\ubc84 \uc218\uc6a9\uccb4 1(TREM-1)\uc774 \ub2e4\uc74c\uacfc \uac19\uc774 \ud45c\ud604\ub41c\ub2e4\uace0 \ubcf4\uace0\ud588\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uace8\uc218 \uc138\ud3ec\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/myeloid-cell\">\uace8\uc218 \uc138\ud3ec<\/a>\u00a0\ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958 \ud6c4 \ubbf8\uc138\uc544\uad50\uc138\ud3ec\uc5d0\uc11c NLRP3\/Caspase-1 \ub9e4\uac1c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uacbd\ub85c\ub97c \ud65c\uc131\ud654\ud558\uace0 \uc2e0\uacbd\uc5fc\uc99d \ubc18\uc751\uc744 \uc720\ub3c4\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. TREM-1\uc758 \uc5b5\uc81c\ub294 \uc18c\uad50\uc138\ud3ec \ubc1c\uc5f4\uc99d \ubc0f \uc2e0\uacbd \uc190\uc0c1\uc744 \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4. Li et al.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib181\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib181\"><span class=\"anchor-text\">[181]<\/span><\/a>\u00a0\ub294 \ub1cc \ud5c8\ud608 \ud6c4 \uc21c\ud658 \uad6c\uc544\ub178\uc2e0 \ubaa8\ub178\ud3ec\uc2a4\ud398\uc774\ud2b8-\uc544\ub370\ub178\uc2e0 \ud569\uc131 \ud6a8\uc18c(cGAS)\uc758 \ubc1c\ud604\uc774 \uc0c1\ud5a5 \uc870\uc808\ub418\uace0 AIM2 \uc5fc\uc99d\ubcf5\ud569\uccb4\ub97c \ud65c\uc131\ud654\ud558\uc5ec \uc18c\uad50\uc138\ud3ec \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc720\ub3c4\ud55c\ub2e4\ub294 \uac83\uc744 \ud655\uc778\ud588\uc2b5\ub2c8\ub2e4. cGAS \uae38\ud56d\uc81c A151\uc740 AIM2 \ud65c\uc131\ud654 \ubc0f \uc18c\uad50\uc138\ud3ec \ubc1c\uc5f4\uc99d\uc744 \uc5b5\uc81c\ud558\uace0 \ub1cc\uacbd\uc0c9\ub7c9\uc744 \ud06c\uac8c \uac10\uc18c\uc2dc\ud0a4\uba70 \uc2e0\uacbd \uc190\uc0c1\uc744 \uc644\ud654\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc704\uc758 \uc5f0\uad6c\ub294 \uc18c\uad50\uc138\ud3ec \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4(microglia pyroptosis)\uc640 \uadf8 \ub9e4\uac1c \uc2e0\uacbd\uc5fc\uc99d \ubc18\uc751\uc774 \ud5c8\ud608\uc131 \ub1cc \uc190\uc0c1\uc744 \ucd08\ub798\ud558\ub294 \uc911\uc694\ud55c \uba54\ucee4\ub2c8\uc998\uc77c \uc218 \uc788\uc74c\uc744 \ub098\ud0c0\ub0c5\ub2c8\ub2e4. \ubbf8\uc138\uc544\uad50\uc138\ud3ec\uc758 \uc2e0\uacbd\ub3c5\uc131 \ud6a8\uacfc\ub97c \uc5b5\uc81c\ud558\ub294 \uac83\uc740 \ud5c8\ud608\uc131 \ub1cc\uc878\uc911 \uce58\ub8cc\ub97c \uc704\ud55c \uc0c8\ub85c\uc6b4 \uc804\ub7b5\uc774 \ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/section>\n<section id=\"sec0085\">\n<h3 id=\"sect0105\" class=\"u-h4 u-margin-m-top u-margin-xs-bottom\">3.4. \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \ubc0f \ub0b4\ud53c \uc138\ud3ec<\/h3>\n<p id=\"p0130\">\ub0b4\ud53c \uc138\ud3ec\ub294 \ud608\uc561 \ub1cc \uc7a5\ubcbd\uc758 \uccab \ubc88\uc9f8 \uc7a5\ubcbd\uc744 \uad6c\uc131\ud558\uc5ec \ub2e4\uc74c\uc744 \uc704\ud55c \uc9c0\uc9c0\uccb4\ub97c \uc81c\uacf5\ud569\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c claudin\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/claudin\">\ud074\ub77c\uc6b0\ub518<\/a>,\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc811\ucc29 \ubd84\uc790\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/cell-adhesion-molecule\">\uc811\ucc29 \ubd84\uc790<\/a>\u00a0\uadf8\ub9ac\uace0\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc138\ud3ec\uc678 \uae30\uc9c8\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/extracellular-matrix\">\uc138\ud3ec\uc678 \uae30\uc9c8<\/a>\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib182\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib182\"><span class=\"anchor-text\">[182]<\/span><\/a>. \ub1cc\ud5c8\ud608 \uc911\uc5d0\ub294 \uba74\uc5ed \uc5fc\uc99d \ubc18\uc751\uacfc \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\uac00 \uc190\uc0c1\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub0b4\ud53c \uc138\ud3ec\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/endothelial-cell\">\ub0b4\ud53c \uc138\ud3ec<\/a>\u00a0\ud608\uc561\ub1cc\uc7a5\ubcbd\uc758 \uc644\uc804\uc131\uc744 \ud30c\uad34\ud558\uc5ec \ud608\uad00\uc131 \ubd80\uc885, \ucd9c\ud608\uc131 \ubcc0\ud615 \ubc0f \uc0ac\ub9dd\ub960 \uc99d\uac00\ub97c \ucd08\ub798\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib183\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib183\"><span class=\"anchor-text\">[183]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib184\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib184\"><span class=\"anchor-text\">[184]<\/span><\/a>. \ub1cc \ud5c8\ud608 \ud6c4 NLRP3\ub294 \ub274\ub7f0, \uc18c\uad50\uc138\ud3ec \ubc0f \ud608\uad00 \ub0b4\ud53c \uc138\ud3ec\uc5d0\uc11c \uc0c1\ud5a5 \uc870\uc808\ub418\uba70, NLRP3 \uc720\uc804\uc790\ub97c \uc5b5\uc81c\ud558\uba74 \ub2e4\uc74c\uacfc \uac19\uc740 \uc0dd\uc950\uc758 \ub1cc\uacbd\uc0c9 \uaddc\ubaa8\ub97c \uc904\uc77c \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc911\ub300\ub1cc\ub3d9\ub9e5\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/middle-cerebral-artery\">\uc911\ub1cc\ub3d9\ub9e5<\/a>\u00a0\ud5c8\ud608 \ubc0f \ud608\uc561 \ub1cc \uc7a5\ubcbd\uc758 \ud22c\uacfc\uc131\uc744 \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib185\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib185\"><span class=\"anchor-text\">[185]<\/span><\/a>. \uc655 \uc678.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib186\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib186\"><span class=\"anchor-text\">[186]<\/span><\/a>\u00a0\ub300\ub1cc \ud5c8\ud608\uc774 \ubbf8\uc138\ud608\uad00 \ub0b4\ud53c \uc138\ud3ec\uc758 \ubc1c\uc5f4\uc99d\uc744 \uc720\ubc1c\ud558\uace0 \ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc744 \uc545\ud654\uc2dc\ud0ac \uc218 \uc788\uc74c\uc744 \ud655\uc778\ud588\uc2b5\ub2c8\ub2e4. \uadf8\ub4e4\uc740 \ub610\ud55c \ud37c\uc625\uc2dc\uc880 \uc99d\uc2dd\uc778\uc790 \ud65c\uc131\ud654 \uc218\uc6a9\uccb4 \uac10\ub9c8 \ubcf4\uc870\ud65c\uc131\uc778\uc790 1\u03b1(PGC-1\u03b1)\uc758 \ud65c\uc131\ud654\uac00 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uad00\ub828 \ub2e8\ubc31\uc9c8\uc758 \ubc1c\ud604\uc744 \ud06c\uac8c \uac10\uc18c\uc2dc\ud0a4\uace0 ZO-1 \ubc0f ZO-1\uc758 \ubc1c\ud604\uc744 \uc99d\uac00\uc2dc\ud0a4\ub294 \uac83\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c Occludin\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/occludin\">\uc624\ud074\ub8e8\ub518<\/a>\u00a0\ub1cc \ubbf8\uc138 \ud608\uad00 \ub0b4\ud53c \uc138\ud3ec\uc758 \ub2e8\ubc31\uc9c8\uc744 \uc0ac\uc6a9\ud558\uc5ec \ud608\uc561 \ub1cc \uc7a5\ubcbd\uc758 \uc644\uc804\uc131\uc744 \ubcf4\ud638\ud569\ub2c8\ub2e4. \ub610\ud55c, \ub1cc \ubbf8\uc138\ud608\uad00 \ub0b4\ud53c\uc138\ud3ec\uc758 \uc5f4\ubd84\ud574\uc99d\uc740 IS \ud6c4 \ucd9c\ud608 \uac00\ub2a5\uc131\uc744 \uc99d\uac00\uc2dc\ucf1c \ub2e4\uc74c\uacfc \uac19\uc740 \uc2ec\uac01\ud55c \ud569\ubcd1\uc99d\uc744 \uc720\ubc1c\ud560 \uc218 \uc788\ub2e4\ub294 \uc5f0\uad6c \uacb0\uacfc\ub3c4 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub1cc\ucd9c\ud608\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/cerebral-hemorrhage\">\ub1cc\ucd9c\ud608<\/a>\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib187\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib187\"><span class=\"anchor-text\">[187]<\/span><\/a>.<\/p>\n<div>\n<p id=\"p0135\">\ub1cc\ud5c8\ud608\uacfc \ubc1c\uc5f4\uc99d \uc0ac\uc774\uc758 \uc5f0\uad00\uc131\uc740 \ub2e4\uc74c\uacfc \uac19\uc774 \uc694\uc57d\ub429\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#fig0010\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"fig0010\"><span class=\"anchor-text\">\uadf8\ub9bc 2<\/span><\/a>.<\/p>\n<figure id=\"fig0010\" class=\"figure text-xs\"><img decoding=\"async\" src=\"https:\/\/ars.els-cdn.com\/content\/image\/1-s2.0-S0753332222013889-gr2.jpg\" alt=\"Fig. 2\" height=\"362\" aria-describedby=\"cap0010\" \/><\/p>\n<ol class=\"u-margin-s-bottom\">\n<li><a class=\"anchor download-link u-font-sans u-display-inline anchor-default\" title=\"\uace0\ud574\uc0c1\ub3c4 \uc774\ubbf8\uc9c0 \ub2e4\uc6b4\ub85c\ub4dc(274KB)\" href=\"https:\/\/ars.els-cdn.com\/content\/image\/1-s2.0-S0753332222013889-gr2_lrg.jpg\" target=\"_blank\" rel=\"noopener\" download=\"\"><span class=\"anchor-text\">\ub2e4\uc6b4\ub85c\ub4dc :\u00a0<span class=\"download-link-title\">\uace0\ud574\uc0c1\ub3c4 \uc774\ubbf8\uc9c0 \ub2e4\uc6b4\ub85c\ub4dc(274KB)<\/span><\/span><\/a><\/li>\n<li><a class=\"anchor download-link u-font-sans u-display-inline anchor-default\" title=\"\uc804\uccb4 \ud06c\uae30 \uc774\ubbf8\uc9c0 \ub2e4\uc6b4\ub85c\ub4dc\" href=\"https:\/\/ars.els-cdn.com\/content\/image\/1-s2.0-S0753332222013889-gr2.jpg\" target=\"_blank\" rel=\"noopener\" download=\"\"><span class=\"anchor-text\">\ub2e4\uc6b4\ub85c\ub4dc :\u00a0<span class=\"download-link-title\">\uc804\uccb4 \ud06c\uae30 \uc774\ubbf8\uc9c0 \ub2e4\uc6b4\ub85c\ub4dc<\/span><\/span><\/a><\/li>\n<\/ol>\n<p id=\"sp0010\"><span class=\"label\">\uadf8\ub9bc 2<\/span>. IS \ud6c4 \ud608\uad00 \uc2e0\uacbd \ub2e8\uc704\uc758 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uba54\ucee4\ub2c8\uc998 \uc694\uc57d [\ud608\uad00 \uc2e0\uacbd \ub2e8\uc704(\uc18c\uad50\uc138\ud3ec, \uc131\uc0c1\uad50\uc138\ud3ec, \ub274\ub7f0\uc73c\ub85c \uad6c\uc131\ub428)\uc5d0 \ub300\ud55c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc758 \ubd84\uc790 \uba54\ucee4\ub2c8\uc998,\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud608\uad00 \ub0b4\ud53c \uc138\ud3ec\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/vascular-endothelial-cell\">\ud608\uad00 \ub0b4\ud53c \uc138\ud3ec<\/a>, pericytes) IS \uc774\ud6c4. IRF:\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc778\ud130\ud398\ub860 \uc870\uc808 \uc778\uc790\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/interferon-regulatory-factor\">\uc778\ud130\ud398\ub860 \uc870\uc808 \uc778\uc790<\/a>; IFN:\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc778\ud130\ud398\ub860\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/interferon\">\uc778\ud130\ud398\ub860<\/a>; CASP: \uce74\uc2a4\ud30c\uc81c; GPX4: \uae00\ub8e8\ud0c0\ud2f0\uc628 \ud37c\uc625\uc2dc\ub2e4\uc81c 4].<\/p>\n<\/figure>\n<\/div>\n<\/section>\n<\/section>\n<section id=\"sec0090\">\n<h2 id=\"sect0110\" class=\"u-h4 u-margin-l-top u-margin-xs-bottom\">4. IS \uce58\ub8cc\ub97c \uc704\ud55c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uc5b5\uc81c\uc81c\uc758 \uac00\ub2a5\uc131<\/h2>\n<p id=\"p0140\">\ucd5c\uadfc \uba87 \ub144 \ub3d9\uc548 IS\uc758 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uc5b5\uc81c\uc81c\uc5d0 \ub300\ud55c \uc5f0\uad6c\uac00 \ub9ce\uc740 \uc8fc\ubaa9\uc744 \ubc1b\uc558\uc2b5\ub2c8\ub2e4. Lianget al.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib188\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib188\"><span class=\"anchor-text\">[188]<\/span><\/a>\u00a0Caspase-1 \uc5b5\uc81c\uc81c VX-765\uac00 Caspase-1, ASC, GSDMD \ubc0f IL-1\u03b2\ub97c \uac10\uc18c\uc2dc\ud0a4\uba74\uc11c \uc218\uc900\uc744 \uc0c1\ud5a5 \uc870\uc808\ud560 \uc218 \uc788\uc74c\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ubc00\ucc29 \ub2e8\ubc31\uc9c8\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/tight-junction-protein\">\ubc00\ucc29\uc811\ud569 \ub2e8\ubc31\uc9c8<\/a>\u00a0\uadf8\ub9ac\uace0\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uae08\uc18d\ub2e8\ubc31\ubd84\ud574\ud6a8\uc18c\uc758 \uc870\uc9c1 \uc5b5\uc81c\uc81c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/metalloprotease-inhibitor\">\uba54\ud0c8\ub85c\ud504\ub85c\ud14c\uc774\ub098\uc81c\uc758 \uc870\uc9c1 \uc5b5\uc81c\uc81c<\/a>, \ud608\uc561 \ub1cc \uc7a5\ubcbd\uc758 \ubb34\uacb0\uc131\uc744 \ubcf4\ud638\ud569\ub2c8\ub2e4. \ub610\ud55c, VX-765\ub294 \uc18c\uad50\uc138\ud3ec\uc758 M1\ud615\uc5d0\uc11c M2\ud615\uc73c\ub85c\uc758 \uc804\ud658\uc744 \ucd09\uc9c4\ud558\uace0, \uc18c\uad50\uc138\ud3ec\uc5d0 \uc758\ud55c \uc5fc\uc99d\ubc18\uc751\uc744 \uac10\uc18c\uc2dc\ud0a4\uba70, \uc2e0\uacbd\ubcf4\ud638 \ud6a8\uacfc\ub97c \ubc1c\ud718\ud55c\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib189\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib189\"><span class=\"anchor-text\">[189]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib190\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib190\"><span class=\"anchor-text\">[190]<\/span><\/a>. MCC950\uc740 \uc120\ud0dd\uc801 NLRP3 \uc5b5\uc81c\uc81c\uc774\ub2e4. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 MCC950\uc740 \ud5c8\ud608\uc131 \ubc18\uadf8\ub9bc\uc790\uc5d0\uc11c NLRP3, Caspase-1 \ubc0f IL-1\u03b2\uc758 \ubc1c\ud604\uc744 \uac10\uc18c\uc2dc\ud0ac \uc218 \uc788\uc73c\uba70 \uc0dd\uc950\uc758 \uad6d\uc18c \ub1cc \ud5c8\ud608\uc5d0 \ubcf4\ud638 \ud6a8\uacfc\uac00 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib191\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib191\"><span class=\"anchor-text\">[191]<\/span><\/a>. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \uc77c\ubd80\ub294\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c microRNA\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/microrna\">\ub9c8\uc774\ud06c\ub85cRNA<\/a>\u00a0\ub1cc\ud5c8\ud608 \ubaa8\ub378\uc5d0\uc11c \ubc1c\uc5f4\uc99d\uc744 \uc5b5\uc81c\ud558\uace0 \uc2e0\uacbd\ubcf4\ud638 \uc5ed\ud560\uc744 \ud560 \uc218 \uc788\uc74c\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib192\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib192\"><span class=\"anchor-text\">[192]<\/span><\/a>. LP17\uc740 \uc5b5\uc81c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uace8\uc218 \uc138\ud3ec\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/myeloid-cell\">\uace8\uc218\uc138\ud3ec<\/a>\u00a0\uc218\uc6a9\uccb4-1\uc744 \uc720\ubc1c\ud558\uc5ec \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\uc640 \ubc1c\uc5f4\uc99d\uc744 \uc5b5\uc81c\ud558\uace0 \ub1cc \ud5c8\ud608\ub85c \uc778\ud55c \uc2e0\uacbd \uc190\uc0c1\uc744 \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib192\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib192\"><span class=\"anchor-text\">[192]<\/span><\/a>.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud788\uc2a4\ud2f0\ub518\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/histidine\">\ud788\uc2a4\ud2f0\ub518<\/a>\u00a0\uc544\ub370\ub2d0\ub808\uc774\ud2b8 \ud65c\uc131\ud654 \ub2e8\ubc31\uc9c8 \ud0a4\ub098\uc81c\/\uae00\ub9ac\ucf54\uac90 \ud569\uc131\ud6a8\uc18c \ud0a4\ub098\uc81c-3\u03b2 \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub97c \uc870\uc808\ud558\uc5ec NLRP3 \ub9e4\uac1c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc5b5\uc81c\ud558\uc5ec \ud56d-CIRI \uc2e0\uacbd \ubcf4\ud638 \ud6a8\uacfc\ub97c \ubc1c\ud718\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib193\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib193\"><span class=\"anchor-text\">[193]<\/span><\/a>. \uc800\ubc00\ub3c4 \uc9c0\ub2e8\ubc31\uc9c8 \uc218\uc6a9\uccb4\ub294 CIRI \ud6c4 NLRP3 \ub9e4\uac1c \uc2e0\uacbd \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc5b5\uc81c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib194\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib194\"><span class=\"anchor-text\">[194]<\/span><\/a>. \uc9c0\uc9c8 \uc54c\ucf54\uc62c \ub9e4\uac1c peroxisome proliferator \ud65c\uc131\ud654 \uc218\uc6a9\uccb4 \u03b1-\uae00\ub8e8\ud0c0\uba54\uc774\ud2b8 \uc625\uc0b4\ub85c\uc544\uc138\ud14c\uc774\ud2b8 \ud2b8\ub79c\uc2a4\uc544\ubbf8\ub098\uc81c 1 \ucd95\uc740 IS \ud6c4 \ub0b4\ud53c \uc138\ud3ec\uc758 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc5b5\uc81c\ud558\uace0 \ud5c8\ud608\uc131 \ub1cc \uc190\uc0c1\uc744 \uac1c\uc120\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib195\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib195\"><span class=\"anchor-text\">[195]<\/span><\/a>. CHRFAM7A\uc758 \uacfc\ubc1c\ud604\uc740 NLRP3\/\uce74\uc2a4\ud30c\uc81c-1 \uacbd\ub85c \uc758\uc874\uc131 \uc18c\uad50\uc138\ud3ec \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc5b5\uc81c\ud558\uace0 CIRI\ub97c \uc57d\ud654\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib196\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib196\"><span class=\"anchor-text\">[196]<\/span><\/a>. TP53 \uc720\ubc1c \ud574\ub2f9\uc791\uc6a9 \ubc0f \uc138\ud3ec\uc0ac\uba78 \uc870\uc808\uc81c\ub294 \ub300\ub1cc \ud5c8\ud608 \uc720\ubc1c \uc18c\uad50\uc138\ud3ec \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \ubc0f \ud5c8\ud608\uc131 \ub1cc \uc190\uc0c1\uc744 \uc644\ud654\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib197\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib197\"><span class=\"anchor-text\">[197]<\/span><\/a>. \uac8c\ub2e4\uac00,\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc5d1\uc18c\uc880\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/exosome\">\uc5d1\uc18c\uc19c<\/a>\u00a0\uc800\uc0b0\uc18c\uc131 \uace8\uc218\uc5d0\uc11c \uc720\ub798\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc911\uac04\uc5fd \uc904\uae30\uc138\ud3ec\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/mesenchymal-stem-cell\">\uc911\uac04\uc5fd\uc904\uae30\uc138\ud3ec<\/a>\u00a0CIRI\ub85c \uc720\ubc1c\ub41c \uc2e0\uacbd \ubc1c\uc5f4\uc99d\uc744 \uc644\ud654\ud558\uae30 \uc704\ud574 \uc18c\uad50\uc138\ud3ec M1\/M2 \ud45c\ud604\ud615\uc744 \uc870\uc808\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib198\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib198\"><span class=\"anchor-text\">[198]<\/span><\/a>. \uc800\uc0b0\uc18c\uc99d \uc0ac\uc804 \uc870\uac74\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud6c4\uac01 \uc810\ub9c9\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/olfactory-mucosa\">\ud6c4\uac01\uc810\ub9c9<\/a>\u00a0\uc911\uac04\uc5fd\uc904\uae30\uc138\ud3ec\ub294 \uc800\uc0b0\uc18c\uc99d \uc720\ubc1c\uc778\uc790-1\u03b1\ub97c \ud65c\uc131\ud654\uc2dc\ucf1c \ub1cc\ud5c8\ud608\ub85c \uc778\ud55c \uc18c\uad50\uc138\ud3ec\uc758 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4(pyroptosis)\uc640 \uc544\ud3ec\ud1a0\uc2dc\uc2a4(apoptosis)\ub97c \uc5b5\uc81c\ud568\uc73c\ub85c\uc368 CIRI\ub97c \uac10\uc18c\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib199\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib199\"><span class=\"anchor-text\">[199]<\/span><\/a>.<\/p>\n<p id=\"p0145\">pyroptosis\uc758 \uc2e4\ud589\uc790\ub85c\uc11c GSDMD\ub294 IS \uce58\ub8cc\ub97c \uc704\ud55c \uc774\uc0c1\uc801\uc778 \ubd84\uc790 \ud45c\uc801\uc785\ub2c8\ub2e4. \uadf8\ub7ec\ub098 GSDMD \uc5b5\uc81c\uc81c\uc5d0 \ub300\ud55c \ud604\uc7ac \uc5f0\uad6c\ub294 \uc544\uc9c1 \ucd08\uae30 \ub2e8\uacc4\uc5d0 \uc788\uc73c\uba70, \ud5c8\ud608\uc131 \ub1cc\uc878\uc911 \uce58\ub8cc\uc5d0\uc11c GSDMD \uc5b5\uc81c\uc81c\uc758 \ud6a8\ub2a5\uc5d0 \ub300\ud55c \uc99d\uac70\uac00 \ubd80\uc871\ud569\ub2c8\ub2e4. \ucd5c\uadfc \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \uc77c\ubd80 \ucc9c\uc5f0 \uc2dd\ubb3c \uc131\ubd84\uc740 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uacbd\ub85c\ub97c \uc870\uc808\ud558\uc5ec IS\ub97c \uce58\ub8cc\ud560 \uc218 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.<\/p>\n<\/section>\n<section id=\"sec0095\">\n<h2 id=\"sect0115\" class=\"u-h4 u-margin-l-top u-margin-xs-bottom\">5. \ucc9c\uc5f0\ubb3c\uc740 \uc0c8\ub85c\uc6b4 \ubc1c\uc5f4 \uc5b5\uc81c\uc81c\ub85c\uc11c IS \uce58\ub8cc\uc758 \uc7a0\uc7ac\uc801 \ud6c4\ubcf4\uac00 \ub429\ub2c8\ub2e4.<\/h2>\n<p id=\"p0150\">\ucc9c\uc5f0\ubb3c\uc740 \ub2e4\uc131\ubd84, \ub2e4\ud45c\uc801, \ub2e4\ucc44\ub110, \uc800\ub3c5\uc131 \ub4f1\uc758 \uc7a5\uc810\uc73c\ub85c \uc778\ud574 \ub1cc\uacbd\uc0c9\/\ub1cc\ud5c8\ud608-\uc7ac\uad00\ub958\uc758 \uc608\ubc29 \ubc0f \uce58\ub8cc\uc5d0 \uc0c1\ub2f9\ud55c \uc774\uc810\uc744 \uac16\uace0 \uc788\uc73c\uba70, \uc751\uc6a9 \uc804\ub9dd\ub3c4 \uc88b\uc2b5\ub2c8\ub2e4. \ud604\uc7ac \ub1cc\uacbd\uc0c9\/CIRI\uc758 \uc608\ubc29 \ubc0f \uce58\ub8cc\uc5d0 \uc788\uc5b4 \ub2e4\uc591\ud55c \ubcf4\ud638 \uba54\ucee4\ub2c8\uc998\uc744 \ud3ec\ud568\ud558\ub294 \ucc9c\uc5f0\ubb3c\uc5d0 \ub300\ud55c \uc5f0\uad6c\uac00 \uc810\ucc28 \uc99d\uac00\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc774 \uc139\uc158\uc5d0\uc11c\ub294 \ucc9c\uc5f0\ubb3c, \ub3d9\ubb3c \ub610\ub294 \uc138\ud3ec \ubaa8\ub378, \ud22c\uc5ec \ubc29\ubc95, \ud22c\uc5ec \uc6a9\ub7c9, \uce58\ub8cc \uc2dc\uac04, \ud6a8\uacfc \ubc0f \uce58\ub8cc \uba54\ucee4\ub2c8\uc998(\uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c)\uc744 \uc694\uc57d\ud558\uc5ec \uc548\uc804\ud558\uace0 \ud6a8\uacfc\uc801\uc774\uba70 \ub3c5\uc131\uc774 \ub0ae\uc740 \ucc9c\uc5f0 \uc2dd\ubb3c \uc131\ubd84\uc744 \uc2e0\uc18d\ud558\uac8c \uac80\uc0c9\ud560 \uc218 \uc788\ub294 \uc774\ub860\uc801 \uadfc\uac70\ub97c \uc81c\uacf5\ud569\ub2c8\ub2e4. , IS\/CIRI\uc758 \uc608\ubc29 \ubc0f \uce58\ub8cc\ub97c \uc704\ud574 \ubc1c\uc5f4\uc99d\uc744 \uc870\uc808\ud569\ub2c8\ub2e4.<\/p>\n<section id=\"sec0100\">\n<h3 id=\"sect0120\" class=\"u-h4 u-margin-m-top u-margin-xs-bottom\">5.1. \ucc9c\uc5f0 \uc2dd\ubb3c \uc131\ubd84<\/h3>\n<div>\n<p id=\"p0155\">\ucc9c\uc5f0 \uc2dd\ubb3c \uc131\ubd84\uc758 \uc8fc\uc694 \uad6c\uc870\ub294 \ub2e4\uc74c\uacfc \uac19\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#fig0015\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"fig0015\"><span class=\"anchor-text\">\uadf8\ub9bc 3<\/span><\/a>.<\/p>\n<figure id=\"fig0015\" class=\"figure text-xs\"><img decoding=\"async\" src=\"https:\/\/ars.els-cdn.com\/content\/image\/1-s2.0-S0753332222013889-gr3.jpg\" alt=\"Fig. 3\" height=\"397\" aria-describedby=\"cap0015\" \/><\/p>\n<ol class=\"u-margin-s-bottom\">\n<li><a class=\"anchor download-link u-font-sans u-display-inline anchor-default\" title=\"\uace0\ud574\uc0c1\ub3c4 \uc774\ubbf8\uc9c0 \ub2e4\uc6b4\ub85c\ub4dc(208KB)\" href=\"https:\/\/ars.els-cdn.com\/content\/image\/1-s2.0-S0753332222013889-gr3_lrg.jpg\" target=\"_blank\" rel=\"noopener\" download=\"\"><span class=\"anchor-text\">\ub2e4\uc6b4\ub85c\ub4dc :\u00a0<span class=\"download-link-title\">\uace0\ud574\uc0c1\ub3c4 \uc774\ubbf8\uc9c0 \ub2e4\uc6b4\ub85c\ub4dc(208KB)<\/span><\/span><\/a><\/li>\n<li><a class=\"anchor download-link u-font-sans u-display-inline anchor-default\" title=\"\uc804\uccb4 \ud06c\uae30 \uc774\ubbf8\uc9c0 \ub2e4\uc6b4\ub85c\ub4dc\" href=\"https:\/\/ars.els-cdn.com\/content\/image\/1-s2.0-S0753332222013889-gr3.jpg\" target=\"_blank\" rel=\"noopener\" download=\"\"><span class=\"anchor-text\">\ub2e4\uc6b4\ub85c\ub4dc :\u00a0<span class=\"download-link-title\">\uc804\uccb4 \ud06c\uae30 \uc774\ubbf8\uc9c0 \ub2e4\uc6b4\ub85c\ub4dc<\/span><\/span><\/a><\/li>\n<\/ol>\n<p id=\"sp0015\"><span class=\"label\">\uadf8\ub9bc 3<\/span>. \ucc9c\uc5f0 \uc2dd\ubb3c \uc131\ubd84\uc758 \uc8fc\uc694 \uad6c\uc870.<\/p>\n<\/figure>\n<\/div>\n<section id=\"sec0105\">\n<h4 id=\"sect0125\" class=\"u-margin-m-top u-margin-xs-bottom\">5.1.1. \uac00\uc2a4\ud2b8\ub85c\ub518(GAS)<\/h4>\n<p id=\"p0160\">GAS\ub294 \ud5c8\ube0c\uc5d0\uc11c \ucd94\ucd9c\ud55c \ub2e4\uae30\ub2a5 \ud654\ud569\ubb3c\ub85c,\u00a0<em><a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c Gastrodia elata\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/gastrodia-elata\">\uac00\uc2a4\ud2b8\ub85c\ub514\uc544 \uc5d8\ub77c\ud0c0<\/a><\/em>, \ub2e4\uc591\ud55c\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc57d\ub9ac\ud559\uc801 \ud65c\ub3d9\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/pharmacological-activity\">\uc57d\ub9ac\ud559\uc801 \ud65c\uc131<\/a>, \ud56d\uc0b0\ud654 \ubc0f \ud56d\uc5fc\uc99d \ud65c\uc131\uacfc \uac19\uc740. \ub610\ud55c GAS\ub294 \uce74\uc2a4\ud30c\uc81c-3 \uc808\ub2e8, IL-18 \ubc0f IL-1\u03b2\ub97c \ube44\ub86f\ud55c \uc138\ud3ec\uc0ac\uba78 \ucd09\uc9c4 \uc778\uc790\ub97c \uc870\uc808\ud558\uc5ec \ub1cc\ud5c8\ud608-\uc7ac\uad00\ub958 \uc99d\uc0c1\uc744 \ud06c\uac8c \uac10\uc18c\uc2dc\ud0a4\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uc5ec\ub7ec \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 GAS\ub294 \ub1cc \ud5c8\ud608\uc131 \uc190\uc0c1\uc744 \uac1c\uc120\ud558\uace0 \ub1cc\uc758 \uc218\uc900\uc744 \uac10\uc18c\uc2dc\ud0a4\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud65c\uc131 \uc0b0\uc18c\uc885\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/reactive-oxygen-species\">\ud65c\uc131\uc0b0\uc18c\uc885<\/a>\u00a0\uadf8\ub9ac\uace0\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc5fc\uc99d\uc131 \uc0ac\uc774\ud1a0\uce74\uc778\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/inflammatory-cytokine\">\uc5fc\uc99d\uc131 \uc0ac\uc774\ud1a0\uce74\uc778<\/a>\u00a0\uc0dd\uc950\uc5d0\uc11c\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib200\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib200\"><span class=\"anchor-text\">[200]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib201\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib201\"><span class=\"anchor-text\">[201]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib202\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib202\"><span class=\"anchor-text\">[202]<\/span><\/a>. Luet al. GAS\uac00 NLRP3\/caspase-1 \ucd95\uc744 \ud45c\uc801\uc73c\ub85c \uc0bc\uc544 \uc2ec\uc7a5 \ubbf8\uc138\ud608\uad00 \ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uacfc \uad00\ub828\ub41c \ubc1c\uc5f4\uc99d\uc744 \uac1c\uc120\ud560 \uc218 \uc788\uc74c\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib203\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib203\"><span class=\"anchor-text\">[203]<\/span><\/a>. GAS\ub294\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc2e0\uacbd \uae30\ub2a5\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/nervous-system-physiology\">\uc2e0\uacbd \uae30\ub2a5<\/a>\u00a0\uc810\uc218\ub97c \ub9e4\uae30\uace0 \ud06c\uae30\ub97c \uc904\uc785\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub1cc\uacbd\uc0c9\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/brain-infarction\">\ub1cc\uacbd\uc0c9<\/a>. \ud55c\ud3b8, GAS\ub294 NLRP3, \uc5fc\uc99d \uc778\uc790(IL-1\u03b2, IL-18) \ubc0f \uc808\ub2e8\ub41c \uce74\uc2a4\ud30c\uc81c-1\uc744 \ud558\ud5a5 \uc870\uc808\ud558\uc5ec \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc5b5\uc81c\ud588\uc2b5\ub2c8\ub2e4. \ub610\ud55c GAS\ub294 lncRNA NEAT1\/miR-22-3p \ucd95\uc744 \uc870\uc808\ud558\uc5ec \ud5c8\ud608-\uc7ac\uad00\ub958\ub85c \uc720\ubc1c\ub41c \uc2e0\uacbd \uc138\ud3ec \uc5fc\uc99d\uc744 \uc57d\ud654\uc2dc\ucf30\uc2b5\ub2c8\ub2e4. GAS\ub294 lncRNA NEAT1\/miR-22-3p \ucd95\uc744 \uc870\uc808\ud558\uc5ec \ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc744 \ud06c\uac8c \uc57d\ud654\uc2dc\ucf30\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib204\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib204\"><span class=\"anchor-text\">[204]<\/span><\/a>. \ub530\ub77c\uc11c GAS\ub294 \uc7a0\uc7ac\uc801\uc778 \uc218\ub2e8\uc73c\ub85c \uc0ac\uc6a9\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc57d\ubb3c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/chemotherapeutic-agent\">\uc758\uc57d\ud488<\/a>\u00a0CIRI \uce58\ub8cc\ub97c \uc704\ud574<\/p>\n<\/section>\n<section id=\"sec0110\">\n<h4 id=\"sect0130\" class=\"u-margin-m-top u-margin-xs-bottom\">5.1.2. \ud0c4\uc2dc\ub17c IIA<\/h4>\n<p id=\"p0165\"><a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c Tanshinone IIA\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/tanshinone-iia\">\ud0c4\uc2dc\ub17c IIA<\/a>\u00a0\uc758 \uc8fc\uc694 \ud65c\uc131 \uc131\ubd84\uc785\ub2c8\ub2e4\u00a0<em><a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c Salvia miltiorrhiza\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/salvia-miltiorrhiza\">\uc0d0\ube44\uc5b4 miltiorrhiza<\/a><\/em>. \uc2ec\ud608\uad00\uacc4 \uc9c8\ud658 \uce58\ub8cc\uc5d0 \ub110\ub9ac \uc0ac\uc6a9\ub418\uba70,\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub1cc\ud608\uad00 \uc9c8\ud658\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/cerebrovascular-disease\">\ub1cc\ud608\uad00 \uc9c8\ud658<\/a>\u00a0\ud56d\uc0b0\ud654 \ud6a8\uacfc\uc640 \ud608\uc561 \uc21c\ud658 \uac1c\uc120 \ud6a8\uacfc \ub54c\ubb38\uc785\ub2c8\ub2e4. Caiet al.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib205\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib205\"><span class=\"anchor-text\">[205]<\/span><\/a>\u00a0\ud0c4\uc2dc\ub17c IIA\ub294 NLRP3 \uc5fc\uc99d \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\uc5d0\uc11c IL-1\u03b2 \ubc0f IL-18\uc758 \ubc1c\ud604\uc744 \ud6a8\uacfc\uc801\uc73c\ub85c \uac10\uc18c\uc2dc\ucf30\uc73c\uba70 \uadf8 \ud6a8\uacfc\ub294 \uc6a9\ub7c9 \uc758\uc874\uc801\uc774\ub77c\ub294 \uac83\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub294 \ud0c4\uc2dc\ub17c IIA\uac00 NLRP3 \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\uc758 \ud65c\uc131\ud654\ub97c \uc5b5\uc81c\ud568\uc73c\ub85c\uc368 \ub1cc\uc878\uc911 \ud6c4 BV-2 \uc138\ud3ec\uc758 \uc0b0\uc18c-\ud3ec\ub3c4\ub2f9 \uacb0\ud54d\/\uc7ac\uad00\ub958 \uc190\uc0c1\uc744 \uac10\uc18c\uc2dc\ud0a8\ub2e4\ub294 \uac83\uc744 \uc758\ubbf8\ud569\ub2c8\ub2e4.<\/p>\n<\/section>\n<section id=\"sec0115\">\n<h4 id=\"sect0135\" class=\"u-margin-m-top u-margin-xs-bottom\">5.1.3. \ub808\uc624\ub204\ub9b0<\/h4>\n<p id=\"p0170\"><a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c Leonurine\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/leonurine\">\ub808\uc624\ub204\ub9b0<\/a>\u00a0~\uc5d0\u00a0<em><a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c Leonuri\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/leonurus\">\ub808\uc624\ub204\ub9ac<\/a><\/em><em>\u00a0\ud5c8\ube0c<\/em>\u00a0\ub9cc\uc131 \ub1cc\ud5c8\ud608\uc774 \uc788\ub294 \uc950\uc758 \ud559\uc2b5\ub2a5\ub825\uacfc \uae30\uc5b5\ub825\uc744 \ud5a5\uc0c1\uc2dc\ud0a4\uace0, NLRP3\uc758 \ubc1c\ud604\uc744 \uac10\uc18c\uc2dc\ucf30\uc2b5\ub2c8\ub2e4. \ud56d\uc5fc\uc99d \ud6a8\uacfc\ub97c \ud1b5\ud574 \uc2e0\uacbd\uc744 \ubcf4\ud638\ud558\ub294 \ubaa9\uc801\uc744 \ub2ec\uc131\ud560 \uc218 \uc788\uc744 \uac83\uc73c\ub85c \ucd94\uce21\ub41c\ub2e4. NLRP3\uc758 \ud65c\uc131\ud654\ub294 \uce74\uc2a4\ud30c\uc81c-1 \uc804\uad6c\uccb4\uc758 \uce74\uc2a4\ud30c\uc81c-1\ub85c\uc758 \uc804\ud658\uc744 \ucd09\uc9c4\ud558\uace0, IL-1\u03b2 \ubc0f IL-18\uc758 \uc0dd\uc131\uc744 \ucd09\uc9c4\uc2dc\ucf1c \uc77c\ub828\uc758 \uc5fc\uc99d \ubc18\uc751\uc744 \uc77c\uc73c\ud0a8\ub2e4. \ub808\uc624\ub204\ub9b0\uc740 \ub1cc \uc870\uc9c1\uc758 \uc5fc\uc99d \ubc18\uc751\uc744 \uac10\uc18c\uc2dc\ud0a4\uace0, \uc138\ud3ec\uc758 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc5b5\uc81c\ud558\uc5ec \uc2e0\uacbd\ud559\uc801 \uacb0\ud54d \uc810\uc218\ub97c \uac10\uc18c\uc2dc\ud0a4\uba70, \uc6b0\uc218\ud55c \uc2e0\uacbd \ubcf4\ud638 \ud6a8\uacfc\ub97c \ub098\ud0c0\ub0bc \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib206\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib206\"><span class=\"anchor-text\">[206]<\/span><\/a>.<\/p>\n<\/section>\n<section id=\"sec0120\">\n<h4 id=\"sect0140\" class=\"u-margin-m-top u-margin-xs-bottom\">5.1.4. \ud30c\uc624\ub2c8\ud50c\ub85c\ub9b0<\/h4>\n<p id=\"p0175\"><a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c Paeoniflorin\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/paeoniflorin\">\ud30c\uc624\ub2c8\ud50c\ub85c\ub9b0<\/a>\u00a0\uc758 \uc8fc\uc694 \uad6c\uc131 \uc694\uc18c\uc5d0\uc11c \ube44\ub86f\ub429\ub2c8\ub2e4.\u00a0<em><a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c Paeoniae radix rubra\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/radix-paeoniae-rubra\">Paeoniae \uae30\uc218 \ub8e8\ube0c\ub77c<\/a><\/em>. Paeoniflorin\uc740 \ucd1d\uae00\ub8e8\ucf54\uc0ac\uc774\ub4dc\uc758 \uc8fc\uc694 \ud65c\uc131 \uc131\ubd84\uc785\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ubaa8\ub780\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/paeonia\">\ubaa8\ub780<\/a>\u00a0(TGP), \uc774\ub294 \ub610\ud55c \uc6b0\uc218\ud55c \ud56d\uc5fc\uc99d \ubc0f \uba74\uc5ed \uc870\uc808 \ud65c\uc131\uc744 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib207\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib207\"><span class=\"anchor-text\">[207]<\/span><\/a>. TGP\uc640 paeoniflorin\uc740 \ub610\ud55c \ub2e4\uc74c\uacfc \uac19\uc740 \ub2e4\uc591\ud55c \uc57d\ub9ac \ud65c\uc131\uc744 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc9c4\uacbd\uc81c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/antispasmodic\">\uc9c4\uacbd\uc81c<\/a>,\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc9c4\ud1b5\uc81c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/anodyne\">\uc9c4\ud1b5\uc81c<\/a>, \uadf8\ub9ac\uace0\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud608\uad00 \ud655\uc7a5\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/vasodilatation\">\ud608\uad00 \ud655\uc7a5<\/a>\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib208\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib208\"><span class=\"anchor-text\">[208]<\/span><\/a>. Zulifiya Ekemuet al. \uae09\uc131 \ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958 \ud6c4\uc5d0 \ub1cc\uc758 \uc18c\uad50\uc138\ud3ec\uc640 \uc2e0\uacbd \uc5f4\ubd84\ud574\uc99d\uc758 \ud65c\uc131\ud654\uac00 \uba85\ubc31\ud558\uace0 NLRP3\uc758 \ud65c\uc131\ud654\uac00 \uc99d\uac00\ud558\uba70 Caspase-1\uacfc IL-1\u03b2\uac00 \uc0c1\ud5a5 \uc870\uc808\ub41c\ub2e4\ub294 \uac83\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib209\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib209\"><span class=\"anchor-text\">[209]<\/span><\/a>. Paeoniflorin\uc740 \uc2e0\uacbd \uae30\ub2a5 \uc810\uc218\ub97c \ud06c\uac8c \uac10\uc18c\uc2dc\ucf30\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub1cc\uacbd\uc0c9 \ud06c\uae30\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/brain-infarction-size\">\ub1cc\uacbd\uc0c9 \ud06c\uae30<\/a>, Iba1 \ubc1c\ud604\uc774 \ud06c\uac8c \ud558\ud5a5 \uc870\uc808\ub418\uc5c8\uc73c\uba70 \uc2e0\uacbd \uc0c1\ud0dc\uac00 \ud06c\uac8c \uac1c\uc120\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ub610\ud55c paeoniflorin \uac1c\uc785 \ud6c4 NLRP3, Caspase-1 \ubc0f IL-1\u03b2\uc758 \ubc1c\ud604\uc774 \uc720\uc758\ud558\uac8c \uac10\uc18c\ud588\uc2b5\ub2c8\ub2e4. Paeoniflorin\uc740 \uc18c\uad50\uc138\ud3ec\uc758 \ud65c\uc131\ud654\ub97c \uac10\uc18c\uc2dc\ud0a4\uace0, \ub274\ub7f0\uc758 \ubc1c\uc5f4\uc99d\uc744 \uc5b5\uc81c\ud558\uba70, NLRP3 \ubc0f Caspase-1\uc758 \ud65c\uc131\ud654\ub97c \uc5b5\uc81c\ud568\uc73c\ub85c\uc368 ACI \ub9e4\uac1c \uc2e0\uacbd\ud559\uc801 \uc190\uc0c1\uc744 \uac1c\uc120\ud560 \uc218 \uc788\ub2e4\uace0 \uc81c\uc548\ub429\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib209\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib209\"><span class=\"anchor-text\">[209]<\/span><\/a>.<\/p>\n<\/section>\n<section id=\"sec0125\">\n<h4 id=\"sect0145\" class=\"u-margin-m-top u-margin-xs-bottom\">5.1.5. \ubd80\ud2f8\ud504\ud0c8\ub77c\uc774\ub4dc<\/h4>\n<p id=\"p0180\"><span class=\"small-caps\">\uc5d8<\/span>-\ubd80\ud2f8\ud504\ud0c8\ub77c\uc774\ub4dc\ub294 \uba3c\uc800 \uc720\ucc44\uacfc \uc57c\ucc44 \uc528\uc557\uc5d0\uc11c \ubd84\ub9ac\ub418\uc5c8\uc73c\uba70 \ub098\uc911\uc5d0 \uc778\uacf5\uc801\uc73c\ub85c \ud569\uc131\ub420 \uc218 \uc788\uc5c8\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ubd80\ud2f8\ud504\ud0c8\ub77c\uc774\ub4dc\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/butylphthalide\">\ubd80\ud2f8\ud504\ud0c8\ub77c\uc774\ub4dc<\/a>\u00a0\uc7ac\uad6c\uc131\ud560 \uc218 \uc788\uc744 \ubfd0\ub9cc \uc544\ub2c8\ub77c \ub3c5\ud2b9\ud55c \uc774\uc911 \uc5ed\ud560\uc744 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ubbf8\uc138\uc21c\ud658\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/microcirculation\">\ubbf8\uc138 \uc21c\ud658<\/a>\u00a0\ud5c8\ud608 \uc7ac\uad00\ub958\ub97c \uc99d\uac00\uc2dc\ucf1c\uc11c\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud608\uad00 \uad6c\uc870\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/blood-vessel\">\ud608\uad00 \uad6c\uc870<\/a>, \ud608\uad00 \uc9c1\uacbd \ud68c\ubcf5, \ud5c8\ud608\uc131 \ubd80\uc704\uc758 \ud608\ub958\ub7c9 \uc99d\uac00 \ubc0f \uc8fc\ubcc0 \ud608\uad00 \uc218 \uc99d\uac00\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ubbf8\uc138\ud608\uad00\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/microvessel\">\ubbf8\uc138\ud608\uad00<\/a>\ubfd0\ub9cc \uc544\ub2c8\ub77c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\ub97c \ubcf4\ud638\ud558\uace0 \uc138\ud3ec \uc0ac\uba78\uc744 \uac10\uc18c\uc2dc\ucf1c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uad6c\uc870\uc758 \uc644\uc804\uc131\uc744 \ubcf4\ud638\ud558\uace0 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ubcf5\ud569 \ud6a8\uc18c IV\uc758 \ud65c\uc131\uc744 \ud5a5\uc0c1\uc2dc\ud0a4\uba70 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 ATP \ud6a8\uc18c\uc758 \ud65c\uc131\uc744 \ud5a5\uc0c1\uc2dc\ud0a4\uace0 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\uc758 \uc548\uc815\uc131\uc744 \uc720\uc9c0\ud569\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ub9c9\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/mitochondrial-membrane\">\ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ub9c9<\/a>\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib210\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib210\"><span class=\"anchor-text\">[210]<\/span><\/a>. \ucd5c\uc2e0 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \ubd80\ud2f8\ud504\ud0c8\ub77c\uc774\ub4dc\ub294 NLRP3 \uc778\ud50c\ub77c\ub9c8\uc19c \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub97c \ud1b5\ud574 \uc6a9\ub7c9 \uc758\uc874\uc801\uc73c\ub85c CIRI \uc950\uc758 \ubc1c\uc5f4\uc99d\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/section>\n<section id=\"sec0130\">\n<h4 id=\"sect0150\" class=\"u-margin-m-top u-margin-xs-bottom\">5.1.6. \ube0c\ub808\ube44\uc2a4\uce74\ud540<\/h4>\n<p id=\"p0185\"><a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c Breviscapine\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/breviscapine\">\ube0c\ub808\ube44\uc2a4\uce74\ud540<\/a>\u00a0\uc5d0\uc11c \ucd94\ucd9c\ub429\ub2c8\ub2e4\u00a0<em><a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c Erigeron breviscapus\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/erigeron-breviscapus\">Erigeron breviscapus<\/a><\/em>\u00a0(\ubc34\ud2b8.) \uc190. -\ub9c8\uc988. \ube0c\ub808\ube44\uc2a4\uce74\ud540\uc740 \ub2e4\uc74c\uc758 \ud63c\ud569\ubb3c\uc785\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc2a4\ucfe0\ud154\ub77c\ub9b0\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/scutellarin\">\uc2a4\ucfe0\ud154\ub77c\ub9b0<\/a>\u00a0\uc8fc\ub85c \uc2a4\ucfe0\ud154\ub77c\ub9b0\uc774 \ud568\uc720\ub418\uc5b4 \uc788\uc73c\uba70 \uc18c\ub7c9\uc758 \uc2a4\ucfe0\ud154\ub77c\ub9b0\uc774 \ud568\uc720\ub418\uc5b4 \uc788\uc5b4 \ub1cc\ud608\uad00 \ud655\uc7a5, \ub1cc\ud608\uad00 \uc800\ud56d \uac10\uc18c, \ub1cc\ud608\ub958 \uc99d\uac00, \ubbf8\uc138\uc21c\ud658 \uac1c\uc120, \uc800\ud56d\uc791\uc6a9 \ub4f1\uc758 \uae30\ub2a5\uc744 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud608\uc18c\ud310 \uc751\uc9d1\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/thrombocyte-aggregation\">\ud608\uc18c\ud310 \uc751\uc9d1<\/a>. \ucd5c\uadfc \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \ube0c\ub808\ube44\uc2a4\uce74\ud540\uc740 \ub1cc\uc5d0\uc11c NLRP3 \uc5fc\uc99d \uc138\ud3ec\uc758 \ud65c\uc131\ud654\ub97c \uc720\uc758\ud558\uac8c \uc5b5\uc81c\ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud574\ub9c8\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/hippocampus\">\ud574\ub9c8<\/a>\u00a0CCI \uc950\uc758 \uacbd\uc6b0 Caspase 1, IL-6 \ubc0f IL-1\u03b2 \ub2e8\ubc31\uc9c8\uc758 \ubc1c\ud604\uc744 \ud558\ud5a5 \uc870\uc808\ud558\uace0 Caspase-3 \ub2e8\ubc31\uc9c8\uc758 \ud65c\uc131\ud654\ub97c \uc5b5\uc81c\ud558\uba70\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc2e0\uacbd \uc138\ud3ec\uc0ac\uba78\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/neuroapoptosis\">\uc2e0\uacbd \uc138\ud3ec \uc0ac\uba78<\/a>. \uc774\ub294 \ube0c\ub808\ube44\uc2a4\uce74\ud540\uc774 CCI \uc950\uc758 \uc778\uc9c0 \uae30\ub2a5\uc744 \ud06c\uac8c \ud5a5\uc0c1\uc2dc\ud0a4\uace0 \ud5c8\ud608\uc131 \ub274\ub7f0\uc758 \ubcd1\ub9ac\ud559\uc801 \uc190\uc0c1\uc744 \uac10\uc18c\uc2dc\ud0ac \uc218 \uc788\uc74c\uc744 \uc2dc\uc0ac\ud558\uba70, \uadf8 \uba54\ucee4\ub2c8\uc998\uc740 \ub1cc \uc870\uc9c1\uc758 NLRP3 \uc778\ud50c\ub77c\ub9c8\uc19c \ud65c\uc131\ud654 \ubc0f \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uacbd\ub85c\uc758 \uc5b5\uc81c\uc640 \uad00\ub828\uc774 \uc788\uc744 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib211\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib211\"><span class=\"anchor-text\">[211]<\/span><\/a>.<\/p>\n<\/section>\n<section id=\"sec0135\">\n<h4 id=\"sect0155\" class=\"u-margin-m-top u-margin-xs-bottom\">5.1.7. \ub808\uc2a4\ubca0\ub77c\ud2b8\ub864<\/h4>\n<p id=\"p0190\"><a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub808\uc2a4\ubca0\ub77c\ud2b8\ub864\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/resveratrol\">\ub808\uc2a4\ubca0\ub77c\ud2b8\ub864<\/a>\u00a0\ube44\ud50c\ub77c\ubcf4\ub178\uc774\ub4dc\uc774\ub2e4\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud3f4\ub9ac\ud398\ub180 \ud654\ud569\ubb3c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/polyphenol-derivative\">\ud3f4\ub9ac\ud398\ub180 \ud654\ud569\ubb3c<\/a>. \ucc98\uc74c\uc73c\ub85c \ubfcc\ub9ac\uc5d0\uc11c \ubd84\ub9ac\ub418\uc5c8\uc2b5\ub2c8\ub2e4.\u00a0<em><a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c Veratrum\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/veratrum\">\ubca0\ub77c\ud2b8\ub8f8<\/a><\/em><em>\u00a0\ud070\uaf43<\/em>, \ub808\uc2a4\ubca0\ub77c\ud2b8\ub864\uc740 700\uac1c \uc774\uc0c1\uc758 \uc2dd\ubb3c\uc5d0\uc11c \ubc1c\uacac\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \ub808\uc2a4\ubca0\ub77c\ud2b8\ub864\uc740 \ub1cc\uacbd\uc0c9\uc5d0\uc11c \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\ub97c \uc870\uc808\ud558\uace0 \uc5fc\uc99d\uc744 \uc5b5\uc81c\ud558\uba70 \ub1cc\ub97c \uac1c\uc120\ud558\ub294 \ub370 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc2e0\uacbd \ubcf4\ud638\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/neuroprotection\">\uc2e0\uacbd\ubcf4\ud638<\/a>. \ub808\uc2a4\ubca0\ub77c\ud2b8\ub864\uc740 \uc8fc\ub85c \uc18c\uad50\uc138\ud3ec NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4, Caspase-1 \ubc0f ZO-1\uc758 \uc870\uc808\uc744 \ud1b5\ud574 \ud5c8\ud608-\uc7ac\uad00\ub958 \ub1cc \uc870\uc9c1\uc758 \ubc1c\uc5f4\uc99d\uc744 \uc870\uc808\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib212\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib212\"><span class=\"anchor-text\">[212]<\/span><\/a>.<\/p>\n<\/section>\n<section id=\"sec0140\">\n<h4 id=\"sect0160\" class=\"u-margin-m-top u-margin-xs-bottom\">5.1.8. \uc0b4\ube44\uc544\ub180\uc0b0(SAFI)<\/h4>\n<p id=\"p0195\">\ucd5c\uadfc \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 SAFI\ub294 \uc2e0\uacbd\ud559\uc801 \uacb0\uc190 \uc810\uc218\ub97c \ud06c\uac8c \uc99d\uac00\uc2dc\ud0a4\uace0 \uacbd\uc0c9\ub7c9\uc744 \uac10\uc18c\uc2dc\ud0a4\uba70 \uc870\uc9c1\ud559\uc801 \uc190\uc0c1\uc744 \uc57d\ud654\uc2dc\ud0a4\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub300\ub1cc \ud53c\uc9c8\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/cerebral-cortex\">\ub300\ub1cc \ud53c\uc9c8<\/a>\u00a0MCAO\/R \ubaa8\ub378\uc758 \uc2e0\uacbd \uc138\ud3ec \uc0ac\uba78\uc740 \uc2e0\uacbd \uc138\ud3ec \uc0dd\uc874\ub825\uc744 \uc99d\uac00\uc2dc\ud0a4\uace0 OGD \ubaa8\ub378\uc758 \uc2e0\uacbd \uc138\ud3ec \uc0ac\uba78\uc744 \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4. SAFI\ub294 \ub610\ud55c \uc18c\uad50\uc138\ud3ec \ubd84\uadf9 \ud328\ud134\uc744 M1 \uc720\uc0ac \ud45c\ud604\ud615\uc5d0\uc11c M2 \uc720\uc0ac \ud45c\ud604\ud615\uc73c\ub85c \ub9ac\ubaa8\ub378\ub9c1\ud558\uace0 \uc2dc\ud5d8\uad00 \ub0b4 \ubc0f \uc0dd\uccb4 \ub0b4\uc5d0\uc11c NLRP3 \uc778\ud50c\ub77c\ub9c8\uc880\/\ubc1c\uc0b0\uc18c \uad00\ub828 \ub2e8\ubc31\uc9c8\uc758 \ubc1c\ud604\uacfc NLRP3 \uc778\ud50c\ub77c\ub9c8\uc880\uc758 \ud65c\uc131\ud654\ub97c \uc5b5\uc81c\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub294 SAFI\uac00 \uc2e0\uacbd \uc138\ud3ec\uc0ac\uba78\uc744 \uac10\uc18c\uc2dc\ud0a4\uace0, \uc18c\uad50\uc138\ud3ec \ud45c\ud604\ud615\uc744 M1\uc5d0\uc11c M2\ub85c \uc774\ub3d9\uc2dc\ud0a4\uace0, \uc18c\uad50\uc138\ud3ec\uc5d0\uc11c NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4\/pyroptotic \ucd95\uc744 \uc5b5\uc81c\ud568\uc73c\ub85c\uc368 \uc2e0\uacbd \ubcf4\ud638 \ud6a8\uacfc\ub97c \ubc1c\ud718\ud560 \uc218 \uc788\uc74c\uc744 \uc2dc\uc0ac\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib213\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib213\"><span class=\"anchor-text\">[213]<\/span><\/a>.<\/p>\n<\/section>\n<section id=\"sec0145\">\n<h4 id=\"sect0165\" class=\"u-margin-m-top u-margin-xs-bottom\">5.1.9. \ud788\ud53c\ub458\ub9b0<\/h4>\n<p id=\"p0200\"><a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud788\ud53c\ub458\ub9b0\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/hispidulin\">\ud788\ud53c\ub458\ub9b0<\/a>\u00a0\ub294\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud50c\ub77c\ubcf4\ub178\uc774\ub4dc\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/flavonoid\">\ud50c\ub77c\ubcf4\ub178\uc774\ub4dc<\/a>\u00a0\ub2e4\uc591\ud55c \uc57d\ub9ac\ud559\uc801 \ud2b9\uc131\uc744 \uc9c0\ub2cc \ud654\ud569\ubb3c\uc774\uba70 \ub9ce\uc740 \uc8fc\uc694 \ud65c\uc131 \uc131\ubd84 \uc911 \ud558\ub098\uc785\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud55c\uc57d\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/chinese-herbal-medicine\">\ud55c\uc57d\uc7ac<\/a>. \ud788\ud53c\ub458\ub9b0\uc740 \ud56d\uc0b0\ud654\uc81c,\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud56d\uc9c4\uade0\uc81c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/antifungal-agent\">\ud56d\uc9c4\uade0\uc81c<\/a>,\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud56d\uc885\uc591\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/anticarcinogen\">\ud56d\uc885\uc591<\/a>, \ud56d\uace8\ub2e4\uacf5\uc99d, \ud56d\uc5fc\uc99d \ubc0f \ud56d\ub3cc\uc5f0\ubcc0\uc774 \ud2b9\uc131. \ucd5c\uadfc \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \ud788\ud53c\ub458\ub9b0\uc740 \uac1c\uc120\ub41c \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc2e0\uacbd\ud559\uc801 \uc99d\uc0c1\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/neurologic-disease\">\uc2e0\uacbd\ud559\uc801 \uc99d\uc0c1<\/a>\u00a0IRI \ud6c4 \uc950\uc758 \uacbd\uc0c9 \ud06c\uae30\uc640\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub1cc\ubd80\uc885\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/brain-edema\">\ub1cc\ubd80\uc885<\/a>. \uae30\uacc4\uc801\uc73c\ub85c \ud788\ud53c\ub458\ub9b0\uc740 AMPK\/GSK3\u03b2 \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub97c \uc870\uc808\ud558\uc5ec NLRP3 \ub9e4\uac1c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc5b5\uc81c\ud568\uc73c\ub85c\uc368 \uc0dd\uccb4 \ub0b4 \ubc0f \uc2dc\ud5d8\uad00 \ub0b4\uc5d0\uc11c \uc2e0\uacbd \ubcf4\ud638 \ud6a8\uacfc\ub97c \ubc1c\ud718\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib214\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib214\"><span class=\"anchor-text\">[214]<\/span><\/a>.<\/p>\n<\/section>\n<section id=\"sec0150\">\n<h4 id=\"sect0170\" class=\"u-margin-m-top u-margin-xs-bottom\">5.1.10. \uc544\uc2a4\ud2b8\ub77c\uac08\ub85c\uc0ac\uc774\ub4dc IV<\/h4>\n<p id=\"p0205\"><em><a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c Astragali Radix\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/astragalus-root\">\ud669\uae30 \uae30\uc218<\/a><\/em>\u00a0\uacb0\ud54d\uc744 \ubcf4\ucda9\ud558\uace0 \ube44\uc7a5\uacfc \uc704\ub97c \ud2bc\ud2bc\ud558\uac8c \ud558\uba70 \ud608\uc561\uc21c\ud658\uc744 \ucd09\uc9c4\ud558\uace0 \ud608\uc561\uc21c\ud658\uc744 \ucd09\uc9c4\ud558\uba70 \ub2e4\uc74c\uacfc \uac19\uc740 \uc99d\uc0c1\uc744 \uce58\ub8cc\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c Qi \uacb0\ud54d\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/qi-deficiency\">\uae30 \uacb0\ud54d<\/a>\u00a0\uadf8\ub9ac\uace0 \ud608\uc561 \uacb0\ud54d\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib215\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib215\"><span class=\"anchor-text\">[215]<\/span><\/a>.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc544\uc2a4\ud2b8\ub77c\uac08\ub85c\uc0ac\uc774\ub4dc IV\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/astragaloside-iv\">\uc544\uc2a4\ud2b8\ub77c\uac08\ub85c\uc0ac\uc774\ub4dc IV<\/a>\u00a0\uc758 \uc8fc\uc694 \ud65c\uc131 \uad6c\uc131 \uc694\uc18c \uc911 \ud558\ub098\uc785\ub2c8\ub2e4.\u00a0<em>\ud669\uae30 \uae30\uc218<\/em>\u00a0\uadf8\ub9ac\uace0\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub2e8\ub7c9\uccb4\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/monomer\">\ub2e8\uc704\uccb4<\/a>\u00a0\uad6c\uc131 \uc694\uc18c\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud669\uae30\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/astragalus\">\ubcf5\uc0ac \ubf08<\/a>\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc0ac\ud3ec\ub2cc\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/saponin\">\uc0ac\ud3ec\ub2cc<\/a>. \ud669\uae30\uc758 \ud488\uc9c8\uc744 \ud14c\uc2a4\ud2b8\ud558\ub294 \ud45c\uc900\uc73c\ub85c \uc790\uc8fc \uc0ac\uc6a9\ub429\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib216\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib216\"><span class=\"anchor-text\">[216]<\/span><\/a>. \uc544\uc2a4\ud2b8\ub77c\uac08\ub85c\uc0ac\uc774\ub4dc IV\uc5d0\ub294 \ub2e4\uc591\ud55c \uc885\ub958\uac00 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc0dd\ubb3c\ud559\uc801 \ud65c\ub3d9\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/biological-activity\">\uc0dd\ubb3c\ud559\uc801 \ud65c\ub3d9<\/a>, \uc5f0\uad6c \ubc94\uc704\uc5d0\ub294 \ub1cc, \uac04, \uc2ec\uc7a5, \ud3d0, \uc2e0\uc7a5, \uc704, \ub0b4\uc7a5, \ud608\uad00 \ub4f1 \uc5ec\ub7ec \uc7a5\uae30 \ubc0f \uc870\uc9c1\uc774 \ud3ec\ud568\ub429\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib217\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib217\"><span class=\"anchor-text\">[217]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib218\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib218\"><span class=\"anchor-text\">[218]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib219\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib219\"><span class=\"anchor-text\">[219]<\/span><\/a>\u00a0\ud56d\uc5fc\uc99d, \ud56d\ubc14\uc774\ub7ec\uc2a4, \ud56d\uc544\ud3ec\ud1a0\uc2dc\uc2a4, \ucd09\uc9c4 \ub4f1\uc758 \uc0dd\ubb3c\ud559\uc801 \ud65c\uc131\uc744 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc138\ud3ec \uc99d\uc2dd\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/cell-proliferation\">\uc138\ud3ec \uc99d\uc2dd<\/a>, \uaddc\uc81c\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud1a0\ub07c \uc9c8\ubcd1\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/rabbit-disease\">\ud1a0\ub07c \uc9c8\ubcd1<\/a>, \ud608\ub2f9 \uc870\uc808, \ub178\ud654 \uc9c0\uc5f0, \uc554 \uc5b5\uc81c\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib217\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib217\"><span class=\"anchor-text\">[217]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib218\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib218\"><span class=\"anchor-text\">[218]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib219\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib219\"><span class=\"anchor-text\">[219]<\/span><\/a>. \uc6b0\ub9ac\uc758 \uc774\uc804 \uc5f0\uad6c\uc5d0\uc11c\ub294 \uc544\uc2a4\ud2b8\ub77c\uac08\ub85c\uc0ac\uc774\ub4dc IV\uac00 IS \uce58\ub8cc\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud558\ub294 \uc7a0\uc7ac\uc801\uc778 \uc2e0\uacbd \ubcf4\ud638\uc81c\uc784\uc744 \ud655\uc778\ud588\uc2b5\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, \ud608\uc561\ub1cc\uad00\ubb38 \ubcf4\ud638, \uc5d0\ub108\uc9c0 \ub300\uc0ac \uac1c\uc120, \uc2e0\uacbd\uc138\ud3ec \uc0ac\uba78 \uc5b5\uc81c, \uc5fc\uc99d\ubc18\uc751 \uc5b5\uc81c, \uc0b0\ud654\uc2a4\ud2b8\ub808\uc2a4 \uc5b5\uc81c, \uc2e0\uacbd\ubcf4\ud638 \ud6a8\uacfc\ub97c \ubc1c\ud718\ud558\uc5ec \ub1cc\ud5c8\ud608\uc744 \uac1c\uc120\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib220\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib220\"><span class=\"anchor-text\">[220]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib221\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib221\"><span class=\"anchor-text\">[221]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib222\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib222\"><span class=\"anchor-text\">[222]<\/span><\/a>. pyroptosis\uc758 \uad00\uc810\uc5d0\uc11c Tang et al. \uc950\uc758 \ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958 \ub3d9\uc548 NLRP3 \uc778\ud50c\ub77c\ub9c8\uc880\uc774 \ud65c\uc131\ud654\ub418\uc5c8\uc73c\uba70, NLRP3 \uc778\ud50c\ub77c\ub9c8\uc880\uc744 \uc5b5\uc81c\ud558\uac70\ub098 \uadf8 \ub2e4\uc6b4\uc2a4\ud2b8\ub9bc \uce74\uc2a4\ud30c\uc81c-1\uc744 \uc5b5\uc81c\ud558\uba74 \uc950 \uc190\uc0c1\uc5d0\uc11c \ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958\ub97c \uc644\ud654\ud560 \uc218 \uc788\uc74c\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib223\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib223\"><span class=\"anchor-text\">[223]<\/span><\/a>. \uc544\uc2a4\ud2b8\ub77c\uac08\ub85c\uc0ac\uc774\ub4dc IV\ub294 \uc2e0\uacbd\ud559\uc801 \uacb0\uc190 \uc810\uc218\ub97c \uac10\uc18c\uc2dc\ud0a4\uace0, \ub1cc\uacbd\uc0c9\uc758 \uc591\uc744 \uac10\uc18c\uc2dc\ud0a4\uba70, \ub1cc \uc870\uc9c1\uc5d0\uc11c NLRP3, Caspase-1, pro-IL-1\u03b2, IL-1\u03b2, pro-IL-18 \ubc0f IL-18\uc758 \ub2e8\ubc31\uc9c8 \uc218\uc900\uc744 \uac10\uc18c\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. , \uc778\uc0b0\ud654\ub41c NF-\u03baB \ub2e8\ubc31\uc9c8\uc758 \ubc1c\ud604\uc744 \uc5b5\uc81c\ud569\ub2c8\ub2e4. \uc774\ub294 \uc544\uc2a4\ud2b8\ub77c\uac08\ub85c\uc0ac\uc774\ub4dc IV\uac00 \ud56dCIRI \ud6a8\uacfc\ub97c \uac00\uc9c0\uba70 \uadf8 \uba54\ucee4\ub2c8\uc998\uc774 NF-\u03baB\uc758 \uc5b5\uc81c\uc640 \uad00\ub828\uc774 \uc788\uc744 \uc218 \uc788\uc74c\uc744 \uc2dc\uc0ac\ud569\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub2e8\ubc31\uc9c8 \uc778\uc0b0\ud654\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/protein-phosphorylation\">\ub2e8\ubc31\uc9c8 \uc778\uc0b0\ud654<\/a>\u00a0NLRP3 \uc778\ud50c\ub77c\ub9c8\uc880 \ud65c\uc131\ud654 \uc5b5\uc81c\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib223\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib223\"><span class=\"anchor-text\">[223]<\/span><\/a>. Li et al. \ub610\ud55c \uc544\uc2a4\ud2b8\ub77c\uac08\ub85c\uc2dc\ub4dc IV\uac00 \uc2e0\uc0dd\uc544 \uc950\uc758 \uc800\uc0b0\uc18c\uc99d-\ud5c8\ud608\ub85c \uc778\ud55c \ub1cc \uc190\uc0c1\uc744 \uac10\uc18c\uc2dc\ud0ac \uc218 \uc788\uace0, \uc2e0\uc0dd\uc544 \uc950\uc758 \uc800\uc0b0\uc18c\uc131 \ud5c8\ud608\uc131 \ub1cc \uc870\uc9c1\uacfc HT22 \ud574\ub9c8 \ub274\ub7f0\uc758 \uc5fc\uc99d \ubc18\uc751\uc744 \uc5b5\uc81c\ud560 \uc218 \uc788\ub2e4\ub294 \uac83\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub294 MMP-9 \ub9e4\uac1c NLRP3\/\ub97c \uc870\uc808\ud568\uc73c\ub85c\uc368 \ubc1c\ud718\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. Caspase-1 \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib224\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib224\"><span class=\"anchor-text\">[224]<\/span><\/a>.<\/p>\n<\/section>\n<section id=\"sec0155\">\n<h4 id=\"sect0175\" class=\"u-margin-m-top u-margin-xs-bottom\">5.1.11. \ud30c\ub099\uc2a4 \uc0bc\uce60\uc778\uc0bc \uc0ac\ud3ec\ub2cc(PNS)<\/h4>\n<p id=\"p0210\"><em>Notoginseng Radix Et Rhizoma<\/em>\u00a0\ub9d0\ub9b0 \ubfcc\ub9ac\uc774\uace0\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ubfcc\ub9ac\uc904\uae30\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/rhizome\">\ubfcc\ub9ac\uc904\uae30<\/a>\u00a0~\uc758\u00a0<em><a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c Panax\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/panax\">\ud30c\ub099\uc2a4<\/a><\/em><em>\u00a0\ub0ab\ud1a0\uae34\uc13c(\ubc84\ud06c)<\/em>\u00a0\ud608\uc561, \uc2ec\ud608\uad00, \uc2e0\uacbd\uacc4 \ubc0f \uba74\uc5ed\uccb4\uacc4\uc5d0\uc11c \uc57d\ub9ac\ud559\uc801 \ud65c\uc131\uc744 \uac16\ub294 FH Chen\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib225\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib225\"><span class=\"anchor-text\">[225]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib226\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib226\"><span class=\"anchor-text\">[226]<\/span><\/a>. PNS\ub294 \ub2e4\uc591\ud55c \ub2e8\ub7c9\uccb4\uc131 \uc0ac\ud3ec\ub2cc\uc744 \ud568\uc720\ud558\uace0 \uc788\ub294 \uc8fc\uc131\ubd84\uc73c\ub85c \uc124\uc0ac\uc774\ud1b5\uc8fc\uc0ac\uc81c \ub4f1\uc758 \uc81c\uc81c\ub294 \uc2ec\ud608\uad00 \ubc0f \ub1cc\ud608\uad00 \uc9c8\ud658\uc758 \uc608\ubc29 \ubc0f \uce58\ub8cc\uc5d0 \ub110\ub9ac \uc0ac\uc6a9\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib227\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib227\"><span class=\"anchor-text\">[227]<\/span><\/a>. \uc6b0\ub9ac\uc758 \uc774\uc804 \uc5f0\uad6c\uc640 \uae30\uc874 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 PNS\ub294 \ub2e4\uc74c\uacfc \uac19\uc740 \ud5c8\ud608\uc131 \ub1cc \uc190\uc0c1\uc5d0 \ub2e4\uc591\ud55c \uc57d\ub9ac\ud559\uc801 \ud6a8\uacfc\uac00 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud56d\ud608\uc804\uc81c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/antithrombotic\">\ud56d\ud608\uc804\uc81c<\/a>, \ud56d\uc5fc\uc99d, \ud56d\uc0b0\ud654, \ub1cc\uc2e0\uacbd\uc138\ud3ec \uc0ac\uba78\uc5b5\uc81c, \ud608\uc561\ub1cc\uc7a5\ubcbd \uc190\uc0c1 \uac1c\uc120\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib228\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib228\"><span class=\"anchor-text\">[228]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib229\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib229\"><span class=\"anchor-text\">[229]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib230\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib230\"><span class=\"anchor-text\">[230]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib231\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib231\"><span class=\"anchor-text\">[231]<\/span><\/a>. \uc774\ub294 PNS\uac00 \uc5ec\ub7ec \ud45c\uc801\uc744 \ud1b5\ud574 \ub1cc \ud5c8\ud608\uc5d0\uc11c \ubcf4\ud638 \uc5ed\ud560\uc744 \ud560 \uc218 \uc788\uc74c\uc744 \uc2dc\uc0ac\ud569\ub2c8\ub2e4. \ucd5c\uadfc \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 PNS\ub294 NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4\uc758 \ud65c\uc131\ud654\ub97c \uc5b5\uc81c\ud558\uace0 \uc120\ud0dd\uc801\uc73c\ub85c \ucd09\uc9c4\ud560 \uc218 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ubbf8\ud1a0\ud30c\uc9c0\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/mitophagy\">\ubbf8\ud1a0\ud30c\uc9c0<\/a>\u00a0\uc950\uc758 \ub300\ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958 \ub3d9\uc548. \ubbf8\ud1a0\ud30c\uc9c0\uc758 \uc5b5\uc81c\ub294 NLRP3 \uc778\ud50c\ub77c\ub9c8\uc19c\uc5d0 \ub300\ud55c PNS\uc758 \uc5b5\uc81c \ud6a8\uacfc\ub97c \uc5ed\uc804\uc2dc\ud0ac \uc218 \uc788\uc73c\uba70, \uc774\ub294 \ubbf8\ud1a0\ud30c\uc9c0\uac00 \ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958\uc5d0\uc11c NLRP3 \uc778\ud50c\ub77c\ub9c8\uc19c \ud65c\uc131\ud654\uc5d0 \ub300\ud55c PNS\uc758 \uc5b5\uc81c \ud6a8\uacfc\ub97c \ub9e4\uac1c\ud55c\ub2e4\ub294 \uac83\uc744 \ub098\ud0c0\ub0c5\ub2c8\ub2e4. \ub610\ud55c, \uc950\uc758 \ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958 \ub3d9\uc548 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\uc758 PINK1 \ubc0f Parkin \ub2e8\ubc31\uc9c8 \uc218\uc900\uc774 \uc99d\uac00\ud588\uc73c\uba70, PNS\ub294 \ub1cc \uc870\uc9c1\uc758 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\uc5d0\uc11c PINK1 \ubc0f Parkin \ub2e8\ubc31\uc9c8\uc758 \uc218\uc900\uc744 \ub354\uc6b1 \uc99d\uac00\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub294 PNS\uac00 PINK1\/Parkin \uacbd\ub85c\ub97c \ud1b5\ud574 \ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958\uc5d0\uc11c \ubbf8\ud1a0\ud30c\uc9c0\ub97c \ucd09\uc9c4\ud560 \uc218 \uc788\uc74c\uc744 \uc2dc\uc0ac\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib232\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib232\"><span class=\"anchor-text\">[232]<\/span><\/a>. \uc694\uc57d\ud558\uba74, PNS\ub294 PINK1\/Parkin \uacbd\ub85c\ub97c \ud1b5\ud574 \uc120\ud0dd\uc801\uc73c\ub85c \ubbf8\ud1a0\ud30c\uc9c0\ub97c \ucd09\uc9c4\ud558\uace0, \ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958\uc5d0\uc11c NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4\uc758 \ud65c\uc131\ud654\ub97c \uc5b5\uc81c\ud558\uace0, \ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc744 \uc644\ud654\ud569\ub2c8\ub2e4.<\/p>\n<\/section>\n<\/section>\n<section id=\"sec0160\">\n<h3 id=\"sect0180\" class=\"u-h4 u-margin-m-top u-margin-xs-bottom\">5.2. \ucc9c\uc5f0 \uc2dd\ubb3c \ucd94\ucd9c\ubb3c<\/h3>\n<section id=\"sec0165\">\n<h4 id=\"sect0185\" class=\"u-margin-m-top u-margin-xs-bottom\">5.2.1. \ud0c0\uc624\ud64d\uc2dc\uc6b0\ud0d5(THSWD)<\/h4>\n<p id=\"p0215\">THSWD\ub294 \ud608\uc561 \uc21c\ud658\uc744 \ucd09\uc9c4\ud558\uace0 \uc81c\uac70\ud558\ub294 \uace0\uc804\uc801\uc778 \ucc98\ubc29 \uc911 \ud558\ub098\uc785\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud608\uc561 \uc815\uccb4\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/blood-stasis\">\ud608\uc561 \uc815\uccb4<\/a>, \uccad\ub098\ub77c Wu Qian\uc758 &quot;\ud669\uae08 \uac70\uc6b8&quot;\uc774 \ub9cc\ub4e0 \ud608\uc561 \uc815\uccb4\ub97c \uc81c\uac70\ud558\uace0 \uc0c8\ub85c\uc6b4 \ud608\uc561\uc744 \uc7ac\uc0dd\ud569\ub2c8\ub2e4. \ud604\uc7ac \uc57d\ub9ac\ud559 \uc5f0\uad6c\uc5d0\uc11c\ub294 THSWD\uc758 \uc8fc\uc694 \ud65c\uc131 \uc131\ubd84\uc774 \ub2e4\uc74c\uacfc \uac19\uc740 \uac83\uc73c\ub85c \ud655\uc778\ub418\uc5c8\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud398\ub8f0\uc0b0\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/ferulic-acid\">\ud398\ub8f0\uc0b0<\/a>,\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc787\uaf43\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/safflower\">\uc787<\/a>\u00a0\ub178\ub780\uc0c9, \uadf8\ub9ac\uace0\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub2e4\ub2f9\ub958\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/glycan\">\ub2e4\ub2f9\ub958<\/a>. \uadf8 \uc911 \ud398\ub8f0\ub9b0\uc0b0\uc740 \ud608\uc18c\ud310 \uc751\uc9d1 \uc5b5\uc81c, \ud56d\ud608\uc804, \ud56d\uc5fc\uc99d, \ud56d\uc0b0\ud654 \ub4f1 \uc57d\ub9ac\uc791\uc6a9\uc774 \uc788\ub2e4. \uc787\uaf43 \ud669\uc0c9\uc5d0\ub294 \ud56d \ub1cc \ud5c8\ud608, \ud56d \uc2ec\uadfc \ud5c8\ud608, \ud56d \ud608\uc804\uc99d, \ud56d\uc0b0\ud654, \ud56d \uc885\uc591 \ubc0f \uae30\ud0c0 \ud6a8\uacfc\uac00 \uc788\uc2b5\ub2c8\ub2e4. Zhouet al. THSWD\ub294 \ub1cc\ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1 \ud6c4 \uc2e0\uacbd\ud559\uc801 \uacb0\uc190 \uae30\ub2a5, \ub1cc\uacbd\uc0c9\ub7c9 \ubc0f \ub1cc \uc870\uc9c1 \ud615\ud0dc\ub97c \uac1c\uc120\ud558\uace0 DRP1, NLRP3, Caspase-1 \ubc0f IL-1 \u03b2 \ub2e8\ubc31\uc9c8\uc758 \uc218\uc900\uc744 \ud06c\uac8c \uac10\uc18c\uc2dc\ud0a4\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib233\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib233\"><span class=\"anchor-text\">[233]<\/span><\/a>. \uc774\ub294 \ub1cc\uacbd\uc0c9\uc5d0 \ub300\ud55c THSWD\uc758 \uce58\ub8cc \ud6a8\uacfc\uac00 \ubc1c\uc5f4\uc99d\uacfc \uad00\ub828\ub41c DRP1\/NLRP3 \uacbd\ub85c\uc758 \uc5b5\uc81c\uc640 \uad00\ub828\uc774 \uc788\uc74c\uc744 \ub098\ud0c0\ub0c5\ub2c8\ub2e4. \ucd94\uac00 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 THSWD \uadf8\ub8f9\uc5d0\uc11c IL-1\u03b2 \ubc0f IL-18\uc758 \ud568\ub7c9\uc774 \ud06c\uac8c \uac10\uc18c\ud588\uc73c\uba70 NLRP3, Caspase-1, Caspase-1 p10, ASC, TXNIP \ubc0f GSDMD \uc218\uc900\uc774 \uac10\uc18c\ud55c \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uc2e0\ud638\uc804\ub2ec \uacbd\ub85c\uc758 \uac80\ucd9c\uc740 THSWD\uac00 HMGB1\/RAGE, TLR4\/NF-\u03baB,\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c p38 MAPK\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/p38-mitogen-activated-protein-kinase\">p38 \ub9f5<\/a>\u00a0\ubc18\uadf8\ub9bc\uc790\uc5d0\ub294 JNK\uac00 \uc788\uc2b5\ub2c8\ub2e4. \uc694\uc57d\ud558\uba74, THSWD\ub294 MCAO\/R \uc950\uc758 \uc5fc\uc99d \ubc18\uc751 \uc218\uc900\uc744 \uac10\uc18c\uc2dc\ud0a4\uace0 MCAO\/R \uc950\uc758 NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4 \ud65c\uc131\ud654\ub97c \uc5b5\uc81c\ud558\uba70 GSDMD\ub97c \ud558\ud5a5 \uc870\uc808\ud569\ub2c8\ub2e4. THSWD\ub294 HMGB1\/TLR4\/NF-kB \ubc0f MAPK \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub97c \uc5b5\uc81c\ud568\uc73c\ub85c\uc368 \uc601\ud5a5\uc744 \ubc1b\uc744 \uc218 \uc788\ub294 \ubc1c\uc5f4\uc99d\uc744 \uc5b5\uc81c\ud558\ub294 \ud6a8\uacfc\uac00 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib234\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib234\"><span class=\"anchor-text\">[234]<\/span><\/a>.<\/p>\n<\/section>\n<section id=\"sec0170\">\n<h4 id=\"sect0190\" class=\"u-margin-m-top u-margin-xs-bottom\">5.2.2. \ub098\uc624\uc2e0\uce6d \ucea1\uc290(NXQC)<\/h4>\n<p id=\"p0220\">NXQC\uc758 \uc8fc\uc131\ubd84\uc740\u00a0<em><a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c Diospyros kaki\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/persimmon\">\ub514\uc624\uc2a4\ud53c\ub85c\uc2a4 \uce74\ud0a4<\/a><\/em>\u00a0\ud230\ube0c(\uac10\uc78e). \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \uac10\uc78e \ucd94\ucd9c\ubb3c\uc5d0\ub294 \ud50c\ub77c\ubcf4\ub178\uc774\ub4dc, \uc720\uae30\uc0b0 \ubc0f\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ucfe0\ub9c8\ub9b0\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/coumarin\">\ucfe0\ub9c8\ub9b0<\/a>\u00a0\ud56d\uc5fc\uc99d, \ud56d\uc0b0\ud654 \ud6a8\uacfc\uac00 \uc788\ub294 \uae30\ud0c0 \ud654\ud559 \ubb3c\uc9c8,\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud56d\uace0\ud608\uc555\uc81c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/antihypertensive-agent\">\ud56d\uace0\ud608\uc555\uc81c<\/a>, \ud608\uc911 \uc9c0\uc9c8 \uc800\ud558, \uac1c\uc120\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud608\uad00 \ud3c9\ud65c\uadfc\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/vascular-smooth-muscle\">\ud608\uad00 \ud3c9\ud65c\uadfc<\/a>\u00a0\uae30\ub2a5\uacfc\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud608\uc5ed\ud559\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/hemodynamic\">\ud608\uc5ed\ud559\uc801<\/a>\u00a0\uae30\ub2a5. \uc774 \uc57d\ubb3c\uc740 \uc2ec\ud608\uad00 \ubc0f \ub1cc\ud608\uad00 \uc9c8\ud658 \uce58\ub8cc\uc5d0 \ub110\ub9ac \uc0ac\uc6a9\ub418\uc5b4 \uc654\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib235\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib235\"><span class=\"anchor-text\">[235]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib236\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib236\"><span class=\"anchor-text\">[236]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib237\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib237\"><span class=\"anchor-text\">[237]<\/span><\/a>. \uae30\uc874 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 NXQC\ub294 \ud6a8\uacfc\uc801\uc73c\ub85c \uac1c\uc120\ud560 \uc218 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub1cc\ub3d9\ub9e5\uacbd\ud654\uc99d\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/cerebral-atherosclerosis\">\ub1cc\ub3d9\ub9e5\uacbd\ud654\uc99d<\/a>\u00a0\ub1cc\ud5c8\ud608\ub85c \uc778\ud55c \uc2e0\uacbd \uc190\uc0c1\uc744 \ubcf4\ud638\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib238\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib238\"><span class=\"anchor-text\">[238]<\/span><\/a>. Min et al. NXQC\ub294 \ub1cc\ud5c8\ud608 \ud6c4 \ud559\uc2b5 \ub2a5\ub825 \uc800\ud558\ub97c \ud6a8\uacfc\uc801\uc73c\ub85c \uac1c\uc120\ud558\uace0 \ub1cc\uc758 \ud65c\ub3d9\uc744 \uc99d\uac00\uc2dc\ud0ac \uc218 \uc788\uc74c\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc288\ud37c\uc625\uc0ac\uc774\ub4dc \ub514\uc2a4\ubba4\ud0c0\uc81c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/superoxide-dismutase\">\uacfc\uc0b0\ud654\ubb3c \uc81c\uac70\ud6a8\uc18c<\/a>\u00a0\uadf8\ub9ac\uace0\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc816\uc0b0 \ud0c8\uc218\uc18c\ud6a8\uc18c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/lactate-dehydrogenase\">\uc816\uc0b0\ud0c8\uc218\uc18c\ud6a8\uc18c<\/a>, GSH\uc758 \ud568\ub7c9\uc744 \ub192\uc774\uace0,\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ub9d0\ub860\ub514\uc54c\ub370\ud788\ub4dc\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/malonaldehyde\">\ub9d0\ub860\ub514\uc54c\ub370\ud788\ub4dc<\/a>. NXQC\ub294 \ub610\ud55c \ud574\ub9c8\uc5d0\uc11c ASC, NLRP3 \ubc0f Caspase-1 \ub2e8\ubc31\uc9c8\uc744 \ud558\ud5a5\uc870\uc808\ud558\uace0 IL-18 \ubc0f IL-1\u03b2 \ud568\ub7c9\uc744 \ud06c\uac8c \uac10\uc18c\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uadf8\ub4e4\uc740 \ub610\ud55c \uc800\ube4c\uc758 \ud608\uc18c\ud310 \ub0b4\ud53c \uc138\ud3ec \ubd80\ucc29 \ubd84\uc790-1 \uc591\uc131 \uc138\ud3ec\uac00 NXQC \uac1c\uc785 \ud6c4 \uc720\uc758\ud558\uac8c \uc99d\uac00\ud588\ub2e4\ub294 \uac83\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc138\ud3ec\uac04 \uc811\ud569\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/cell-junction\">\uc138\ud3ec\uac04 \uc811\ud569<\/a>\u00a0\ube61\ube61\ud588\uc5b4\uc694. NXQC\ub294 \ud615\ud0dc\ub97c \ud6a8\uacfc\uc801\uc73c\ub85c \ubcf4\ud638\ud560 \uc218 \uc788\ub2e4\uace0 \uc81c\uc548\ub429\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud574\ub9c8 CA1 \uc601\uc5ed\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/sommers-sector\">\ud574\ub9c8 CA1 \uc601\uc5ed<\/a>\u00a0\uc800\ube4c\uc758 \ub1cc\ud608\uad00 \uae30\ub2a5\uc744 \ubcf4\ud638\ud558\uace0 \ub1cc\ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc744 \uc5b5\uc81c\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib239\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib239\"><span class=\"anchor-text\">[239]<\/span><\/a>.<\/p>\n<\/section>\n<section id=\"sec0175\">\n<h4 id=\"sect0195\" class=\"u-margin-m-top u-margin-xs-bottom\">5.2.3. \ubd80\uc591\ud658\uc624\ud0d5(BYHWD) \ubc0f \uadf8 \ubcc0\ud615\ubb3c<\/h4>\n<p id=\"p0225\">BYHWD\ub294 \uc720\uba85\ud569\ub2c8\ub2e4\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc804\ud1b5 \uc911\uad6d \uc758\ud559\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/traditional-chinese-medicine\">\uc804\ud1b5\uc801\uc778 \uc911\uad6d \uc57d<\/a>\u00a0\ub1cc\uc878\uc911 \uce58\ub8cc\uc5d0 \uc0ac\uc6a9\ub418\ub294 \uacf5\uc2dd. \ucc98\ubc29\uc740 \uccad\ub098\ub77c \uc655\uccad\uc778(\u738b\u6176\u4ec1)\uc758 \u300e\uc758\ud559\uad50\uc815\u300f\uc5d0 \ucc98\uc74c\uc73c\ub85c \uae30\ub85d\ub418\uc5b4 \uc788\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib240\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib240\"><span class=\"anchor-text\">[240]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib241\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib241\"><span class=\"anchor-text\">[241]<\/span><\/a>. \uae30\ub97c \uc790\uc591\ud558\uace0 \ud608\uc561\uc744 \ud65c\uc131\ud654\uc2dc\ud0a4\ub294 \ucc98\ubc29\uc758 \ud0c1\uc6d4\ud55c \ub300\ud45c\uc790\uc785\ub2c8\ub2e4. \uae30(\u6c23)\ub97c \ud2bc\ud2bc\ud558\uac8c \ud558\uace0 \ud608\uc561\uc21c\ud658\uc744 \ucd09\uc9c4\ud558\uba70 \uacc1\uac00\uc9c0\ub97c \uc900\uc124\ud558\ub294 \uae30\ub2a5\uc774 \uc788\uc2b5\ub2c8\ub2e4. \uc99d\uac70 \uae30\ubc18 \uc758\ud559 \uc5f0\uad6c\ub97c \ud1b5\ud574 \uc6b0\uc218\ud55c \uc784\uc0c1 \ud6a8\uacfc\uac00 \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib242\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib242\"><span class=\"anchor-text\">[242]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib243\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib243\"><span class=\"anchor-text\">[243]<\/span><\/a>. \uc774\uc804 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 BYHWD\ub294\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ubc30\ub2f9\uccb4\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/glycoside\">\ubc30\ub2f9\uccb4<\/a>\u00a0\uc2e0\uacbd \uae30\ub2a5 \uc7a5\uc560\ub97c \uac1c\uc120\ud558\uace0 \uc2e0\uacbd \uc190\uc0c1\uc744 \uc904\uc774\uba70 \uc2e0\uacbd \ubc1c\uc5f4\uc99d\uc744 \uc5b5\uc81c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. BYHWD \ubc30\ub2f9\uccb4\ub294 BYHWD\uc5d0\uc11c \ucd94\ucd9c\ub41c \ud65c\uc131 \uc131\ubd84\uc73c\ub85c \uc8fc\ub85c \uc544\uc2a4\ud2b8\ub77c\uac08\ub85c\uc0ac\uc774\ub4dc IV, \ud30c\uc624\ub2c8\ud50c\ub85c\ub9b0 \ubc0f\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc544\ubbf8\uadf8\ub2ec\ub9b0\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/amygdalin\">\uc544\ubbf8\uadf8\ub2ec\ub9b0<\/a>. \uc2e0\uc7a5\uc744 \ud2bc\ud2bc\ud558\uac8c \ud558\uace0 \ud608\uc561\uc744 \ud65c\uc131\ud654\uc2dc\ud0a4\ub294 \uc8fc\uc694 \uc57d\ub9ac\ud65c\uc131\uc131\ubd84\uc73c\ub85c \ub1cc\ud5c8\ud608\uc131 \uc2e0\uacbd\uc190\uc0c1\uc744 \uce58\ub8cc\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib244\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib244\"><span class=\"anchor-text\">[244]<\/span><\/a>. \ub610\ud55c, \uc6b0\ub9ac\ub294 BYHWD \uae00\ub9ac\ucf54\uc2dc\ub4dc\uac00 NLRP3 \ub9e4\uac1c \ud45c\uc900 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uacbd\ub85c\uc758 NLRP3, ASC, pro-caspase-1, caspase-1 \ubc0f IL-1\u03b2 \ub2e8\ubc31\uc9c8\uc758 \ubc1c\ud604\uc744 \uc720\uc758\ud558\uac8c \uc5b5\uc81c\ud55c\ub2e4\ub294 \uac83\uc744 \uad00\ucc30\ud588\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib209\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib209\"><span class=\"anchor-text\">[209]<\/span><\/a>. \uc694\uc57d\ud558\uba74, BYHWD \ubc30\ub2f9\uccb4\ub294 CIRI \uc774\ud6c4\uc758 \uc2e0\uacbd \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc5b5\uc81c\ud568\uc73c\ub85c\uc368 \uc2e0\uacbd \ubcf4\ud638 \ud6a8\uacfc\ub97c \ubc1c\ud718\ud558\ub294\ub370, \uc774\ub294 NLRP3\uc5d0 \uc758\ud55c \uace0\uc804\uc801 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uacbd\ub85c\uc758 \uc870\uc808\uacfc \ubc00\uc811\ud55c \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4. \uac8c\ub2e4\uac00 \ub871\uc988\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c Decoction\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/decoction\">\ub2ec\uc784<\/a>\u00a0\ub294 BYHWD\uac00 \uac70\uba38\ub9ac\uc640\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c Achyranthes\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/achyranthes\">\uc544\ud0a4\ub780\ud14c\uc2a4<\/a>\u00a0\uc2dc\ucd94\uc548\uc2dc\uc2a4. \uc218\ub144 \ub3d9\uc548 \uae09\uc131 \ub1cc\uc878\uc911\uc758 \uc784\uc0c1 \uce58\ub8cc\uc5d0 \uc0ac\uc6a9\ub418\uc5b4 \uc654\uc73c\uba70 \ud6a8\uacfc\uac00 \ub9e4\uc6b0 \uc88b\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib245\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib245\"><span class=\"anchor-text\">[245]<\/span><\/a>. \ucd5c\uadfc \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 Longzhi \ub2ec\uc784\uc740 CIRI \ud6c4 \uc950\uc758 \uc2e0\uacbd \uc99d\uc0c1\uc744 \uac1c\uc120\ud558\uace0 \ub1cc \uc870\uc9c1\uc758 \uc2e0\uacbd \uc138\ud3ec \uc0c1\ud0dc\ub97c \uc720\uc9c0\ud558\uba70 \ub1cc\uacbd\uc0c9\uc758 \uc591\uc744 \uc904\uc774\ub294 \ub370 \uba85\ubc31\ud55c \ud6a8\uacfc\uac00 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uc138\ud3ec \ubc1c\uc5f4\uc758 \uac1c\uc785 \uce21\uba74\uc5d0\uc11c Longzhi Decoction\uc740 CIRI \ud6c4 \uc950\uc758 \uc99d\uc0c1\uc744 \uac1c\uc120\ud558\uace0 \ubcf4\ud638\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc2e0\uacbd \uc138\ud3ec \uc190\uc0c1\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/nerve-cell-lesion\">\uc2e0\uacbd \uc138\ud3ec \uc190\uc0c1<\/a>\u00a0Caspase-1 \ubc0f IL-18 \ub2e8\ubc31\uc9c8\uc758 \ubc1c\ud604\uc744 \ud558\ud5a5 \uc870\uc808\ud558\uc5ec \uc190\uc0c1 \ud6c4\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib245\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib245\"><span class=\"anchor-text\">[245]<\/span><\/a>.<\/p>\n<\/section>\n<section id=\"sec0180\">\n<h4 id=\"sect0200\" class=\"u-margin-m-top u-margin-xs-bottom\">5.2.4. Yiqi Huoxue \ucc98\ubc29(YQHXP)<\/h4>\n<p id=\"p0230\">YQHXP\ub294 \ub2e4\uc74c\uc73c\ub85c \uad6c\uc131\ub429\ub2c8\ub2e4.\u00a0<em>\uc548\uc824\ub9ac\uce74\uc5d0 \uc2dc\ub128\uc2dc\uc2a4 \uae30\uc218, \ud669\uae30 \uae30\uc218,\u00a0<\/em><em><a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c Chuanxiong Rhizoma\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/ligusticum-chuanxiong-extract\">Chuanxiong Rhizoma<\/a><\/em><em>, \uc804\uac08\uc790\ub9ac, Leonuri Herba, Acori Tatarinowii Rhizoma, Borneolum Syntheticum<\/em>, \uc88b\uc740 \uc784\uc0c1 \uacb0\uacfc\ub97c \uc5bb\uc5c8\uc2b5\ub2c8\ub2e4\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib246\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib246\"><span class=\"anchor-text\">[246]<\/span><\/a>. \ub3d9\ubb3c \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 YQHXP\ub294 \uc950\uc758 \uc2e0\uacbd \uae30\ub2a5 \uc810\uc218\uc640 \ub1cc\uacbd\uc0c9 \ube44\uc728\uc744 \uac1c\uc120\ud558\uace0 \ub1cc \uc870\uc9c1\uc5d0\uc11c IL-1\u03b2, TNF-\u03b1 \ubc0f IL-18\uc758 \uc218\uc900\uacfc IL-18\uc758 \uc0c1\ub300\uc801 \ubc1c\ud604\uc744 \uac10\uc18c\uc2dc\ud0a4\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c P2RX7\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/p2rx7\">P2RX7<\/a>, \ub300\ub1cc \ud5c8\ud608\uc131 \ubc18\uc74c\uc601 \uc870\uc9c1\uc758 Caspase-1, Caspase-11 \ubc0f GSDMD. YQHXP \uac1c\uc785 \ud6c4 \ub1cc \uc870\uc9c1\uc758 \uc5fc\uc99d\uc131 \uc0bc\ucd9c \ubc0f \ubd80\uc885\uc774 \ud06c\uac8c \uac10\uc18c\ud588\uc73c\uba70 \uc138\ud3ec \ud615\ud0dc \ubc0f \uc2e0\uacbd \uc561\ud3ec \ubcc0\uc131\uc774 \uac1c\uc120\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc694\uc57d\ud558\uba74, YQHXP\ub294 \ubc1c\uc5f4\uc99d\uc744 \uc5b5\uc81c\ud558\uc5ec \uae09\uc131 \ud5c8\ud608\uc131 \ub1cc\uc878\uc911 \uc950\uc758 \ub1cc \uc870\uc9c1 \uc5fc\uc99d\uc744 \uac10\uc18c\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib247\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib247\"><span class=\"anchor-text\">[247]<\/span><\/a>.<\/p>\n<\/section>\n<section id=\"sec0185\">\n<h4 id=\"sect0205\" class=\"u-margin-m-top u-margin-xs-bottom\">5.2.5. \uc158\ub098\uc624\ud478\uc704\uc548 \ub2ec\uc784(SNFYD)<\/h4>\n<p id=\"p0235\">SNFYD\ub294 \uc2e0\uc7a5\uacfc \ub1cc\uc758 \ub3d9\uc2dc\uce58\ub8cc \uc774\ub860\uc744 \ubc14\ud0d5\uc73c\ub85c \ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc5d0 \ud6a8\uacfc\uc801\uc778 \ucc98\ubc29\uc774\ub2e4. \uadf8 \uad6c\uc131\uc740 \ub2e4\uc74c\uacfc \uac19\uc2b5\ub2c8\ub2e4:\u00a0<em>\ud669\uae30 \uae30\uc218<\/em>\u00a030g<em>,\u00a0<\/em><em><a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c Rehmanniae\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/rehmannia\">\ub808\ud750\ub9c8\ub2c8\uc544\uc5d0<\/a><\/em><em>\u00a0\uae30\uc218 \ud504\ub77c\uc5d0\ud30c\ub77c\ud0c0<\/em>\u00a010g<em>, \ucf54\ub974\ub2c8 \ud504\ub7ed\ud22c\uc2a4<\/em>\u00a010g<em>, Dioscoreae Rhizoma<\/em>\u00a015g<em>, Rhodiolae Crenulatae Radix Et Rhizoma<\/em>\u00a020g<em>,\u00a0<\/em><em><a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c Moutan Cortex\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/moutan-cortex\">\ubb34\ud0c4\ud53c\uc9c8<\/a><\/em>\u00a010g<em>, \uc548\uc824\ub9ac\uce74\uc5d0 \uc2dc\ub128\uc2dc\uc2a4 \uae30\uc218<\/em>\u00a010g<em>, Paeoniae Radix Rubra<\/em>\u00a010g<em>,\u00a0<\/em><em><a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c Pheretima\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/pheretima\">\ud398\ub808\ud2f0\ub9c8<\/a><\/em>\u00a010g\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib248\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib248\"><span class=\"anchor-text\">[248]<\/span><\/a>. \uadf8\uac83\uc740 \ud608\uc561\uc744 \ud65c\uc131\ud654\ud558\uace0 \ub2f4\ubcf4\ub97c \uc900\uc124\ud558\ub294 \uac83\uacfc \uacb0\ud569\ub41c \ub9ce\uc740 \uae30 \ud65c\ub825, \uc815\uc561 \ubcf4\ucda9 \ubc0f \uc2e0\uc7a5 \ud65c\ub825 \uc57d\ud488\uacfc \uacb0\ud569\ub429\ub2c8\ub2e4. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 OGD \ubaa8\ub378\ub9c1 \ud6c4 PC12\uac00 \ud06c\uac8c \uc190\uc0c1\ub418\uc5c8\uc73c\uba70 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uacbd\ub85c\uc758 \ub2e4\uc591\ud55c \uc0ac\uc774\ud1a0\uce74\uc778\uc774 \ud06c\uac8c \uc99d\uac00\ud55c \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib249\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib249\"><span class=\"anchor-text\">[249]<\/span><\/a>. SNFYD \ud568\uc720 \ud608\uccad\uacfc INF39\uac00 \uc190\uc0c1\ub41c \ubd80\uc704\uc5d0 \uac1c\uc785\ud55c \ud6c4\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c PC12 \uc138\ud3ec\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/pc12-cell-line\">PC12 \uc138\ud3ec<\/a>PC12 \uc138\ud3ec\uc758 \ud615\ud0dc\uc640 \ud65c\uc131\uc774 \uac1c\uc120\ub418\uc5c8\uace0, \uc774\uc5d0 \ub530\ub77c NLRP3\/Caspase-1 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uacbd\ub85c\uc758 \ud65c\uc131\ud654\uac00 \uc57d\ud654\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc774\ub294 \uc774 \uacbd\ub85c\uc758 \uc5b5\uc81c\uac00 \uc138\ud3ec \uc0c1\ud0dc\uc758 \uac1c\uc120\uacfc \uad00\ub828\ub418\uc5b4 \uc788\uc73c\uba70 SNFYD\uc640 INF39 \ubaa8\ub450 \uc774 \uacbd\ub85c\uc758 \ud65c\uc131\ud654\ub97c \uc5b5\uc81c\ud560 \uc218 \uc788\uc74c\uc744 \ub098\ud0c0\ub0c5\ub2c8\ub2e4. SNFYD\ub294 NLRP3\/Caspase-1 \ubc0f \ud558\ub958 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uacbd\ub85c\ub97c \uc5b5\uc81c\ud568\uc73c\ub85c\uc368 \uc2e0\uacbd\uc138\ud3ec\uc758 \uc5fc\uc99d\uc131 \uc138\ud3ec\uc0ac\uba78\uc744 \uac10\uc18c\uc2dc\ucf1c \uc2e0\uacbd\uc870\uc9c1\uc744 \ubcf4\ud638\ud558\uace0 \ub1cc\uacbd\uc0c9 \uce58\ub8cc \ubaa9\uc801\uc744 \ub2ec\uc131\ud560 \uc218 \uc788\uc74c\uc744 \uc2dc\uc0ac\ud569\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib250\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib250\"><span class=\"anchor-text\">[250]<\/span><\/a>.<\/p>\n<\/section>\n<section id=\"sec0190\">\n<h4 id=\"sect0210\" class=\"u-margin-m-top u-margin-xs-bottom\">5.2.6. \uae30\ud0c0 \ucd94\ucd9c\ubb3c<\/h4>\n<p id=\"p0240\">\ub610\ud55c, \ucd5c\uadfc \uc5f0\uad6c\uc5d0\uc11c\ub294 \ud5e4\ud30c\ub9b0\uacfc \uac19\uc740 \ud56d\ud608\uc804\uc81c\uac00 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc5b5\uc81c\ud558\uc5ec \ud3d0 \uc190\uc0c1\uc744 \uac1c\uc120\ud560 \uc218 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, Yang et al. \ud5e4\ud30c\ub9b0\uc740 \ud328\ud608\uc99d\uc73c\ub85c \uc778\ud55c \ud3d0 \uc190\uc0c1\uc744 \uce58\ub8cc\ud560 \uc218 \uc788\ub294 \uc7a0\uc7ac\uc801\uc778 \ubc29\ubc95\uc77c \uc218 \uc788\ub294 hMGB1 LPS\ub85c \uc720\ubc1c\ub41c \uce74\uc2a4\ud30c\uc81c-11 \ud65c\uc131\ud654\ub97c \ucc28\ub2e8\ud558\uc5ec \ud3d0 \ub0b4\ud53c \uc138\ud3ec\uc758 \uc138\ud3ec\uc0ac\uba78\uc744 \uc5b5\uc81c\ud55c\ub2e4\ub294 \uc0ac\uc2e4\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib251\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib251\"><span class=\"anchor-text\">[251]<\/span><\/a>. Prathapanet al. \ubd80\ub4dc\ub7ec\uc6b4 \ucf54\ucf54\ub11b \ubb3c\uc5d0\ub294 \ud56d\uc0b0\ud654 \ubc0f \ud56d\ud608\uc804 \ud6a8\uacfc\uac00 \uc788\ub2e4\ub294 \uc0ac\uc2e4\uc774 \ubc1c\uacac\ub418\uc5c8\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc2e4\ud5d8\uc801 \uc2ec\uadfc\uacbd\uc0c9\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/experimental-myocardial-infarction\">\uc2e4\ud5d8\uc801 \uc2ec\uadfc\uacbd\uc0c9<\/a>\u00a0\ubaa8\ub378\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib252\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib252\"><span class=\"anchor-text\">[252]<\/span><\/a>, \uc5b4\ub9b0 \ucf54\ucf54\ub11b \uc8fc\uc2a4\ub294 \ub2e4\uc74c\uacfc \uad00\ub828\ub41c \uc77c\ubd80 \ubcd1\ub9ac \ud604\uc0c1\uc744 \ud06c\uac8c \uc904\uc77c \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc54c\uce20\ud558\uc774\uba38\ubcd1\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/alzheimer-disease\">\uc54c\uce20\ud558\uc774\uba38\ubcd1<\/a>\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib253\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib253\"><span class=\"anchor-text\">[253]<\/span><\/a>. \ucf54\ucf54\ub11b \uc6cc\ud130\ub294 \uc7a0\uc7ac\uc801\uc778 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uc5b5\uc81c\uc81c\uc77c \uc218 \uc788\uc73c\uba70 IS\uc5d0\uc11c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc870\uc808\ud558\ub294 \uc5ed\ud560\uc740 \ud5a5\ud6c4 \uc5f0\uad6c\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<p id=\"p0245\"><span class=\"small-caps\">\uc5d8<\/span>-\uc544\ub974\uae30\ub2cc\uc740 \uc720\uae30 \ud654\ud569\ubb3c\ub85c \uc874\uc7ac\ud569\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud504\ub85c\ud0c0\ubbfc\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/protamine\">\ud504\ub85c\ud0c0\ubbfc<\/a>\u00a0\ub300\ub7c9\uc73c\ub85c\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib254\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib254\"><span class=\"anchor-text\">[254]<\/span><\/a>. \ud569\uc131\uc758 \uc804\uc870\uc774\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc0b0\ud654\uc9c8\uc18c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/nitric-oxide\">\uc0b0\ud654\uc9c8\uc18c<\/a>\u00a0(NO)\ub294 \ud608\uad00\uc758 \uc628\uc804\ud55c \ub0b4\ud53c\ub97c \ubcf4\ud638\ud558\ub294 \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud608\uad00 \ud655\uc7a5\uc81c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/vasodilator-agent\">\ud608\uad00\ud655\uc7a5\uc81c<\/a>\u00a0\ubc0f \ub0b4\uc778\uc131 \ud56d\ub3d9\ub9e5\uacbd\ud654 \ubd84\uc790\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib254\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib254\"><span class=\"anchor-text\">[254]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib255\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib255\"><span class=\"anchor-text\">[255]<\/span><\/a>. \ub3d9\ubb3c \uc2e4\ud5d8\uc5d0\uc11c\ub294 \ub2e4\uc74c\uacfc \uac19\uc740 \uc0ac\uc2e4\uc744 \ubcf4\uc5ec\uc90d\ub2c8\ub2e4.\u00a0<span class=\"small-caps\">\uc5d8<\/span>-\uc544\ub974\uae30\ub2cc\uc5d0\ub294 \ubcf5\ud569\uccb4\uac00 \uc788\uc744 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \ud56d\uc751\uace0\uc81c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/anticoagulation\">\ud56d\uc751\uace0<\/a>, \ud56d\uc751\uace0 \ubc0f\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc12c\uc720\uc18c\ubd84\ud574\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/fibrinolysis\">\uc12c\uc720\uc18c\ubd84\ud574<\/a>\u00a0\ud6a8\uacfc\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib255\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib255\"><span class=\"anchor-text\">[255]<\/span><\/a>,\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib256\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib256\"><span class=\"anchor-text\">[256]<\/span><\/a>. \uace0\ud608\uc555 \uc950\uc5d0\uc11c Cylwik et al. \uadf8\uac83\uc744 \ubc1c\uacac\u00a0<span class=\"small-caps\">\uc5d8<\/span>-\uc544\ub974\uae30\ub2cc\uc740 \uc950\uc758 \ud608\uc555\uc744 \uac10\uc18c\uc2dc\ud0ac \uc218 \uc788\uc5c8\uace0, \uc7a5\uae30\uac04 \uce58\ub8cc\ub294 \uc720\uae00\ub85c\ubd88\ub9b0 \ud608\uc804 \uc6a9\ud574 \uc2dc\uac04\uacfc \ucd9c\ud608 \uc2dc\uac04\uc744 \ub2e8\ucd95\uc2dc\ud0a4\uace0 \ucf5c\ub77c\uac90 \uc720\ubc1c \ud608\uc18c\ud310 \uc751\uc9d1\uc744 \uc5b5\uc81c\ud588\uc2b5\ub2c8\ub2e4. \ub2e4\uc74c\uacfc \uac19\uc774 \uc81c\uc548\ub429\ub2c8\ub2e4.\u00a0<span class=\"small-caps\">\uc5d8<\/span>- \uc544\ub974\uae30\ub2cc\uc740 \uace0\ud608\uc555 \uc950 \ubaa8\ub378\uc5d0\uc11c \ud56d\ud608\uc804 \ud6a8\uacfc\ub97c \ub098\ud0c0\ub0c5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc815\ub9e5 \ud608\uc804\uc99d\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/phlebothrombosis\">\uc815\ub9e5 \ud608\uc804\uc99d<\/a>\u00a0\ubcf5\uc7a1\ud55c \ubc29\uc2dd\uc73c\ub85c\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib256\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib256\"><span class=\"anchor-text\">[256]<\/span><\/a>. \ucd5c\uadfc \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74\u00a0<span class=\"small-caps\">\uc5d8<\/span>-\uc544\ub974\uae30\ub2cc\uc740 \ubc1c\uc5f4\uc99d\uc758 \uc7a0\uc7ac\uc801\uc778 \uc5b5\uc81c\uc81c\uc77c \uc218 \uc788\uc2b5\ub2c8\ub2e4: Tanuseputero et al. \uc81c\uc548\ud588\ub2e4\u00a0<span class=\"small-caps\">\uc5d8<\/span>-\uc544\ub974\uae30\ub2cc\uc740 \ud328\ud608\uc99d \uc720\ubc1c\uc744 \uc644\ud654\ud558\uae30 \uc704\ud574 NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4\ub97c \ubd80\ubd84\uc801\uc73c\ub85c \uc5b5\uc81c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uae09\uc131 \uc2e0\uc7a5 \uc190\uc0c1\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/acute-kidney-injury\">\uae09\uc131 \uc2e0\uc7a5 \uc190\uc0c1<\/a>\u00a0\uc0dd\uc950\uc5d0\uc11c\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib257\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib257\"><span class=\"anchor-text\">[257]<\/span><\/a>. \ud608\uad00 \ud655\uc7a5, \ud56d\ud608\uc804 \ubc0f NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4 \ud65c\uc131 \uc5b5\uc81c\ub97c \uace0\ub824\ud558\uc5ec\u00a0<span class=\"small-caps\">\uc5d8<\/span>-\uc544\ub974\uae30\ub2cc\uc740 \ub2e4\uc74c\uacfc \uac19\uc774 \uad8c\uc7a5\ub429\ub2c8\ub2e4.\u00a0<span class=\"small-caps\">\uc5d8<\/span>-\uc544\ub974\uae30\ub2cc\uc740 \ud5c8\ud608\uc131 \ubd80\uc704\uc758 \ud608\ub958\ub97c \uc99d\uac00\uc2dc\ud0a4\uace0 IS\uc758 \ubc1c\uc5f4\uc99d\uc744 \uc5b5\uc81c\ud560 \uac00\ub2a5\uc131\uc774 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<div>\n<p id=\"p0250\">pyroptosis\ub97c \uc870\uc808\ud558\ub294 \ucc9c\uc5f0 \uc81c\ud488\uc758 \uc694\uc57d\uc740 \ub2e4\uc74c\uacfc \uac19\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#tbl0010\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"tbl0010\"><span class=\"anchor-text\">\ud45c 2<\/span><\/a>.<\/p>\n<div id=\"tbl0010\" class=\"tables colsep-0 rowsep-0 frame-topbot\">\n<p id=\"sp0025\"><span class=\"label\">\ud45c 2<\/span>. \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc870\uc808\ud558\ub294 \ucc9c\uc5f0 \ud654\ud569\ubb3c\uc758 \uc694\uc57d.<\/p>\n<div class=\"groups\">\n<table>\n<thead>\n<tr class=\"rowsep-1\">\n<th scope=\"col\">\ucc9c\uc5f0\uc81c\ud488<\/th>\n<th scope=\"col\">\ubaa8\ub378\/\uc9c8\ubcd1<\/th>\n<th scope=\"col\">\uc885<\/th>\n<th scope=\"col\">\ud6a8\uacfc<\/th>\n<th scope=\"col\">\ucc38\uc870<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<th scope=\"row\">\uac00\uc2a4\ud2b8\ub85c\ub518<\/th>\n<td>\uc911\ub300\ub1cc\ub3d9\ub9e5 \ud3d0\uc1c4\/\uc7ac\uad00\ub958(MCAO\/R), \uc0b0\uc18c-\ud3ec\ub3c4\ub2f9 \ubc15\ud0c8\/\uc7ac\uc0b0\uc18c\ud654(OGD\/R)<\/td>\n<td>Rattus norvegicus \ubc0f Rattus norvegicus\uc758 \uc6d0\ucd94 \ud53c\uc9c8 \ub274\ub7f0<\/td>\n<td>NLRP3, \uc5fc\uc99d \uc778\uc790(IL-1\u03b2, IL-18) \ubc0f \uc808\ub2e8\ub41c \uce74\uc2a4\ud30c\uc81c-1\uc744 \ud558\ud5a5 \uc870\uc808\ud558\uc5ec \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc5b5\uc81c\ud569\ub2c8\ub2e4. lncRNA NEAT1\/miR-22-3p \ucd95 \ubc0f lncRNA NEAT1\/miR-22-3p \ucd95\uc744 \uc870\uc808\ud569\ub2c8\ub2e4.<\/td>\n<td><a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib204\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib204\"><span class=\"anchor-text\">[204]<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\ud0c4\uc2dc\ub17c IIA<\/th>\n<td>OGD\/R<\/td>\n<td>BV2 \uc138\ud3ec(Mus musculus\uc758 \uc18c\uad50\uc138\ud3ec)<\/td>\n<td>NLRP3 \uc5fc\uc99d \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\uc5d0\uc11c IL-1\u03b2 \ubc0f IL-18\uc758 \ubc1c\ud604\uc744 \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4.<\/td>\n<td><a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib205\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib205\"><span class=\"anchor-text\">[205]<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\ub808\uc624\ub204\ub9b0<\/th>\n<td>MCAO<\/td>\n<td>Rattus norvegicus<\/td>\n<td>NLRP3\uc758 \ubc1c\ud604\uc744 \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4.<\/td>\n<td><a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib206\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib206\"><span class=\"anchor-text\">[206]<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\ud30c\uc624\ub2c8\ud50c\ub85c\ub9b0<\/th>\n<td>MCAO<\/td>\n<td>Rattus norvegicus<\/td>\n<td>NLRP3, Caspase-1 \ubc0f IL-1\u03b2 \uc218\uc900\uc744 \uc5b5\uc81c\ud569\ub2c8\ub2e4.<\/td>\n<td><a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib209\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib209\"><span class=\"anchor-text\">[209]<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\ubd80\ud2f8\ud504\ud0c8\ub77c\uc774\ub4dc<\/th>\n<td>MCAO<\/td>\n<td>Rattus norvegicus<\/td>\n<td>NLRP3 \uc778\ud50c\ub77c\ub9c8\uc19c \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c \uc870\uc808<\/td>\n<td><a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib210\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib210\"><span class=\"anchor-text\">[210]<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\ube0c\ub808\ube44\uc2a4\uce74\ud540<\/th>\n<td>MCAO\/R<\/td>\n<td>Rattus norvegicus<\/td>\n<td>CCI \uc950\uc758 \ud574\ub9c8\uc5d0\uc11c NLRP3 \uc5fc\uc99d \uc138\ud3ec\uc758 \ud65c\uc131\ud654\ub97c \uc5b5\uc81c\ud558\uace0 Caspase 1, IL-6 \ubc0f IL-1\u03b2 \ub2e8\ubc31\uc9c8\uc758 \ubc1c\ud604\uc744 \ud558\ud5a5 \uc870\uc808\ud558\uace0 Caspase-3 \ub2e8\ubc31\uc9c8\uc758 \ud65c\uc131\ud654\ub97c \uc5b5\uc81c\ud569\ub2c8\ub2e4.<\/td>\n<td><a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib211\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib211\"><span class=\"anchor-text\">[211]<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\ub808\uc2a4\ubca0\ub77c\ud2b8\ub864<\/th>\n<td>MCAO\/R<\/td>\n<td>Rattus norvegicus<\/td>\n<td>\uc18c\uad50\uc138\ud3ec NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4, Caspase-1 \ubc0f ZO-1\uc744 \uc870\uc808\ud569\ub2c8\ub2e4.<\/td>\n<td><a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib212\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib212\"><span class=\"anchor-text\">[212]<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\uc0b4\ube44\uc544\ub180\uc0b0<\/th>\n<td>MCAO\/R \ubc0f OGD\/R<\/td>\n<td>Rattus norvegicus\uc758 Rattus norvegicus \ubc0f \uc18c\uad50\uc138\ud3ec<\/td>\n<td>NLRP3 \uc778\ud50c\ub77c\ub9c8\uc19c\uc758 \ud65c\uc131\ud654\uc640 NLRP3 \uc778\ud50c\ub77c\ub9c8\uc19c\/\ubc1c\uc0b0\uc18c \uad00\ub828 \ub2e8\ubc31\uc9c8\uc758 \ubc1c\ud604\uc744 \uc5b5\uc81c\ud569\ub2c8\ub2e4.<\/td>\n<td><a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib213\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib213\"><span class=\"anchor-text\">[213]<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\ud788\ud53c\ub458\ub9b0<\/th>\n<td>MCAO<\/td>\n<td>Rattus norvegicus<\/td>\n<td>AMPK\/GSK3\u03b2 \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub97c \uc870\uc808\ud558\uc5ec NLRP3 \ub9e4\uac1c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc5b5\uc81c\ud569\ub2c8\ub2e4.<\/td>\n<td><a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib214\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib214\"><span class=\"anchor-text\">[214]<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\uc544\uc2a4\ud2b8\ub77c\uac08\ub85c\uc0ac\uc774\ub4dc IV<\/th>\n<td>MCAO\/R<\/td>\n<td>Rattus norvegicus<\/td>\n<td>NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4\uc758 \ud65c\uc131\ud654\ub97c \uc5b5\uc81c\ud569\ub2c8\ub2e4. \ub1cc \uc870\uc9c1\uc5d0\uc11c NLRP3, Caspase-1, pro-IL-1\u03b2, IL-1\u03b2, pro-IL-18 \ubc0f IL-18\uc758 \ub2e8\ubc31\uc9c8 \uc218\uc900\uc744 \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4. \uc778\uc0b0\ud654\ub41c NF-\u03baB \ub2e8\ubc31\uc9c8\uc758 \ubc1c\ud604\uc744 \uc5b5\uc81c\ud569\ub2c8\ub2e4.<\/td>\n<td><a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib223\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib223\"><span class=\"anchor-text\">[223]<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\ud30c\ub099\uc2a4 \uc0bc\uce60\uc778\uc0bc \uc0ac\ud3ec\ub2cc<\/th>\n<td>MCAO\/R<\/td>\n<td>Rattus norvegicus<\/td>\n<td>PINK1\/Parkin \uacbd\ub85c\ub97c \uc870\uc808\ud569\ub2c8\ub2e4. NLRP3 \uc778\ud50c\ub77c\ub9c8\uc19c\uc758 \ud65c\uc131\ud654\ub97c \uc5b5\uc81c\ud569\ub2c8\ub2e4.<\/td>\n<td><a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib232\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib232\"><span class=\"anchor-text\">[232]<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\ub3c4\ud64d\uc2dc\uc6b0\ud0d5<\/th>\n<td>MCAO<\/td>\n<td>Rattus norvegicus<\/td>\n<td>DRP1, NLRP3, Caspase-1 \ubc0f IL-1 \u03b2 \ub2e8\ubc31\uc9c8\uc758 \uc218\uc900\uc744 \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4.<\/td>\n<td><a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib233\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib233\"><span class=\"anchor-text\">[233]<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\ub3c4\ud64d\uc2dc\uc6b0\ud0d5<\/th>\n<td>MCAO\/R<\/td>\n<td>Rattus norvegicus<\/td>\n<td>HMGB1\/TLR4\/NF-kB \ubc0f MAPK \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub97c \uc5b5\uc81c\ud569\ub2c8\ub2e4.<\/td>\n<td><a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib234\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib234\"><span class=\"anchor-text\">[234]<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\ub098\uc624\uc2f1\uce6d \ucea1\uc290<\/th>\n<td>MCAO\/R<\/td>\n<td>Meriones unguiculatus<\/td>\n<td>ASC, NLRP3 \ubc0f Caspase-1 \ub2e8\ubc31\uc9c8\uc744 \ud558\ud5a5 \uc870\uc808\ud569\ub2c8\ub2e4. IL-18 \ubc0f IL-1\u03b2 \ud568\ub7c9\uc744 \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4.<\/td>\n<td><a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib239\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib239\"><span class=\"anchor-text\">[239]<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\ubd80\uc591\ud658\uc624\ud0d5<\/th>\n<td>MCAO\/R<\/td>\n<td>Rattus norvegicus<\/td>\n<td>NLRP3 \ub9e4\uac1c \ud45c\uc900 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uacbd\ub85c\uc758 NLRP3, ASC, pro-caspase-1, caspase-1 \ubc0f IL-1\u03b2 \ub2e8\ubc31\uc9c8\uc758 \ubc1c\ud604\uc744 \uc5b5\uc81c\ud569\ub2c8\ub2e4.<\/td>\n<td><a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib244\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib244\"><span class=\"anchor-text\">[244]<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\ub871\uc988 \ub2ec\uc784<\/th>\n<td>MCAO\/R<\/td>\n<td>Rattus norvegicus<\/td>\n<td>Caspase-1 \ubc0f IL-18 \ub2e8\ubc31\uc9c8\uc758 \ubc1c\ud604\uc744 \ud558\ud5a5 \uc870\uc808\ud569\ub2c8\ub2e4.<\/td>\n<td><a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib245\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib245\"><span class=\"anchor-text\">[245]<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">Yiqi Huoxue \ucc98\ubc29\uc804<\/th>\n<td>MCAO<\/td>\n<td>Rattus norvegicus<\/td>\n<td>IL-1\u03b2, TNF-\u03b1 \ubc0f IL-18\uc758 \uc218\uc900\uacfc P2RX7, Caspase-1, Caspase-11 \ubc0f GSDMD\uc758 \uc0c1\ub300\uc801 \ubc1c\ud604\uc744 \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4.<\/td>\n<td><a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib247\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib247\"><span class=\"anchor-text\">[247]<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\uc158\ub098\uc624\ud478\uc704\uc548 \ub2ec\uc784<\/th>\n<td>OGD<\/td>\n<td>Rattus norvegicus\uc758 PC12 \uc138\ud3ec<\/td>\n<td>NLRP3\/Caspase-1\uc744 \uc5b5\uc81c\ud569\ub2c8\ub2e4.<\/td>\n<td><a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bib250\" data-sd-ui-side-panel-opener=\"true\" data-xocs-content-type=\"reference\" data-xocs-content-id=\"bib250\"><span class=\"anchor-text\">[250]<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n<\/section>\n<\/section>\n<section id=\"sec0195\">\n<h2 id=\"sect0215\" class=\"u-h4 u-margin-l-top u-margin-xs-bottom\">6. \uc804\ub9dd<\/h2>\n<p id=\"p0255\">\uc6b0\ub9ac \uc5f0\uad6c\ud300\uc740 IS \uc774\ud6c4 \ud608\uad00 \uc2e0\uacbd \ub2e8\uc704\uc758 \ub2e4\uc591\ud55c \uc138\ud3ec \uadf8\ub8f9(\uc608: \ub274\ub7f0, \ubbf8\uc138\uc544\uad50\uc138\ud3ec, \uc131\uc0c1\uad50\uc138\ud3ec)\uc758 \ud504\ub85c\uadf8\ub7a8\ub41c \uc138\ud3ec \uc0ac\uba78 \ubaa8\ub4dc\ub97c \uc624\ub7ab\ub3d9\uc548 \uc5f0\uad6c\ud574 \uc654\uc2b5\ub2c8\ub2e4. \ub2e4\ub978 \uc5f0\uad6c \ubcf4\uace0\uc11c\uc640 \uacb0\ud569\ud558\uc5ec \uc6b0\ub9ac\ub294 IS \uc774\ud6c4\uc5d0 apoptosis, ferroptosis \ubc0f autophagy\uc640 \uac19\uc740 \ub2e4\uc591\ud55c \uc138\ud3ec \uc0ac\uba78 \ubaa8\ub4dc\uac00 \ubc1c\uc0dd\ud588\uc73c\uba70 apoptosis\uc640 pyroptosis\uc758 \ud615\ud0dc\uac00 \ud2b9\uc815 \uc720\uc0ac\uc810\uc744 \uac00\uc9c0\uace0 \uc788\uc74c\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc2e0\uacbd\uc5fc\uc99d\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/neuroinflammation\">\uc2e0\uacbd\uc5fc\uc99d<\/a>\u00a0IS \ub2e4\uc74c\uc740 \ub1cc\uc190\uc0c1\uc73c\ub85c \uc774\uc5b4\uc9c0\ub294 \uac00\uc7a5 \uc911\uc694\ud55c \ubcd1\ub9ac\ud559\uc801 \uacfc\uc815\uc774\uba70, \uc5ec\uae30\uc11c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub294 \uc2e0\uacbd\uc5fc\uc99d\uc758 \uc911\uc694\ud55c \ubd80\ubd84\uc785\ub2c8\ub2e4. \uc774\ub294 \ub1cc\ud5c8\ud608 \ud6c4 \uc2e0\uacbd\uc5fc\uc99d \uad00\ub828 \ud504\ub85c\uadf8\ub7a8\ud654\ub41c \uc138\ud3ec \uc0ac\uba78\uc5d0 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uac00 \ube44\uc815\uc0c1\uc801\uc73c\ub85c \uc911\uc694\ud558\ub2e4\ub294 \uac83\uc744 \uc2dc\uc0ac\ud569\ub2c8\ub2e4. \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc5d0 \uc758\ud574 \uc720\ubc1c\ub418\ub294 \uad00\ub828 \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub294 \ub2e4\ub978 \ud504\ub85c\uadf8\ub7a8\ub41c \uc138\ud3ec \uc0ac\uba78 \uacbd\ub85c\uc640\ub3c4 \uad50\ucc28\ud558\uba70, \uc774\ub294 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \ud45c\uc801\uc73c\ub85c \ud558\ub294 \uc57d\ubb3c \uac1c\ubc1c\uc774 IS\ub97c \uce58\ub8cc\ud558\ub294 \uc911\uc694\ud55c \ubc29\ubc95\uc784\uc744 \uc2dc\uc0ac\ud569\ub2c8\ub2e4.<\/p>\n<p id=\"p0260\">\ud604\uc7ac \uc5f0\uad6c\uc5d0\ub294 \uc5ec\uc804\ud788 \uac1c\uc120\uc774 \ud544\uc694\ud55c \uc601\uc5ed\uc774 \uc788\uc2b5\ub2c8\ub2e4. (1) \ud604\uc7ac \uc5f0\uad6c\uc758 \ub3d9\ubb3c \ubaa8\ub378\uc5d0\uc11c \uc815\uc0c1\ud654 \ubc0f \ud1b5\uc77c \ubb38\uc81c\ub85c \uc778\ud574 \ub2e4\uc591\ud55c \uc138\ud3ec\uc758 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc5d0 \ub300\ud55c \uacb0\ub860\uc774 \ub0b4\ub824\uc84c\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc2e0\uacbd\uacc4\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/nervous-system\">\uc2e0\uacbd\uacc4<\/a>\u00a0\uc77c\uad00\uc131\uc774 \uc5c6\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c \ud5a5\ud6c4 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc5d0 \ub300\ud55c \uc5f0\uad6c\uc5d0\uc11c\ub294 \ud5c8\ud608\uc131 \ub1cc\uc878\uc911 \ub3d9\ubb3c \ubaa8\ub378\uc5d0\uc11c \ubcf4\ub2e4 \ud45c\uc900\ud654\ub418\uace0 \ud1b5\uc77c\ub41c \uc548\uc815\uc801\uc778 \ubaa8\ub378\uc774 \ud544\uc694\ud558\uba70, \uc774\ub294 \ub610\ud55c \ud56d\ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uc57d\ubb3c\uc758 \uc2e4\uc81c \ud6a8\uacfc\ub97c \uacb0\uc815\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. (2) \ud5a5\ud6c4 \uc5f0\uad6c\ub97c \ud1b5\ud574 \ucc9c\uc5f0 \ud654\ud569\ubb3c\uc758 \uc7a5\uae30\uc801\uc778 \ub1cc \ubcf4\ud638 \ud6a8\uacfc\uc640 \ub2e4\uc591\ud55c \uc124\uce58\ub958 \ubc0f \ub300\ud615 \ud3ec\uc720\ub958 \ub1cc\uc878\uc911 \ubaa8\ub378\uc5d0\uc11c \ubc1c\uc5f4\uc99d\uc744 \uc870\uc808\ud558\ub294 \uba54\ucee4\ub2c8\uc998\uc744 \ud655\uc778\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc55e\uc73c\ub85c\ub294 \ub354 \ub9ce\uc740 \uad00\uc2ec\uc744 \uae30\uc6b8\uc5ec\uc57c \ud560 \uac83\uc785\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc57d\ub3d9\ud559\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/pharmacokinetics\">\uc57d\ub3d9\ud559<\/a>,\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc57d\ub825\ud559\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/pharmacodynamics\">\uc57d\ub825\ud559<\/a>, \ud604\uc7ac \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc870\uc808\ud558\ub294 \ucc9c\uc5f0 \ud654\ud569\ubb3c\uc758 \ub3c5\uc131\ud559\uc801 \ud2b9\uc131. (3) \ub610\ud55c, \ub1cc\ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc5d0\uc11c \ubc1c\uc5f4\uc99d \uc870\uc808\uc5d0 \uc788\uc5b4\uc11c \ucc9c\uc5f0 \ud654\ud569\ubb3c\uc758 \uc870\ud569\uc758 \uc2dc\ub108\uc9c0 \ud6a8\uacfc\uc640 \uc2e0\uacbd\uc5fc\uc99d\uc744 \uc5b5\uc81c\ud558\ub294 \uc2e0\uacbd\ubcf4\ud638 \ud6a8\uacfc\uc5d0 \ub300\ud55c \ud5a5\ud6c4 \uc5f0\uad6c\uac00 \ud544\uc694\ud558\ub2e4. (4) \ubaa8\ub4e0 \uacb0\uacfc\uac00 \uae0d\uc815\uc801\uc774\uba74 \ub2e4\uc74c \ub2e8\uacc4\ub294 \ub2e4\uc74c\uc744 \uc218\ud589\ud558\ub294 \uac83\uc785\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc784\uc0c1 \uc2dc\ud5d8\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/clinical-trial\">\uc784\uc0c1 \uc2dc\ud5d8<\/a>\u00a0\uc7a0\uc7ac\ub825\uc758\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc2dd\ubb3c\ud654\ud559\ubb3c\uc9c8\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/phytochemical\">\uc2dd\ubb3c\ud654\ud559\ubb3c\uc9c8<\/a>\u00a0\ub1cc \ud5c8\ud608\/\ub1cc\uc878\uc911\uc5d0 \ub300\ud55c \uc2e0\uacbd \ubcf4\ud638 \ud6a8\uacfc\ub97c \uc870\uc0ac\ud558\uae30 \uc704\ud574(\uc608\ub97c \ub4e4\uc5b4, \ud300\uc740 \ud604\uc7ac \ub1cc \uc18c\ud608\uad00 \uc9c8\ud658 \uce58\ub8cc\uc5d0 Naotai Fang\uc758 \uc784\uc0c1 \uc2dc\ud5d8\uc744 \uc218\ud589\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4: ChiCTR1900024524).<\/p>\n<\/section>\n<section id=\"sec0200\">\n<h2 id=\"sect0220\" class=\"u-h4 u-margin-l-top u-margin-xs-bottom\">7. \uc694\uc57d<\/h2>\n<p id=\"p0265\">\uc804 \uc5fc\uc99d\uc131 \ud504\ub85c\uadf8\ub7a8 \uc138\ud3ec \uc0ac\uba78\uc778 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub294 \uc8fc\ub85c Caspase-1\uc5d0 \uc758\ud574 \ub9e4\uac1c\ub418\ub294 \uace0\uc804\uc801\uc778 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uacbd\ub85c\ub97c \ud1b5\ud574 \uc138\ud3ec \uc0ac\uba78\uacfc \uc2e0\uacbd\uc5fc\uc99d\uc744 \uc720\ub3c4\ud568\uc73c\ub85c\uc368 \ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc758 \ubcd1\ub9ac\ud559\uc801 \uacfc\uc815\uc5d0\uc11c \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \ube44\ud45c\uc900 pyroptotic \uacbd\ub85c\uc640 IS \uc0ac\uc774\uc758 \uad00\uacc4\ub294 \uc544\uc9c1 \ubc1d\ud600\uc9c0\uc9c0 \uc54a\uc558\uc2b5\ub2c8\ub2e4. pyroptosis\uc5d0 \ub300\ud55c \ub2e4\ub978 \uba54\ucee4\ub2c8\uc998\uc740 \ud5a5\ud6c4 \ucd94\uac00 \uc5f0\uad6c\uac00 \ud544\uc694\ud569\ub2c8\ub2e4. \ud604\uc7ac \uc5f0\uad6c \uacb0\uacfc\uc5d0 \ub530\ub974\uba74\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc57d\ubb3c \ud0c0\uac9f\ud305\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/drug-delivery-system\">\uc57d\ubb3c \ud0c0\uac9f\ud305<\/a>\u00a0\ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uacbd\ub85c\uc758 \uc8fc\uc694 \ub2e8\ubc31\uc9c8\uc740 \ud5c8\ud608\uc131 \ub1cc \uc190\uc0c1\uc744 \uc5b4\ub290 \uc815\ub3c4 \uc644\ud654\ud560 \uc218 \uc788\uc9c0\ub9cc, \uc774\ub4e4\uc758 \uc5f0\uad6c\ub294 \uc8fc\ub85c \uc138\ud3ec \ubc0f \ub3d9\ubb3c \uc2e4\ud5d8\uc5d0 \uad6d\ud55c\ub418\uc5b4 \uc788\uc73c\uba70, \ubd80\uc871\ud55c \ubd80\ubd84\uc774 \uc788\uc2b5\ub2c8\ub2e4.\u00a0<a class=\"topic-link\" title=\"ScienceDirect\uc758 AI \uc0dd\uc131 \uc8fc\uc81c \ud398\uc774\uc9c0\uc5d0\uc11c \uc784\uc0c1 \uc5f0\uad6c\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.\" href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/clinical-research\">\uc784\uc0c1 \uc5f0\uad6c<\/a>\u00a0\uc99d\uac70. \ub530\ub77c\uc11c IS\uc5d0\uc11c \ubc1c\uc5f4\uc99d\uc758 \uc870\uc808 \uba54\ucee4\ub2c8\uc998\uc744 \ud0d0\uad6c\ud558\uae30 \uc704\ud55c \ucd94\uac00 \uc784\uc0c1 \uc5f0\uad6c\ub294 \ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc758 \uc608\ubc29 \ubc0f \uce58\ub8cc\ub97c \uc704\ud55c \uc0c8\ub85c\uc6b4 \uce58\ub8cc \uc804\ub7b5\uacfc \uc774\ub860\uc801 \uae30\ucd08\ub97c \uc81c\uacf5\ud560 \uac83\uc73c\ub85c \uae30\ub300\ub429\ub2c8\ub2e4. \ucc9c\uc5f0 \ud654\ud569\ubb3c\uc5d0 \uc758\ud55c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uc870\uc808\uacfc \uad00\ub828\ud558\uc5ec, \uc6b0\ub9ac\uc758 \uc77c\ubc18\ud654\ub97c \ud1b5\ud574 \ucc9c\uc5f0 \uc2dd\ubb3c \ud654\ud569\ubb3c\uc774 \ub2e8\uc77c \uc131\ubd84\ubfd0\ub9cc \uc544\ub2c8\ub77c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc870\uc808\ud568\uc73c\ub85c\uc368 \ub1cc \ud5c8\ud608\uc744 \uc870\uc808\ud560 \uc218 \uc788\uc74c\uc744 \uc54c \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub2e4\uc131\ubd84 \ucc9c\uc5f0 \uc2dd\ubb3c \ud654\ud569\ubb3c\uc740 \ub610\ud55c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc5d0 \uc758\ud574 \uc720\ubc1c\ub418\ub294 \uc5fc\uc99d \uc5f0\uc1c4\ubc18\uc751\uc744 \uc870\uc808\ud558\ub294 \ub370 \uc7a0\uc7ac\uc801\uc778 \uc2dc\ub108\uc9c0 \ud6a8\uacfc\ub97c \ub098\ud0c0\ub0b4\ub294 \uac83\uc73c\ub85c \ubcfc \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub294 \ubbf8\ub798\uc5d0 \ub2e4\uc591\ud55c \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub85c \uc778\ud574 \ubc1c\uc0dd\ud558\ub294 \ubc1c\uc5f4\uc99d \ub9e4\uac1c \uc2e0\uacbd\uc5fc\uc99d\uc5d0 \ub300\ud55c \ub2e4\uc591\ud55c \ucc9c\uc5f0 \ud654\ud569\ubb3c\uc758 \uaddc\uc81c \ud6a8\uacfc\ub97c \uc5f0\uad6c\ud558\ub3c4\ub85d \uc601\uac10\uc744 \uc90d\ub2c8\ub2e4.<\/p>\n<\/section>\n<section id=\"sec0205\">\n<h2 id=\"sect0225\" class=\"u-h4 u-margin-l-top u-margin-xs-bottom\">CRediT \uc800\uc790 \uae30\uc5ec \uc120\uc5b8\ubb38<\/h2>\n<p id=\"p0270\"><strong>\uc591 \uce74\uc774\ub9b0:<\/strong>\u00a0\uac1c\ub150\ud654, \ubc29\ubc95\ub860, \ud615\uc2dd\uc801 \ubd84\uc11d, \uc870\uc0ac, \uc9d1\ud544 \u2013 \uc6d0\ubcf8 \ucd08\uc548;\u00a0<strong>\uc831 \ub958\ud305:<\/strong>\u00a0\uac1c\ub150\ud654, \ubc29\ubc95\ub860, \uc18c\ud504\ud2b8\uc6e8\uc5b4, \ud615\uc2dd\uc801 \ubd84\uc11d, \uc870\uc0ac, \uae00\uc4f0\uae30 \u2013 \uc6d0\ubcf8 \ucd08\uc548;\u00a0<strong>\uc9c4\uc1a1 \uc831:<\/strong>\u00a0\ubc29\ubc95\ub860, \uacf5\uc2dd \ubd84\uc11d, \uc870\uc0ac;\u00a0<strong>\ud305\ud305 \ubc14\uc624:<\/strong>\u00a0\ubc29\ubc95\ub860, \ud615\uc2dd\uc801 \ubd84\uc11d, \uc870\uc0ac, \uc9d1\ud544 \u2013 \uc6d0\ubcf8 \ucd08\uc548;\u00a0<strong>\uc0e4\uc624\uc704\uc548:<\/strong>\u00a0\ubc29\ubc95\ub860, \uacf5\uc2dd \ubd84\uc11d, \uc870\uc0ac;\u00a0<strong>\uc655 \uc0b0\uc0e8:<\/strong>\u00a0\ubc29\ubc95\ub860, \uacf5\uc2dd \ubd84\uc11d, \uc870\uc0ac;\u00a0<strong>\uc655\uc0f9:<\/strong>\u00a0\ubc29\ubc95\ub860, \uacf5\uc2dd \ubd84\uc11d, \uc870\uc0ac;\u00a0<strong>\ud558\uc624 \uc26c:<\/strong>\u00a0\ubc29\ubc95\ub860, \uacf5\uc2dd \ubd84\uc11d, \uc870\uc0ac;\u00a0<strong>\uc9c4\uc6ec \uac8c:<\/strong>\u00a0\uac1c\ub150\ud654, \ubc29\ubc95\ub860, \ud615\uc2dd\uc801 \ubd84\uc11d, \uc870\uc0ac, \uc9d1\ud544 \u2013 \uac80\ud1a0 \ubc0f \ud3b8\uc9d1.<\/p>\n<\/section>\n<\/div>\n<section id=\"coi0005\">\n<h2 id=\"sect0230\" class=\"u-h4 u-margin-l-top u-margin-xs-bottom\">\uc774\ud574 \uc0c1\ucda9 \uc9c4\uc220\uc11c<\/h2>\n<p id=\"p0275\">\uc800\uc790\ub294 \uc774 \ubb38\uc11c\uc5d0 \ubcf4\uace0\ub41c \uc791\uc5c5\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\ub294 \uacbd\uc7c1\uc801\uc778 \uae08\uc804\uc801 \uc774\ud574\uad00\uacc4\ub098 \uac1c\uc778\uc801\uc778 \uad00\uacc4\uac00 \uc5c6\ub2e4\uace0 \uc120\uc5b8\ud569\ub2c8\ub2e4.<\/p>\n<\/section>\n<section id=\"ack0005\">\n<h2 id=\"sect0235\" class=\"u-h4 u-margin-l-top u-margin-xs-bottom\">\uac10\uc0ac\uc758 \ub9d0<\/h2>\n<p id=\"p0280\">\uc774 \uc791\ud488\uc740 \uc5d0\uc11c \uc9c0\uc6d0\uc744 \ubc1b\uc2b5\ub2c8\ub2e4.\u00a0<span id=\"gs1\">\uc911\uad6d \uad6d\ub9bd\uc790\uc5f0\uacfc\ud559\uc7ac\ub2e8<\/span>\u00a0(<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#gs1\"><span class=\"anchor-text\">81774174<\/span><\/a>),\u00a0<span id=\"gs2\">\uc911\uad6d \uad6d\uac00\uc911\uc810 \uc5f0\uad6c\uac1c\ubc1c \ud504\ub85c\uc81d\ud2b8<\/span>\u00a0(\uc544\ub2c8\uc694.\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#gs2\"><span class=\"anchor-text\">2018YFC1704904<\/span><\/a>),\u00a0<span id=\"gs3\">\ud6c4\ub09c\uc131 \uad6d\ub9bd\uc790\uc5f0\uacfc\ud559\uc7ac\ub2e8<\/span>, \uc911\uad6d (<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#gs3\"><span class=\"anchor-text\">2020JJ5424<\/span><\/a>\u00a0\uadf8\ub9ac\uace0\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#gs3\"><span class=\"anchor-text\">2020JJ5442<\/span><\/a>),\u00a0<span id=\"gs4\">\ud6c4\ub09c\uc911\uc758\uacfc\ub300\ud559\uad50 \ud55c\uc758\ud559\uacfc \uc11c\uc591\uc758\ud559\uc744 \ud1b5\ud569\ud55c \u201c\uc774\uc911 \uc77c\ub958\u201d \ud559\ubb38 \uacf5\uac1c \uae30\uae08 \ud504\ub85c\uc81d\ud2b8<\/span>\u00a0(<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#gs4\"><span class=\"anchor-text\">2020ZXYJH08<\/span><\/a>\u00a0\uadf8\ub9ac\uace0\u00a0<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#gs4\"><span class=\"anchor-text\">2020ZXYJH09<\/span><\/a>),\u00a0<span id=\"gs5\">\ud6c4\ub09c\uc131 \uad50\uc721\ubd80 \uccad\uc18c\ub144 \uae30\uae08 \ud504\ub85c\uc81d\ud2b8<\/span>\u00a0(<a class=\"anchor u-display-inline anchor-paragraph\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#gs5\"><span class=\"anchor-text\">21B0386<\/span><\/a>).<\/p>\n<\/section>\n<\/div>\n<div class=\"text-content u-font-serif\">\n<section id=\"da0005\">\n<h2 id=\"sect0020\" class=\"u-h4 u-margin-l-top u-margin-xs-bottom\">\ub370\uc774\ud130 \ubc0f \uc790\ub8cc\uc758 \uac00\uc6a9\uc131<\/h2>\n<p id=\"p0020\">\uc774 \uc5f0\uad6c \uacb0\uacfc\ub97c \ub4b7\ubc1b\uce68\ud558\ub294 \ub370 \uc0ac\uc6a9\ub41c \ub370\uc774\ud130\ub294 \uae30\uc0ac\uc5d0 \ud3ec\ud568\ub418\uc5b4 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/section>\n<\/div>\n<div class=\"Tail text-s\"><\/div>\n<section id=\"bibliog0005\" class=\"bibliography u-font-serif text-s\">\n<h2 class=\"section-title u-h4 u-margin-l-top u-margin-xs-bottom\">\ucc38\uace0\uc790\ub8cc<\/h2>\n<section id=\"bb0005\" class=\"bibliography-sec\">\n<ol id=\"reference-links-bb0005\" class=\"references\">\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib1\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib1\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[1]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">LE \uc5d0\ubc18\uc2a4, JL \ud14c\uc77c\ub7ec, CJ \uc2a4\ubbf8\uc2a4, HAT \ud504\ub9ac\ucc28\ub4dc, AS \uadf8\ub9b0\uc2a4\ud0c0\uc778, SM \uc568\ub7f0<\/div>\n<div id=\"ref-id-sbref1\" class=\"title text-m\">\uc2ec\ud608\uad00 \ub3d9\ubc18\uc9c8\ud658, \uc5fc\uc99d, \ub1cc\uc18c\ud608\uad00\uc9c8\ud658<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Cardiovasc Res., 117 (13) (2021), pp. 2575-2588,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1093\/cvr\/cvab284\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1093\/cvr\/cvab284<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85121137397&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref1\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Cardiovascular%20comorbidities%2C%20inflammation%2C%20and%20cerebral%20small%20vessel%20disease&amp;publication_year=2021&amp;author=L.E.%20Evans&amp;author=J.L.%20Taylor&amp;author=C.J.%20Smith&amp;author=H.A.T.%20Pritchard&amp;author=A.S.%20Greenstein&amp;author=S.M.%20Allan\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref1\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib2\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib2\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[2]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">P. Han, W. Zhang, L. Kang, Y. Ma, L. Fu, L. Jia, H. Yu, X. Chen, L. Hou, L. Wang, X. Yu, M. Kohzuki, Q. \uad88<\/div>\n<div id=\"ref-id-sbref2\" class=\"title text-m\">\ub1cc\uc878\uc911\uc5d0 \ub300\ud55c \uc6b4\ub3d9\uc758 \uc774\uc810\uc5d0 \ub300\ud55c \uc784\uc0c1\uc801 \uc99d\uac70<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uace0\uae09 \ud2b9\uae09. \uba54\ub4dc. Biol., 1000(2017), pp. 131-151,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1007\/978-981-10-4304-8_9\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1007\/978-981-10-4304-8_9<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85032976954&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref2\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Clinical%20Evidence%20of%20Exercise%20Benefits%20for%20Stroke&amp;publication_year=2017&amp;author=P.%20Han&amp;author=W.%20Zhang&amp;author=L.%20Kang&amp;author=Y.%20Ma&amp;author=L.%20Fu&amp;author=L.%20Jia&amp;author=H.%20Yu&amp;author=X.%20Chen&amp;author=L.%20Hou&amp;author=L.%20Wang&amp;author=X.%20Yu&amp;author=M.%20Kohzuki&amp;author=Q.%20Guo\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref2\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib3\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib3\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[3]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">VL Feigin, M. Brainin, B. Norrving, S. Martins, RL Sacco, W. Hacke, M. Fisher, J. Pandian, P. Lindsay<\/div>\n<div id=\"ref-id-sbref3\" class=\"title text-m\">\uc138\uacc4\ub1cc\uc878\uc911\uae30\uad6c(WSO): 2022\ub144 \uae00\ub85c\ubc8c \ub1cc\uc878\uc911 \uc0ac\uc2e4 \uc790\ub8cc<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uad6d\uc81c J. \ub1cc\uc878\uc911, 17(1)(2022), 18-29\ud398\uc774\uc9c0,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1177\/17474930211065917\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1177\/17474930211065917<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85122375323&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref3\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=World%20Stroke%20Organization%20%3A%20Global%20Stroke%20Fact%20Sheet%202022&amp;publication_year=2022&amp;author=V.L.%20Feigin&amp;author=M.%20Brainin&amp;author=B.%20Norrving&amp;author=S.%20Martins&amp;author=R.L.%20Sacco&amp;author=W.%20Hacke&amp;author=M.%20Fisher&amp;author=J.%20Pandian&amp;author=P.%20Lindsay\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref3\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib4\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib4\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[4]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">PB Sporns, HJ Fullerton, S. Lee, H. Kim, WD Lo, MT Mackay, M. Wildgruber<\/div>\n<div id=\"ref-id-sbref4\" class=\"title text-m\">\uc5b4\ub9b0 \uc2dc\uc808\uc758 \ub1cc\uc878\uc911<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Nat. \ubaa9\uc0ac Dis. Prim., 8(1)(2022), p. 12,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1038\/s41572-022-00337-x\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1038\/s41572-022-00337-x<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85125345650&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref4\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Childhood%20stroke&amp;publication_year=2022&amp;author=P.B.%20Sporns&amp;author=H.J.%20Fullerton&amp;author=S.%20Lee&amp;author=H.%20Kim&amp;author=W.D.%20Lo&amp;author=M.T.%20Mackay&amp;author=M.%20Wildgruber\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref4\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib5\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib5\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[5]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">MY Wu, GT Yiang, WT Liao, AP Tsai, YL Cheng, PW Cheng, CY Li, CJ Li<\/div>\n<div id=\"ref-id-sbref5\" class=\"title text-m\">\ud5c8\ud608 \ubc0f \uc7ac\uad00\ub958 \uc190\uc0c1\uc758 \ud604\uc7ac \uba54\ucee4\ub2c8\uc998 \uac1c\ub150<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Cell PhysiolBiochem, 46 (4) (2018), pp. 1650-1667,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1159\/000489241\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1159\/000489241<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85046014150&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref5\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Current%20mechanistic%20concepts%20in%20ischemia%20and%20reperfusion%20injury&amp;publication_year=2018&amp;author=M.Y.%20Wu&amp;author=G.T.%20Yiang&amp;author=W.T.%20Liao&amp;author=A.P.%20Tsai&amp;author=Y.L.%20Cheng&amp;author=P.W.%20Cheng&amp;author=C.Y.%20Li&amp;author=C.J.%20Li\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref5\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib6\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib6\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[6]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">K. \ud4e8\ub9ac<\/div>\n<div id=\"ref-id-sbref6\" class=\"title text-m\">\ub1cc\uc878\uc911\uc758 \uc5ed\ud559 \ubc0f \uc77c\ucc28 \uc608\ubc29<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uacc4\uc18d. (Minne), 26(2)(2020), pp. 260-267,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1212\/CON.0000000000000831\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1212\/CON.0000000000000831<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85082634848&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref6\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Epidemiology%20and%20primary%20prevention%20of%20stroke&amp;publication_year=2020&amp;author=K.%20Furie\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref6\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib7\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib7\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[7]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">MS Ekker, EM Boot, AB Singhal, KS Tan, S. Debette, AM Tuladhar, FE de Leeuw<\/div>\n<div id=\"ref-id-sbref7\" class=\"title text-m\">\uc80a\uc740 \uc131\uc778\uc758 \ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc758 \uc5ed\ud559, \ubcd1\uc778\ud559 \ubc0f \uad00\ub9ac<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Lancet Neurol., 17 (9) (2018), pp. 790-801,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/S1474-4422(18)30233-3\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/S1474-4422(18)30233-3<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1474442218302333\/pdfft?md5=477909fe66f856d9a85dc0241c093220&amp;pid=1-s2.0-S1474442218302333-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref7\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1474442218302333\" aria-describedby=\"ref-id-sbref7\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85051392583&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref7\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Epidemiology%2C%20aetiology%2C%20and%20management%20of%20ischaemic%20stroke%20in%20young%20adults&amp;publication_year=2018&amp;author=M.S.%20Ekker&amp;author=E.M.%20Boot&amp;author=A.B.%20Singhal&amp;author=K.S.%20Tan&amp;author=S.%20Debette&amp;author=A.M.%20Tuladhar&amp;author=F.E.%20de%20Leeuw\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref7\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib8\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib8\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[8]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">S. Wu, B. Wu, M. Liu, Z. Chen, W. Wang, CS Anderson, P. Sandercock, Y. Wang, Y. Huang, L. Cui, C. Pu, J. Jia, T. Zhang , X. Liu, S. Zhang, P. Xie, D. Fan, X. Ji, KL Wong, L. Wang<\/div>\n<div id=\"ref-id-sbref8\" class=\"title text-m\">\uc911\uad6d \ub1cc\uc878\uc911 \uc5f0\uad6c \ud611\ub825. \uc911\uad6d\uc758 \ub1cc\uc878\uc911: \uc5ed\ud559, \uc608\ubc29 \ubc0f \uad00\ub9ac \ubd84\uc57c\uc758 \ubc1c\uc804\uacfc \uacfc\uc81c<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Lancet Neurol., 18 (4) (2019), pp. 394-405,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/S1474-4422(18)30500-3\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/S1474-4422(18)30500-3<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1474442218305003\/pdfft?md5=ddbfdb704b02c545afc4c110452fd724&amp;pid=1-s2.0-S1474442218305003-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref8\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1474442218305003\" aria-describedby=\"ref-id-sbref8\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85062907971&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref8\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=China%20Stroke%20Study%20Collaboration.%20Stroke%20in%20China%3A%20advances%20and%20challenges%20in%20epidemiology%2C%20prevention%2C%20and%20management&amp;publication_year=2019&amp;author=S.%20Wu&amp;author=B.%20Wu&amp;author=M.%20Liu&amp;author=Z.%20Chen&amp;author=W.%20Wang&amp;author=C.S.%20Anderson&amp;author=P.%20Sandercock&amp;author=Y.%20Wang&amp;author=Y.%20Huang&amp;author=L.%20Cui&amp;author=C.%20Pu&amp;author=J.%20Jia&amp;author=T.%20Zhang&amp;author=X.%20Liu&amp;author=S.%20Zhang&amp;author=P.%20Xie&amp;author=D.%20Fan&amp;author=X.%20Ji&amp;author=K.L.%20Wong&amp;author=L.%20Wang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref8\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib9\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib9\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[9]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">HF Yan, QZ Tuo, QZ Yin, P. Lei<\/div>\n<div id=\"ref-id-sbref9\" class=\"title text-m\">\ud5c8\ud608\/\uc7ac\uad00\ub958 \uad00\ub828 \uc190\uc0c1\uc5d0\uc11c \ud398\ub86d\ud1a0\uc2dc\uc2a4\uc758 \ubcd1\ub9ac\ud559\uc801 \uc5ed\ud560<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ub3d9\ubb3c\uc6d0. \uacb0\uc758\uc548, 41 (3) (2020), pp. 220-230,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.24272\/j.issn.2095-8137.2020.042\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.24272\/j.issn.2095-8137.2020.042<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85084692954&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref9\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20pathological%20role%20of%20ferroptosis%20in%20ischemiareperfusion-related%20injury&amp;publication_year=2020&amp;author=H.F.%20Yan&amp;author=Q.Z.%20Tuo&amp;author=Q.Z.%20Yin&amp;author=P.%20Lei\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref9\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib10\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib10\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[10]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">MY Wu, GT Yiang, WT Liao, AP Tsai, YL Cheng, PW Cheng, CY Li, CJ Li<\/div>\n<div id=\"ref-id-sbref10\" class=\"title text-m\">\ud5c8\ud608 \ubc0f \uc7ac\uad00\ub958 \uc190\uc0c1\uc758 \ud604\uc7ac \uba54\ucee4\ub2c8\uc998 \uac1c\ub150<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Cell PhysiolBiochem, 46 (4) (2018), pp. 1650-1667,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1159\/000489241\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1159\/000489241<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85046014150&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref10\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Current%20Mechanistic%20Concepts%20in%20Ischemia%20and%20Reperfusion%20Injury&amp;publication_year=2018&amp;author=M.Y.%20Wu&amp;author=G.T.%20Yiang&amp;author=W.T.%20Liao&amp;author=A.P.%20Tsai&amp;author=Y.L.%20Cheng&amp;author=P.W.%20Cheng&amp;author=C.Y.%20Li&amp;author=C.J.%20Li\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref10\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib11\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib11\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[11]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">X. Li, N. Ma, J. Xu, Y. Zhang, P. Yang, X. Su, Y. Xing, N. An, F. Yang, G. Zhang, L. Zhang, Y. Xing<\/div>\n<div id=\"ref-id-sbref11\" class=\"title text-m\">Ferroptosis\uc758 \ud45c\uc801\ud654: \ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc758 \ubcd1\ub9ac\ud559\uc801 \uba54\ucee4\ub2c8\uc998 \ubc0f \uce58\ub8cc<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc0b0\ud654\ubb3c. Med Cell Longev., 2021(2021), \uc870\ud56d 1587922,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1155\/2021\/1587922\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1155\/2021\/1587922<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85118990959&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref11\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Targeting%20Ferroptosis%3A%20Pathological%20Mechanism%20and%20Treatment%20of%20Ischemia-Reperfusion%20Injury&amp;publication_year=2021&amp;author=X.%20Li&amp;author=N.%20Ma&amp;author=J.%20Xu&amp;author=Y.%20Zhang&amp;author=P.%20Yang&amp;author=X.%20Su&amp;author=Y.%20Xing&amp;author=N.%20An&amp;author=F.%20Yang&amp;author=G.%20Zhang&amp;author=L.%20Zhang&amp;author=Y.%20Xing\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref11\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib12\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib12\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[12]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">M. Mahjoubin-Tehran, S. Rezaei, A. Jesmani, N. Birang, K. Morshedi, H. Khanbabaei, H. Khan, A. Piranviseh, M. Nejati, M. Aschner, H. Mirzaei<\/div>\n<div id=\"ref-id-sbref12\" class=\"title text-m\">\ub1cc\uc878\uc911 \ubc1c\ubcd1\uc758 \uc0c8\ub85c\uc6b4 \ud6c4\uc131\uc720\uc804\uc801 \uc5ed\ud560: \ube44\ucf54\ub529 RNA\uc5d0\uc11c \uc5d1\uc18c\uc880 \ube44\ucf54\ub529 RNA\uae4c\uc9c0<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ubc14\uc774\uc624\uba54\ub4dc. Pharm., 140 (2021), \uc870\ud56d 111753,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.biopha.2021.111753\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.biopha.2021.111753<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332221005357\/pdfft?md5=13a6710773ddbd431c3757f9058711d2&amp;pid=1-s2.0-S0753332221005357-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref12\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332221005357\" aria-describedby=\"ref-id-sbref12\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85108373807&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref12\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=New%20epigenetic%20players%20in%20stroke%20pathogenesis%3A%20From%20non-coding%20RNAs%20to%20exosomal%20non-coding%20RNAs&amp;publication_year=2021&amp;author=M.%20Mahjoubin-Tehran&amp;author=S.%20Rezaei&amp;author=A.%20Jesmani&amp;author=N.%20Birang&amp;author=K.%20Morshedi&amp;author=H.%20Khanbabaei&amp;author=H.%20Khan&amp;author=A.%20Piranviseh&amp;author=M.%20Nejati&amp;author=M.%20Aschner&amp;author=H.%20Mirzaei\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref12\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib13\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib13\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[13]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">K. Yang, L. Zeng, A. Ge, S. Wang, J. Zeng, X. Yuan, Z. Mei, G. Wang, J. Ge<\/div>\n<div id=\"ref-id-sbref13\" class=\"title text-m\">\ub1cc\uacbd\uc0c9\/\ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1 \uc2dc \uc2e0\uacbd\uc5fc\uc99d \ubc0f \uba74\uc5ed\uc870\uc808\uc5d0 \uc788\uc5b4\uc11c non-coding RNA\uc758 \uc5f0\uad6c \uc9c4\ud589 \uc0c1\ud669\uc744 \uccb4\uacc4\uc801\uc73c\ub85c \uace0\ucc30<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc55e\ucabd. Immunol., 13(2022), \uc870\ud56d 930171,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.3389\/fimmu.2022.930171\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.3389\/fimmu.2022.930171<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85140346409&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref13\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=A%20systematic%20review%20of%20theresearch%20progress%20of%20non-coding%20RNAin%20neuroinflammation%20and%20immuneregulation%20in%20cerebral%20infarctionischemia-reperfusion%20injury&amp;publication_year=2022&amp;author=K.%20Yang&amp;author=L.%20Zeng&amp;author=A.%20Ge&amp;author=S.%20Wang&amp;author=J.%20Zeng&amp;author=X.%20Yuan&amp;author=Z.%20Mei&amp;author=G.%20Wang&amp;author=J.%20Ge\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref13\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib14\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib14\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[14]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">K. Yang, L. Zeng, X. Yuan, S. Wang, A. Ge, H. Xu, J. Zeng, J. Ge<\/div>\n<div id=\"ref-id-sbref14\" class=\"title text-m\">\ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc5d0\uc11c \uc0b0\ud654\uc2a4\ud2b8\ub808\uc2a4\ub97c \uc870\uc808\ud558\ub294 \ud398\ub85c\ud504\ud1a0\uc2dc\uc2a4\uc758 \uae30\uc804\uacfc \ucc9c\uc5f0\uc57d\ub9ac\ud65c\uc131\uc131\ubd84\uc758 \uc870\uc808\uae30\uc804<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ubc14\uc774\uc624\uba54\ub4dc. Pharm., 154 (2022), \uc870\ud56d 113611,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.biopha.2022.113611\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.biopha.2022.113611<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222010009\/pdfft?md5=c10c64d3830cfc66d624f7112443f8c0&amp;pid=1-s2.0-S0753332222010009-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref14\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222010009\" aria-describedby=\"ref-id-sbref14\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85137285700&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref14\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20mechanism%20of%20ferroptosis%20regulating%20oxidative%20stress%20in%20ischemic%20stroke%20and%20the%20regulation%20mechanism%20of%20natural%20pharmacological%20active%20components&amp;publication_year=2022&amp;author=K.%20Yang&amp;author=L.%20Zeng&amp;author=X.%20Yuan&amp;author=S.%20Wang&amp;author=A.%20Ge&amp;author=H.%20Xu&amp;author=J.%20Zeng&amp;author=J.%20Ge\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref14\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib15\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib15\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[15]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">PJ \ucf08\ub9ac, R. Lemmens, G. Tsivgoulis<\/div>\n<div id=\"ref-id-sbref15\" class=\"title text-m\">\uc5fc\uc99d \ubc0f \ub1cc\uc878\uc911 \uc704\ud5d8: \uc608\ubc29\uc744 \uc704\ud55c \uc0c8\ub85c\uc6b4 \ubaa9\ud45c<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ub1cc\uc878\uc911, 52 (8) (2021), pp. 2697-2706,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1161\/STROKEAHA.121.034388\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1161\/STROKEAHA.121.034388<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85111435034&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref15\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Inflammation%20and%20stroke%20risk%3A%20a%20new%20target%20for%20prevention&amp;publication_year=2021&amp;author=P.J.%20Kelly&amp;author=R.%20Lemmens&amp;author=G.%20Tsivgoulis\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref15\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib16\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib16\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[16]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">D. Levard, I. Buendia, A. Lanquetin, M. Glavan, D. Vivien, M. Rubio<\/div>\n<div id=\"ref-id-sbref16\" class=\"title text-m\">\ub1cc\uc878\uc911 \uc5f0\uad6c\uc758 \uacf5\ubc31 \uba54\uc6b0\uae30: \uc5fc\uc99d\uacfc \uba74\uc5ed\uc5d0 \ucd08\uc810<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ub1cc \ud589\ub3d9. Immun., 91(2021), pp. 649-667,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.bbi.2020.09.025\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.bbi.2020.09.025<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0889159120314835\/pdfft?md5=7f20c8efadebc4ba2e72b6ff156a4240&amp;pid=1-s2.0-S0889159120314835-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref16\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0889159120314835\" aria-describedby=\"ref-id-sbref16\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85092252055&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref16\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Filling%20the%20gaps%20on%20stroke%20research%3A%20Focus%20on%20inflammation%20and%20immunity&amp;publication_year=2021&amp;author=D.%20Levard&amp;author=I.%20Buendia&amp;author=A.%20Lanquetin&amp;author=M.%20Glavan&amp;author=D.%20Vivien&amp;author=M.%20Rubio\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref16\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib17\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib17\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[17]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">J. \uc2dc, W. \uac00\uc624, F. \uc0e4\uc624<\/div>\n<div id=\"ref-id-sbref17\" class=\"title text-m\">\uc5f4\ubd84\ud574\uc99d: \uac00\uc2a4\ub354\ubbfc \ub9e4\uac1c \ud504\ub85c\uadf8\ub7a8 \uad34\uc0ac\uc131 \uc138\ud3ec \uc0ac\uba78<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Trends Biochem Sci., 42 (4) (2017), pp. 245-254,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.tibs.2016.10.004\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.tibs.2016.10.004<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0968000416301827\/pdfft?md5=78b194c8f2c41e414a54a46eab39f285&amp;pid=1-s2.0-S0968000416301827-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref17\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0968000416301827\" aria-describedby=\"ref-id-sbref17\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85007439966&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref17\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Pyroptosis%3A%20Gasdermin-Mediated%20Programmed%20Necrotic%20Cell%20Death&amp;publication_year=2017&amp;author=J.%20Shi&amp;author=W.%20Gao&amp;author=F.%20Shao\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref17\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib18\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib18\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[18]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Y. Fang, S. Tian, Y. Pan, W. Li, Q. Wang, Y. Tang, T. Yu, X. Wu, Y. Shi, P. Ma, Y. Shu<\/div>\n<div id=\"ref-id-sbref18\" class=\"title text-m\">\ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4(Pyroptosis): \uc554\uc758 \uc0c8\ub85c\uc6b4 \uac1c\ucc99\uc9c0<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ubc14\uc774\uc624\uba54\ub4dc. Pharm., 121 (2020), \uc870\ud56d 109595,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.biopha.2019.109595\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.biopha.2019.109595<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332219352175\/pdfft?md5=7b9dcf8c8439cdfb441f17e4a6c467fb&amp;pid=1-s2.0-S0753332219352175-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref18\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332219352175\" aria-describedby=\"ref-id-sbref18\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85074467088&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref18\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Pyroptosis%3A%20A%20new%20frontier%20in%20cancer&amp;publication_year=2020&amp;author=Y.%20Fang&amp;author=S.%20Tian&amp;author=Y.%20Pan&amp;author=W.%20Li&amp;author=Q.%20Wang&amp;author=Y.%20Tang&amp;author=T.%20Yu&amp;author=X.%20Wu&amp;author=Y.%20Shi&amp;author=P.%20Ma&amp;author=Y.%20Shu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref18\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib19\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib19\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[19]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">YS Feng, ZX Tan, LY Wu, F. Dong, F. Zhang<\/div>\n<div id=\"ref-id-sbref19\" class=\"title text-m\">\uc2e0\uacbd\ud1f4\ud589\uc131 \uc9c8\ud658 \uce58\ub8cc\uc5d0 NLRP3 \uc778\ud50c\ub77c\ub9c8\uc19c\uc758 \uad00\uc5ec<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ubc14\uc774\uc624\uba54\ub4dc. Pharm., 138 (2021), \uc870\ud56d 111428,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.biopha.2021.111428\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.biopha.2021.111428<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332221002134\/pdfft?md5=71fc42926442dd2691967ef65289e469&amp;pid=1-s2.0-S0753332221002134-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref19\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332221002134\" aria-describedby=\"ref-id-sbref19\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85101767999&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref19\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20involvement%20of%20NLRP3%20inflammasome%20in%20the%20treatment%20of%20neurodegenerative%20diseases&amp;publication_year=2021&amp;author=Y.S.%20Feng&amp;author=Z.X.%20Tan&amp;author=L.Y.%20Wu&amp;author=F.%20Dong&amp;author=F.%20Zhang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref19\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib20\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib20\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[20]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">J. Chen, Z. Wei, K. Fu, Y. Duan, M. Zhang, K. Li, T. Guo, R. Yin<\/div>\n<div id=\"ref-id-sbref20\" class=\"title text-m\">\ub09c\uc18c\uc554\uc758 \ube44\uc138\ud3ec\uc0ac\uba78 \uc138\ud3ec\uc0ac: \uce58\ub8cc, \uc800\ud56d\uc131 \ubc0f \uc608\ud6c4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ubc14\uc774\uc624\uba54\ub4dc. Pharm., 150 (2022), \uc870\ud56d 112929,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.biopha.2022.112929\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.biopha.2022.112929<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222003183\/pdfft?md5=056cbffef01439e4b2fd4ed8e4300fd4&amp;pid=1-s2.0-S0753332222003183-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref20\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222003183\" aria-describedby=\"ref-id-sbref20\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85129378630&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref20\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Non-apoptotic%20cell%20death%20in%20ovarian%20cancer%3A%20Treatment%2C%20resistance%20and%20prognosis&amp;publication_year=2022&amp;author=J.%20Chen&amp;author=Z.%20Wei&amp;author=K.%20Fu&amp;author=Y.%20Duan&amp;author=M.%20Zhang&amp;author=K.%20Li&amp;author=T.%20Guo&amp;author=R.%20Yin\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref20\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib21\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib21\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[21]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">K. Du, M. He, D. Zhao, Y. Wang, C. Ma, H. Liang, W. Wang, D. Min, L. Xue, F. Guo<\/div>\n<div id=\"ref-id-sbref21\" class=\"title text-m\">\uac04\uc9c8\uc911\ucca9\uc99d\uc758 \uc138\ud3ec\uc0ac\uba78 \uacbd\ub85c \uba54\ucee4\ub2c8\uc998 \ubc0f \uad00\ub828 \uce58\ub8cc\uc81c<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ubc14\uc774\uc624\uba54\ub4dc. Pharm., 149 (2022), \uc870\ud56d 112875,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.biopha.2022.112875\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.biopha.2022.112875<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222002645\/pdfft?md5=8afe782b3281b7d53f8a3fd3ca1cf095&amp;pid=1-s2.0-S0753332222002645-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref21\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222002645\" aria-describedby=\"ref-id-sbref21\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85127230234&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref21\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Mechanism%20of%20cell%20death%20pathways%20in%20status%20epilepticus%20and%20related%20therapeutic%20agents&amp;publication_year=2022&amp;author=K.%20Du&amp;author=M.%20He&amp;author=D.%20Zhao&amp;author=Y.%20Wang&amp;author=C.%20Ma&amp;author=H.%20Liang&amp;author=W.%20Wang&amp;author=D.%20Min&amp;author=L.%20Xue&amp;author=F.%20Guo\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref21\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib22\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib22\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[22]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">X. Gou, D. Xu, F. Li, K. Hou, W. Fang, Y. Li<\/div>\n<div id=\"ref-id-sbref22\" class=\"title text-m\">\ub1cc\uc878\uc911\uc758 \uc5f4\ubcd1\uc99d - \uc9c8\ubcd1 \uba54\ucee4\ub2c8\uc998 \ubc0f \uce58\ub8cc \uc804\ub7b5\uc5d0 \ub300\ud55c \uc0c8\ub85c\uc6b4 \ud1b5\ucc30\ub825<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. PhysiolBiochem, 77(4)(2021), pp. 511-529,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1007\/s13105-021-00817-w\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1007\/s13105-021-00817-w<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85105383446&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref22\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Pyroptosis%20in%20stroke-new%20insights%20into%20disease%20mechanisms%20and%20therapeutic%20strategies&amp;publication_year=2021&amp;author=X.%20Gou&amp;author=D.%20Xu&amp;author=F.%20Li&amp;author=K.%20Hou&amp;author=W.%20Fang&amp;author=Y.%20Li\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref22\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib23\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib23\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[23]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">A. Ye, W. Li, L. Zhou, L. Ao, W. Fang, Y. Li<\/div>\n<div id=\"ref-id-sbref23\" class=\"title text-m\">\ud5c8\ud608\uc131 \ub1cc\uc878\uc911 \uc190\uc0c1\uc744 \uc870\uc808\ud558\uae30 \uc704\ud55c \ubc1c\uc5f4\uc99d\uc758 \ud45c\uc801\ud654: \ubd84\uc790 \uba54\ucee4\ub2c8\uc998 \ubc0f \uc804\uc784\uc0c1 \uc99d\uac70<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Brain Res Bull., 165(2020), \ud398\uc774\uc9c0 146-160,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.brainresbull.2020.10.009\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.brainresbull.2020.10.009<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0361923020306663\/pdfft?md5=288065b6f5462f97612087e8ee79aa66&amp;pid=1-s2.0-S0361923020306663-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref23\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0361923020306663\" aria-describedby=\"ref-id-sbref23\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85092942666&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref23\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Targeting%20pyroptosis%20to%20regulate%20ischemic%20stroke%20injury%3A%20Molecular%20mechanisms%20and%20preclinical%20evidences&amp;publication_year=2020&amp;author=A.%20Ye&amp;author=W.%20Li&amp;author=L.%20Zhou&amp;author=L.%20Ao&amp;author=W.%20Fang&amp;author=Y.%20Li\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref23\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib24\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib24\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[24]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">B. Tang, X. She, CQ Deng<\/div>\n<div id=\"ref-id-sbref24\" class=\"title text-m\">\ub300\ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958 \uc950 \ubaa8\ub378\uc5d0\uc11c \uc544\uc2a4\ud2b8\ub77c\uac08\ub85c\uc0ac\uc774\ub4dc IV\uc640 \uc0bc\uce60\uc778\uc0bc \uc0ac\ud3ec\ub2cc\uc758 \uc870\ud569\uc774 \ubc1c\uc5f4\uc99d \ubc0f \uad34\uc0ac\uc5d0 \ubbf8\uce58\ub294 \uc601\ud5a5<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud2b9\uae09. \uac70\uae30. Med, 22(4)(2021), p. 1123,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.3892\/etm.2021.10557\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.3892\/etm.2021.10557<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Effect%20of%20the%20combination%20of%20astragaloside%20IV%20and%20Panax%20notoginseng%20saponins%20on%20pyroptosis%20and%20necroptosis%20in%20rat%20models%20of%20cerebral%20ischemia-reperfusion&amp;publication_year=2021&amp;author=B.%20Tang&amp;author=X.%20She&amp;author=C.Q.%20Deng\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref24\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib25\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib25\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[25]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Y. She, L. Shao, Y. Zhang, Y. Hao, Y. Cai, Z. Cheng, C. Deng, X. Liu<\/div>\n<div id=\"ref-id-sbref25\" class=\"title text-m\">\uc950\uc758 \ub1cc\ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1 \ud6c4 \ubc1c\uc5f4\uc99d\uc5d0 \ub300\ud55c \ubd80\uc591\ud658\uc624\ud0d5\uc758 \ubc30\ub2f9\uccb4\uc758 \uc2e0\uacbd\ubcf4\ud638 \ud6a8\uacfc<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. Ethnopharmacol., 242(2019), \uc870\ud56d 112051,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.jep.2019.112051\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.jep.2019.112051<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0378874119306816\/pdfft?md5=20e0d49e6cd3b78abd9bc6de80190401&amp;pid=1-s2.0-S0378874119306816-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref25\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0378874119306816\" aria-describedby=\"ref-id-sbref25\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85068926621&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref25\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Neuroprotective%20effect%20of%20glycosides%20in%20BuyangHuanwu%20Decoction%20on%20pyroptosis%20following%20cerebral%20ischemia-reperfusion%20injury%20in%20rats&amp;publication_year=2019&amp;author=Y.%20She&amp;author=L.%20Shao&amp;author=Y.%20Zhang&amp;author=Y.%20Hao&amp;author=Y.%20Cai&amp;author=Z.%20Cheng&amp;author=C.%20Deng&amp;author=X.%20Liu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref25\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib26\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib26\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[26]<\/span><\/a><\/span>\n<div class=\"other-ref\">Tang Biao, Tang Wenjing, Dai Ziwei, She Xu, Deng Changqing. \uc778\uc0bc \uc0ac\ud3ec\ub2cc\uc740 SH-SY5Y \uc138\ud3ec\uc758 \uc800\uc0b0\uc18c\uc99d-\uc800\ud608\ub2f9\/\uc7ac\uc0b0\uc18c\ud654 \ubc0f \uc7ac\ud608\ub2f9 \uc720\ubc1c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc5b5\uc81c\ud569\ub2c8\ub2e4. \uc911\uad6d \ubcd1\ud0dc\uc0dd\ub9ac\ud559 \uc800\ub110, 2020, 36 (07):1178\u20131184.(\uc911\uad6d\uc5b4).<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar?q=Tang%20Biao%2C%20Tang%20Wenjing%2C%20Dai%20Ziwei%2C%20She%20Xu%2C%20Deng%20Changqing.%20Panax%20notoginseng%20saponins%20inhibit%20hypoxia-hypoglycemia%2Freoxygenation%20and%20reglycemia-induced%20pyroptosis%20of%20SH-SY5Y%20cells.%20Chinese%20Journal%20of%20Pathophysiology%2C%202020%2C%2036%20(07)%3A1178%E2%80%931184.%EF%BC%88in%20chinese%EF%BC%89.\" target=\"_blank\" rel=\"noopener noreferrer\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib27\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib27\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[27]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">\ub9ac\uc2e0<\/div>\n<div id=\"ref-id-sbref26\" class=\"title text-m\">\uc138\ud3ec \ubc1c\uc5f4 \uba54\ucee4\ub2c8\uc998\uc744 \uae30\ubc18\uc73c\ub85c \uc800\ud608\ub2f9 \ubc0f \uc800\uc0b0\uc18c\uc99d\uc774 \uc788\ub294 PC12 \uc138\ud3ec\uc5d0 \ub300\ud55c \uc2e0\ub098\uc624 \ud478\uc704\uc548 \ub2ec\uc784\uc758 \ubcf4\ud638 \ud6a8\uacfc \ud0d0\uc0c9 [D]<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud6c4\ub09c\ub300\ud559\uad50 \uc804\ud1b5. \ud131. \uba54\ub4dc. (2019),\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.27138\/d.cnki.ghuzc.2019.000152\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.27138\/d.cnki.ghuzc.2019.000152<\/span><\/a><\/div>\n<div class=\"comment\">(\uc911\uad6d\uc5b4\ub85c)<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Exploring%20the%20protective%20effect%20of%20Shennao%20Fuyuan%20decoction%20on%20PC12%20cells%20with%20hypoglycemia%20and%20hypoxia%20based%20on%20the%20mechanism%20of%20cell%20pyroptosis%20D&amp;publication_year=2019&amp;author=Li%20Xin\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref26\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib28\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib28\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[28]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">S. Xia, P. Yang, F. Li, Q. Yu, W. Kuang, Y. Zhu, J. Lu, H. Wu, L. Li, H. Huang<\/div>\n<div id=\"ref-id-sbref27\" class=\"title text-m\">\ucc28\uc774\ud6c4\ub871\uad6c\ubb3c\ub9ac\ub2ec\uc784\uc740 \ud574\ub9c8 \uc2e0\uacbd\uc138\ud3ec\uc758 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uac1c\uc120\ud558\uc5ec \uc950\uc758 \ud56d\uac04\uc9c8 \ud6a8\uacfc\ub97c \ub098\ud0c0\ub0c5\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. Ethnopharmacol., 270(2021), \uc870\ud56d 113794,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.jep.2021.113794\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.jep.2021.113794<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0378874121000209\/pdfft?md5=83eecc2479eefb000f87cb4675227f8f&amp;pid=1-s2.0-S0378874121000209-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref27\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0378874121000209\" aria-describedby=\"ref-id-sbref27\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85099615470&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref27\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Chaihu-Longgu-Muli%20Decoction%20exerts%20an%20antiepileptic%20effect%20in%20rats%20by%20improving%20pyroptosis%20in%20hippocampal%20neurons&amp;publication_year=2021&amp;author=S.%20Xia&amp;author=P.%20Yang&amp;author=F.%20Li&amp;author=Q.%20Yu&amp;author=W.%20Kuang&amp;author=Y.%20Zhu&amp;author=J.%20Lu&amp;author=H.%20Wu&amp;author=L.%20Li&amp;author=H.%20Huang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref27\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib29\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib29\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[29]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">L. Galluzzi, I. Vitale, SA Aaronson,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref28\" class=\"title text-m\">\uc138\ud3ec \uc0ac\uba78\uc758 \ubd84\uc790 \uba54\ucee4\ub2c8\uc998: 2018\ub144 \uc138\ud3ec \uc0ac\uba78 \uba85\uba85\ubc95 \uc704\uc6d0\ud68c\uc758 \uad8c\uc7a5 \uc0ac\ud56d<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Cell Death Different., 25 (2018), pp. 486-541<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/doi.org\/10.1038\/s41418-017-0012-4\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref28\"><span class=\"anchor-text\">CrossRef<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85036533976&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref28\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Molecular%20mechanisms%20of%20cell%20death%3A%20recommendations%20of%20the%20Nomenclature%20Committee%20on%20Cell%20Death%202018&amp;publication_year=2018&amp;author=L.%20Galluzzi&amp;author=I.%20Vitale&amp;author=S.A.%20Aaronson\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref28\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib30\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib30\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[30]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">R. \uc2f1, A. \ub808\ud0c0\uc774, K. \uc0ac\ub85c\uc2dc\ud06c<\/div>\n<div id=\"ref-id-sbref29\" class=\"title text-m\">\uac74\uac15\uacfc \uc9c8\ubcd1\uc758 \uc138\ud3ec\uc0ac\uba78 \uc870\uc808: BCL-2 \uacc4\uc5f4 \ub2e8\ubc31\uc9c8\uc758 \uade0\ud615 \uc791\uc6a9<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Nat. \ubab0 \ubaa9\uc0ac. Cell Biol., 20(2019), pp. 175-193<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/doi.org\/10.1038\/s41580-018-0089-8\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref29\"><span class=\"anchor-text\">CrossRef<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85060225102&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref29\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Regulation%20of%20apoptosis%20in%20health%20and%20disease%3A%20the%20balancing%20act%20of%20BCL-2%20family%20proteins&amp;publication_year=2019&amp;author=R.%20Singh&amp;author=A.%20Letai&amp;author=K.%20Sarosiek\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref29\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib31\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib31\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[31]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">P. Yu, X. Zhang, N. Liu, L. Tang, C. Peng, X. Chen<\/div>\n<div id=\"ref-id-sbref30\" class=\"title text-m\">Pyroptosis : \uba54\ucee4\ub2c8\uc998 \ubc0f \uc9c8\ubcd1<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc2e0\ud638 \uc804\ub2ec. Target Ther., 6(1)(2021), p. 128,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1038\/s41392-021-00507-5\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1038\/s41392-021-00507-5<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85103600758&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref30\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Pyroptosis%3A%20mechanisms%20and%20diseases&amp;publication_year=2021&amp;author=P.%20Yu&amp;author=X.%20Zhang&amp;author=N.%20Liu&amp;author=L.%20Tang&amp;author=C.%20Peng&amp;author=X.%20Chen\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref30\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib32\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib32\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[32]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">X. Chen, WT He, L. Hu,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref31\" class=\"title text-m\">Pyroptosis\ub294 \ube44\uc120\ud0dd\uc801\uc778 gasdermin-D \uae30\uacf5\uc5d0 \uc758\ud574 \uc720\ubc1c\ub418\uba70 \uadf8 \ud615\ud0dc\ub294 MLKL \ucc44\ub110 \ub9e4\uac1c \uad34\uc0ac\uc640 \ub2e4\ub985\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Cell Res, 26(2016), pp. 1007-1020<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/doi.org\/10.1038\/cr.2016.100\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref31\"><span class=\"anchor-text\">CrossRef<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84984822442&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref31\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Pyroptosis%20is%20driven%20by%20non-selective%20gasdermin-D%20pore%20and%20its%20morphology%20is%20different%20from%20MLKL%20channel-mediated%20necroptosis&amp;publication_year=2016&amp;author=X.%20Chen&amp;author=W.T.%20He&amp;author=L.%20Hu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref31\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib33\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib33\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[33]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">D. Tang, R. Kang, TV Berghe, P. Vandenabeele, G. Kroemer<\/div>\n<div id=\"ref-id-sbref32\" class=\"title text-m\">\uc870\uc808\ub41c \uc138\ud3ec \uc0ac\uba78\uc758 \ubd84\uc790 \uae30\uacc4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Cell Res, 29(5)(2019), pp. 347-364<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/doi.org\/10.1038\/s41422-019-0164-5\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref32\"><span class=\"anchor-text\">CrossRef<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85063997734&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref32\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20molecular%20machinery%20of%20regulated%20cell%20death&amp;publication_year=2019&amp;author=D.%20Tang&amp;author=R.%20Kang&amp;author=T.V.%20Berghe&amp;author=P.%20Vandenabeele&amp;author=G.%20Kroemer\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref32\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib34\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib34\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[34]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">EA \ubbf8\uc544\uc624, DP \ub9c8\uc624, N. Yudkovsky,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref33\" class=\"title text-m\">NLRC4 inflammasome\uc744 \ud1b5\ud55c III\ud615 \ubd84\ube44\uae30\uad00\uc758 \uc120\ucc9c\uba74\uc5ed \uac80\ucd9c<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc9c4\ud589 Natl. Acad. Sci., 107(7)(2010), pp. 3076-3080<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/doi.org\/10.1073\/pnas.0913087107\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref33\"><span class=\"anchor-text\">CrossRef<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-77649241461&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref33\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Innate%20immune%20detection%20of%20the%20type%20III%20secretion%20apparatus%20through%20the%20NLRC4%20inflammasome&amp;publication_year=2010&amp;author=E.A.%20Miao&amp;author=D.P.%20Mao&amp;author=N.%20Yudkovsky\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref33\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib35\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib35\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[35]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">W. Shao, G. Yeretssian, K. Doiron, SN Hussain, M. Saleh<\/div>\n<div id=\"ref-id-sbref34\" class=\"title text-m\">\uce74\uc2a4\ud30c\uc81c-1 \ub2e4\uc774\uc81c\ud1b0\uc740 \uac10\uc5fc \ubc0f \ud328\ud608\uc131 \uc1fc\ud06c \ub3d9\uc548 \ud574\ub2f9\uacfc\uc815 \uacbd\ub85c\ub97c \ud45c\uc801\uc73c\ub85c \uc2dd\ubcc4\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. Biol. Chem., 282(50)(2007), pp. 36321-36329<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S002192581846084X\/pdfft?md5=c8d11d6959add4b1b376b660f184c344&amp;pid=1-s2.0-S002192581846084X-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref34\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S002192581846084X\" aria-describedby=\"ref-id-sbref34\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-37549002511&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref34\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20caspase-1%20digestome%20identifies%20the%20glycolysis%20pathway%20as%20a%20target%20during%20infection%20and%20septic%20shock&amp;publication_year=2007&amp;author=W.%20Shao&amp;author=G.%20Yeretssian&amp;author=K.%20Doiron&amp;author=S.N.%20Hussain&amp;author=M.%20Saleh\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref34\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib36\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib36\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[36]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Y. \uc655, W. \uac00\uc624, X. \uc2dc,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref35\" class=\"title text-m\">\ud654\ud559\uc694\ubc95 \uc57d\ubb3c\uc740 \uac00\uc2a4\ub354\ubbfc\uc758 \uce74\uc2a4\ud30c\uc81c-3 \uc808\ub2e8\uc744 \ud1b5\ud574 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc720\ub3c4\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc790\uc5f0, 547(7661)(2017), pp. 99-103<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Chemotherapy%20drugs%20induce%20pyroptosis%20through%20caspase-3%20cleavage%20of%20a%20gasdermin&amp;publication_year=2017&amp;author=Y.%20Wang&amp;author=W.%20Gao&amp;author=X.%20Shi\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref35\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib37\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib37\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[37]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">PE Czabotar, G. Lessene, A. Strasser, JM Adams<\/div>\n<div id=\"ref-id-sbref36\" class=\"title text-m\">BCL-2 \ub2e8\ubc31\uc9c8\uad70\uc5d0 \uc758\ud55c \uc138\ud3ec\uc0ac\uba78\uc758 \uc870\uc808: \uc0dd\ub9ac\ud559\uacfc \uce58\ub8cc\uc5d0 \ub300\ud55c \ud568\uc758<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc790\uc5f0 \ubaa9\uc0ac Mol. Cell Biol., 15(1)(2014), pp. 49-63<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/doi.org\/10.1038\/nrm3722\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref36\"><span class=\"anchor-text\">CrossRef<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84890909335&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref36\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Control%20of%20apoptosis%20by%20the%20BCL-2%20protein%20family%3A%20implications%20for%20physiology%20and%20therapy&amp;publication_year=2014&amp;author=P.E.%20Czabotar&amp;author=G.%20Lessene&amp;author=A.%20Strasser&amp;author=J.M.%20Adams\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref36\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib38\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib38\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[38]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">S. Goldar, MS Khaniani, SM Derakhshan, B. Baradaran<\/div>\n<div id=\"ref-id-sbref37\" class=\"title text-m\">\uc138\ud3ec \uc0ac\uba78\uc758 \ubd84\uc790 \uba54\ucee4\ub2c8\uc998\uacfc \uc554 \ubc1c\uc0dd \ubc0f \uce58\ub8cc\uc5d0\uc11c\uc758 \uc5ed\ud560<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc544\uc2dc\uc544\ud329. J. Cancer Prev., 16(6)(2015), pp. 2129-2144<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84929224850&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref37\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Molecular%20mechanisms%20of%20apoptosis%20and%20roles%20in%20cancer%20development%20and%20treatment&amp;publication_year=2015&amp;author=S.%20Goldar&amp;author=M.S.%20Khaniani&amp;author=S.M.%20Derakhshan&amp;author=B.%20Baradaran\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref37\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib39\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib39\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[39]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">A. \ub370\ub77c\ud06c\uc0e8, Z. \uccb8, C. \ubc18 \uc6e8\uc2a4<\/div>\n<div id=\"ref-id-sbref38\" class=\"title text-m\">\uc678\uc778\uc131 \ubc0f \ub0b4\uc778\uc131 \uc138\ud3ec \uc0ac\uba78 \uacbd\ub85c\uc758 \uc870\uc808\uc774 \uc644\ud654\ub41c \uc554\uc5d0\uc11c \uc138\ud3ec\uc0ac\uba78 \ub2e8\ubc31\uc9c8\uc758 \uc5b5\uc81c\uc81c\ub97c \ud45c\uc801\uc73c\ub85c \ud558\ub294 \uce58\ub8cc\uc6a9 \uc18c\ubd84\uc790<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud074\ub9b0. Cancer Res., 23 (6) (2017), pp. 1379-1387<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85016152858&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref38\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Therapeutic%20small%20molecules%20target%20inhibitor%20of%20apoptosis%20proteins%20in%20cancers%20with%20deregulation%20of%20extrinsic%20and%20intrinsic%20cell%20death%20pathways&amp;publication_year=2017&amp;author=A.%20Derakhshan&amp;author=Z.%20Chen&amp;author=C.%20Van%20Waes\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref38\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib40\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib40\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[40]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">A. \ub9c1\ucee4\ub9cc, DR \uadf8\ub9b0<\/div>\n<div id=\"ref-id-sbref39\" class=\"title text-m\">\uad34\uc0ac\uc99d<\/div>\n<\/div>\n<div class=\"host u-font-sans\">N.Engl. J. Med., 370(5)(2014), pp. 455-465<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84893149021&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref39\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Necroptosis&amp;publication_year=2014&amp;author=A.%20Linkermann&amp;author=D.R.%20Green\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref39\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib41\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib41\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[41]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">JM \uba38\ud53c, PE Czabotar, JM Hildebrand,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref40\" class=\"title text-m\">\uc288\ub3c4\ud0a4\ub098\uc81c MLKL\uc740 \ubd84\uc790 \uc2a4\uc704\uce58 \uba54\ucee4\ub2c8\uc998\uc744 \ud1b5\ud574 \uad34\uc0ac\ub97c \ub9e4\uac1c\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uba74\uc5ed, 39(3)(2013), 443-453\ud398\uc774\uc9c0<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1074761313003488\/pdfft?md5=26462adb647b1c8367794e786f60115c&amp;pid=1-s2.0-S1074761313003488-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref40\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1074761313003488\" aria-describedby=\"ref-id-sbref40\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84884308522&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref40\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20pseudokinase%20MLKL%20mediates%20necroptosis%20via%20a%20molecular%20switch%20mechanism&amp;publication_year=2013&amp;author=J.M.%20Murphy&amp;author=P.E.%20Czabotar&amp;author=J.M.%20Hildebrand\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref40\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib42\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib42\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[42]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">S. \ud480\ub2e4<\/div>\n<div id=\"ref-id-sbref41\" class=\"title text-m\">\ub300\uccb4 \uc138\ud3ec \uc0ac\uba78 \uacbd\ub85c \ubc0f \uc138\ud3ec \ub300\uc0ac<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uad6d\uc81c J. Cell Biol., 2013(2013), \uc870\ud56d 463637<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84874603172&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref41\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Alternative%20cell%20death%20pathways%20and%20cell%20metabolism&amp;publication_year=2013&amp;author=S.%20Fulda\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref41\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib43\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib43\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[43]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Y. \uc7a5, X. \uccb8, C. Gueydan, J. \ud55c<\/div>\n<div id=\"ref-id-sbref42\" class=\"title text-m\">\ud504\ub85c\uadf8\ub7a8\ub41c \uc138\ud3ec \uc0ac\uba78 \ub3d9\uc548 \uc6d0\ud615\uc9c8\ub9c9 \ubcc0\ud654<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Cell Res, 28(1)(2018), pp. 9-21<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/doi.org\/10.1038\/cr.2017.133\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref42\"><span class=\"anchor-text\">CrossRef<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Plasma%20membrane%20changes%20during%20programmed%20cell%20deaths&amp;publication_year=2018&amp;author=Y.%20Zhang&amp;author=X.%20Chen&amp;author=C.%20Gueydan&amp;author=J.%20Han\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref42\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib44\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib44\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[44]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">SJ \ub515\uc2a8, BR \uc2a4\ud1a1\uc6f0<\/div>\n<div id=\"ref-id-sbref43\" class=\"title text-m\">\uc138\ud3ec\uc0ac\uba78\uc5d0\uc11c \ucca0\ubd84\uacfc \ud65c\uc131\uc0b0\uc18c\uc885\uc758 \uc5ed\ud560<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Nat. \ud654\ud559. Biol., 10 (2014), pp. 9-17,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1038\/nchembio.1416\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1038\/nchembio.1416<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84890922670&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref43\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20role%20of%20iron%20and%20reactive%20oxygen%20species%20in%20cell%20death&amp;publication_year=2014&amp;author=S.J.%20Dixon&amp;author=B.R.%20Stockwell\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref43\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib45\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib45\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[45]<\/span><\/a><\/span>\n<div class=\"other-ref\">Bogdan AR, Miyazawa M., Hashimoto K., Tsuji Y. \ucca0 \ud56d\uc0c1\uc131 \uc870\uc808\uc790: \ub300\uc0ac, \uc138\ud3ec \uc0ac\uba78 \ubc0f \uc9c8\ubcd1\uc758 \uc0c8\ub85c\uc6b4 \ud50c\ub808\uc774\uc5b4.<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar?q=Bogdan%20A.R.%2C%20Miyazawa%20M.%2C%20Hashimoto%20K.%2C%20Tsuji%20Y.%20Regulators%20of%20Iron%20Homeostasis%3A%20New%20Players%20in%20Metabolism%2C%20Cell%20Death%2C%20and%20Disease.\" target=\"_blank\" rel=\"noopener noreferrer\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib46\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib46\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[46]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">B. \ub77c\uc774, CH \uc6b0, CY \uc6b0, SF \ub8e8\uc624, JH \ub77c\uc774<\/div>\n<div id=\"ref-id-sbref44\" class=\"title text-m\">Ferroptosis \ubc0f\uc790\uac00 \uba74\uc5ed \uc9c8\ud658<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Front Immunol., 13(2022), \uc870\ud56d 916664,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.3389\/fimmu.2022.916664\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.3389\/fimmu.2022.916664<\/span><\/a><\/div>\n<div class=\"comment\">PMID: 35720308; PMCID:PMC9203688.<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85132268884&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref44\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Ferroptosis%20and%20autoimmune%20diseases&amp;publication_year=2022&amp;author=B.%20Lai&amp;author=C.H.%20Wu&amp;author=C.Y.%20Wu&amp;author=S.F.%20Luo&amp;author=J.H.%20Lai\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref44\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib47\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib47\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[47]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Z. \uccb8, J. \uc7a5, N. \ud478, L. \uccb8<\/div>\n<div id=\"ref-id-sbref45\" class=\"title text-m\">\ud608\uc561 \uc138\ud3ec \uad00\ub828 \uc9c8\ud658\uc758 \ud398\ub85c\ud504\ud1a0\uc2dc\uc2a4(ferroptosis) \ud45c\uc801\ud654<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. Drug Target, 30(3)(2022), pp. 244-258,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1080\/1061186X.2021.1971237\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1080\/1061186X.2021.1971237<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85113991336&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref45\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Targetting%20ferroptosis%20for%20blood%20cell-related%20diseases&amp;publication_year=2022&amp;author=Z.%20Chen&amp;author=J.%20Jiang&amp;author=N.%20Fu&amp;author=L.%20Chen\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref45\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib48\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib48\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[48]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">C. Jia, H. Chen, J. Zhang, K. Zhou, Y. Zhuge, C. Niu, J. Qiu, X. Rong, Z. Shi, J. Xiao, Y. Shi, M. Chu<\/div>\n<div id=\"ref-id-sbref46\" class=\"title text-m\">\uc2ec\ud608\uad00 \uc9c8\ud658\uc5d0\uc11c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc758 \uc5ed\ud560<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Int Immunopharmacol., 67(2019), pp. 311-318,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.intimp.2018.12.028\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.intimp.2018.12.028<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1567576918310439\/pdfft?md5=1ed3eb6c21c253058f135c8fa3bf70a6&amp;pid=1-s2.0-S1567576918310439-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref46\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1567576918310439\" aria-describedby=\"ref-id-sbref46\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85058449560&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref46\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Role%20of%20pyroptosis%20in%20cardiovascular%20diseases&amp;publication_year=2019&amp;author=C.%20Jia&amp;author=H.%20Chen&amp;author=J.%20Zhang&amp;author=K.%20Zhou&amp;author=Y.%20Zhuge&amp;author=C.%20Niu&amp;author=J.%20Qiu&amp;author=X.%20Rong&amp;author=Z.%20Shi&amp;author=J.%20Xiao&amp;author=Y.%20Shi&amp;author=M.%20Chu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref46\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib49\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib49\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[49]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">L. \ud5c8\uc6b0, Z. \uc591, Z. \uc655,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref47\" class=\"title text-m\">NLRP3\/ASC \ub9e4\uac1c \ud3d0\ud3ec \ub300\uc2dd\uc138\ud3ec \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub294 \uc2ec\ud3d0 \uc6b0\ud68c\uc220\ub85c \uc720\ubc1c\ub41c \uae09\uc131 \ud3d0 \uc190\uc0c1\uc5d0\uc11c HMGB1 \ubd84\ube44\ub97c \ud5a5\uc0c1\uc2dc\ud0b5\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ub7a9. \uc870\uc0ac\ud558\ub2e4. ; J. Tech. Methods Pathol., 98 (8) (2018), pp. 1052-1064,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1038\/s41374-018-0073-0\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1038\/s41374-018-0073-0<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0023683722011035\/pdfft?md5=52cf1adba7ef6f4348e6632a9f8e01c9&amp;pid=1-s2.0-S0023683722011035-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref47\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0023683722011035\" aria-describedby=\"ref-id-sbref47\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85048177565&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref47\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=NLRP3ASC-mediated%20alveolar%20macrophage%20pyroptosis%20enhances%20HMGB1%20secretion%20in%20acute%20lung%20injury%20induced%20by%20cardiopulmonary%20bypass&amp;publication_year=2018&amp;author=L.%20Hou&amp;author=Z.%20Yang&amp;author=Z.%20Wang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref47\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib50\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib50\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[50]<\/span><\/a><\/span><span class=\"reference\"><span class=\"label\">(\u314f)<\/span><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Z. Hu, J. \ucc28\uc774<\/div>\n<div id=\"ref-id-sbref48\" class=\"title text-m\">NLR \uc5fc\uc99d\ubcf5\ud569\uccb4 \uc870\ub9bd \ubc0f \uc2e0\ud638 \uc804\ub2ec\uc758 \uad6c\uc870\uc801 \uba54\ucee4\ub2c8\uc998<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud604\uc7ac \ub9e8 \uc704. Microbiol Immunol., 397(2016), pp. 23-42<\/div>\n<div class=\"comment\">10<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/doi.org\/10.1007\/978-3-319-41171-2_2\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref48\"><span class=\"anchor-text\">CrossRef<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84982688438&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref48\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Structural%20mechanisms%20in%20NLR%20inflammasome%20assembly%20and%20signaling&amp;publication_year=2016&amp;author=Z.%20Hu&amp;author=J.%20Chai\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref48\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<p><span class=\"reference\"><span class=\"label\">(\ube44)<\/span><\/span><\/p>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">A. \ub8e8, H. \uc6b0<\/div>\n<div id=\"ref-id-sbref49\" class=\"title text-m\">\uc5fc\uc99d\ubcf5\ud569\uccb4\uc758 \uad6c\uc870\uc801 \uba54\ucee4\ub2c8\uc998<\/div>\n<\/div>\n<div class=\"host u-font-sans\">FEBS J., 282(3)(2015), 435-444\ud398\uc774\uc9c0<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/doi.org\/10.1111\/febs.13133\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref49\"><span class=\"anchor-text\">CrossRef<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84921730204&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref49\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Structural%20mechanisms%20of%20inflammasomeassembly&amp;publication_year=2015&amp;author=A.%20Lu&amp;author=H.%20Wu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref49\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib51\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib51\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[51]<\/span><\/a><\/span><span class=\"reference\"><span class=\"label\">(\u314f)<\/span><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">VA \ub77c\ud2f0\ub0a8, KA \ud53c\uce20\uc81c\ub7f4\ub4dc<\/div>\n<div id=\"ref-id-sbref50\" class=\"title text-m\">\uc5fc\uc99d\ubcf5\ud569\uccb4: \uc0c8\ub85c\uc6b4 \uba54\ucee4\ub2c8\uc998\uacfc \ud6a8\uacfc\uae30 \uae30\ub2a5<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc138\ud3ec, 165(4)(2016), pp. 792-800<\/div>\n<div class=\"comment\">7<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0092867416303440\/pdfft?md5=029f647d7c5612e240820101cd1062c1&amp;pid=1-s2.0-S0092867416303440-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref50\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0092867416303440\" aria-describedby=\"ref-id-sbref50\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84965107840&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref50\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Inflammasome%20complexes%3A%20emerging%20mechanisms%20and%20effector%20functions&amp;publication_year=2016&amp;author=V.A.%20Rathinam&amp;author=K.A.%20Fitzgerald\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref50\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<p><span class=\"reference\"><span class=\"label\">(\ube44)<\/span><\/span><\/p>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Q. \uc120, MJ \uc2a4\uce87<\/div>\n<div id=\"ref-id-sbref51\" class=\"title text-m\">\ub2e4\uae30\ub2a5 \uc5fc\uc99d \ub9e4\uac1c\uccb4\ub85c\uc11c\uc758 \uce74\uc2a4\ud30c\uc81c-1: \ube44\uc0ac\uc774\ud1a0\uce74\uc778 \uc131\uc219 \uc5ed\ud560<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. Leukoc. Biol., 100(5)(2016), pp. 961-967<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84994099379&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref51\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Caspase-1%20as%20a%20multifunctional%20inflammatory%20mediator%3A%20noncytokine%20maturation%20roles&amp;publication_year=2016&amp;author=Q.%20Sun&amp;author=M.J.%20Scott\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref51\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib52\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib52\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[52]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Z. \ub9ac, J. \uad6c\uc624, L. \ube44<\/div>\n<div id=\"ref-id-sbref52\" class=\"title text-m\">\uc790\uac00\uba74\uc5ed \uc9c8\ud658\uc5d0\uc11c NLRP3 \uc778\ud50c\ub77c\ub9c8\uc19c\uc758 \uc5ed\ud560<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ubc14\uc774\uc624\uba54\ub4dc. Pharm., 130 (2020), \uc870\ud56d 110542,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.biopha.2020.110542\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.biopha.2020.110542<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332220307356\/pdfft?md5=0716bf286fdf61f04cf818aa7a91a333&amp;pid=1-s2.0-S0753332220307356-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref52\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332220307356\" aria-describedby=\"ref-id-sbref52\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85088642878&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref52\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Role%20of%20the%20NLRP3%20inflammasome%20in%20autoimmune%20diseases&amp;publication_year=2020&amp;author=Z.%20Li&amp;author=J.%20Guo&amp;author=L.%20Bi\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref52\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib53\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib53\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[53]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">SM \ub9e8, TD \uce74\ub124\uac04\ud2f0<\/div>\n<div id=\"ref-id-sbref53\" class=\"title text-m\">\uc5fc\uc99d\ubcf5\ud569\uccb4 \ud65c\uc131\ud654 \uc870\uc808<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uba74\uc5ed. Rev., 265(1)(2015), pp. 6-21,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1111\/imr.12296\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1111\/imr.12296<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84927732725&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref53\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Regulation%20of%20inflammasome%20activation&amp;publication_year=2015&amp;author=S.M.%20Man&amp;author=T.D.%20Kanneganti\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref53\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib54\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib54\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[54]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">G. \ub85c\ud398\uc988-\uce74\uc2a4\ud14c\ud63c<\/div>\n<div id=\"ref-id-sbref54\" class=\"title text-m\">\uc720\ube44\ud034\ud2f4 \uc2dc\uc2a4\ud15c\uc5d0 \uc758\ud55c \uc778\ud50c\ub77c\ub9c8\uc19c \uc81c\uc5b4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">FEBS J., 287 (1) (2020), 11-26 \ud398\uc774\uc9c0,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1111\/febs.15118\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1111\/febs.15118<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85075213212&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref54\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Control%20of%20the%20inflammasome%20by%20the%20ubiquitin%20system&amp;publication_year=2020&amp;author=G.%20Lopez-Castejon\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref54\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib55\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib55\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[55]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">A. Mathur, JA \ud5e4\uc774\uc6cc\ub4dc, SM \ub9e8<\/div>\n<div id=\"ref-id-sbref55\" class=\"title text-m\">\uc5fc\uc99d\ubcf5\ud569\uccb4 \uc2e0\ud638 \uc804\ub2ec\uc758 \ubd84\uc790 \uba54\ucee4\ub2c8\uc998<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. Leukoc. Biol., 103(2)(2018), pp. 233-257,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1189\/jlb.3MR0617-250R\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1189\/jlb.3MR0617-250R<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85040982442&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref55\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Molecular%20mechanisms%20of%20inflammasome%20signaling&amp;publication_year=2018&amp;author=A.%20Mathur&amp;author=J.A.%20Hayward&amp;author=S.M.%20Man\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref55\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib56\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib56\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[56]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">R. \ub370\uc774 \uc0ac\ub974\uce74\ub974, S. \uc2e0\ud558, N. \ube44\uc2a4\uc640\uc2a4<\/div>\n<div id=\"ref-id-sbref56\" class=\"title text-m\">\uc778\ud50c\ub77c\ub9c8\uc19c\uc758 \uc870\uc791: \ud3d0\uc554\uc758 \uba74\uc5ed\uc694\ubc95\uc5d0 \ub300\ud55c \uc720\ub9dd\ud55c \uc811\uadfc\ubc95<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Int Rev. Immunol., 40 (3) (2021), pp. 171-182,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1080\/08830185.2021.1876044\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1080\/08830185.2021.1876044<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85100156585&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref56\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Manipulation%20of%20inflammasome%3A%20a%20promising%20approach%20towards%20immunotherapy%20of%20lung%20cancer&amp;publication_year=2021&amp;author=R.%20Dey%20Sarkar&amp;author=S.%20Sinha&amp;author=N.%20Biswas\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref56\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib57\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib57\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[57]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Y. Qu, S. Misaghi, K. Newton, LL Gilmour, S. Louie, JE Cupp, GR Dubyak, D. Hackos, VM Dixit<\/div>\n<div id=\"ref-id-sbref57\" class=\"title text-m\">Pannexin-1\uc740 \uc138\ud3ec\uc0ac\uba78 \uc911 ATP \ubc29\ucd9c\uc5d0 \ud544\uc694\ud558\uc9c0\ub9cc \uc5fc\uc99d\ubcf5\ud569\uccb4 \ud65c\uc131\ud654\uc5d0\ub294 \ud544\uc694\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. Immunol., 186(11)(2011), pp. 6553-6561,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.4049\/jimmunol.1100478\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.4049\/jimunol.1100478<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-79958034097&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref57\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Pannexin-1%20is%20required%20for%20ATP%20release%20during%20apoptosis%20but%20not%20for%20inflammasome%20activation&amp;publication_year=2011&amp;author=Y.%20Qu&amp;author=S.%20Misaghi&amp;author=K.%20Newton&amp;author=L.L.%20Gilmour&amp;author=S.%20Louie&amp;author=J.E.%20Cupp&amp;author=G.R.%20Dubyak&amp;author=D.%20Hackos&amp;author=V.M.%20Dixit\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref57\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib58\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib58\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[58]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">N. \ucf08\ub9ac, D. \uc824\ud14c\ub9c8, Y. \ub450\uc548, Y. \uadf8<\/div>\n<div id=\"ref-id-sbref58\" class=\"title text-m\">NLRP3 \uc778\ud50c\ub77c\ub9c8\uc19c: \ud65c\uc131\ud654 \ubc0f \uc870\uc808 \uba54\ucee4\ub2c8\uc998 \uac1c\uc694<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Int J. Mol. Sci., 20(13)(2019), p. 3328,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.3390\/ijms20133328\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.3390\/ijms20133328<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85069291313&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref58\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20NLRP3%20Inflammasome%3A%20An%20Overview%20of%20Mechanisms%20of%20Activation%20and%20Regulation&amp;publication_year=2019&amp;author=N.%20Kelley&amp;author=D.%20Jeltema&amp;author=Y.%20Duan&amp;author=Y.%20He\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref58\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib59\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib59\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[59]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">X. Fang, Y. Wang, Y. Zhang, Y. Li, J. Kwak-Kim, L. Wu<\/div>\n<div id=\"ref-id-sbref59\" class=\"title text-m\">NLRP3 \uc778\ud50c\ub77c\ub9c8\uc19c\uacfc \ubd80\uc778\uacfc \uc9c8\ud658 \ubc0f \uc0b0\uacfc \ud569\ubcd1\uc99d\uc5d0\uc11c\uc758 \uc911\uc694\ud55c \uc5ed\ud560<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Front Immunol., 11 (2021), \uc870\ud56d 555826,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.3389\/fimmu.2020.555826\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.3389\/fimmu.2020.555826<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=NLRP3%20Inflammasome%20and%20Its%20Critical%20Role%20in%20Gynecological%20Disorders%20and%20Obstetrical%20Complications&amp;publication_year=2021&amp;author=X.%20Fang&amp;author=Y.%20Wang&amp;author=Y.%20Zhang&amp;author=Y.%20Li&amp;author=J.%20Kwak-Kim&amp;author=L.%20Wu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref59\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib60\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib60\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[60]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Y. \ub8e8\uc624, C. \ub808\uc774\uc2a4, S. \uccb8<\/div>\n<div id=\"ref-id-sbref60\" class=\"title text-m\">\ucd9c\ud608\uc131 \ub1cc\uc878\uc911\uc758 \ubcd1\ud0dc\uc0dd\ub9ac\uc5d0 \ub300\ud55c NLRP3 \uc778\ud50c\ub77c\ub9c8\uc19c: \uac80\ud1a0<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud604\uc7ac Neuropharmacol., 17 (7) (2019), pp. 582-589,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.2174\/1570159X17666181227170053\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.2174\/1570159X17666181227170053<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85069214237&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref60\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=NLRP3%20Inflammasome%20in%20the%20Pathophysiology%20of%20Hemorrhagic%20Stroke%3A%20A%20Review&amp;publication_year=2019&amp;author=Y.%20Luo&amp;author=C.%20Reis&amp;author=S.%20Chen\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref60\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib61\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib61\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[61]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Z. Liu, C. Wang, J. Yang, Y. Chen, B. Zhou, DW Abbott, TS Xiao<\/div>\n<div id=\"ref-id-sbref61\" class=\"title text-m\">Caspase-1\uc740 Caspase \ubaa8\uc9d1 \ubc0f \uae30\uc9c8 \uc808\ub2e8\uc744 \uc911\uc7ac\ud558\ub294 \ub450 \uac00\uc9c0 \uace0\uc720\ud55c \uc778\ud130\ud398\uc774\uc2a4\ub97c \ud1b5\ud574 \uc804\uccb4 \uae38\uc774\uc758 Gasdermin D\ub97c \uc0ac\uc6a9\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"comment\">e5<\/div>\n<div class=\"host u-font-sans\">\uba74\uc5ed, 53 (1) (2020), pp. 106-114,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.immuni.2020.06.007\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.immuni.2020.06.007<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Caspase-1%20Engages%20Full-Length%20Gasdermin%20D%20through%20Two%20Distinct%20Interfaces%20That%20Mediate%20Caspase%20Recruitment%20and%20Substrate%20Cleavage&amp;publication_year=2020&amp;author=Z.%20Liu&amp;author=C.%20Wang&amp;author=J.%20Yang&amp;author=Y.%20Chen&amp;author=B.%20Zhou&amp;author=D.W.%20Abbott&amp;author=T.S.%20Xiao\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref61\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib62\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib62\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[62]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">CW Davies, I. Stowe, QT Phung, H. Ho, CE Bakalarski, A. Gupta, Y. Zhang, JR Lill, J. Payandeh, N. Kayagaki, JT Koerber<\/div>\n<div id=\"ref-id-sbref62\" class=\"title text-m\">\uce74\uc2a4\ud30c\uc81c \uc808\ub2e8 \ubaa8\ud2f0\ud504 \ud56d\uccb4\uc758 \ubc1c\uacac\uc73c\ub85c \ube44\uc815\uaddc\uc801\uc778 \uc5fc\uc99d\ubcf5\ud569\uccb4 \uae30\ub2a5\uc5d0 \ub300\ud55c \ud1b5\ucc30\ub825 \ubc1d\ud600<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc9c4\ud589 Natl. Acad. \uacfc\ud559. \ubbf8\uad6d, 118 (12) (2021), \uc870\ud56d e2018024118,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1073\/pnas.2018024118\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1073\/pnas.2018024118<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85102705479&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref62\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Discovery%20of%20a%20caspase%20cleavage%20motif%20antibody%20reveals%20insights%20into%20noncanonical%20inflammasome%20function&amp;publication_year=2021&amp;author=C.W.%20Davies&amp;author=I.%20Stowe&amp;author=Q.T.%20Phung&amp;author=H.%20Ho&amp;author=C.E.%20Bakalarski&amp;author=A.%20Gupta&amp;author=Y.%20Zhang&amp;author=J.R.%20Lill&amp;author=J.%20Payandeh&amp;author=N.%20Kayagaki&amp;author=J.T.%20Koerber\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref62\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib63\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib63\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[63]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">S. Matikainen, TA Nyman, W. Cypryk<\/div>\n<div id=\"ref-id-sbref63\" class=\"title text-m\">\ube44\uc815\uaddc \uce74\uc2a4\ud30c\uc81c-4\/5\/11 \uc778\ud50c\ub77c\ub9c8\uc19c\uc758 \uae30\ub2a5 \ubc0f \uc870\uc808<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. Immunol., 204(12)(2020), pp. 3063-3069,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.4049\/jimmunol.2000373\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.4049\/jimunol.2000373<\/span><\/a><\/div>\n<div class=\"comment\">PMID: 32513874<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85086298206&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref63\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Function%20and%20Regulation%20of%20Noncanonical%20Caspase-4511%20Inflammasome&amp;publication_year=2020&amp;author=S.%20Matikainen&amp;author=T.A.%20Nyman&amp;author=W.%20Cypryk\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref63\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib64\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib64\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[64]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">CW Davies, I. Stowe, QT Phung, H. Ho, CE Bakalarski, A. Gupta, Y. Zhang, JR Lill, J. Payandeh, N. Kayagaki, JT Koerber<\/div>\n<div id=\"ref-id-sbref64\" class=\"title text-m\">\uce74\uc2a4\ud30c\uc81c \uc808\ub2e8 \ubaa8\ud2f0\ud504 \ud56d\uccb4\uc758 \ubc1c\uacac\uc73c\ub85c \ube44\uc815\uaddc\uc801\uc778 \uc5fc\uc99d\ubcf5\ud569\uccb4 \uae30\ub2a5\uc5d0 \ub300\ud55c \ud1b5\ucc30\ub825 \ubc1d\ud600<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc9c4\ud589 Natl. Acad. \uacfc\ud559. \ubbf8\uad6d, 118 (12) (2021), \uc870\ud56d e2018024118,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1073\/pnas.2018024118\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1073\/pnas.2018024118<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85102705479&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref64\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Discovery%20of%20a%20caspase%20cleavage%20motif%20antibody%20reveals%20insights%20into%20noncanonical%20inflammasome%20function&amp;publication_year=2021&amp;author=C.W.%20Davies&amp;author=I.%20Stowe&amp;author=Q.T.%20Phung&amp;author=H.%20Ho&amp;author=C.E.%20Bakalarski&amp;author=A.%20Gupta&amp;author=Y.%20Zhang&amp;author=J.R.%20Lill&amp;author=J.%20Payandeh&amp;author=N.%20Kayagaki&amp;author=J.T.%20Koerber\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref64\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib65\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib65\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[65]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">SS Wright, SO Vasudevan, VA Rathinam<\/div>\n<div id=\"ref-id-sbref65\" class=\"title text-m\">\ube44\uc815\uaddc\uc801 \uc5fc\uc99d\ubcf5\ud569\uccb4 \ub9e4\uac1c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\uc758 \uba54\ucee4\ub2c8\uc998 \ubc0f \uacb0\uacfc<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J.Mol. Biol., 434 (4) (2022), \uc870\ud56d 167245,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.jmb.2021.167245\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.jmb.2021.167245<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0022283621004782\/pdfft?md5=236e55331a6265140bf0ed6df029af1d&amp;pid=1-s2.0-S0022283621004782-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref65\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0022283621004782\" aria-describedby=\"ref-id-sbref65\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85115946858&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref65\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Mechanisms%20and%20consequences%20of%20noncanonical%20inflammasome-mediated%20pyroptosis&amp;publication_year=2022&amp;author=S.S.%20Wright&amp;author=S.O.%20Vasudevan&amp;author=V.A.%20Rathinam\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref65\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib66\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib66\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[66]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">D. Yang, Y. He, R. Mu\u00f1oz-Planillo, Q. Liu, G. N\u00fa\u00f1ez<\/div>\n<div id=\"ref-id-sbref66\" class=\"title text-m\">Caspase-11\uc740 Pyroptosis \ubc0f \ub0b4\ub3c5\uc131 \uc1fc\ud06c\ub97c \uc911\uc7ac\ud558\uae30 \uc704\ud574 Pannexin-1 \ucc44\ub110\uacfc Purinergic P2X7 Pore\uac00 \ud544\uc694\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uba74\uc5ed, 43 (5) (2015), pp. 923-932,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.immuni.2015.10.009\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.immuni.2015.10.009<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1074761315004094\/pdfft?md5=c72e71c08bd9f2b97894ca99659c6adf&amp;pid=1-s2.0-S1074761315004094-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref66\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1074761315004094\" aria-describedby=\"ref-id-sbref66\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84947441282&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref66\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Caspase-11%20Requires%20the%20Pannexin-1%20Channel%20and%20the%20Purinergic%20P2X7%20Pore%20to%20Mediate%20Pyroptosis%20and%20Endotoxic%20Shock&amp;publication_year=2015&amp;author=D.%20Yang&amp;author=Y.%20He&amp;author=R.%20Mu%C3%B1oz-Planillo&amp;author=Q.%20Liu&amp;author=G.%20N%C3%BA%C3%B1ez\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref66\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib67\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib67\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[67]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">F. Humphries, L. Shmuel-Galia, N. Ketelut-Carneiro, S. Li, B. Wang, VV Nemmara, R. Wilson, Z. Jiang, F. Khalighinejad, K. Muneeruddin, SA Shaffer, R. Dutta, C. Ionete, S. Pesiridis, S. Yang, PR Thompson, KA Fitzgerald<\/div>\n<div id=\"ref-id-sbref67\" class=\"title text-m\">\uc11d\uc2e0\ud654\ub294 \uac00\uc2a4\ub354\ubbfc D\ub97c \ube44\ud65c\uc131\ud654\ud558\uace0 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \ucc28\ub2e8\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uacfc\ud559, 369 (6511) (2020), pp. 1633-1637,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1126\/science.abb9818\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1126\/science.abb9818<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Succination%20inactivates%20gasdermin%20D%20and%20blocks%20pyroptosis&amp;publication_year=2020&amp;author=F.%20Humphries&amp;author=L.%20Shmuel-Galia&amp;author=N.%20Ketelut-Carneiro&amp;author=S.%20Li&amp;author=B.%20Wang&amp;author=V.V.%20Nemmara&amp;author=R.%20Wilson&amp;author=Z.%20Jiang&amp;author=F.%20Khalighinejad&amp;author=K.%20Muneeruddin&amp;author=S.A.%20Shaffer&amp;author=R.%20Dutta&amp;author=C.%20Ionete&amp;author=S.%20Pesiridis&amp;author=S.%20Yang&amp;author=P.R.%20Thompson&amp;author=K.A.%20Fitzgerald\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref67\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib68\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib68\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[68]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">BE Burdette, AN Esparza, H. Zhu, S. Wang<\/div>\n<div id=\"ref-id-sbref68\" class=\"title text-m\">\ubc1c\uc5f4\uc99d\uc758 \uac00\uc2a4\ub354\ubbfc D<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc561\ud0c0\ud31c. \uc8c4. B., 11(9)(2021), pp. 2768-2782,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.apsb.2021.02.006\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.apsb.2021.02.006<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2211383521000447\/pdfft?md5=63a7193aba1e6361ac3240a8200d18a5&amp;pid=1-s2.0-S2211383521000447-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref68\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2211383521000447\" aria-describedby=\"ref-id-sbref68\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85111499098&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref68\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Gasdermin%20D%20in%20pyroptosis&amp;publication_year=2021&amp;author=B.E.%20Burdette&amp;author=A.N.%20Esparza&amp;author=H.%20Zhu&amp;author=S.%20Wang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref68\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib69\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib69\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[69]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">N. Kayagaki, IB Stowe, BL Lee, K. O&#039;Rourke, K. Anderson, S. Warming, T. Cuellar, B. Haley, M. Roose-Girma, QT Phung, PS Liu, JR Lill, H. Li , J. Wu, S. Kummerfeld, J. Zhang, WP Lee, SJ Snipas, GS Salvesen, LX Morris, L. Fitzgerald, Y. Zhang, EM Bertram, CC Goodnow, VM Dixit<\/div>\n<div id=\"ref-id-sbref69\" class=\"title text-m\">Caspase-11\uc740 \ube44\ud45c\uc900 \uc5fc\uc99d\ubcf5\ud569\uccb4 \uc2e0\ud638 \uc804\ub2ec\uc744 \uc704\ud574 \uac00\uc2a4\ub354\ubbfc D\ub97c \uc808\ub2e8\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc790\uc5f0, 526 (7575) (2015), pp. 666-671,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1038\/nature15541\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1038\/\uc790\uc5f015541<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84942856523&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref69\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Caspase-11%20cleaves%20gasdermin%20D%20for%20non-canonical%20inflammasome%20signalling&amp;publication_year=2015&amp;author=N.%20Kayagaki&amp;author=I.B.%20Stowe&amp;author=B.L.%20Lee&amp;author=K.%20O%27Rourke&amp;author=K.%20Anderson&amp;author=S.%20Warming&amp;author=T.%20Cuellar&amp;author=B.%20Haley&amp;author=M.%20Roose-Girma&amp;author=Q.T.%20Phung&amp;author=P.S.%20Liu&amp;author=J.R.%20Lill&amp;author=H.%20Li&amp;author=J.%20Wu&amp;author=S.%20Kummerfeld&amp;author=J.%20Zhang&amp;author=W.P.%20Lee&amp;author=S.J.%20Snipas&amp;author=G.S.%20Salvesen&amp;author=L.X.%20Morris&amp;author=L.%20Fitzgerald&amp;author=Y.%20Zhang&amp;author=E.M.%20Bertram&amp;author=C.C.%20Goodnow&amp;author=V.M.%20Dixit\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref69\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib70\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib70\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[70]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">X. Liu, Z. Zhang, J. Ruan, Y. Pan, VG Magupalli, H. Wu, J. Lieberman<\/div>\n<div id=\"ref-id-sbref70\" class=\"title text-m\">Inflammasome \ud65c\uc131\ud654 gasdermin D\ub294 \ub9c9 \uad6c\uba4d\uc744 \ud615\uc131\ud558\uc5ec pyroptosis\ub97c \uc720\ubc1c\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc790\uc5f0, 535 (7610) (2016), pp. 153-158,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1038\/nature18629\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1038\/\uc790\uc5f018629<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Inflammasome-activated%20gasdermin%20D%20causes%20pyroptosis%20by%20forming%20membrane%20pores&amp;publication_year=2016&amp;author=X.%20Liu&amp;author=Z.%20Zhang&amp;author=J.%20Ruan&amp;author=Y.%20Pan&amp;author=V.G.%20Magupalli&amp;author=H.%20Wu&amp;author=J.%20Lieberman\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref70\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib71\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib71\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[71]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">J. \uc2dc, W. \uac00\uc624, F. \uc0e4\uc624<\/div>\n<div id=\"ref-id-sbref71\" class=\"title text-m\">\ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4: \uac00\uc2a4\ub354\ubbfc \ub9e4\uac1c \ud504\ub85c\uadf8\ub7a8\ub41c \uad34\uc0ac\uc131 \uc138\ud3ec \uc0ac\uba78<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Trends Biochem Sci., 42 (4) (2017), pp. 245-254,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.tibs.2016.10.004\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.tibs.2016.10.004<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0968000416301827\/pdfft?md5=78b194c8f2c41e414a54a46eab39f285&amp;pid=1-s2.0-S0968000416301827-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref71\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0968000416301827\" aria-describedby=\"ref-id-sbref71\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85007439966&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref71\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Pyroptosis%3A%20gasdermin-mediated%20programmed%20necrotic%20cell%20death&amp;publication_year=2017&amp;author=J.%20Shi&amp;author=W.%20Gao&amp;author=F.%20Shao\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref71\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib72\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib72\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[72]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">L. \uc2a4\ubcf4\ub9ac\uc9c0, S. \ub8f0, E. \uba40\ube44\ud790,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref72\" class=\"title text-m\">GSDMD \ub9c9 \uae30\uacf5 \ud615\ud0dc -Tion\uc740 pyroptotic \uc138\ud3ec \uc0ac\uba78\uc758 \uba54\ucee4\ub2c8\uc998\uc744 \uad6c\uc131\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">EMBO J., 35(16)(2016), pp. 1766-1778<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=GSDMD%20membrane%20pore%20forma-Tion%20constitutes%20the%20mechanism%20of%20pyroptotic%20cell%20death&amp;publication_year=2016&amp;author=L.%20Sborigi&amp;author=S.%20Ruhl&amp;author=E.%20Mulvihill\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref72\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib73\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib73\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[73]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">RA Aglietti, EC \ub4c0\ubc84<\/div>\n<div id=\"ref-id-sbref73\" class=\"title text-m\">pyroptosis \ubc0f gasderminfamily \uae30\ub2a5\uc758 \uae30\ubcf8 \ubd84\uc790 \uba54\ucee4\ub2c8\uc998\uc5d0 \ub300\ud55c \ucd5c\uadfc \ud1b5\ucc30\ub825<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Trends Immunol., 38(2017), pp. 261-271<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1471490617300157\/pdfft?md5=f95b8736800881afc126ac16c8541dc7&amp;pid=1-s2.0-S1471490617300157-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref73\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1471490617300157\" aria-describedby=\"ref-id-sbref73\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85012024592&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref73\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Recent%20insights%20into%20the%20molecularmechanisms%20underlying%20pyroptosis%20and%20gasderminfamily%20functions&amp;publication_year=2017&amp;author=R.A.%20Aglietti&amp;author=E.C.%20Dueber\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref73\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib74\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib74\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[74]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">W. \uc655, T. \uc7a5<\/div>\n<div id=\"ref-id-sbref74\" class=\"title text-m\">CD T \uc138\ud3ec \uc0ac\uba78\uc744 \ucd09\uc9c4\ud558\ub294 Caspase-1 \ub9e4\uac1c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4: \ube44\uad6d\uc18c\uc801 \uacf5\uac04 \uc218\ud559\uc801 \ubaa8\ub378 J<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud669\uc18c. \uc218\ud559. Biol., 80(3)(2018), pp. 540-582,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1007\/s11538-017-0389-8\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1007\/s11538-017-0389-8<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85040788125&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref74\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Caspase-1-mediated%20pyroptosis%20of%20the%20predominance%20for%20driving%20CD%20T%20cells%20death%3A%20a%20nonlocal%20spatial%20mathematical%20model%20J&amp;publication_year=2018&amp;author=W.%20Wang&amp;author=T.%20Zhang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref74\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib75\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib75\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[75]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">D. He, J. Zheng, J. Hu, J. Chen, X. \uc6e8\uc774<\/div>\n<div id=\"ref-id-sbref75\" class=\"title text-m\">\uae34 \ube44\ucf54\ub529 RNA \ubc0f \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud074\ub9b0. \uce68. Acta, 504(2020), 201-208\ud398\uc774\uc9c0,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.cca.2019.11.035\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.cca.2019.11.035<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0009898119321576\/pdfft?md5=989078f36db6fdea8e53cfd34697fc53&amp;pid=1-s2.0-S0009898119321576-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref75\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0009898119321576\" aria-describedby=\"ref-id-sbref75\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85076245257&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref75\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Long%20non-coding%20RNAs%20and%20pyroptosis&amp;publication_year=2020&amp;author=D.%20He&amp;author=J.%20Zheng&amp;author=J.%20Hu&amp;author=J.%20Chen&amp;author=X.%20Wei\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref75\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib76\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib76\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[76]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">W. \uc7a5, W. Xu, Y. Feng, X. Zhou<\/div>\n<div id=\"ref-id-sbref76\" class=\"title text-m\">\ub2f9\ub1e8\ubcd1 \uc131 \uc2ec\uadfc \ubcd1\uc99d\uc758 \ubc1c\ubcd1 \uae30\uc804\uc5d0\uc11c \ube44 \ucf54\ub529 RNA \uad00\ub828<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. \uc138\ud3ec \ubab0. Med, 23(9)(2019), pp. 5859-5867,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1111\/jcmm.14510\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1111\/jcmm.14510<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85071432592&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref76\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Non-coding%20RNA%20involvement%20in%20the%20pathogenesis%20of%20diabetic%20cardiomyopathy&amp;publication_year=2019&amp;author=W.%20Zhang&amp;author=W.%20Xu&amp;author=Y.%20Feng&amp;author=X.%20Zhou\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref76\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib77\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib77\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[77]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">M. Cesana, D. Cacchiarelli, I. Legnini, T. Santini, O. Sthandier, M. Chinappi, A. Tramontano, I. Bozzoni<\/div>\n<div id=\"ref-id-sbref77\" class=\"title text-m\">\uae34 \ube44\uc554\ud638\ud654 RNA\ub294 \uacbd\uc7c1\ud558\ub294 \ub0b4\uc778\uc131 RNA\ub85c \uae30\ub2a5\ud558\uc5ec \uadfc\uc721 \ubd84\ud654\ub97c \uc81c\uc5b4\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc140, 147(2)(2011), pp. 358-369,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.cell.2011.09.028\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.cell.2011.09.028<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0092867411011391\/pdfft?md5=c8af40269849860454ef06147b653411&amp;pid=1-s2.0-S0092867411011391-mainext.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref77\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0092867411011391\" aria-describedby=\"ref-id-sbref77\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-80054715378&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref77\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=A%20long%20noncoding%20RNA%20controls%20muscle%20differentiation%20by%20functioning%20as%20a%20competing%20endogenous%20RNA&amp;publication_year=2011&amp;author=M.%20Cesana&amp;author=D.%20Cacchiarelli&amp;author=I.%20Legnini&amp;author=T.%20Santini&amp;author=O.%20Sthandier&amp;author=M.%20Chinappi&amp;author=A.%20Tramontano&amp;author=I.%20Bozzoni\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref77\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib78\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib78\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[78]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">P. Wan, W. Su, Y. Zhang, Z. Li, C. Deng, J. Li, N. Jiang, S. Huang, E. Long, Y. Zhuo<\/div>\n<div id=\"ref-id-sbref78\" class=\"title text-m\">LncRNA H19\ub294 \ub9dd\ub9c9 \ud5c8\ud608 \/ \uc7ac\uad00\ub958 \uc190\uc0c1\uc5d0\uc11c \uc18c\uad50 \uc138\ud3ec \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \ubc0f \uc2e0\uacbd \uc138\ud3ec \uc0ac\uba78\uc744 \uc2dc\uc791\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Cell Death Different., 27 (1) (2020), pp. 176-191,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1038\/s41418-019-0351-4\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1038\/s41418-019-0351-4<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85066260765&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref78\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=LncRNA%20H19%20initiates%20microglial%20pyroptosis%20and%20neuronal%20death%20in%20retinal%20ischemiareperfusion%20injury&amp;publication_year=2020&amp;author=P.%20Wan&amp;author=W.%20Su&amp;author=Y.%20Zhang&amp;author=Z.%20Li&amp;author=C.%20Deng&amp;author=J.%20Li&amp;author=N.%20Jiang&amp;author=S.%20Huang&amp;author=E.%20Long&amp;author=Y.%20Zhuo\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref78\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib79\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib79\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[79]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">W. Chi, F. Li, H. Chen, Y. Wang, Y. Zhu, X. Yang, J. Zhu, F. Wu, H. Ouyang, J. Ge, RN Weinreb, K. Zhang, Y. Zhuo<\/div>\n<div id=\"ref-id-sbref79\" class=\"title text-m\">Caspase-8\uc740 \uae09\uc131 \ub179\ub0b4\uc7a5\uc5d0\uc11c NLRP1\/NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4 \ud65c\uc131\ud654 \ubc0f IL-1\u03b2 \uc0dd\uc0b0\uc744 \ucd09\uc9c4\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc9c4\ud589 Natl. Acad. \uacfc\ud559. \ubbf8\uad6d, 111 (30) (2014), pp. 11181-11186,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1073\/pnas.1402819111\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1073\/pnas.1402819111<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84904990668&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref79\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Caspase-8%20promotes%20NLRP1NLRP3%20inflammasome%20activation%20and%20IL-1%20production%20in%20acute%20glaucoma&amp;publication_year=2014&amp;author=W.%20Chi&amp;author=F.%20Li&amp;author=H.%20Chen&amp;author=Y.%20Wang&amp;author=Y.%20Zhu&amp;author=X.%20Yang&amp;author=J.%20Zhu&amp;author=F.%20Wu&amp;author=H.%20Ouyang&amp;author=J.%20Ge&amp;author=R.N.%20Weinreb&amp;author=K.%20Zhang&amp;author=Y.%20Zhuo\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref79\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib80\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib80\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[80]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">A. Keniry, D. Oxley, P. Monnier, M. Kyba, L. Dandolo, G. Smits, W. Reik<\/div>\n<div id=\"ref-id-sbref80\" class=\"title text-m\">H19 lincRNA\ub294 \uc131\uc7a5\uacfc Igf1r\uc744 \uc5b5\uc81c\ud558\ub294 miR-675\uc758 \ubc1c\ub2ec \uc800\uc7a5\uc18c\uc785\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Nat. Cell Biol., 14(7)(2012), pp. 659-665,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1038\/ncb2521\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1038\/ncb2521<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84863219731&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref80\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20H19%20lincRNA%20is%20a%20developmental%20reservoir%20of%20miR-675%20that%20suppresses%20growth%20and%20Igf1r&amp;publication_year=2012&amp;author=A.%20Keniry&amp;author=D.%20Oxley&amp;author=P.%20Monnier&amp;author=M.%20Kyba&amp;author=L.%20Dandolo&amp;author=G.%20Smits&amp;author=W.%20Reik\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref80\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib81\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib81\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[81]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">DY Li, A. Busch, H. Jin, E. Chernogubova, J. Pelisek, J. Karlsson, B. Sennblad, S. Liu, S. Lao, P. Hofmann, A. B\u00e4cklund, SM Eken, J. Roy, P. Eriksson, B. Dacken, D. Ramanujam, A. Dueck, S. Engelhardt, RA Boon, HH Eckstein, JM Spin, PS Tsao, L. Maegdefessel<\/div>\n<div id=\"ref-id-sbref81\" class=\"title text-m\">H19\ub294 \ubcf5\ubd80 \ub300\ub3d9\ub9e5\ub958 \ubc1c\uc0dd \ubc0f \uc9c4\ud589\uc744 \uc720\ub3c4\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc21c\ud658, 138 (15) (2018), pp. 1551-1568,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.117.032184\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1161\/CIRCULATIONAHA.117.032184<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85055184587&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref81\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=H19%20Induces%20Abdominal%20Aortic%20Aneurysm%20Development%20and%20Progression&amp;publication_year=2018&amp;author=D.Y.%20Li&amp;author=A.%20Busch&amp;author=H.%20Jin&amp;author=E.%20Chernogubova&amp;author=J.%20Pelisek&amp;author=J.%20Karlsson&amp;author=B.%20Sennblad&amp;author=S.%20Liu&amp;author=S.%20Lao&amp;author=P.%20Hofmann&amp;author=A.%20B%C3%A4cklund&amp;author=S.M.%20Eken&amp;author=J.%20Roy&amp;author=P.%20Eriksson&amp;author=B.%20Dacken&amp;author=D.%20Ramanujam&amp;author=A.%20Dueck&amp;author=S.%20Engelhardt&amp;author=R.A.%20Boon&amp;author=H.H.%20Eckstein&amp;author=J.M.%20Spin&amp;author=P.S.%20Tsao&amp;author=L.%20Maegdefessel\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref81\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib82\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib82\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[82]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">WH Zhang, X. Wang, M. Narayanan, Y. Zhang, C. Huo, JC Reed, RM Friedlander<\/div>\n<div id=\"ref-id-sbref82\" class=\"title text-m\">\uc800\uc0b0\uc18c\uc99d \ubc0f \ud5c8\ud608 \uc720\ubc1c \uc2e0\uacbd \uc138\ud3ec \uc0ac\uba78\uc5d0\uc11c Rip2\/caspase-1 \uacbd\ub85c\uc758 \uae30\ubcf8 \uc5ed\ud560<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc9c4\ud589 Natl. Acad. \uacfc\ud559. \ubbf8\uad6d, 100(26)(2003), pp. 16012-16017,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1073\/pnas.2534856100\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1073\/pnas.2534856100<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-0346103651&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref82\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Fundamental%20role%20of%20the%20Rip2caspase-1%20pathway%20in%20hypoxia%20and%20ischemia-induced%20neuronal%20cell%20death&amp;publication_year=2003&amp;author=W.H.%20Zhang&amp;author=X.%20Wang&amp;author=M.%20Narayanan&amp;author=Y.%20Zhang&amp;author=C.%20Huo&amp;author=J.C.%20Reed&amp;author=R.M.%20Friedlander\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref82\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib83\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib83\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[83]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">QZ Tuo, ST Zhang, P. \ub808\uc774<\/div>\n<div id=\"ref-id-sbref83\" class=\"title text-m\">\ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc758 \uc2e0\uacbd\uc138\ud3ec \uc0ac\uba78 \uae30\uc804\uacfc \uce58\ub8cc\uc801 \uc758\ubbf8<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Med Res Rev., 42 (1) (2022), pp. 259-305,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1002\/med.21817\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1002\/med.21817<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85105148790&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref83\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Mechanisms%20of%20neuronal%20cell%20death%20in%20ischemic%20stroke%20and%20their%20therapeutic%20implications&amp;publication_year=2022&amp;author=Q.Z.%20Tuo&amp;author=S.T.%20Zhang&amp;author=P.%20Lei\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref83\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib84\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib84\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[84]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">J. Liang, Q. Wang, JQ Li, T. Guo, D. Yu<\/div>\n<div id=\"ref-id-sbref84\" class=\"title text-m\">\uae34 \ube44\ucf54\ub529 RNA MEG3\ub294 miR-485\/AIM2 \ucd95\uc744 \ud45c\uc801\uc73c\ub85c \uc0bc\uc544 \ubc1c\uc5f4\uc99d\uc744 \uc99d\uac00\uc2dc\ucf1c \ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc744 \ucd09\uc9c4\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud2b9\uae09. Neurol., 325 (2020), \uc870\ud56d 113139,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.expneurol.2019.113139\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.expneurol.2019.113139<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0014488619302869\/pdfft?md5=c32009110f4a234e536f16bbd938c229&amp;pid=1-s2.0-S0014488619302869-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref84\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0014488619302869\" aria-describedby=\"ref-id-sbref84\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85076270980&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref84\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Long%20non-coding%20RNA%20MEG3%20promotes%20cerebral%20ischemia-reperfusion%20injury%20through%20increasing%20pyroptosis%20by%20targeting%20miR-485AIM2%20axis&amp;publication_year=2020&amp;author=J.%20Liang&amp;author=Q.%20Wang&amp;author=J.Q.%20Li&amp;author=T.%20Guo&amp;author=D.%20Yu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref84\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib85\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib85\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[85]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">LQ Wang, YY Zheng, HJ Zhou, XX Zhang, P. Wu, SM Zhu<\/div>\n<div id=\"ref-id-sbref85\" class=\"title text-m\">LncRNA-Fendrr\ub294 HERC2\ub97c \ud1b5\ud574 NLRC4 \ub2e8\ubc31\uc9c8\uc758 \uc720\ube44\ud034\ud2f4\ud654 \ubc0f \ubd84\ud574\ub97c \ubc29\uc9c0\ud558\uc5ec \uc18c\uad50\uc138\ud3ec\uc758 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc870\uc808\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ubab0. Med, 27 (1) (2021), p. 39,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1186\/s10020-021-00299-y\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1186\/s10020-021-00299-y<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1008127520302352\/pdfft?md5=fb351049136416482400c5853e989211&amp;pid=1-s2.0-S1008127520302352-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref85\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1008127520302352\" aria-describedby=\"ref-id-sbref85\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=LncRNA-Fendrr%20protects%20against%20the%20ubiquitination%20and%20degradation%20of%20NLRC4%20protein%20through%20HERC2%20to%20regulate%20the%20pyroptosis%20of%20microglia&amp;publication_year=2021&amp;author=L.Q.%20Wang&amp;author=Y.Y.%20Zheng&amp;author=H.J.%20Zhou&amp;author=X.X.%20Zhang&amp;author=P.%20Wu&amp;author=S.M.%20Zhu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref85\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib86\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib86\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[86]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">HS Zhang, B. Ouyang, XY Ji, MF Liu<\/div>\n<div id=\"ref-id-sbref86\" class=\"title text-m\">Gastrodin\uc740 lncRNA NEAT1\/miR-22-3p \ucd95\uc744 \uc870\uc808\ud558\uc5ec Pyroptosis\ub97c \uc5b5\uc81c\ud558\uc5ec \ub1cc \ud5c8\ud608\/\uc7ac\uad00\ub958 \uc190\uc0c1\uc744 \uc644\ud654\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Neurochem Res, 46 (7) (2021), pp. 1747-1758,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1007\/s11064-021-03285-2\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1007\/s11064-021-03285-2<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85104117182&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref86\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Gastrodin%20Alleviates%20Cerebral%20IschaemiaReperfusion%20Injury%20by%20Inhibiting%20Pyroptosis%20by%20Regulating%20the%20lncRNA%20NEAT1miR-22-3p%20Axis&amp;publication_year=2021&amp;author=H.S.%20Zhang&amp;author=B.%20Ouyang&amp;author=X.Y.%20Ji&amp;author=M.F.%20Liu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref86\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib87\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib87\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[87]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Y. Ye, Z. Feng, S. Tian, Y. Yang, Y. Jia, G. Wang, J. Wang, W. Bai, J. Li, X. He<\/div>\n<div id=\"ref-id-sbref87\" class=\"title text-m\">HBO\ub294 lncRNA-H19\/miR-423-5p\/NLRP3 \ucd95\uc744 \ud1b5\ud574 \uc2e0\uacbd \uc904\uae30 \uc138\ud3ec \uc5f4\ubd84\ud574\uc99d\uc744 \uc644\ud654\ud558\uace0 \uc0b0\uc18c \ud3ec\ub3c4\ub2f9 \uacb0\ud54d \ud6c4 \uc2e0\uacbd \uc0dd\uc131\uc744 \uac1c\uc120\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc0b0\ud654\ubb3c. Med Cell Longev., 2022(2022), \uc870\ud56d 9030771,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1155\/2022\/9030771\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1155\/2022\/9030771<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85124775417&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref87\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=HBO%20Alleviates%20Neural%20Stem%20Cell%20Pyroptosis%20via%20lncRNA-H19miR-423-5pNLRP3%20Axis%20and%20Improves%20Neurogenesis%20after%20Oxygen%20Glucose%20Deprivation&amp;publication_year=2022&amp;author=Y.%20Ye&amp;author=Z.%20Feng&amp;author=S.%20Tian&amp;author=Y.%20Yang&amp;author=Y.%20Jia&amp;author=G.%20Wang&amp;author=J.%20Wang&amp;author=W.%20Bai&amp;author=J.%20Li&amp;author=X.%20He\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref87\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib88\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib88\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[88]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Z. Xue, Q. Xi, H. Liu, X. Guo, J. Zhang, Z. Zhang, Y. Li, G. Yang, D. Zhou, H. Yang, L. Zhang, Q. Zhang, C. Gu, J. Yang, Y. Da, Z. Yao, S. Duo, R. Zhang<\/div>\n<div id=\"ref-id-sbref88\" class=\"title text-m\">miR-21\uc740 NLRP3 inflammasome \ud65c\uc131\ud654\ub97c \ucd09\uc9c4\ud558\uc5ec \ubc1c\uc5f4\uc99d \ubc0f \ub0b4\ub3c5\uc18c \uc1fc\ud06c\ub97c \uc911\uc7ac\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc138\ud3ec \uc0ac\uba78 Dis., 10 (6) (2019), p. 461,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1038\/s41419-019-1713-z\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1038\/s41419-019-1713-z<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85067309759&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref88\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=miR-21%20promotes%20NLRP3%20inflammasome%20activation%20to%20mediate%20pyroptosis%20and%20endotoxic%20shock&amp;publication_year=2019&amp;author=Z.%20Xue&amp;author=Q.%20Xi&amp;author=H.%20Liu&amp;author=X.%20Guo&amp;author=J.%20Zhang&amp;author=Z.%20Zhang&amp;author=Y.%20Li&amp;author=G.%20Yang&amp;author=D.%20Zhou&amp;author=H.%20Yang&amp;author=L.%20Zhang&amp;author=Q.%20Zhang&amp;author=C.%20Gu&amp;author=J.%20Yang&amp;author=Y.%20Da&amp;author=Z.%20Yao&amp;author=S.%20Duo&amp;author=R.%20Zhang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref88\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib89\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib89\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[89]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">L. Vande Walle, N. Van Opdenbosch, P. Jacques, A. Fossoul, E. Verheugen, P. Vogel, R. Beyaert, D. Elewaut, TD Kanneganti, G. van Loo, M. Lamkanfi<\/div>\n<div id=\"ref-id-sbref89\" class=\"title text-m\">A20\uc5d0 \uc758\ud55c NLRP3 \uc778\ud50c\ub77c\ub9c8\uc19c\uc758 \uc74c\uc131 \uc870\uc808\uc740 \uad00\uc808\uc5fc\uc744 \uc608\ubc29\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc790\uc5f0, 512 (7512) (2014), pp. 69-73,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1038\/nature13322\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1038\/\uc790\uc5f013322<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Negative%20regulation%20of%20the%20NLRP3%20inflammasome%20by%20A20%20protects%20against%20arthritis&amp;publication_year=2014&amp;author=L.%20Vande%20Walle&amp;author=N.%20Van%20Opdenbosch&amp;author=P.%20Jacques&amp;author=A.%20Fossoul&amp;author=E.%20Verheugen&amp;author=P.%20Vogel&amp;author=R.%20Beyaert&amp;author=D.%20Elewaut&amp;author=T.D.%20Kanneganti&amp;author=G.%20van%20Loo&amp;author=M.%20Lamkanfi\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref89\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib90\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib90\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[90]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">J. Shi, Y. Zhao, K. Wang, X. Shi, Y. Wang, H. Huang, Y. Zhuang, T. Cai, F. Wang, F. Shao<\/div>\n<div id=\"ref-id-sbref90\" class=\"title text-m\">\uc5fc\uc99d\uc131 \uce74\uc2a4\ud30c\uc81c\uc5d0 \uc758\ud55c GSDMD\uc758 \uc808\ub2e8\uc740 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uc138\ud3ec \uc0ac\uba78\uc744 \uacb0\uc815\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc790\uc5f0, 526 (7575) (2015), pp. 660-665,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1038\/nature15514\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1038\/\uc790\uc5f015514<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84942892037&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref90\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Cleavage%20of%20GSDMD%20by%20inflammatory%20caspases%20determines%20pyroptotic%20cell%20death&amp;publication_year=2015&amp;author=J.%20Shi&amp;author=Y.%20Zhao&amp;author=K.%20Wang&amp;author=X.%20Shi&amp;author=Y.%20Wang&amp;author=H.%20Huang&amp;author=Y.%20Zhuang&amp;author=T.%20Cai&amp;author=F.%20Wang&amp;author=F.%20Shao\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref90\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib91\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib91\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[91]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">F. Yang, Y. Qin, Y. Wang, A. Li, J. Lv, X. Sun, H. Che, T. Han, S. Meng, Y. Bai, L. Wang<\/div>\n<div id=\"ref-id-sbref91\" class=\"title text-m\">LncRNA KCNQ1OT1\uc740 \ub2f9\ub1e8\ubcd1 \uc131 \uc2ec\uadfc \ubcd1\uc99d\uc5d0\uc11c \uc5f4\ud654\uc99d\uc744 \ub9e4\uac1c\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc138\ud3ec\ubb3c\ub9ac\ud559. Biochem, 50 (4) (2018), pp. 1230-1244,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1159\/000494576\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1159\/000494576<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85055668893&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref91\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=LncRNA%20KCNQ1OT1%20Mediates%20Pyroptosis%20in%20Diabetic%20Cardiomyopathy&amp;publication_year=2018&amp;author=F.%20Yang&amp;author=Y.%20Qin&amp;author=Y.%20Wang&amp;author=A.%20Li&amp;author=J.%20Lv&amp;author=X.%20Sun&amp;author=H.%20Che&amp;author=T.%20Han&amp;author=S.%20Meng&amp;author=Y.%20Bai&amp;author=L.%20Wang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref91\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib92\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib92\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[92]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">L. Galluzzi, I. Vitale, SA Aaronson, JM Abrams, D. Adam, P. Agostinis, ES Alnemri, L. Altucci, I. Amelio, DW Andrews, M. Annicchiarico-Petruzzelli, AV Antonov, E. Arama, EH Baehrecke, NA Barlev, NG Bazan, F. Bernassola, MJM Bertrand, K. Bianchi, MV Blagosklonny, K. Blomgren, C. Borner, P. Boya, C. Brenner, M. Campanella, E. Candi, D. Carmona- Gutierrez, F. Cecconi, FK Chan, NS Chandel, EH Cheng, JE Chipuk, JA Cidlowski, A. Ciechanover, GM Cohen, M. Conrad, JR Cubillos-Ruiz, PE Czabotar, V. D&#039;Angiolella, TM Dawson, VL Dawson, V. De Laurenzi, R. De Maria, KM Debatin, RJ DeBerardinis, M. Deshmukh, N. Di Daniele, F. Di Virgilio, VM Dixit, SJ Dixon, CS Duckett, BD Dynlacht, WS El-Deiry, JW Elrod, GM Fimia, S. Fulda, AJ Garc\u00eda-S\u00e1ez, AD Garg, C. Garrido, E. Gavathiotis, P. Golstein, E. Gottlieb, DR Green, LA Greene, H. Gronemeyer, A. Gross, G. Hajnoczky , JM Hardwick, IS Harris, MO Hengartner, C. Hetz, H. Ichijo, M. J\u00e4\u00e4ttel\u00e4, B. Joseph, PJ Jost, PP Juin, WJ Kaiser, M. Karin, T. Kaufmann, O. Kepp, A. Kimchi , RN Kitsis, DJ Klionsky, RA Knight, S. Kumar, SW Lee, JJ Lemasters, B. Levine, A. Linkermann, SA Lipton, RA Lockshin, C. L\u00f3pez-Ot\u00edn, SW Lowe, T. Luedde, E. Lugli , M. MacFarlane, F. Madeo, M. Malewicz, W. Malorni, G. Manic, JC Marine, SJ Martin, JC Martinou, JP Medema, P. Mehlen, P. Meier, S. Melino, EA Miao, JD Molkentin , UM Moll, C. Mu\u00f1oz-Pinedo, S. Nagata, G. Nu\u00f1ez, A. Oberst, M. Oren, M. Overholtzer, M. Pagano, T. Panaretakis, M. Pasparakis, JM Penninger, DM Pereira, S. Pervaiz, ME Peter, M. Piacentini, P. Pinton, JHM Prehn, H. Puthalakath, GA Rabinovich, M. Rehm, R. Rizzuto, CMP Rodrigues, DC Rubinsztein, T. Rudel, KM Ryan, E. Sayan, L. Scorrano, F. Shao, Y. Shi, J. Silke, HU Simon, A. Sistigu, BR Stockwell, A. Strasser, G. Szabadkai, SWG Tait, D. Tang, N. Tavernarakis, A. Thorburn, Y. Tsujimoto , B. Turk, T. Vanden Berghe, P. Vandenabeele, MG Vander Heiden, A. Villunger, HW Virgin, KH Vousden, D. Vucic, EF Wagner, H. Walczak, D. Wallach, Y. Wang, JA Wells, W. \uc6b0\ub4dc, J. \uc704\uc548, Z. Zakeri, B. Zhivotovsky, L. Zitvogel, G. Melino, G. Kroemer<\/div>\n<div id=\"ref-id-sbref92\" class=\"title text-m\">\uc138\ud3ec \uc0ac\uba78\uc758 \ubd84\uc790 \uba54\ucee4\ub2c8\uc998: 2018\ub144 \uc138\ud3ec \uc0ac\uba78 \uba85\uba85\ubc95 \uc704\uc6d0\ud68c\uc758 \uad8c\uc7a5 \uc0ac\ud56d<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Cell Death Different., 25 (3) (2018), pp. 486-541,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1038\/s41418-017-0012-4\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1038\/s41418-017-0012-4<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85036533976&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref92\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Molecular%20mechanisms%20of%20cell%20death%3A%20recommendations%20of%20the%20Nomenclature%20Committee%20on%20Cell%20Death%202018&amp;publication_year=2018&amp;author=L.%20Galluzzi&amp;author=I.%20Vitale&amp;author=S.A.%20Aaronson&amp;author=J.M.%20Abrams&amp;author=D.%20Adam&amp;author=P.%20Agostinis&amp;author=E.S.%20Alnemri&amp;author=L.%20Altucci&amp;author=I.%20Amelio&amp;author=D.W.%20Andrews&amp;author=M.%20Annicchiarico-Petruzzelli&amp;author=A.V.%20Antonov&amp;author=E.%20Arama&amp;author=E.H.%20Baehrecke&amp;author=N.A.%20Barlev&amp;author=N.G.%20Bazan&amp;author=F.%20Bernassola&amp;author=M.J.M.%20Bertrand&amp;author=K.%20Bianchi&amp;author=M.V.%20Blagosklonny&amp;author=K.%20Blomgren&amp;author=C.%20Borner&amp;author=P.%20Boya&amp;author=C.%20Brenner&amp;author=M.%20Campanella&amp;author=E.%20Candi&amp;author=D.%20Carmona-Gutierrez&amp;author=F.%20Cecconi&amp;author=F.K.%20Chan&amp;author=N.S.%20Chandel&amp;author=E.H.%20Cheng&amp;author=J.E.%20Chipuk&amp;author=J.A.%20Cidlowski&amp;author=A.%20Ciechanover&amp;author=G.M.%20Cohen&amp;author=M.%20Conrad&amp;author=J.R.%20Cubillos-Ruiz&amp;author=P.E.%20Czabotar&amp;author=V.%20D%27Angiolella&amp;author=T.M.%20Dawson&amp;author=V.L.%20Dawson&amp;author=V.%20De%20Laurenzi&amp;author=R.%20De%20Maria&amp;author=K.M.%20Debatin&amp;author=R.J.%20DeBerardinis&amp;author=M.%20Deshmukh&amp;author=N.%20Di%20Daniele&amp;author=F.%20Di%20Virgilio&amp;author=V.M.%20Dixit&amp;author=S.J.%20Dixon&amp;author=C.S.%20Duckett&amp;author=B.D.%20Dynlacht&amp;author=W.S.%20El-Deiry&amp;author=J.W.%20Elrod&amp;author=G.M.%20Fimia&amp;author=S.%20Fulda&amp;author=A.J.%20Garc%C3%ADa-S%C3%A1ez&amp;author=A.D.%20Garg&amp;author=C.%20Garrido&amp;author=E.%20Gavathiotis&amp;author=P.%20Golstein&amp;author=E.%20Gottlieb&amp;author=D.R.%20Green&amp;author=L.A.%20Greene&amp;author=H.%20Gronemeyer&amp;author=A.%20Gross&amp;author=G.%20Hajnoczky&amp;author=J.M.%20Hardwick&amp;author=I.S.%20Harris&amp;author=M.O.%20Hengartner&amp;author=C.%20Hetz&amp;author=H.%20Ichijo&amp;author=M.%20J%C3%A4%C3%A4ttel%C3%A4&amp;author=B.%20Joseph&amp;author=P.J.%20Jost&amp;author=P.P.%20Juin&amp;author=W.J.%20Kaiser&amp;author=M.%20Karin&amp;author=T.%20Kaufmann&amp;author=O.%20Kepp&amp;author=A.%20Kimchi&amp;author=R.N.%20Kitsis&amp;author=D.J.%20Klionsky&amp;author=R.A.%20Knight&amp;author=S.%20Kumar&amp;author=S.W.%20Lee&amp;author=J.J.%20Lemasters&amp;author=B.%20Levine&amp;author=A.%20Linkermann&amp;author=S.A.%20Lipton&amp;author=R.A.%20Lockshin&amp;author=C.%20L%C3%B3pez-Ot%C3%ADn&amp;author=S.W.%20Lowe&amp;author=T.%20Luedde&amp;author=E.%20Lugli&amp;author=M.%20MacFarlane&amp;author=F.%20Madeo&amp;author=M.%20Malewicz&amp;author=W.%20Malorni&amp;author=G.%20Manic&amp;author=J.C.%20Marine&amp;author=S.J.%20Martin&amp;author=J.C.%20Martinou&amp;author=J.P.%20Medema&amp;author=P.%20Mehlen&amp;author=P.%20Meier&amp;author=S.%20Melino&amp;author=E.A.%20Miao&amp;author=J.D.%20Molkentin&amp;author=U.M.%20Moll&amp;author=C.%20Mu%C3%B1oz-Pinedo&amp;author=S.%20Nagata&amp;author=G.%20Nu%C3%B1ez&amp;author=A.%20Oberst&amp;author=M.%20Oren&amp;author=M.%20Overholtzer&amp;author=M.%20Pagano&amp;author=T.%20Panaretakis&amp;author=M.%20Pasparakis&amp;author=J.M.%20Penninger&amp;author=D.M.%20Pereira&amp;author=S.%20Pervaiz&amp;author=M.E.%20Peter&amp;author=M.%20Piacentini&amp;author=P.%20Pinton&amp;author=J.H.M.%20Prehn&amp;author=H.%20Puthalakath&amp;author=G.A.%20Rabinovich&amp;author=M.%20Rehm&amp;author=R.%20Rizzuto&amp;author=C.M.P.%20Rodrigues&amp;author=D.C.%20Rubinsztein&amp;author=T.%20Rudel&amp;author=K.M.%20Ryan&amp;author=E.%20Sayan&amp;author=L.%20Scorrano&amp;author=F.%20Shao&amp;author=Y.%20Shi&amp;author=J.%20Silke&amp;author=H.U.%20Simon&amp;author=A.%20Sistigu&amp;author=B.R.%20Stockwell&amp;author=A.%20Strasser&amp;author=G.%20Szabadkai&amp;author=S.W.G.%20Tait&amp;author=D.%20Tang&amp;author=N.%20Tavernarakis&amp;author=A.%20Thorburn&amp;author=Y.%20Tsujimoto&amp;author=B.%20Turk&amp;author=T.%20Vanden%20Berghe&amp;author=P.%20Vandenabeele&amp;author=M.G.%20Vander%20Heiden&amp;author=A.%20Villunger&amp;author=H.W.%20Virgin&amp;author=K.H.%20Vousden&amp;author=D.%20Vucic&amp;author=E.F.%20Wagner&amp;author=H.%20Walczak&amp;author=D.%20Wallach&amp;author=Y.%20Wang&amp;author=J.A.%20Wells&amp;author=W.%20Wood&amp;author=J.%20Yuan&amp;author=Z.%20Zakeri&amp;author=B.%20Zhivotovsky&amp;author=L.%20Zitvogel&amp;author=G.%20Melino&amp;author=G.%20Kroemer\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref92\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib93\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib93\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[93]<\/span><\/a><\/span>\n<div class=\"other-ref\">\uc790\uac00\ud3ec\uc2dd\uc758 \uc57d\ub9ac\ud559\uc801 \uc870\uc808: \uce58\ub8cc \uc7a0\uc7ac\ub825\uacfc \uc9c0\uc18d\uc801\uc778 \uc7a5\uc560.Nat Rev Drug Discov. 2017;16(7):487\u2013511.<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar?q=Pharmacological%20modulation%20of%20autophagy%3A%20therapeutic%20potential%20and%20persisting%20obstacles.Nat%20Rev%20Drug%20Discov.%202017%3B16(7)%3A487%E2%80%93511.\" target=\"_blank\" rel=\"noopener noreferrer\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib94\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib94\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[94]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">N. \ubbf8\uc988\uc2dc\ub9c8, M. \uace0\ub9c8\uce20<\/div>\n<div id=\"ref-id-sbref93\" class=\"title text-m\">\uc790\uac00\ud3ec\uc2dd: \uc138\ud3ec\uc640 \uc870\uc9c1\uc758 \uc7ac\uc0dd<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc138\ud3ec, 147(4)(2011), pp. 728-741<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0092867411012761\/pdfft?md5=187f8f0c464a2b1f3f0cfc9472e694e5&amp;pid=1-s2.0-S0092867411012761-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref93\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0092867411012761\" aria-describedby=\"ref-id-sbref93\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-81055144784&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref93\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Autophagy%3A%20renovation%20of%20cells%20andtissues&amp;publication_year=2011&amp;author=N.%20Mizushima&amp;author=M.%20Komatsu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref93\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib95\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib95\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[95]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">V. Sagulenko, SJ Thygesen, DP Sester,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref94\" class=\"title text-m\">AIM2 \ubc0f NLRP3 \uc778\ud50c\ub77c\ub9c8\uc19c\uc740 ASC\ub97c \ud1b5\ud574 \uc138\ud3ec\uc0ac\uba78 \ubc0f \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uc0ac\ub9dd \uacbd\ub85c\ub97c \ubaa8\ub450 \ud65c\uc131\ud654\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Cell death Different., 20 (9) (2013), pp. 1149-1160,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1038\/cdd.2013.37\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1038\/cdd.2013.37<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84882280029&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref94\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=AIM2%20and%20NLRP3%20inflammasomes%20activate%20both%20apoptotic%20and%20pyroptotic%20death%20pathways%20via%20ASC&amp;publication_year=2013&amp;author=V.%20Sagulenko&amp;author=S.J.%20Thygesen&amp;author=D.P.%20Sester\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref94\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib96\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib96\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[96]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">J. \ud6c4\ucfe0\ubaa8\ud1a0, I. \ud6c4\ucfe0\ubaa8\ud1a0, PT Parthasarathy,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref95\" class=\"title text-m\">NLRP3 \uacb0\uc2e4\uc740 \uacfc\uc0b0\uc18c\uc99d\uc73c\ub85c \uc778\ud55c \uae09\uc131 \ud3d0 \uc190\uc0c1\uc73c\ub85c\ubd80\ud130 \ubcf4\ud638\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc624\uc804. JPhysiol, 305 (1 Pt.1) (2013), pp. C182-C189,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1152\/ajpcell.00086.2013\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1152\/ajpcell.00086.2013<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84880172305&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref95\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=NLRP3%20deletionprotects%20from%20hyperoxia%20-induced%20acute%20lung%20injury&amp;publication_year=2013&amp;author=J.%20Fukumoto&amp;author=I.%20Fukumoto&amp;author=P.T.%20Parthasarathy\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref95\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib97\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib97\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[97]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">PC Liao, LK Chao, JC Chou,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref96\" class=\"title text-m\">NLRP3 \ub2e8\ubc31\uc9c8 \ubc1c\ud604 \ubc0f easpase-1 \ub9e4\uac1c \uc778\ud130\ub8e8\ud0a8-1 \u03b2 \ubd84\ube44 \uc870\uc808\uc5d0\uc11c \uc9c0\uc9c8\ub2e4\ub2f9\ub958\/\uc544\ub370\ub178\uc2e0 \uc0bc\uc778\uc0b0 \ub9e4\uac1c \uc2e0\ud638 \uc804\ub2ec<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc5fc\uc99d. \uacb0\uc758\uc548, 62(1)(2013), 89-96\ud398\uc774\uc9c0,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1007\/s00011-012.0555.2\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1007\/s00011-012.0555.2<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84872290052&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref96\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Lipopolysaccharideadenosine%20triphosphate-mediated%20signal%20transduction%20in%20the%20regulation%20of%20NLRP3%20protein%20expression%20and%20easpase-1-mediated%20interleukin-1%20%20secretion&amp;publication_year=2013&amp;author=P.C.%20Liao&amp;author=L.K.%20Chao&amp;author=J.C.%20Chou\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref96\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib98\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib98\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[98]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Z. Liu, G. Lu, Y. Xu,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref97\" class=\"title text-m\">\uba5c\ub77c\ud1a0\ub2cc\uc740 \uc0dd\uc950 \uc9c0\ubc29\uc870\uc9c1\uc5d0\uc11c NF-K B\/GSDMD \uc2e0\ud638\ub97c \uc5b5\uc81c\ud568\uc73c\ub85c\uc368 \uc778\ud53c\ud2b8\ub9c8\uc19c \uc720\ubc1c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc644\ud654\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">JPinealRes, 63 (1) (2017), p. 7,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1111\/jpi.12414\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1111\/jpi.12414<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Melatonin%20alleviates%20inftammasome-induced%20pyroptosis%20through%20inhibiting%20NF-K%20BGSDMD%20signal%20in%20mice%20adiposetissue&amp;publication_year=2017&amp;author=Z.%20Liu&amp;author=G.%20Lu&amp;author=Y.%20Xu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref97\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib99\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib99\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[99]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">R. Jin, L. Liu, S. Zhang, A. Nanda, G. Li<\/div>\n<div id=\"ref-id-sbref98\" class=\"title text-m\">\uae09\uc131 \ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc5d0\uc11c \uc5fc\uc99d\uacfc \uadf8 \ub9e4\uac1c\uccb4\uc758 \uc5ed\ud560<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. Cardiovasc \ubc88\uc5ed. \uacb0\uc758\uc548, 6(5)(2013), 834-851\ud398\uc774\uc9c0,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1007\/s12265-013-9508-6\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1007\/s12265-013-9508-6<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84885638937&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref98\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Role%20of%20inflammation%20and%20its%20mediators%20in%20acute%20ischemic%20stroke&amp;publication_year=2013&amp;author=R.%20Jin&amp;author=L.%20Liu&amp;author=S.%20Zhang&amp;author=A.%20Nanda&amp;author=G.%20Li\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref98\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib100\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib100\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[100]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">CD Maida, RL Norrito, M. Daidone, A. Tuttolomondo, A. Pinto<\/div>\n<div id=\"ref-id-sbref99\" class=\"title text-m\">\ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc758 \uc2e0\uacbd\uc5fc\uc99d \uae30\uc804: \uc2ec\uc7a5\uc0c9\uc804\uc131 \ub1cc\uc878\uc911, \ubc30\uacbd \ubc0f \uce58\ub8cc \uc811\uadfc\ubc95\uc5d0 \ucd08\uc810<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Int J. Mol. Sci., 21(18)(2020), p. 6454,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.3390\/ijms21186454\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.3390\/ijms21186454<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Neuroinflammatory%20Mechanisms%20in%20Ischemic%20Stroke%3A%20Focus%20on%20Cardioembolic%20Stroke%2C%20Background%2C%20and%20Therapeutic%20Approaches&amp;publication_year=2020&amp;author=C.D.%20Maida&amp;author=R.L.%20Norrito&amp;author=M.%20Daidone&amp;author=A.%20Tuttolomondo&amp;author=A.%20Pinto\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref99\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib101\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib101\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[101]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">A. \ub098\uce74\ubb34\ub77c, K. \uc624\ud0c0\ub2c8, T. \uc2dc\uce58\ud0c0<\/div>\n<div id=\"ref-id-sbref100\" class=\"title text-m\">\ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc758 \uc9c0\uc9c8 \ub9e4\uac1c\uccb4\uc640 \ubb34\uade0 \uc5fc\uc99d<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Int Immunol., 32 (11) (2020), pp. 719-725,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1093\/intimm\/dxaa027\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1093\/intimm\/dxaa027<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Lipid%20mediators%20and%20sterile%20inflammation%20in%20ischemic%20stroke&amp;publication_year=2020&amp;author=A.%20Nakamura&amp;author=K.%20Otani&amp;author=T.%20Shichita\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref100\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib102\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib102\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[102]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">S. Xu, J. Lu, A. Shao, JH Zhang, J. Zhang<\/div>\n<div id=\"ref-id-sbref101\" class=\"title text-m\">\uc2e0\uacbd\uad50 \uc138\ud3ec: \ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc5d0\uc11c \uba74\uc5ed \ubc18\uc751\uc758 \uc5ed\ud560<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Front Immunol., 11 (2020), p. 294,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.3389\/fimmu.2020.00294\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.3389\/fimmu.2020.00294<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85081952500&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref101\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Glial%20Cells%3A%20Role%20of%20the%20Immune%20Response%20in%20Ischemic%20Stroke&amp;publication_year=2020&amp;author=S.%20Xu&amp;author=J.%20Lu&amp;author=A.%20Shao&amp;author=J.H.%20Zhang&amp;author=J.%20Zhang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref101\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib103\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib103\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[103]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Y. Zhai, X. Meng, T. Ye,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref102\" class=\"title text-m\">MCC950\uc73c\ub85c NLRP3 \uc778\ud50c\ub77c\ub9c8\uc19c \ud65c\uc131\ud654\ub97c \uc5b5\uc81c\ud558\uba74 db\/db \ub9c8\uc6b0\uc2a4\uc5d0\uc11c \ub2f9\ub1e8\ubcd1\uc131 \ub1cc\ubcd1\uc99d\uc774 \uac1c\uc120\ub429\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ubd84\uc790, 23(3)(2018)<\/div>\n<div class=\"comment\">\ud30c\uc774:E522<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Inhibiting%20the%20NLRP3%20Inflammasome%20Activation%20with%20MCC950%20Ameliorates%20Diabetic%20Encephalopathy%20in%20dbdb%20Mice&amp;publication_year=2018&amp;author=Y.%20Zhai&amp;author=X.%20Meng&amp;author=T.%20Ye\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref102\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib104\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib104\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[104]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">L. \uc644, X. \uc704\uc548, M. \ub9ac\uc6b0,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref103\" class=\"title text-m\">miRNA-223-3p\ub294 NLRP3\ub97c \uc870\uc808\ud558\uc5ec \uc138\ud3ec\uc0ac\uba78\uc744 \ucd09\uc9c4\ud558\uace0 hep3B \uc138\ud3ec\uc758 \uc99d\uc2dd\uc744 \uc5b5\uc81c\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud2b9\uae09. \uac70\uae30. \uba54\ub4dc, 15(3)(2018)<\/div>\n<div class=\"comment\">2 429-2 435<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=miRNA-223-3p%20regulates%20NLRP3to%20promote%20apoptosis%20and%20inhibit%20proliferation%20of%20hep3B%20cells&amp;publication_year=2018&amp;author=L.%20Wan&amp;author=X.%20Yuan&amp;author=M.%20Liu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref103\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib105\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib105\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[105]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">J. Liao, VS Kapadia, LS Brown, N. Cheong, C. Longoria, D. Mija, M. Ramgopal, J. Mirpuri, DC McCurnin, RC Savani<\/div>\n<div id=\"ref-id-sbref104\" class=\"title text-m\">NLRP3 \uc778\ud50c\ub77c\ub9c8\uc19c\uc740 \uae30\uad00\uc9c0\ud3d0 \uc774\ud615\uc131\uc99d\uc758 \ubc1c\ubcd1\uc5d0 \uacb0\uc815\uc801\uc73c\ub85c \uad00\uc5ec\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Nat. Commun., 6(2015), p. 8977,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1038\/ncomms9977\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1038\/ncomms9977<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84948708402&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref104\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20NLRP3%20inflammasome%20is%20critically%20involved%20in%20the%20development%20of%20bronchopulmonary%20dysplasia&amp;publication_year=2015&amp;author=J.%20Liao&amp;author=V.S.%20Kapadia&amp;author=L.S.%20Brown&amp;author=N.%20Cheong&amp;author=C.%20Longoria&amp;author=D.%20Mija&amp;author=M.%20Ramgopal&amp;author=J.%20Mirpuri&amp;author=D.C.%20McCurnin&amp;author=R.C.%20Savani\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref104\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib106\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib106\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[106]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">X. Wang, R. Huo, Z. Liang, C. Xu, T. Chen, J. Lin, L. Li, W. Lin, B. Pan, X. Fu, S. Chen<\/div>\n<div id=\"ref-id-sbref105\" class=\"title text-m\">\uc2ec\ubc14\uc2a4\ud0c0\ud2f4\uc740 NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4 \ud65c\uc131\ud654\ub97c \uc5b5\uc81c\ud558\uace0 KLF2 \ub9e4\uac1c \uba54\ucee4\ub2c8\uc998\uc744 \ud1b5\ud574 \uacfc\uc0b0\uc18c\uc99d \uc720\ubc1c \uae30\uad00\uc9c0\ud3d0 \uc774\ud615\uc131\uc99d\uc758 \ud3d0 \uc190\uc0c1\uc744 \uac1c\uc120\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc0b0\ud654\ubb3c. Med Cell Longev., 2022(2022), \uc870\ud56d 8336070,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1155\/2022\/8336070\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1155\/2022\/8336070<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85129437673&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref105\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Simvastatin%20inhibits%20NLRP3%20inflammasome%20activation%20and%20ameliorates%20lung%20injury%20in%20hyperoxia-induced%20bronchopulmonary%20dysplasia%20via%20the%20KLF2-mediated%20mechanism&amp;publication_year=2022&amp;author=X.%20Wang&amp;author=R.%20Huo&amp;author=Z.%20Liang&amp;author=C.%20Xu&amp;author=T.%20Chen&amp;author=J.%20Lin&amp;author=L.%20Li&amp;author=W.%20Lin&amp;author=B.%20Pan&amp;author=X.%20Fu&amp;author=S.%20Chen\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref105\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib107\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib107\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[107]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">T. \ud558\uc138\uac00\uc640, M. \ub098\uce74\uc2dc\ub9c8, Y. \uc2a4\uc988\ud0a4<\/div>\n<div id=\"ref-id-sbref106\" class=\"title text-m\">\ud575 DNA \uc190\uc0c1\uc73c\ub85c \uc778\ud55c NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4 \ud65c\uc131\ud654\ub294 \uc778\uac04 \uac01\uc9c8\ud615\uc131\uc138\ud3ec\uc5d0\uc11c UVB \uc720\ubc1c \uc5fc\uc99d \ubc18\uc751\uc744 \ucd09\uc9c4\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc0dd\ud654\ud559 \uc0dd\ubb3c\ubb3c\ub9ac\ud559. Res Commun., 477 (3) (2016), pp. 329-335,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.bbrc.2016.06.106\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.bbrc.2016.06.106<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006291X16310245\/pdfft?md5=754cf8fa78ec85afaa149d567901fc05&amp;pid=1-s2.0-S0006291X16310245-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref106\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006291X16310245\" aria-describedby=\"ref-id-sbref106\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84978879552&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref106\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Nuclear%20DNA%20damage-triggered%20NLRP3%20inflammasome%20activation%20promotes%20UVB-induced%20inflammatory%20responses%20in%20human%20keratinocytes&amp;publication_year=2016&amp;author=T.%20Hasegawa&amp;author=M.%20Nakashima&amp;author=Y.%20Suzuki\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref106\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib108\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib108\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[108]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">L. Hou, Z. Yang, Z. Wang, X. Zhang, Y. Zhao, H. Yang, B. Zheng, W. Tian, S. Wang, Z. He, X. Wang<\/div>\n<div id=\"ref-id-sbref107\" class=\"title text-m\">NLRP3\/ASC \ub9e4\uac1c \ud3d0\ud3ec \ub300\uc2dd\uc138\ud3ec \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub294 \uc2ec\ud3d0 \uc6b0\ud68c\uc220\ub85c \uc720\ubc1c\ub41c \uae09\uc131 \ud3d0 \uc190\uc0c1\uc5d0\uc11c HMGB1 \ubd84\ube44\ub97c \ud5a5\uc0c1\uc2dc\ud0b5\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Lab Invest, 98(8)(2018), pp. 1052-1064,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1038\/s41374-018-0073-0\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1038\/s41374-018-0073-0<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0023683722011035\/pdfft?md5=52cf1adba7ef6f4348e6632a9f8e01c9&amp;pid=1-s2.0-S0023683722011035-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref107\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0023683722011035\" aria-describedby=\"ref-id-sbref107\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85048177565&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref107\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=NLRP3ASC-mediated%20alveolar%20macrophage%20pyroptosis%20enhances%20HMGB1%20secretion%20in%20acute%20lung%20injury%20induced%20by%20cardiopulmonary%20bypass&amp;publication_year=2018&amp;author=L.%20Hou&amp;author=Z.%20Yang&amp;author=Z.%20Wang&amp;author=X.%20Zhang&amp;author=Y.%20Zhao&amp;author=H.%20Yang&amp;author=B.%20Zheng&amp;author=W.%20Tian&amp;author=S.%20Wang&amp;author=Z.%20He&amp;author=X.%20Wang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref107\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib109\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib109\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[109]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">A. \ub9b0\ub354, V. \ud638\ub219<\/div>\n<div id=\"ref-id-sbref108\" class=\"title text-m\">T \uc138\ud3ec\uc758 \uc5fc\uc99d\ubcf5\ud569\uccb4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J.Mol. Biol., 434 (4) (2022), \uc870\ud56d 167275,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.jmb.2021.167275\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.jmb.2021.167275<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S002228362100512X\/pdfft?md5=15b7a8f2313331f905467f8e0eaee7eb&amp;pid=1-s2.0-S002228362100512X-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref108\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S002228362100512X\" aria-describedby=\"ref-id-sbref108\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85117396292&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref108\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Inflammasomes%20in%20T%20cells&amp;publication_year=2022&amp;author=A.%20Linder&amp;author=V.%20Hornung\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref108\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib110\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib110\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[110]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">FM Hughes Jr, HM Hill, CM Wood, AT Edmondson, A. Dumas, WC Foo, JM Oelsen, G. Rac, JT Purves<\/div>\n<div id=\"ref-id-sbref109\" class=\"title text-m\">NLRP3 Inflammasome\uc740 \ubc29\uad11\ucd9c\uad6c \ud3d0\uc1c4\ub85c \uc778\ud574 \uc0dd\uc131\ub41c \uc5fc\uc99d\uc744 \uc911\uc7ac\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. Urol., 195 (5) (2016), pp. 1598-1605,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.juro.2015.12.068\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.juro.2015.12.068<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0022534715054439\/pdfft?md5=7790eeff799f0d556eef9fa05beabf3f&amp;pid=1-s2.0-S0022534715054439-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref109\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0022534715054439\" aria-describedby=\"ref-id-sbref109\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84962270898&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref109\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20NLRP3%20Inflammasome%20Mediates%20Inflammation%20Produced%20by%20Bladder%20Outlet%20Obstruction&amp;publication_year=2016&amp;author=F.M.%20Hughes%20Jr&amp;author=H.M.%20Hill&amp;author=C.M.%20Wood&amp;author=A.T.%20Edmondson&amp;author=A.%20Dumas&amp;author=W.C.%20Foo&amp;author=J.M.%20Oelsen&amp;author=G.%20Rac&amp;author=J.T.%20Purves\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref109\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib111\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib111\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[111]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Q. Yu, T. Zhao, M. Liu, D. Cao, J. Li, Y. Li, M. Xia, X. Wang, T. Zheng, C. Liu, X. Mu, P. Sun<\/div>\n<div id=\"ref-id-sbref110\" class=\"title text-m\">\uc2e0\uacbd\uacc4 \uc9c8\ud658\uc758 \ubcd1\uc9c4 \uce58\ub8cc\uc5d0\uc11c NLRP3 \uc778\ud50c\ub77c\ub9c8\uc19c \ud45c\uc801\ud654: \uc5c5\ub370\uc774\ud2b8<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Front Pharm., 12(2021), \uc870\ud56d 707696,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.3389\/fphar.2021.707696\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.3389\/fphar.2021.707696<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85114828635&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref110\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Targeting%20NLRP3%20inflammasome%20in%20translational%20treatment%20of%20nervous%20system%20diseases%3A%20an%20update&amp;publication_year=2021&amp;author=Q.%20Yu&amp;author=T.%20Zhao&amp;author=M.%20Liu&amp;author=D.%20Cao&amp;author=J.%20Li&amp;author=Y.%20Li&amp;author=M.%20Xia&amp;author=X.%20Wang&amp;author=T.%20Zheng&amp;author=C.%20Liu&amp;author=X.%20Mu&amp;author=P.%20Sun\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref110\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib112\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib112\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[112]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">L. \ud53c\uc5b4\uc2a4, SM \ub370\uc774\ube44\uc2a8, DM \uc610\ub860<\/div>\n<div id=\"ref-id-sbref111\" class=\"title text-m\">\uc6d0\uaca9 \ud5c8\ud608\uc131 \uc870\uc808\uc774 \uc5fc\uc99d\uc744 \uac10\uc18c\uc2dc\ud0a4\ub098\uc694? \uc120\ucc9c\uba74\uc5ed\uacfc \uc0ac\uc774\ud1a0\uce74\uc778 \ubc18\uc751\uc5d0 \uc911\uc810<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Basic Res Cardiol., 116 (1) (2021), p. 12,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1007\/s00395-021-00852-0\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1007\/s00395-021-00852-0<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Does%20remote%20ischaemic%20conditioning%20reduce%20inflammation%20A%20focus%20on%20innate%20immunity%20and%20cytokine%20response&amp;publication_year=2021&amp;author=L.%20Pearce&amp;author=S.M.%20Davidson&amp;author=D.M.%20Yellon\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref111\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib113\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib113\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[113]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">MJ Zhang, QC Zhao, MX Xia, J. Chen, YT Chen, X. Cao, Y. Liu, ZQ Yuan, XY Wang, Y. Xu<\/div>\n<div id=\"ref-id-sbref112\" class=\"title text-m\">HDAC3 \uc5b5\uc81c\uc81c RGFP966\uc740 AIM2 \uc5fc\uc99d\ubcf5\ud569\uccb4\ub97c \ud558\ud5a5 \uc870\uc808\ud558\uc5ec \ud5c8\ud608\uc131 \ub1cc \uc190\uc0c1\uc744 \uac1c\uc120\ud588\uc2b5\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">FASEB J., 34 (1) (2020), \ud398\uc774\uc9c0 648-662,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1096\/fj.201900394RRR\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1096\/fj.201900394RRR<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span><\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20HDAC3%20inhibitor%20RGFP966%20ameliorated%20ischemic%20brain%20damage%20by%20downregulating%20the%20AIM2%20inflammasome&amp;publication_year=2020&amp;author=M.J.%20Zhang&amp;author=Q.C.%20Zhao&amp;author=M.X.%20Xia&amp;author=J.%20Chen&amp;author=Y.T.%20Chen&amp;author=X.%20Cao&amp;author=Y.%20Liu&amp;author=Z.Q.%20Yuan&amp;author=X.Y.%20Wang&amp;author=Y.%20Xu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref112\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib114\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib114\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[114]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">H. \ub2e4\ucf00\ub2e4, T. \uc57c\ub9c8\uad6c\uce58, H. \uc57c\ub178, J. \ub2e4\ub098\uce74<\/div>\n<div id=\"ref-id-sbref113\" class=\"title text-m\">\ub1cc\uacbd\uc0c9\uc5d0\uc11c\uc758 \uc18c\uad50\uc138\ud3ec \ub300\uc0ac \uc7a5\uc560 \ubc0f \uc2e0\uacbd\uc5fc\uc99d<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J.Pharm. Sci., 145 (1) (2021), 130-139\ud398\uc774\uc9c0,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.jphs.2020.11.007\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.jphs.2020.11.007<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1347861320301134\/pdfft?md5=0d880540e6d34ae264b8c1aa3a7d6a9e&amp;pid=1-s2.0-S1347861320301134-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref113\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1347861320301134\" aria-describedby=\"ref-id-sbref113\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85097473490&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref113\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Microglial%20metabolic%20disturbances%20and%20neuroinflammation%20in%20cerebral%20infarction&amp;publication_year=2021&amp;author=H.%20Takeda&amp;author=T.%20Yamaguchi&amp;author=H.%20Yano&amp;author=J.%20Tanaka\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref113\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib115\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib115\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[115]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Z. Gong, J. Pan, Q. Shen, M. Li, Y. Peng<\/div>\n<div id=\"ref-id-sbref114\" class=\"title text-m\">\ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uae30\ub2a5 \uc7a5\uc560\ub294 \ub1cc \ud5c8\ud608 \/ \uc7ac\uad00\ub958 \uc190\uc0c1 \ub3d9\uc548 NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4 \ud65c\uc131\ud654\ub97c \uc720\ub3c4\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. \uc2e0\uacbd\uc5fc\uc99d., 15 (1) (2018), p. 242,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1186\/s12974-018-1282-6\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1186\/s12974-018-1282-6<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85052498101&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref114\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Mitochondrial%20dysfunction%20induces%20NLRP3%20inflammasome%20activation%20during%20cerebral%20ischemiareperfusion%20injury&amp;publication_year=2018&amp;author=Z.%20Gong&amp;author=J.%20Pan&amp;author=Q.%20Shen&amp;author=M.%20Li&amp;author=Y.%20Peng\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref114\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib116\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib116\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[116]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">V. \ud150, A. \uac08\ud0a8<\/div>\n<div id=\"ref-id-sbref115\" class=\"title text-m\">\ub1cc \ud5c8\ud608\/\uc7ac\uad00\ub958 \uc190\uc0c1\uc5d0\uc11c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ubcf5\ud569\uccb4 I \uc190\uc0c1\uc758 \uba54\ucee4\ub2c8\uc998. \uac00\uc124<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ubab0. Cell Neurosci., 100 (2019), \uc870\ud56d 103408,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.mcn.2019.103408\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.mcn.2019.103408<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1044743119301022\/pdfft?md5=e8a7f15cbf04494465eb254154ef01e8&amp;pid=1-s2.0-S1044743119301022-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref115\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1044743119301022\" aria-describedby=\"ref-id-sbref115\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85072219892&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref115\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Mechanism%20of%20mitochondrial%20complex%20I%20damage%20in%20brain%20ischemiareperfusion%20injury.%20A%20hypothesis&amp;publication_year=2019&amp;author=V.%20Ten&amp;author=A.%20Galkin\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref115\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib117\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib117\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[117]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">S. Liu, J. Du, D. Li, P. Yang, Y. Kou, C. Li, Q. Zhou, Y. Lu, T. Hasegawa, M. Li<\/div>\n<div id=\"ref-id-sbref116\" class=\"title text-m\">\uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\uc5d0 \uc758\ud55c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub294 MG63 \uc138\ud3ec\uc758 \uace8\ud615\uc131 \uae30\ub2a5 \uc7a5\uc560\ub97c \uc720\ubc1c\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J.Mol. Histol., 51 (3) (2020), pp. 221-232,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1007\/s10735-020-09874-9\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1007\/s10735-020-09874-9<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85083955685&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref116\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Oxidative%20stress%20induced%20pyroptosis%20leads%20to%20osteogenic%20dysfunction%20of%20MG63%20cells&amp;publication_year=2020&amp;author=S.%20Liu&amp;author=J.%20Du&amp;author=D.%20Li&amp;author=P.%20Yang&amp;author=Y.%20Kou&amp;author=C.%20Li&amp;author=Q.%20Zhou&amp;author=Y.%20Lu&amp;author=T.%20Hasegawa&amp;author=M.%20Li\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref116\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib118\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib118\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[118]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">B. Bai, Y. Yang, Q. Wang, M. Li, C. Tian, Y. Liu, LHH Aung, PF Li, T. Yu, XM Chu<\/div>\n<div id=\"ref-id-sbref117\" class=\"title text-m\">\ub0b4\ud53c \uae30\ub2a5 \uc7a5\uc560\uc758 NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc138\ud3ec \uc0ac\uba78 Dis., 11 (9) (2020), p. 776,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1038\/s41419-020-02985-x\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1038\/s41419-020-02985-x<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85091257925&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref117\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=NLRP3%20inflammasome%20in%20endothelial%20dysfunction&amp;publication_year=2020&amp;author=B.%20Bai&amp;author=Y.%20Yang&amp;author=Q.%20Wang&amp;author=M.%20Li&amp;author=C.%20Tian&amp;author=Y.%20Liu&amp;author=L.H.H.%20Aung&amp;author=P.F.%20Li&amp;author=T.%20Yu&amp;author=X.M.%20Chu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref117\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib119\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib119\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[119]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Y. Zhao, F. Yan, J. Yin, R. Pan, W. Shi, Z. Qi, Y. Fang, Y. Huang, S. Li, Y. Luo, X. Ji, KJ Liu<\/div>\n<div id=\"ref-id-sbref118\" class=\"title text-m\">\uc544\uc5f0\uacfc \ubc18\uc751\uc131 \uc0b0\uc18c \uc885 \uc0ac\uc774\uc758 \uc2dc\ub108\uc9c0 \uc0c1\ud638 \uc791\uc6a9\uc740 \uc950\uc758 \ud5c8\ud608\uc131 \ub1cc \uc190\uc0c1\uc744 \uc99d\ud3ed\uc2dc\ud0b5\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ub1cc\uc878\uc911, 49 (9) (2018), pp. 2200-2210,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1161\/STROKEAHA.118.021179\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1161\/STROKEAHA.118.021179<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85055612026&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref118\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Synergistic%20Interaction%20Between%20Zinc%20and%20Reactive%20Oxygen%20Species%20Amplifies%20Ischemic%20Brain%20Injury%20in%20Rats&amp;publication_year=2018&amp;author=Y.%20Zhao&amp;author=F.%20Yan&amp;author=J.%20Yin&amp;author=R.%20Pan&amp;author=W.%20Shi&amp;author=Z.%20Qi&amp;author=Y.%20Fang&amp;author=Y.%20Huang&amp;author=S.%20Li&amp;author=Y.%20Luo&amp;author=X.%20Ji&amp;author=K.J.%20Liu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref118\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib120\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib120\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[120]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Z. Qiu, Y. He, H. Ming, S. Lei, Y. Leng, ZY Xia, LPS \uc9c0\uc9c8\ub2e4\ub2f9\ub958<\/div>\n<div id=\"ref-id-sbref119\" class=\"title text-m\">H9C2 \uc2ec\uadfc\uc138\ud3ec\uc5d0\uc11c ROS \uc758\uc874\uc131 NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4 \ub9e4\uac1c \uc5f4\ud654\uc99d\uc744 \ud65c\uc131\ud654\ud558\uc5ec \uace0\ud608\ub2f9 \ubc0f \uc800\uc0b0\uc18c\uc99d\/\uc7ac\uc0b0\uc18c\ud654\ub85c \uc778\ud55c \uc190\uc0c1\uc744 \uc545\ud654\uc2dc\ud0b5\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. \ub2f9\ub1e8\ubcd1 \uce58\ub8cc(Diabetes Res), 2019(2019), \uc870\ud56d 8151836,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1155\/2019\/8151836\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1155\/2019\/8151836<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85062482323&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref119\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Aggravates%20High%20Glucose-%20and%20HypoxiaReoxygenation-Induced%20Injury%20through%20Activating%20ROS-Dependent%20NLRP3%20Inflammasome-Mediated%20Pyroptosis%20in%20H9C2%20Cardiomyocytes&amp;publication_year=2019&amp;author=Z.%20Qiu&amp;author=Y.%20He&amp;author=H.%20Ming&amp;author=S.%20Lei&amp;author=Y.%20Leng&amp;author=Z.Y.%20Xia&amp;author=L.P.S.%20Lipopolysaccharide\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref119\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib121\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib121\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[121]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Y. Wang, P. Shi, Q. Chen, Z. Huang, D. Zou, J. Zhang, X. Gao, Z. Lin, ROS \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544<\/div>\n<div id=\"ref-id-sbref120\" class=\"title text-m\">GSDMD \uc0b0\ud654\ub97c \uc720\ub3c4\ud558\uc5ec \ub300\uc2dd\uc138\ud3ec \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \ucd09\uc9c4\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J.Mol. Cell Biol., 11 (12) (2019), pp. 1069-1082,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1093\/jmcb\/mjz020\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1093\/jmcb\/mjz020<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85067265088&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref120\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=promote%20macrophage%20pyroptosis%20by%20inducing%20GSDMD%20oxidation&amp;publication_year=2019&amp;author=Y.%20Wang&amp;author=P.%20Shi&amp;author=Q.%20Chen&amp;author=Z.%20Huang&amp;author=D.%20Zou&amp;author=J.%20Zhang&amp;author=X.%20Gao&amp;author=Z.%20Lin&amp;author=R.O.S.%20Mitochondrial\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref120\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib122\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib122\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[122]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">MS Sun, H. Jin, X. Sun, S. Huang, FL Zhang, ZN Guo, Y. Yang<\/div>\n<div id=\"ref-id-sbref121\" class=\"title text-m\">\ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc758 \uc720\ub9ac\uae30 \uc190\uc0c1: \ud608\uad00\uc7ac\uac1c\ud1b5 \uce58\ub8cc \ud6c4 \uae09\uc131 \ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc758 \uc7a5\uc560\ubb3c<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc0b0\ud654\ubb3c. Med Cell Longev., 2018(2018), \uc870\ud56d 3804979,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1155\/2018\/3804979\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1155\/2018\/3804979<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85042159259&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref121\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Free%20Radical%20Damage%20in%20Ischemia-Reperfusion%20Injury%3A%20An%20Obstacle%20in%20Acute%20Ischemic%20Stroke%20after%20Revascularization%20Therapy&amp;publication_year=2018&amp;author=M.S.%20Sun&amp;author=H.%20Jin&amp;author=X.%20Sun&amp;author=S.%20Huang&amp;author=F.L.%20Zhang&amp;author=Z.N.%20Guo&amp;author=Y.%20Yang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref121\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib123\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib123\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[123]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">HW Shin, C. Shinotsuka, S. Torii, K. Murakami, K. Nakayama<\/div>\n<div id=\"ref-id-sbref122\" class=\"title text-m\">\ud6a8\ubaa8 Vps1p \ubc0f Dnm1p\uc640 \uc0c1\ub3d9\uc131\uc778 \uc0c8\ub85c\uc6b4 \ud3ec\uc720\ub958 \ub2e4\uc774\ub098\ubbfc \uad00\ub828 \ub2e8\ubc31\uc9c8\uc758 \uc2dd\ubcc4 \ubc0f \uc138\ud3ec\ub0b4 \uc704\uce58 \ud30c\uc545<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. Biochem, 122(3)(1997), pp. 525-530,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1093\/oxfordjournals.jbchem.a021784\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1093\/oxfordjournals.jbchem.a021784<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-0030817913&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref122\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Identification%20and%20subcellular%20localization%20of%20a%20novel%20mammalian%20dynamin-related%20protein%20homologous%20to%20yeast%20Vps1p%20and%20Dnm1p&amp;publication_year=1997&amp;author=H.W.%20Shin&amp;author=C.%20Shinotsuka&amp;author=S.%20Torii&amp;author=K.%20Murakami&amp;author=K.%20Nakayama\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref122\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib124\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib124\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[124]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">L. Zhang, F. Jiang, Y. Chen, J. Luo, S. Liu, B. Zhang, Z. Ye, W. Wang, X. Liang, W. Shi<\/div>\n<div id=\"ref-id-sbref123\" class=\"title text-m\">Necrostatin-1\uc740 Drp1 \ubc1c\ud604 \uac10\uc18c\ub97c \ud1b5\ud574 \uc950 \uad00\ud615 \uc138\ud3ec\uc8fc NRK-52E\uc5d0\uc11c \ud5c8\ud608 \uc190\uc0c1\uc73c\ub85c \uc778\ud55c \uc138\ud3ec \uc0ac\uba78\uc744 \uc57d\ud654\uc2dc\ud0b5\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Int J. Mol. Sci., 14(12)(2013), pp. 24742-24754,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.3390\/ijms141224742\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.3390\/ijms141224742<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84890943680&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref123\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Necrostatin-1%20attenuates%20ischemia%20injury%20induced%20cell%20death%20in%20rat%20tubular%20cell%20line%20NRK-52E%20through%20decreased%20Drp1%20expression&amp;publication_year=2013&amp;author=L.%20Zhang&amp;author=F.%20Jiang&amp;author=Y.%20Chen&amp;author=J.%20Luo&amp;author=S.%20Liu&amp;author=B.%20Zhang&amp;author=Z.%20Ye&amp;author=W.%20Wang&amp;author=X.%20Liang&amp;author=W.%20Shi\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref123\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib125\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib125\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[125]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">\uc720 \uccb8<\/div>\n<div id=\"ref-id-sbref124\" class=\"title text-m\">\uc778\uac04 \uc2e0\uc138\ub1e8\uad00 \uc0c1\ud53c \uc138\ud3ec\uc758 \uc800\uc0b0\uc18c\uc99d \ubc0f \uc7ac\uc0b0\uc18c\ud654\uc5d0 \uc758\ud55c \uc5f4\ubd84\ud574 \uae30\uc804\uc5d0\uc11c \ub2e4\uc774\ub098\ubbfc-1\uc758 \uc5ed\ud560 [D]<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc81c3\uad70 \uc758\uacfc\ub300\ud559(2016)<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20role%20of%20dynamin-1%20in%20the%20mechanism%20of%20hypoxia%20and%20reoxygenation-induced%20pyroptosis%20of%20human%20renal%20tubular%20epithelial%20cells%20D&amp;publication_year=2016&amp;author=Yu%20Chen\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref124\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib126\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib126\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[126]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Z. Gong, J. Pan, Q. Shen, M. Li, Y. Peng<\/div>\n<div id=\"ref-id-sbref125\" class=\"title text-m\">\ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uae30\ub2a5 \uc7a5\uc560\ub294 \ub1cc \ud5c8\ud608 \/ \uc7ac\uad00\ub958 \uc190\uc0c1 \ub3d9\uc548 NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4 \ud65c\uc131\ud654\ub97c \uc720\ub3c4\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. \uc2e0\uacbd\uc5fc\uc99d., 15 (1) (2018), p. 242,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1186\/s12974-018-1282-6\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1186\/s12974-018-1282-6<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85052498101&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref125\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Mitochondrial%20dysfunction%20induces%20NLRP3%20inflammasome%20activation%20during%20cerebral%20ischemiareperfusion%20injury&amp;publication_year=2018&amp;author=Z.%20Gong&amp;author=J.%20Pan&amp;author=Q.%20Shen&amp;author=M.%20Li&amp;author=Y.%20Peng\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref125\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib127\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib127\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[127]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">T. Zhang, MT He, XP Zhang, L. Jing, JZ Zhang<\/div>\n<div id=\"ref-id-sbref126\" class=\"title text-m\">\ub2e8\ubc31\uc9c8 2 \uacb0\ud54d\uc744 \ubd84\ub9ac\ud558\uba74 \uace0\ud608\ub2f9\uc73c\ub85c \uc778\ud55c \ub1cc \ud5c8\ud608 \uc545\ud654 \ubc0f \uc2dc\ud5d8\uad00 \ub0b4 \ubc0f \uc0dd\uccb4 \ub0b4 \uc7ac\uad00\ub958 \uc190\uc0c1 \ud6c4 NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4 \ud65c\uc131\ud654\uac00 \uac15\ud654\ub429\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Neurochem Res, 46(6)(2021), pp. 1359-1371,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1007\/s11064-021-03270-9\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1007\/s11064-021-03270-9<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85102650404&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref126\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Uncoupling%20Protein%202%20Deficiency%20Enhances%20NLRP3%20Inflammasome%20Activation%20Following%20Hyperglycemia-Induced%20Exacerbation%20of%20Cerebral%20Ischemia%20and%20Reperfusion%20Damage%20In%20Vitro%20and%20In%20Vivo&amp;publication_year=2021&amp;author=T.%20Zhang&amp;author=M.T.%20He&amp;author=X.P.%20Zhang&amp;author=L.%20Jing&amp;author=J.Z.%20Zhang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref126\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib128\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib128\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[128]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">H. Liu, X. Wu, J. Luo, L. Zhao, X. Li, H. Guo, H. Bai, W. Cui, W. Guo, D. Feng, Y. Qu<\/div>\n<div id=\"ref-id-sbref127\" class=\"title text-m\">Adiponectin \ud3a9\ud0c0\uc774\ub4dc\ub294 AMPK\/GSK-3\u03b2\ub97c \uc870\uc808\ud558\uc5ec \ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1 \ud6c4 \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\uc640 NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4 \ud65c\uc131\ud654\ub97c \uc644\ud654\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud2b9\uae09. Neurol., 329 (2020), \uc870\ud56d 113302,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.expneurol.2020.113302\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.expneurol.2020.113302<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0014488620301333\/pdfft?md5=210c46d314c2ca971bdc8cfa5da92f97&amp;pid=1-s2.0-S0014488620301333-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref127\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0014488620301333\" aria-describedby=\"ref-id-sbref127\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85083003575&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref127\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Adiponectin%20peptide%20alleviates%20oxidative%20stress%20and%20NLRP3%20inflammasome%20activation%20after%20cerebral%20ischemia-reperfusion%20injury%20by%20regulating%20AMPKGSK-3&amp;publication_year=2020&amp;author=H.%20Liu&amp;author=X.%20Wu&amp;author=J.%20Luo&amp;author=L.%20Zhao&amp;author=X.%20Li&amp;author=H.%20Guo&amp;author=H.%20Bai&amp;author=W.%20Cui&amp;author=W.%20Guo&amp;author=D.%20Feng&amp;author=Y.%20Qu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref127\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib129\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib129\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[129]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">W. Zhu, KA Romano, L. Li, JA Buffa, N. Sangwan, P. Prakash, AN Tittle, XS Li, X. Fu, C. Androjna, AJ DiDonato, K. Brinson, BD Trapp, MA Fischbach, FE \ub808\uc774, AM \ud558\uc790\ub974, JA \ub514\ub3c4\ub098\ud1a0, SL \ud558\uc820<\/div>\n<div id=\"ref-id-sbref128\" class=\"title text-m\">\uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c\uc740 \ud2b8\ub9ac\uba54\ud2f8\uc544\ubbfc N-\uc0b0\ud654\ubb3c \uacbd\ub85c\ub97c \ud1b5\ud574 \ub1cc\uc878\uc911 \uc2ec\uac01\ub3c4\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce69\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc138\ud3ec \uc219\uc8fc \ubbf8\uc0dd\ubb3c, 29 (7) (2021), pp. 1199-1208,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.chom.2021.05.002\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.chom.2021.05.002<\/span><\/a><\/div>\n<div class=\"comment\">Epub 2021\ub144 6\uc6d4 16\uc77c. PMID: 34139173; PMCID: PMC8288076<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85110457206&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref128\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Gut%20microbes%20impact%20stroke%20severity%20via%20the%20trimethylamine%20N-oxide%20pathway&amp;publication_year=2021&amp;author=W.%20Zhu&amp;author=K.A.%20Romano&amp;author=L.%20Li&amp;author=J.A.%20Buffa&amp;author=N.%20Sangwan&amp;author=P.%20Prakash&amp;author=A.N.%20Tittle&amp;author=X.S.%20Li&amp;author=X.%20Fu&amp;author=C.%20Androjna&amp;author=A.J.%20DiDonato&amp;author=K.%20Brinson&amp;author=B.D.%20Trapp&amp;author=M.A.%20Fischbach&amp;author=F.E.%20Rey&amp;author=A.M.%20Hajjar&amp;author=J.A.%20DiDonato&amp;author=S.L.%20Hazen\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref128\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib130\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib130\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[130]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">PM Bath, K. Krishnan, JP Appleton<\/div>\n<div id=\"ref-id-sbref129\" class=\"title text-m\">\uc0b0\ud654\uc9c8\uc18c \uae30\uc99d\uc790(\uc9c8\uc0b0\uc5fc),\u00a0<span class=\"small-caps\">\uc5d8<\/span>- \uae09\uc131 \ub1cc\uc878\uc911\uc744 \uc704\ud55c \uc544\ub974\uae30\ub2cc \ub610\ub294 \uc0b0\ud654\uc9c8\uc18c \ud569\uc131\ud6a8\uc18c \uc5b5\uc81c\uc81c<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ucf54\ud06c\ub780 \ub370\uc774\ud130\ubca0\uc774\uc2a4 \uc2dc\uc2a4\ud15c \uac1c\uc815\ud310, 4(4)(2017), \uc870\ud56d CD000398,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1002\/14651858.CD000398.pub2\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1002\/14651858.CD000398.pub2<\/span><\/a><\/div>\n<div class=\"comment\">PMID: 28429459; PMCID:PMC6478181.<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85018495205&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref129\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Nitric%20oxide%20donors%20%2C%20L-arginine%2C%20or%20nitric%20oxide%20synthase%20inhibitors%20for%20acute%20stroke&amp;publication_year=2017&amp;author=P.M.%20Bath&amp;author=K.%20Krishnan&amp;author=J.P.%20Appleton\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref129\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib131\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib131\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[131]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">C. Li, Z. Zhao, Y. Luo, T. Ning, P. Liu, Q. Chen, Y. Chu, Q. Guo, Y. Zhang, W. Zhou, H. Chen, Z. Zhou, Y. Wang, B. Su, H. You, T. Zhang, X. Li, H. Song, C. Li, T. Sun, C. Jiang<\/div>\n<div id=\"ref-id-sbref130\" class=\"title text-m\">\uae09\uc131 \ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc5d0\uc11c \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\ub97c \uc904\uc774\uace0 \uc5fc\uc99d\uc131 \ubbf8\uc138 \ud658\uacbd\uc744 \uc870\uc808\ud558\uc5ec \uc2e0\uacbd \ubcf4\ud638\ub97c \uc704\ud55c \ub300\uc2dd\uc138\ud3ec\ub85c \uc704\uc7a5\ud55c \uc774\uc0b0\ud654\ub9dd\uac04 \ub098\ub178\uc785\uc790<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uace0\uae09 \uacfc\ud559. (Weinh. ), 8 (20) (2021), \uc870\ud56d e2101526,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1002\/advs.202101526\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1002\/advs.202101526<\/span><\/a><\/div>\n<div class=\"comment\">Epub 2021 8\uc6d4 26\uc77c. PMID: 34436822; PMCID: PMC8529435<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Macrophage-disguised%20manganese%20dioxide%20nanoparticles%20for%20neuroprotection%20by%20reducing%20oxidative%20stress%20and%20modulating%20inflammatory%20microenvironment%20in%20acute%20ischemic%20stroke&amp;publication_year=2021&amp;author=C.%20Li&amp;author=Z.%20Zhao&amp;author=Y.%20Luo&amp;author=T.%20Ning&amp;author=P.%20Liu&amp;author=Q.%20Chen&amp;author=Y.%20Chu&amp;author=Q.%20Guo&amp;author=Y.%20Zhang&amp;author=W.%20Zhou&amp;author=H.%20Chen&amp;author=Z.%20Zhou&amp;author=Y.%20Wang&amp;author=B.%20Su&amp;author=H.%20You&amp;author=T.%20Zhang&amp;author=X.%20Li&amp;author=H.%20Song&amp;author=C.%20Li&amp;author=T.%20Sun&amp;author=C.%20Jiang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref130\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib132\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib132\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[132]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">M. Bladowski, J. Gawrys, D. Gajecki, E. Szahidewicz-Krupska, A. Sawicz-Bladowska, A. Doroszko<\/div>\n<div id=\"ref-id-sbref131\" class=\"title text-m\">\ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc5d0\uc11c \ud608\uc18c\ud310\uacfc \uc0b0\ud654\uc9c8\uc18c \uc0dd\uccb4\ubcc0\ud658\uc758 \uc5ed\ud560: \ubca4\uce58\uc5d0\uc11c \uce68\ub300 \uc606\uae4c\uc9c0\uc758 \ubc88\uc5ed\uc801 \uac80\ud1a0<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc0b0\ud654\ubb3c. Med Cell Longev., 2020(2020), \uc870\ud56d 2979260,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1155\/2020\/2979260\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1155\/2020\/2979260<\/span><\/a><\/div>\n<div class=\"comment\">PMID: 32908630; PMCID: PMC7474795.<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85090819433&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref131\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Role%20of%20the%20platelets%20and%20nitric%20oxide%20biotransformation%20in%20ischemic%20stroke%3A%20a%20translative%20review%20from%20bench%20to%20bedside&amp;publication_year=2020&amp;author=M.%20Bladowski&amp;author=J.%20Gawrys&amp;author=D.%20Gajecki&amp;author=E.%20Szahidewicz-Krupska&amp;author=A.%20Sawicz-Bladowska&amp;author=A.%20Doroszko\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref131\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib133\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib133\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[133]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">H. Liu, J. Li, F. Zhao, H. Wang, Y. Qu, D. Mu<\/div>\n<div id=\"ref-id-sbref132\" class=\"title text-m\">\uc800\uc0b0\uc18c\uc131 \ub610\ub294 \ud5c8\ud608\uc131 \ub1cc \uc190\uc0c1\uc5d0\uc11c\uc758 \uc0b0\ud654\uc9c8\uc18c \ud569\uc131\ud6a8\uc18c<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Rev. Neurosci., 26 (1) (2015), pp. 105-117,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1515\/revneuro-2014-0041\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1515\/revneuro-2014-0041<\/span><\/a><\/div>\n<div class=\"comment\">PMID: 25720056<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Nitric%20oxide%20synthase%20in%20hypoxic%20or%20ischemic%20brain%20injury&amp;publication_year=2015&amp;author=H.%20Liu&amp;author=J.%20Li&amp;author=F.%20Zhao&amp;author=H.%20Wang&amp;author=Y.%20Qu&amp;author=D.%20Mu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref132\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib134\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib134\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[134]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">JM Wiero\u0144ska, P. Cie\u015blik, L. Kalinowski<\/div>\n<div id=\"ref-id-sbref133\" class=\"title text-m\">\ub1cc \ud5c8\ud608\uc131 \uc800\uc0b0\uc18c\uc99d \ud6c4 \uacb0\uacfc \ubc0f \ud68c\ubcf5\uc5d0 \uc911\uc694\ud55c \uc694\uc778\uc778 \uc0b0\ud654\uc9c8\uc18c \uc758\uc874 \uacbd\ub85c<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc0dd\uccb4\ubd84\uc790, 11(8)(2021), p. 1097,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.3390\/biom11081097\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.3390\/biom11081097<\/span><\/a><\/div>\n<div class=\"comment\">PMID: 34439764; PMCID:PMC8392725.<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85111137770&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref133\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Nitric%20Oxide-Dependent%20Pathways%20as%20Critical%20Factors%20in%20the%20Consequences%20and%20Recovery%20after%20Brain%20Ischemic%20Hypoxia&amp;publication_year=2021&amp;author=J.M.%20Wiero%C5%84ska&amp;author=P.%20Cie%C5%9Blik&amp;author=L.%20Kalinowski\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref133\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib135\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib135\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[135]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">M. \uc5d4\ub4dc\ub808\uc2a4, G. \uc2a4\ucf67, S. \ub098\ubb34\ub77c,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref134\" class=\"title text-m\">\ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958\uc758 \uc950 \ubaa8\ub378\uc5d0\uc11c \ud3f4\ub9ac(ADP-\ub9ac\ubcf4\uc2a4) \ud569\uc131\ud6a8\uc18c\uc758 \ud65c\uc131\ud654\uc5d0\uc11c \ud37c\uc625\uc2dc\ub2c8\ud2b8\ub9ac\ud2b8 \ubc0f \ub274\ub7f0 \uc0b0\ud654\uc9c8\uc18c \ud569\uc131\ud6a8\uc18c\uc758 \uc5ed\ud560<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc2e0\uacbd \uacfc\ud559. Lett., 248(1)(1998), 41-44\ud398\uc774\uc9c0<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0304394098002249\/pdfft?md5=5dadb43b9e6af3137d2731fa74790426&amp;pid=1-s2.0-S0304394098002249-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref134\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0304394098002249\" aria-describedby=\"ref-id-sbref134\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-0032557410&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref134\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Role%20of%20peroxynitrite%20and%20neuronal%20nitric%20oxide%20synthase%20in%20the%20activation%20of%20poly%20%20synthetase%20in%20a%20murine%20model%20of%20cerebral%20ischemia-reperfusion&amp;publication_year=1998&amp;author=M.%20Endres&amp;author=G.%20Scott&amp;author=S.%20Namura\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref134\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib136\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib136\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[136]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">MJ \uc5d8\ub9ac\uc544\uc2a8, K. \uc0bc\ud398\uc774, AS \ub9cc\ub514\ub974,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref135\" class=\"title text-m\">\ud3f4\ub9ac(ADP-\ub9ac\ubcf4\uc2a4) \ud3f4\ub9ac\uba38\ub77c\uc81c \uc720\uc804\uc790 \ud30c\uad34\ub85c \uc0dd\uc950\uac00 \ub1cc \ud5c8\ud608\uc5d0 \ub0b4\uc131\uc744 \uac16\uac8c \ub428<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Nat. Med, 3 (10) (1997), pp. 1089-1095<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-0030842946&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref135\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Poly%20%20polymerase%20gene%20disruption%20renders%20mice%20resistant%20to%20cerebral%20ischemia&amp;publication_year=1997&amp;author=M.J.%20Eliasson&amp;author=K.%20Sampei&amp;author=A.S.%20Mandir\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref135\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib137\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib137\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[137]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">M. \uc5d4\ub4dc\ub808\uc2a4, ZQ \uc655, S. \ub098\ubb34\ub77c,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref136\" class=\"title text-m\">\ud5c8\ud608\uc131 \ub1cc \uc190\uc0c1\uc740 \ud3f4\ub9ac(ADP-\ub9ac\ubcf4\uc2a4) \uc911\ud569\ud6a8\uc18c\uc758 \ud65c\uc131\ud654\uc5d0 \uc758\ud574 \ub9e4\uac1c\ub429\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. Cereb. \ud608\ub958. Metab., 17(11)(1997), pp. 1143-1151<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-0030832874&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref136\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Ischemic%20brain%20injury%20is%20mediated%20by%20the%20activation%20of%20poly%20%20polymerase&amp;publication_year=1997&amp;author=M.%20Endres&amp;author=Z.Q.%20Wang&amp;author=S.%20Namura\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref136\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib138\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib138\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[138]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">R. \uc7a5, S. \ud0d5, W. \ud669,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref137\" class=\"title text-m\">\uc950\uc758 PARP-1\uc5d0 \uc758\ud574 \uc720\ubc1c\ub41c \uc2e0\uacbd\ud608\uad00 \ub2e8\uc704 \uc190\uc0c1\uc758 \uc57d\ud654\ub97c \ud1b5\ud574 \ub1cc\ud5c8\ud608 \ud6c4 \ub1cc\ub97c \ubcf4\ud638\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Brain Res, 1624(2015), \ud398\uc774\uc9c0 9-18<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006899315005521\/pdfft?md5=98a2847c7537a5e97ef01286b96d19eb&amp;pid=1-s2.0-S0006899315005521-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref137\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006899315005521\" aria-describedby=\"ref-id-sbref137\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84954236024&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref137\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Protection%20of%20the%20brain%20following%20cerebral%20ischemia%20through%20the%20attenuation%20of%20PARP-1-induced%20neurovascular%20unit%20damage%20in%20rats&amp;publication_year=2015&amp;author=R.%20Zhang&amp;author=S.%20Tang&amp;author=W.%20Huang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref137\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib139\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib139\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[139]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">L. \ubbf8\ub204\ud1a8\ub9ac, D. \ud478\uc878\ub85c, M. \ub9ac\ub0a0\ub514,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref138\" class=\"title text-m\">\ub1cc, \uc2ec\uc7a5, \uc2e0\uc7a5 \ubc0f \uace0\ud658 \ud5c8\ud608\/\uc7ac\uad00\ub958 \uc190\uc0c1\uc5d0\uc11c ROS \ub9e4\uac1c NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4 \ud65c\uc131\ud654<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc0b0\ud654\ubb3c. Med Cell Longev., 2016(2016), \uc870\ud56d 2183026<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84965131131&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref138\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=ROS-mediated%20NLRP3%20inflammasome%20activation%20in%20brain%2C%20heart%2C%20kidney%2C%20and%20testis%20ischemia%20reperfusion%20injury&amp;publication_year=2016&amp;author=L.%20Minutoli&amp;author=D.%20Puzzolo&amp;author=M.%20Rinaldi\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref138\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib140\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib140\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[140]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">P. \ud64d, \uad6c RN, FX \ub9ac,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref139\" class=\"title text-m\">\ub2f9\ub1e8\ubcd1\uacfc \ub3d9\ubc18\ub41c \ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc758 \uc7a0\uc7ac\uc801 \uce58\ub8cc\ubc95\uc778 NLRP3 \uc778\ud50c\ub77c\ub9c8\uc19c<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. \uc2e0\uacbd\uc5fc\uc99d., 16(1)(2019), p. 121<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85067036552&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref139\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=NLRP3%20inflammasome%20as%20a%20potential%20treatment%20in%20ischemic%20stroke%20concomitant%20with%20diabetes&amp;publication_year=2019&amp;author=P.%20Hong&amp;author=R.N.%20Gu&amp;author=F.X.%20Li\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref139\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib141\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib141\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[141]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">F. \uc591, Z. \uc655, X. \uc6e8\uc774,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref140\" class=\"title text-m\">NLRP3 \uacb0\ud54d\uc740 \uc2e4\ud5d8\uc801 \ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc5d0\uc11c \uc2e0\uacbd \ud608\uad00 \uc190\uc0c1\uc744 \uac1c\uc120\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. Cereb. \ud608\ub958. Metab., 34(4)(2014), pp. 660-667<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/doi.org\/10.1038\/jcbfm.2013.242\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref140\"><span class=\"anchor-text\">CrossRef<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84897575371&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref140\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=NLRP3%20deficiency%20ameliorates%20neurovascular%20damage%20in%20experimental%20ischemic%20stroke&amp;publication_year=2014&amp;author=F.%20Yang&amp;author=Z.%20Wang&amp;author=X.%20Wei\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref140\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib142\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib142\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[142]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">X. Xu, L. Zhang, X. Ye,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref141\" class=\"title text-m\">Nrf2\/ARE \uacbd\ub85c\ub294 \ub1cc \ud5c8\ud608 \uc7ac\uad00\ub958 \ud6c4 BV2 \uc138\ud3ec\uc5d0\uc11c ROS\uc5d0 \uc758\ud574 \uc720\ubc1c\ub41c NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4 \ud65c\uc131\ud654\ub97c \uc5b5\uc81c\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc5fc\uc99d. \uacb0\uc758\uc548, 67(1)(2018), 57-65\ud398\uc774\uc9c0<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/doi.org\/10.1007\/s00011-017-1095-6\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref141\"><span class=\"anchor-text\">CrossRef<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85030116523&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref141\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Nrf2ARE%20pathway%20inhibits%20ROS-induced%20NLRP3%20inflammasome%20activation%20in%20BV2%20cells%20after%20cerebral%20ischemia%20reperfusion&amp;publication_year=2018&amp;author=X.%20Xu&amp;author=L.%20Zhang&amp;author=X.%20Ye\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref141\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib143\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib143\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[143]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">I. \ubca8\ub808\uc790, S. \uadf8\ub85c\ud154\ub9ac, E. \ucf54\uc2a4\ud0c4\uc9c0,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref142\" class=\"title text-m\">Peroxynitrite\ub294 \uadfc\uc704\ucd95\uc131 \uce21\uc0ad \uacbd\ud654\uc99d\uc758 SOD1(G93A) \ub9c8\uc6b0\uc2a4 \ubaa8\ub378\uc5d0\uc11c NLRP3 \uc778\ud50c\ub77c\ub9c8\uc19c \uce90\uc2a4\ucf00\uc774\ub4dc\ub97c \ud65c\uc131\ud654\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ubab0. Neurobiol., 55 (3) (2018), pp. 2350-2361<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/doi.org\/10.1007\/s12035-017-0502-x\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref142\"><span class=\"anchor-text\">CrossRef<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85016410562&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref142\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Peroxynitrite%20activates%20the%20NLRP3%20inflammasome%20cascade%20in%20SOD1%20mouse%20model%20of%20amyotrophic%20lateral%20sclerosis&amp;publication_year=2018&amp;author=I.%20Bellezza&amp;author=S.%20Grottelli&amp;author=E.%20Costanzi\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref142\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib144\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib144\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[144]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">R. \uae38, A. Tsung, T. Billiar<\/div>\n<div id=\"ref-id-sbref143\" class=\"title text-m\">\uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\uc640 \uc5fc\uc99d\uc758 \uc5f0\uacb0: \uc720\ub8cc \uc720\uc0ac \uc218\uc6a9\uccb4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud504\ub9ac \ub77c\ub515. Biol. Med, 48 (9) (2010), pp. 1121-1132<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0891584910000110\/pdfft?md5=720f4467b4d1977cf7a66cc005dbad2b&amp;pid=1-s2.0-S0891584910000110-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref143\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0891584910000110\" aria-describedby=\"ref-id-sbref143\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-77950338003&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref143\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Linking%20oxidative%20stress%20to%20inflammation%3A%20Toll-like%20receptors&amp;publication_year=2010&amp;author=R.%20Gill&amp;author=A.%20Tsung&amp;author=T.%20Billiar\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref143\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib145\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib145\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[145]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">E. \ud30c\ub77c\ub2e4, AI \uce74\uc0ac\uc2a4, A. \ud314\ub85c\ubbf8\ub178-\uc548\ud1a8\ub9b0,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref144\" class=\"title text-m\">\ucd08\uae30 \uc720\ub8cc \uc720\uc0ac \uc218\uc6a9\uccb4 4 \ucc28\ub2e8\uc740 \uc124\uce58\ub958 \ubc0f \uc778\uac04 \ub1cc \ud5c8\ud608 \ubaa8\ub378\uc5d0\uc11c \uc18c\uad50\uc138\ud3ec \uc5fc\uc99d \uc720\ubc1c \ud45c\ud604\ud615\uc5d0 \uc758\ud574 \uc720\ubc1c\ub41c ROS \ubc0f \uc5fc\uc99d\uc744 \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ube0c\ub974. J. Pharm., 176(15)(2019), pp. 2764-2779<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/doi.org\/10.1111\/bph.14703\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref144\"><span class=\"anchor-text\">CrossRef<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85067062105&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref144\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Early%20toll-like%20receptor%204%20blockade%20reduces%20ROS%20and%20inflammation%20triggered%20by%20microglial%20pro-inflammatory%20phenotype%20in%20rodent%20and%20human%20brain%20ischaemia%20models&amp;publication_year=2019&amp;author=E.%20Parada&amp;author=A.I.%20Casas&amp;author=A.%20Palomino-Antolin\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref144\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib146\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib146\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[146]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">X. Xu, Z. Wen, N. Zhao,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref145\" class=\"title text-m\">Tolllike \uc218\uc6a9\uccb4 4\uc758 \uc0c8\ub85c\uc6b4 \uc870\uc808\uc790\uc778 MicroRNA-1906\uc740 \uc0dd\uc950\uc758 \ub1cc\uc878\uc911 \uc2e4\ud5d8 \ud6c4 \ud5c8\ud608\uc131 \uc190\uc0c1\uc744 \uac1c\uc120\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. Neurosci., 37 (43) (2017), pp. 10498-10515<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85032372046&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref145\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=MicroRNA-1906%2C%20a%20novel%20regulator%20of%20tolllike%20receptor%204%2C%20ameliorates%20ischemic%20injury%20after%20experimental%20stroke%20in%20mice&amp;publication_year=2017&amp;author=X.%20Xu&amp;author=Z.%20Wen&amp;author=N.%20Zhao\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref145\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib147\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib147\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[147]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">A. Moraga, V. G\u00f3mez-Vallejo, MI Cuartero,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref146\" class=\"title text-m\">\uc591\uc804\uc790 \ubc29\ucd9c \ub2e8\uce35 \ucd2c\uc601\uc744 \ud1b5\ud55c \ub1cc \ud5c8\ud608 \ud6c4 \uc138\ud3ec \uc99d\uc2dd \ubc0f \uc5fc\uc99d\uc5d0 \ub300\ud55c \ud1a8 \uc720\uc0ac \uc218\uc6a9\uccb4 4\uc758 \uc5ed\ud560 \uc601\uc0c1\ud654<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. Cereb. \ud608\ub958. Metab., 36(4)(2016), pp. 702-708<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Imaging%20the%20role%20of%20toll-like%20receptor%204%20on%20cell%20proliferation%20and%20inflammation%20after%20cerebral%20ischemia%20by%20positron%20emission%20tomography&amp;publication_year=2016&amp;author=A.%20Moraga&amp;author=V.%20G%C3%B3mez-Vallejo&amp;author=M.I.%20Cuartero\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref146\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib148\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib148\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[148]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Y. Qiu, Q. Yin, Y. Fei,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref147\" class=\"title text-m\">JLX001\uc740 TLR2\/4-NF-\u03baB \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub97c \uc5b5\uc81c\ud558\uc5ec pMCAO \uc950\uc758 \uc5fc\uc99d \ubc18\uc751\uacfc \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\ub97c \uc870\uc808\ud588\uc2b5\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Neurochem Res, 44 (8) (2019), pp. 1924-1938<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/doi.org\/10.1007\/s11064-019-02826-0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref147\"><span class=\"anchor-text\">CrossRef<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85067667858&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref147\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=JLX001%20modulated%20the%20inflammatory%20reaction%20and%20oxidative%20stress%20in%20pMCAO%20rats%20via%20inhibiting%20the%20TLR24-%20NF-B%20signaling%20pathway&amp;publication_year=2019&amp;author=Y.%20Qiu&amp;author=Q.%20Yin&amp;author=Y.%20Fei\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref147\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib149\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib149\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[149]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">S. Orellana-Urz\u00faa, I. Rojas, L. L\u00edbano, R. Rodrigo<\/div>\n<div id=\"ref-id-sbref148\" class=\"title text-m\">\ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc758 \ubcd1\ud0dc\uc0dd\ub9ac: \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\uc758 \uc5ed\ud560<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud604\uc7ac \uc81c\uc57d Des., 26(34)(2020), 4246-4260\ud398\uc774\uc9c0,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.2174\/1381612826666200708133912\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.2174\/1381612826666200708133912<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85090233206&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref148\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Pathophysiology%20of%20Ischemic%20Stroke%3A%20Role%20of%20Oxidative%20Stress&amp;publication_year=2020&amp;author=S.%20Orellana-Urz%C3%BAa&amp;author=I.%20Rojas&amp;author=L.%20L%C3%ADbano&amp;author=R.%20Rodrigo\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref148\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib150\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib150\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[150]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">CD Maida, RL Norrito, M. Daidone, A. Tuttolomondo, A. Pinto<\/div>\n<div id=\"ref-id-sbref149\" class=\"title text-m\">\ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc758 \uc2e0\uacbd\uc5fc\uc99d \uae30\uc804: \uc2ec\uc7a5\uc0c9\uc804\uc131 \ub1cc\uc878\uc911, \ubc30\uacbd \ubc0f \uce58\ub8cc \uc811\uadfc\ubc95\uc5d0 \ucd08\uc810<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Int J. Mol. Sci., 21(18)(2020), p. 6454,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.3390\/ijms21186454\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.3390\/ijms21186454<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Neuroinflammatory%20Mechanisms%20in%20Ischemic%20Stroke%3A%20Focus%20on%20Cardioembolic%20Stroke%2C%20Background%2C%20and%20Therapeutic%20Approaches&amp;publication_year=2020&amp;author=C.D.%20Maida&amp;author=R.L.%20Norrito&amp;author=M.%20Daidone&amp;author=A.%20Tuttolomondo&amp;author=A.%20Pinto\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref149\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib151\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib151\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[151]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Z. He, N. Ning, Q. Zhou, SE Khoshnam, M. Farzaneh<\/div>\n<div id=\"ref-id-sbref150\" class=\"title text-m\">\ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc758 \uce58\ub8cc \ud45c\uc801\uc73c\ub85c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud504\ub9ac \ub77c\ub515. Biol. Med, 146(2020), 45-58\ud398\uc774\uc9c0,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.freeradbiomed.2019.11.005\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.freeradbiomed.2019.11.005<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0891584919313577\/pdfft?md5=dd417347341ad075adedb60988f7c4a6&amp;pid=1-s2.0-S0891584919313577-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref150\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0891584919313577\" aria-describedby=\"ref-id-sbref150\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85075422408&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref150\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Mitochondria%20as%20a%20therapeutic%20target%20for%20ischemic%20stroke&amp;publication_year=2020&amp;author=Z.%20He&amp;author=N.%20Ning&amp;author=Q.%20Zhou&amp;author=S.E.%20Khoshnam&amp;author=M.%20Farzaneh\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref150\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib152\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib152\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[152]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Y. Okada, T. Numata, K. Sato-Numata, RZ Sabirov, H. Liu, SI Mori, S. Morishima<\/div>\n<div id=\"ref-id-sbref151\" class=\"title text-m\">\uc138\ud3ec\uc0ac\uba78, \uc2dc\uc2a4\ud50c\ub77c\ud2f4 \uc800\ud56d\uc131, \uad34\uc0ac, \ud5c8\ud608\uc131 \uc138\ud3ec \uc0ac\uba78, \ub1cc\uc878\uc911 \ubc0f \uc2ec\uadfc\uacbd\uc0c9\uc5d0\uc11c \ubd80\ud53c \uc870\uc808 \uc74c\uc774\uc628 \ucc44\ub110\uc778 VSOR \ubc0f Maxi-Cl\uc758 \uc5ed\ud560<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud604\uc7ac \ub9e8 \uc704. \ud68c\uc6d0, 83 (2019), pp. 205-283,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/bs.ctm.2019.03.001\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/bs.ctm.2019.03.001<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1063582319300110\/pdfft?md5=1d1791f0b9c14fcc751e4204e0df8fc4&amp;pid=1-s2.0-S1063582319300110-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref151\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1063582319300110\" aria-describedby=\"ref-id-sbref151\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85064429476&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref151\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Roles%20of%20volume-regulatory%20anion%20channels%2C%20VSOR%20and%20Maxi-Cl%2C%20in%20apoptosis%2C%20cisplatin%20resistance%2C%20necrosis%2C%20ischemic%20cell%20death%2C%20stroke%20and%20myocardial%20infarction&amp;publication_year=2019&amp;author=Y.%20Okada&amp;author=T.%20Numata&amp;author=K.%20Sato-Numata&amp;author=R.Z.%20Sabirov&amp;author=H.%20Liu&amp;author=S.I.%20Mori&amp;author=S.%20Morishima\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref151\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib153\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib153\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[153]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Y. \uc790\uc624, X. \uc7a5, X. \uccb8, Y. \uc6e8\uc774<\/div>\n<div id=\"ref-id-sbref152\" class=\"title text-m\">\ub1cc\uacbd\uc0c9 \ubc0f \ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc758 \uc2e0\uacbd \uc190\uc0c1: \uba54\ucee4\ub2c8\uc998\ubd80\ud130 \uce58\ub8cc\uae4c\uc9c0(\ub9ac\ubdf0)<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Int J. Mol. Med., 49(2)(2022), p. 15,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.3892\/ijmm.2021.5070\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.3892\/ijmm.2021.5070<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Neuronal%20injuries%20in%20cerebral%20infarction%20and%20ischemic%20stroke%3A%20from%20mechanisms%20to%20treatment%20&amp;publication_year=2022&amp;author=Y.%20Zhao&amp;author=X.%20Zhang&amp;author=X.%20Chen&amp;author=Y.%20Wei\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref152\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib154\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib154\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[154]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">M. Fricker, AM Tolkovsky, V. Borutaite, M. Coleman, GC Brown<\/div>\n<div id=\"ref-id-sbref153\" class=\"title text-m\">\uc2e0\uacbd \uc138\ud3ec \uc0ac\uba78<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ubb3c\ub9ac. Rev., 98(2)(2018), pp. 813-880,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1152\/physrev.00011.2017\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1152\/physrev.00011.2017<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85043579253&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref153\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Neuronal%20cell%20death&amp;publication_year=2018&amp;author=M.%20Fricker&amp;author=A.M.%20Tolkovsky&amp;author=V.%20Borutaite&amp;author=M.%20Coleman&amp;author=G.C.%20Brown\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref153\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib155\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib155\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[155]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">E. Sekerdag, I. Solaroglu, Y. Gursoy-Ozdemir<\/div>\n<div id=\"ref-id-sbref154\" class=\"title text-m\">\ub1cc\uc878\uc911\uc758 \uc138\ud3ec \uc0ac\uba78 \uba54\ucee4\ub2c8\uc998\uacfc \uc0c8\ub85c\uc6b4 \ubd84\uc790 \ubc0f \uc138\ud3ec \uce58\ub8cc \uc635\uc158<\/div>\n<\/div>\n<div class=\"host u-font-sans\">CurrNeuropharmacol, 16 (9) (2018), pp. 1396-1415,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.2174\/1570159X16666180302115544\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.2174\/1570159X16666180302115544<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85052760195&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref154\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Cell%20death%20mechanisms%20in%20stroke%20and%20novel%20molecular%20and%20cellular%20treatment%20options&amp;publication_year=2018&amp;author=E.%20Sekerdag&amp;author=I.%20Solaroglu&amp;author=Y.%20Gursoy-Ozdemir\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref154\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib156\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib156\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[156]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">HL \uc655, QH Zhou, MB Xu, XL Zhou, GQ Zheng<\/div>\n<div id=\"ref-id-sbref155\" class=\"title text-m\">\uc2e4\ud5d8\uc801 \uad6d\uc18c \ub1cc \ud5c8\ud608\uc5d0 \ub300\ud55c \uc544\uc2a4\ud2b8\ub77c\uac08\ub85c\uc0ac\uc774\ub4dc IV: \uc804\uc784\uc0c1 \uc99d\uac70 \ubc0f \uac00\ub2a5\ud55c \uba54\ucee4\ub2c8\uc998<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc0b0\ud654\ubb3c. Med Cell Longev., 2017(2017), \uc870\ud56d 8424326,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1155\/2017\/8424326\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1155\/2017\/8424326<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85016128656&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref155\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Astragaloside%20IV%20for%20experimental%20focal%20cerebral%20ischemia%3A%20preclinical%20evidence%20and%20possible%20mechanisms&amp;publication_year=2017&amp;author=H.L.%20Wang&amp;author=Q.H.%20Zhou&amp;author=M.B.%20Xu&amp;author=X.L.%20Zhou&amp;author=G.Q.%20Zheng\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref155\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib157\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib157\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[157]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">H. \uc790\uc624, Y. \uccb8, H. \ud391<\/div>\n<div id=\"ref-id-sbref156\" class=\"title text-m\">\ucd9c\ud608\uc131 \ub1cc\uc878\uc911\uc758 \ubcd1\ud0dc\uc0dd\ub9ac\ud559\uc5d0\uc11c P2X7 \uc218\uc6a9\uccb4 \uad00\ub828 \ud504\ub85c\uadf8\ub7a8\ud654\ub41c \uc138\ud3ec \uc0ac\uba78<\/div>\n<\/div>\n<div class=\"host u-font-sans\">CurrNeuropharmacol, 16 (9) (2018), pp. 1282-1295,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.2174\/1570159X16666180516094500\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.2174\/1570159X16666180516094500<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85055080474&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref156\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=P2X7%20Receptor-Associated%20Programmed%20Cell%20Death%20in%20the%20Pathophysiology%20of%20Hemorrhagic%20Stroke&amp;publication_year=2018&amp;author=H.%20Zhao&amp;author=Y.%20Chen&amp;author=H.%20Feng\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref156\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib158\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib158\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[158]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">K. \ub450\ub9ac\uc2a4, Z. Splichal, M. Jurajda<\/div>\n<div id=\"ref-id-sbref157\" class=\"title text-m\">\ub1cc\uc878\uc911 \uad00\ub828 \ud504\ub85c\uadf8\ub7a8\ud654\ub41c \uc138\ud3ec \uc0ac\uba78\uc5d0\uc11c \uc5fc\uc99d \ubc18\uc751\uc758 \uc5ed\ud560<\/div>\n<\/div>\n<div class=\"host u-font-sans\">CurrNeuropharmacol, 16 (9) (2018), pp. 1365-1374,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.2174\/1570159X16666180222155833\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.2174\/1570159X16666180222155833<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85055080999&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref157\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20Role%20of%20Inflammatory%20Response%20in%20Stroke%20Associated%20Programmed%20Cell%20Death&amp;publication_year=2018&amp;author=K.%20Duris&amp;author=Z.%20Splichal&amp;author=M.%20Jurajda\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref157\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib159\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib159\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[159]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">DY Fann, EP Nickles, L. Poh, V. Rajeev, S. Selvaraji, H. Schwarz, TV Arumugam<\/div>\n<div id=\"ref-id-sbref158\" class=\"title text-m\">CD137 \ub9ac\uac04\ub4dc-CD137 \uc0c1\ud638\uc791\uc6a9\uc740 \ud5c8\ud608\uc131 \ub1cc\uc878\uc911 \ud6c4 \uc5fc\uc99d\ubcf5\ud569\uccb4 \uad00\ub828 \ub1cc \uc190\uc0c1\uc5d0 \ud544\uc694\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Neuromolecular Med, 22 (4) (2020), pp. 474-483,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1007\/s12017-020-08623-1\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1007\/s12017-020-08623-1<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85092632738&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref158\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=CD137%20Ligand-CD137%20interaction%20is%20required%20for%20inflammasome-associated%20brain%20injury%20following%20ischemic%20stroke&amp;publication_year=2020&amp;author=D.Y.%20Fann&amp;author=E.P.%20Nickles&amp;author=L.%20Poh&amp;author=V.%20Rajeev&amp;author=S.%20Selvaraji&amp;author=H.%20Schwarz&amp;author=T.V.%20Arumugam\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref158\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib160\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib160\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[160]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">V. \ud1a0\ub3c4\ub85c\ud504, M. \ub514\ubbf8\ud2b8\ub85c\ubc14<\/div>\n<div id=\"ref-id-sbref159\" class=\"title text-m\">\ub1cc\uc878\uc911\uacfc \uba74\uc5ed \uccb4\uacc4: \uc0c8\ub85c\uc6b4 \uc804\ub7b5\uc5d0 \ub300\ud55c \uac80\ud1a0<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Folia Med (Plovdiv.), 62 (3) (2020), pp. 431-437,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.3897\/folmed.62.e49451\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.3897\/folmed.62.e49451<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85092679470&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref159\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Stroke%20and%20the%20immune%20system%3A%20a%20review%20of%20the%20new%20strategies&amp;publication_year=2020&amp;author=V.%20Todorov&amp;author=M.%20Dimitrova\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref159\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib161\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib161\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[161]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">FL Yeh, DV Hansen, M. Sheng<\/div>\n<div id=\"ref-id-sbref160\" class=\"title text-m\">TREM2, \uc18c\uad50\uc138\ud3ec \ubc0f \uc2e0\uacbd\ud1f4\ud589\uc131 \uc9c8\ud658<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud2b8\ub80c\ub4dc \ubab0. Med, 23(6)(2017), pp. 512-533,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.molmed.2017.03.008\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.molmed.2017.03.008<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1471491417300473\/pdfft?md5=493d5864859705788e3932a88a92a5b1&amp;pid=1-s2.0-S1471491417300473-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref160\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1471491417300473\" aria-describedby=\"ref-id-sbref160\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85018795527&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref160\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=TREM2%2C%20microglia%2C%20and%20neurodegenerative%20diseases&amp;publication_year=2017&amp;author=F.L.%20Yeh&amp;author=D.V.%20Hansen&amp;author=M.%20Sheng\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref160\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib162\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib162\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[162]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">V. \ucfe0\ub9c8\ub974<\/div>\n<div id=\"ref-id-sbref161\" class=\"title text-m\">\uc2e0\uacbd\uc5fc\uc99d\uc758 \ubc1c\ubcd1\uae30\uc804\uc5d0\uc11c \ud1a8 \uc720\uc0ac \uc218\uc6a9\uccb4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. Neuroimmunol., 332 (2019), pp. 16-30,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.jneuroim.2019.03.012\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.jneuroim.2019.03.012<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S016557281930058X\/pdfft?md5=a4fe2352aa1b05da9ea79a3291e970ec&amp;pid=1-s2.0-S016557281930058X-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref161\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S016557281930058X\" aria-describedby=\"ref-id-sbref161\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85063536274&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref161\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Toll-like%20receptors%20in%20the%20pathogenesis%20of%20neuroinflammation&amp;publication_year=2019&amp;author=V.%20Kumar\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref161\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib163\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib163\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[163]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Z. Zhu, L. Zheng, Y. Li, T. Huang, YC Chao, L. Pan, H. Zhu, Y. Zhao, W. Yu, P. Li<\/div>\n<div id=\"ref-id-sbref162\" class=\"title text-m\">\ud5c8\ud608\uc131 \ub1cc\uc878\uc911 \ud6c4 \uc2e0\uacbd\ud608\uad00 \ubcf5\uad6c\ub97c \uc704\ud55c \uace8\uc218 \uc138\ud3ec\uc758 \uc7a0\uc7ac\uc801\uc778 \uba74\uc5ed\uce58\ub8cc \ud45c\uc801<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Front Neurosci., 13 (2019), p. 758,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.3389\/fnins.2019.00758\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.3389\/fnins.2019.00758<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85070612620&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref162\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Potential%20Immunotherapeutic%20Targets%20on%20Myeloid%20Cells%20for%20Neurovascular%20Repair%20After%20Ischemic%20Stroke&amp;publication_year=2019&amp;author=Z.%20Zhu&amp;author=L.%20Zheng&amp;author=Y.%20Li&amp;author=T.%20Huang&amp;author=Y.C.%20Chao&amp;author=L.%20Pan&amp;author=H.%20Zhu&amp;author=Y.%20Zhao&amp;author=W.%20Yu&amp;author=P.%20Li\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref162\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib164\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib164\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[164]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">DY Fann, YA Lim, YL Cheng, KZ Lok, P. Chunduri, SH Baik, GR Drummond, ST Dheen, CG Sobey, DG Jo, CL Chen, TV Arumugam<\/div>\n<div id=\"ref-id-sbref163\" class=\"title text-m\">NF-\u03baB \ubc0f MAPK \uc2e0\ud638 \uc804\ub2ec\uc774 \ud5c8\ud608\uc131 \ub1cc\uc878\uc911 \ud6c4 \ub274\ub7f0\uc5d0\uc11c NLRP \uc5fc\uc99d\ubcf5\ud569\uccb4 \ud65c\uc131\ud654\ub97c \ucd09\uc9c4\ud55c\ub2e4\ub294 \uc99d\uac70<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ubab0. Neurobiol., 55 (2) (2018), pp. 1082-1096,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1007\/s12035-017-0394-9\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1007\/s12035-017-0394-9<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85009437506&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref163\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Evidence%20that%20NF-B%20and%20MAPK%20Signaling%20Promotes%20NLRP%20Inflammasome%20Activation%20in%20Neurons%20Following%20Ischemic%20Stroke&amp;publication_year=2018&amp;author=D.Y.%20Fann&amp;author=Y.A.%20Lim&amp;author=Y.L.%20Cheng&amp;author=K.Z.%20Lok&amp;author=P.%20Chunduri&amp;author=S.H.%20Baik&amp;author=G.R.%20Drummond&amp;author=S.T.%20Dheen&amp;author=C.G.%20Sobey&amp;author=D.G.%20Jo&amp;author=C.L.%20Chen&amp;author=T.V.%20Arumugam\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref163\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib165\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib165\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[165]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">J. Li, JH Hao, D. Yao, R. Li, XF Li, ZY Yu, X. Luo, XH Liu, MH Wang, W. Wang<\/div>\n<div id=\"ref-id-sbref164\" class=\"title text-m\">Caspase-1 \uc5b5\uc81c\ub294 \ub1cc \ud5c8\ud608\uc758 \uc950 \ubaa8\ub378\uc5d0\uc11c pyroptosis\uc758 \ud45c\uc900 \uc5fc\uc99d\ubcf5\ud569\uccb4 \uacbd\ub85c\ub97c \ud45c\uc801\uc73c\ub85c \uc0bc\uc544 \uc2e0\uacbd \uc138\ud3ec \uc0ac\uba78\uc744 \uc608\ubc29\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">CNS \uc2e0\uacbd\uacfc\ud559. Ther., 26(9)(2020), pp. 925-939,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1111\/cns.13384\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1111\/cns.13384<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85084010416&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref164\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Caspase-1%20inhibition%20prevents%20neuronal%20death%20by%20targeting%20the%20canonical%20inflammasome%20pathway%20of%20pyroptosis%20in%20a%20murine%20model%20of%20cerebral%20ischemia&amp;publication_year=2020&amp;author=J.%20Li&amp;author=J.H.%20Hao&amp;author=D.%20Yao&amp;author=R.%20Li&amp;author=X.F.%20Li&amp;author=Z.Y.%20Yu&amp;author=X.%20Luo&amp;author=X.H.%20Liu&amp;author=M.H.%20Wang&amp;author=W.%20Wang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref164\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib166\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib166\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[166]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">J. Liang, Q. Wang, JQ Li, T. Guo, D. Yu<\/div>\n<div id=\"ref-id-sbref165\" class=\"title text-m\">\uae34 \ube44\ucf54\ub529 RNA MEG3\ub294 miR-485\/AIM2 \ucd95\uc744 \ud45c\uc801\uc73c\ub85c \uc0bc\uc544 \ubc1c\uc5f4\uc99d\uc744 \uc99d\uac00\uc2dc\ucf1c \ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc744 \ucd09\uc9c4\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud2b9\uae09. Neurol., 325 (2020), \uc870\ud56d 113139,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.expneurol.2019.113139\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.expneurol.2019.113139<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0014488619302869\/pdfft?md5=c32009110f4a234e536f16bbd938c229&amp;pid=1-s2.0-S0014488619302869-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref165\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0014488619302869\" aria-describedby=\"ref-id-sbref165\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85076270980&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref165\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Long%20non-coding%20RNA%20MEG3%20promotes%20cerebral%20ischemia-reperfusion%20injury%20through%20increasing%20pyroptosis%20by%20targeting%20miR-485AIM2%20axis&amp;publication_year=2020&amp;author=J.%20Liang&amp;author=Q.%20Wang&amp;author=J.Q.%20Li&amp;author=T.%20Guo&amp;author=D.%20Yu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref165\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib167\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib167\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[167]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">D. \ub85c\uc2dc<\/div>\n<div id=\"ref-id-sbref166\" class=\"title text-m\">\uc131\uc0c1\uad50\uc138\ud3ec \uc0dd\ub9ac\ubcd1\ub9ac\ud559: \uc138\ud3ec\uac04 \ub124\ud2b8\uc6cc\ud0b9, \uc5fc\uc99d \ubc0f \uc138\ud3ec \uc0ac\uba78\uc758 \uad50\ucc28\uc810<\/div>\n<\/div>\n<div class=\"comment\">2015<\/div>\n<div class=\"host u-font-sans\">\uc74c\uc2dd\ubb3c. Neurobiol., 130(2015), pp. 86-120<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0301008215000374\/pdfft?md5=1559dfe9f57d972ab95684120a559165&amp;pid=1-s2.0-S0301008215000374-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref166\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0301008215000374\" aria-describedby=\"ref-id-sbref166\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84931564272&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref166\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Astrocyte%20physiopathology%3A%20At%20the%20crossroads%20of%20intercellular%20networking%2C%20inflammation%20and%20cell%20death&amp;publication_year=2015&amp;author=D.%20Rossi\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref166\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib168\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib168\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[168]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">NR \uc2ec\uc988, WP Yew<\/div>\n<div id=\"ref-id-sbref167\" class=\"title text-m\">\ub1cc\uc878\uc911\uc758 \ubc18\uc751\uc131 \uc131\uc0c1\uad50\uc138\ud3ec\uc99d: \uc2e0\uacbd \uae30\ub2a5 \ud68c\ubcf5\uc5d0 \ub300\ud55c \uc131\uc0c1\uad50\uc138\ud3ec\uc758 \uae30\uc5ec<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Neurochem Int, 107 (2017), pp. 88-103,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.neuint.2016.12.016\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.neuint.2016.12.016<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0197018616303874\/pdfft?md5=7ac67d036f93d7e49973d9f05bd1df1a&amp;pid=1-s2.0-S0197018616303874-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref167\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0197018616303874\" aria-describedby=\"ref-id-sbref167\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85009483754&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref167\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Reactive%20astrogliosis%20in%20stroke%3A%20Contributions%20of%20astrocytes%20to%20recovery%20of%20neurological%20function&amp;publication_year=2017&amp;author=N.R.%20Sims&amp;author=W.P.%20Yew\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref167\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib169\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib169\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[169]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">SL Macauley, M. Pekny, MS \uc0cc\uc988<\/div>\n<div id=\"ref-id-sbref168\" class=\"title text-m\">\uc601\uc544 \uc2e0\uacbd \uc138\ub85c\uc774\ub4dc \ub9ac\ud3ec\ud478\uc2e0\uc99d\uc5d0\uc11c \uc57d\ud654\ub41c \uc131\uc0c1\uad50\uc138\ud3ec \ud65c\uc131\ud654\uc758 \uc5ed\ud560<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. Neurosci., 31 (43) (2011), pp. 15575-15585,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1523\/JNEUROSCI.3579-11.2011\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1523\/JNEUROSCI.3579-11.2011<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-80054910077&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref168\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20role%20of%20attenuated%20astrocyte%20activation%20in%20infantile%20neuronal%20ceroid%20lipofuscinosis&amp;publication_year=2011&amp;author=S.L.%20Macauley&amp;author=M.%20Pekny&amp;author=M.S.%20Sands\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref168\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib170\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib170\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[170]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">BR Barker, DJ Taxman, JP Ting<\/div>\n<div id=\"ref-id-sbref169\" class=\"title text-m\">\uc5fc\uc99d\ubcf5\ud569\uccb4\uc640 \uae30\ud0c0 \uc5fc\uc99d\uc131 \uc0ac\uc774\ud1a0\uce74\uc778\uc744 \ucc98\ub9ac\ud558\ub294 IL-1\u03b2\/IL-18 \uac04\uc758 \uad50\ucc28 \uc870\uc808<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud604\uc7ac \uc758\uacac. Immunol., 23(5)(2011), pp. 591-597,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.coi.2011.07.005\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.coi.2011.07.005<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0952791511000781\/pdfft?md5=0e6bc7b6ed20c8b4763c2aaeedbf4301&amp;pid=1-s2.0-S0952791511000781-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref169\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0952791511000781\" aria-describedby=\"ref-id-sbref169\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-80053589126&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref169\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Cross-regulation%20between%20the%20IL-1IL-18%20processing%20inflammasome%20and%20other%20inflammatory%20cytokines&amp;publication_year=2011&amp;author=B.R.%20Barker&amp;author=D.J.%20Taxman&amp;author=J.P.%20Ting\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref169\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib171\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib171\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[171]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">\uae40\uc9c0\uc640\uc774, \ubc15\uc81c\uc774, \uc7a5\uc9c4\uc601, \uae40\uc0c1\ud604, \uc774\uc7ac\uc774<\/div>\n<div id=\"ref-id-sbref170\" class=\"title text-m\">\ud5c8\ud608\uc131 \ub1cc\uc878\uc911 \ud6c4 \uc5fc\uc99d: \ubc31\ud608\uad6c\uc640 \uc2e0\uacbd\uc544\uad50\uc138\ud3ec\uc758 \uc5ed\ud560<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud2b9\uae09. Neurobiol., 25 (5) (2016), pp. 241-251,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.5607\/en.2016.25.5.241\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.5607\/en.2016.25.5.241<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0043135415303869\/pdfft?md5=f3d6c7c61be8fb0a165ebd91de40fa97&amp;pid=1-s2.0-S0043135415303869-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref170\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0043135415303869\" aria-describedby=\"ref-id-sbref170\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Inflammation%20after%20Ischemic%20Stroke%3A%20The%20Role%20of%20Leukocytes%20and%20Glial%20Cells&amp;publication_year=2016&amp;author=J.Y.%20Kim&amp;author=J.%20Park&amp;author=J.Y.%20Chang&amp;author=S.H.%20Kim&amp;author=J.E.%20Lee\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref170\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib172\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib172\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[172]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">X. Sun, X. Song, L. Zhang, J. Sun, X. Wei, L. Meng, J. An<\/div>\n<div id=\"ref-id-sbref171\" class=\"title text-m\">NLRP2\ub294 \ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc758 \ub9c8\uc6b0\uc2a4 \ubaa8\ub378\uc5d0\uc11c \ub192\uac8c \ubc1c\ud604\ub429\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc0dd\ud654\ud559 \uc0dd\ubb3c\ubb3c\ub9ac\ud559. Res Commun., 479 (4) (2016), pp. 656-662,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.bbrc.2016.09.157\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.bbrc.2016.09.157<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006291X1631631X\/pdfft?md5=b2046ba23c9d2cd802085d3e5ae97f82&amp;pid=1-s2.0-S0006291X1631631X-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref171\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006291X1631631X\" aria-describedby=\"ref-id-sbref171\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84991447101&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref171\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=NLRP2%20is%20highly%20expressed%20in%20a%20mouse%20model%20of%20ischemic%20stroke&amp;publication_year=2016&amp;author=X.%20Sun&amp;author=X.%20Song&amp;author=L.%20Zhang&amp;author=J.%20Sun&amp;author=X.%20Wei&amp;author=L.%20Meng&amp;author=J.%20An\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref171\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib173\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib173\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[173]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">P. An, J. Xie, S. Qiu, Y. Liu, J. Wang, X. Xiu, L. Li, M. Tang<\/div>\n<div id=\"ref-id-sbref172\" class=\"title text-m\">\ud788\ud53c\ub458\ub9b0\uc740 NLRP3 \ub9e4\uac1c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uc5b5\uc81c\ub97c \ud1b5\ud574 \ub1cc\ud5c8\ud608 \uc7ac\uad00\ub958 \uc190\uc0c1\uc5d0 \ub300\ud55c \uc2e0\uacbd\ubcf4\ud638 \ud65c\uc131\uc744 \ub098\ud0c0\ub0c5\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc0dd\uba85\uacfc\ud559, 232(2019), \uc870\ud56d 116599,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.lfs.2019.116599\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.lfs.2019.116599<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0024320519305259\/pdfft?md5=0ff6d213b67a0633229dcc5c0c9f4326&amp;pid=1-s2.0-S0024320519305259-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref172\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0024320519305259\" aria-describedby=\"ref-id-sbref172\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85068738352&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref172\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Hispidulin%20exhibits%20neuroprotective%20activities%20against%20cerebral%20ischemia%20reperfusion%20injury%20through%20suppressing%20NLRP3-mediated%20pyroptosis&amp;publication_year=2019&amp;author=P.%20An&amp;author=J.%20Xie&amp;author=S.%20Qiu&amp;author=Y.%20Liu&amp;author=J.%20Wang&amp;author=X.%20Xiu&amp;author=L.%20Li&amp;author=M.%20Tang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref172\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib174\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib174\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[174]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">C. Meng, J. Zhang, L. Zhang, Y. Wang, Z. Li, J. Zhao<\/div>\n<div id=\"ref-id-sbref173\" class=\"title text-m\">\uc950\uc758 \ub1cc\ud5c8\ud608\/\uc7ac\uad00\ub958(I\/R) \uc190\uc0c1\uc5d0 \ub300\ud55c NLRP6\uc758 \ud6a8\uacfc<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J.Mol. Neurosci., 69 (3) (2019), 411-418\ud398\uc774\uc9c0,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1007\/s12031-019-01370-4\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1007\/s12031-019-01370-4<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85069709852&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref173\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Effects%20of%20NLRP6%20in%20Cerebral%20IschemiaReperfusion%20%20Injury%20in%20Rats&amp;publication_year=2019&amp;author=C.%20Meng&amp;author=J.%20Zhang&amp;author=L.%20Zhang&amp;author=Y.%20Wang&amp;author=Z.%20Li&amp;author=J.%20Zhao\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref173\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib175\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib175\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[175]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">J. Zhang, N. Jiang, L. Zhang, C. Meng, J. Zhao, J. Wu<\/div>\n<div id=\"ref-id-sbref174\" class=\"title text-m\">\uc131\uc0c1\uad50\uc138\ud3ec\uc5d0\uc11c \ubc1c\ud604\ub41c NLRP6\ub294 \uc5fc\uc99d\ubcf5\ud569\uccb4\ub97c \ud65c\uc131\ud654\ud558\uace0 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc720\ub3c4\ud558\uc5ec OGD\/R \ud6c4 \ub274\ub7f0 \uc190\uc0c1\uc744 \uc545\ud654\uc2dc\ud0b5\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Int Immunopharmacol., 80(2020), \uc870\ud56d 106183,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.intimp.2019.106183\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.intimp.2019.106183<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1567576919322349\/pdfft?md5=c1e5a9b7e0dc4f7f764893228f91b305&amp;pid=1-s2.0-S1567576919322349-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref174\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1567576919322349\" aria-describedby=\"ref-id-sbref174\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85077441067&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref174\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=NLRP6%20expressed%20in%20astrocytes%20aggravates%20neurons%20injury%20after%20OGDR%20through%20activating%20the%20inflammasome%20and%20inducing%20pyroptosis&amp;publication_year=2020&amp;author=J.%20Zhang&amp;author=N.%20Jiang&amp;author=L.%20Zhang&amp;author=C.%20Meng&amp;author=J.%20Zhao&amp;author=J.%20Wu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref174\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib176\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib176\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[176]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">L. Lian, Y. Zhang, L. Liu, L. Yang, Y. Cai, J. Zhang, S. Xu<\/div>\n<div id=\"ref-id-sbref175\" class=\"title text-m\">\ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc758 \uc2e0\uacbd\uc5fc\uc99d: Microglia\uc758 MicroRNA \ub9e4\uac1c \ubd84\uadf9\uc5d0 \ucd08\uc810<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc804\uba74 \ubab0. Neurosci., 13 (2021), \uc870\ud56d 612439,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.3389\/fnmol.2020.612439\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.3389\/fnmol.2020.612439<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Neuroinflammation%20in%20Ischemic%20Stroke%3A%20Focus%20on%20MicroRNA-mediated%20Polarization%20of%20Microglia&amp;publication_year=2021&amp;author=L.%20Lian&amp;author=Y.%20Zhang&amp;author=L.%20Liu&amp;author=L.%20Yang&amp;author=Y.%20Cai&amp;author=J.%20Zhang&amp;author=S.%20Xu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref175\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib177\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib177\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[177]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">D. \ud55c, H. \ub9ac\uc6b0, Y. \uac00\uc624<\/div>\n<div id=\"ref-id-sbref176\" class=\"title text-m\">\ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc5d0\uc11c \ub9d0\ucd08 \ub2e8\ud575\uad6c\uc640 \ub300\uc2dd\uc138\ud3ec\uc758 \uc5ed\ud560<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ub274\ub864. Sci., 41(12)(2020), pp. 3589-3607,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1007\/s10072-020-04777-9\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1007\/s10072-020-04777-9<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85091820368&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref176\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20role%20of%20peripheral%20monocytes%20and%20macrophages%20in%20ischemic%20stroke&amp;publication_year=2020&amp;author=D.%20Han&amp;author=H.%20Liu&amp;author=Y.%20Gao\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref176\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib178\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib178\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[178]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">J. Zhang, N. Jiang, L. Zhang, C. Meng, J. Zhao, J. Wu<\/div>\n<div id=\"ref-id-sbref177\" class=\"title text-m\">\uc131\uc0c1\uad50\uc138\ud3ec\uc5d0\uc11c \ubc1c\ud604\ub41c NLRP6\ub294 \uc5fc\uc99d\ubcf5\ud569\uccb4\ub97c \ud65c\uc131\ud654\ud558\uace0 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc720\ub3c4\ud558\uc5ec OGD\/R \ud6c4 \ub274\ub7f0 \uc190\uc0c1\uc744 \uc545\ud654\uc2dc\ud0b5\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Int Immunopharmacol., 80(2020), \uc870\ud56d 106183,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.intimp.2019.106183\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.intimp.2019.106183<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1567576919322349\/pdfft?md5=c1e5a9b7e0dc4f7f764893228f91b305&amp;pid=1-s2.0-S1567576919322349-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref177\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1567576919322349\" aria-describedby=\"ref-id-sbref177\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85077441067&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref177\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=NLRP6%20expressed%20in%20astrocytes%20aggravates%20neurons%20injury%20after%20OGDR%20through%20activating%20the%20inflammasome%20and%20inducing%20pyroptosis&amp;publication_year=2020&amp;author=J.%20Zhang&amp;author=N.%20Jiang&amp;author=L.%20Zhang&amp;author=C.%20Meng&amp;author=J.%20Zhao&amp;author=J.%20Wu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref177\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib179\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib179\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[179]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">L. Poh, SW Kang, SH Baik, GYQ Ng, DT She, P. Balaganapathy, ST Dheen, T. Magnus, M. Gelderblom, CG Sobey, EH Koo, DY Fann, TV Arumugam<\/div>\n<div id=\"ref-id-sbref178\" class=\"title text-m\">NLRC4 \uc778\ud50c\ub77c\ub9c8\uc880\uc774 \ud5c8\ud608\uc131 \ub1cc\uc878\uc911 \ud6c4 \uc138\ud3ec\uc0ac\uba78 \ubc0f \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uc18c\uad50\uc138\ud3ec \uc0ac\ub9dd\uc744 \ub9e4\uac1c\ud55c\ub2e4\ub294 \uc99d\uac70<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ub1cc \ud589\ub3d9. Immun., 75 (2019), pp. 34-47,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.bbi.2018.09.001\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.bbi.2018.09.001<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0889159118305440\/pdfft?md5=7b661aff4cdd3c77552e280ce410df47&amp;pid=1-s2.0-S0889159118305440-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref178\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0889159118305440\" aria-describedby=\"ref-id-sbref178\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85054186635&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref178\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Evidence%20that%20NLRC4%20inflammasome%20mediates%20apoptotic%20and%20pyroptotic%20microglial%20death%20following%20ischemic%20stroke&amp;publication_year=2019&amp;author=L.%20Poh&amp;author=S.W.%20Kang&amp;author=S.H.%20Baik&amp;author=G.Y.Q.%20Ng&amp;author=D.T.%20She&amp;author=P.%20Balaganapathy&amp;author=S.T.%20Dheen&amp;author=T.%20Magnus&amp;author=M.%20Gelderblom&amp;author=C.G.%20Sobey&amp;author=E.H.%20Koo&amp;author=D.Y.%20Fann&amp;author=T.V.%20Arumugam\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref178\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib180\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib180\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[180]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">P. Xu, X. Zhang, Q. Liu, Y. Xie, X. Shi, J. Chen, Y. Li, H. Guo, R. Sun, Y. Hong, X. Liu, G. Xu<\/div>\n<div id=\"ref-id-sbref179\" class=\"title text-m\">\uc18c\uad50\uc138\ud3ec TREM-1 \uc218\uc6a9\uccb4\ub294 \uc2e4\ud5d8\uc801 \ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc5d0\uc11c SYK\uc640\uc758 \uc0c1\ud638\uc791\uc6a9\uc744 \ud1b5\ud574 \uc2e0\uacbd\uc5fc\uc99d\uc131 \uc190\uc0c1\uc744 \ub9e4\uac1c\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Cell Death Dis., 10 (8) (2019), p. 555,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1038\/s41419-019-1777-9\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1038\/s41419-019-1777-9<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85069477703&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref179\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Microglial%20TREM-1%20receptor%20mediates%20neuroinflammatory%20injury%20via%20interaction%20with%20SYK%20in%20experimental%20ischemic%20stroke&amp;publication_year=2019&amp;author=P.%20Xu&amp;author=X.%20Zhang&amp;author=Q.%20Liu&amp;author=Y.%20Xie&amp;author=X.%20Shi&amp;author=J.%20Chen&amp;author=Y.%20Li&amp;author=H.%20Guo&amp;author=R.%20Sun&amp;author=Y.%20Hong&amp;author=X.%20Liu&amp;author=G.%20Xu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref179\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib181\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib181\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[181]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Q. Li, Y. Cao, C. Dang, B. Han, R. Han, H. Ma, J. Hao, L. Wang<\/div>\n<div id=\"ref-id-sbref180\" class=\"title text-m\">\uc774\uc911 \uac00\ub2e5 DNA \uac10\uc9c0 cGAS\uc758 \uc5b5\uc81c\ub294 \ud5c8\ud608\uc131 \ub1cc\uc878\uc911 \ud6c4 \ub1cc \uc190\uc0c1\uc744 \uac1c\uc120\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc5e0\ubcf4 \ubab0. Med, 12 (4) (2020), \uc870\ud56d e11002,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.15252\/emmm.201911002\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.15252\/emm.201911002<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85082767904&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref180\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Inhibition%20of%20double-strand%20DNA-sensing%20cGAS%20ameliorates%20brain%20injury%20after%20ischemic%20stroke&amp;publication_year=2020&amp;author=Q.%20Li&amp;author=Y.%20Cao&amp;author=C.%20Dang&amp;author=B.%20Han&amp;author=R.%20Han&amp;author=H.%20Ma&amp;author=J.%20Hao&amp;author=L.%20Wang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref180\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib182\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib182\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[182]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Y. Zhao, J. Yang, C. Li, G. Zhou, H. Wan, Z. Ding, H. Wan, H. Zhou<\/div>\n<div id=\"ref-id-sbref181\" class=\"title text-m\">\ub1cc\ud5c8\ud608\uc131 \uc190\uc0c1 \uacfc\uc815\uc5d0\uc11c \uc2e0\uacbd\ud608\uad00 \ub2e8\uc704\uc758 \uc5ed\ud560<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc81c\uc57d \uacb0\uc758\uc548, 160(2020), \uc870\ud56d 105103,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.phrs.2020.105103\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.phrs.2020.105103<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1043661820314110\/pdfft?md5=4f8b1536cafaad752162f757d53af334&amp;pid=1-s2.0-S1043661820314110-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref181\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1043661820314110\" aria-describedby=\"ref-id-sbref181\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85089342123&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref181\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Role%20of%20the%20neurovascular%20unit%20in%20the%20process%20of%20cerebral%20ischemic%20injury&amp;publication_year=2020&amp;author=Y.%20Zhao&amp;author=J.%20Yang&amp;author=C.%20Li&amp;author=G.%20Zhou&amp;author=H.%20Wan&amp;author=Z.%20Ding&amp;author=H.%20Wan&amp;author=H.%20Zhou\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref181\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib183\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib183\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[183]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">X. Hu, TM De Silva, J. Chen, FM Faraci<\/div>\n<div id=\"ref-id-sbref182\" class=\"title text-m\">\ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc5d0 \uc788\uc5b4\uc11c\uc758 \ub1cc\ud608\uad00\uc9c8\ud658\uacfc \uc2e0\uacbd\ud608\uad00 \uc190\uc0c1<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc21c\ud658 \uacb0\uc758\uc548, 120(3)(2017), 449-471\ud398\uc774\uc9c0,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1161\/CIRCRESAHA.116.308427\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1161\/CIRCRESAHA.116.308427<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85011827599&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref182\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Cerebral%20Vascular%20Disease%20and%20Neurovascular%20Injury%20in%20Ischemic%20Stroke&amp;publication_year=2017&amp;author=X.%20Hu&amp;author=T.M.%20De%20Silva&amp;author=J.%20Chen&amp;author=F.M.%20Faraci\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref182\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib184\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib184\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[184]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">C. Yang, KE Hawkins, S. Dor\u00e9, E. Candelario-Jalil<\/div>\n<div id=\"ref-id-sbref183\" class=\"title text-m\">\ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc5d0\uc11c \ud608\uc561\ub1cc\uc7a5\ubcbd \uc190\uc0c1\uc758 \uc2e0\uacbd\uc5fc\uc99d \uae30\uc804<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc624\uc804. J. Physiol. \uc138\ud3ec \ubb3c\ub9ac\ud559, 316(2)(2019), \ud398\uc774\uc9c0 C135-C153,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1152\/ajpcell.00136.2018\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1152\/ajpcell.00136.2018<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85060135049&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref183\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Neuroinflammatory%20mechanisms%20of%20blood-brain%20barrier%20damage%20in%20ischemic%20stroke&amp;publication_year=2019&amp;author=C.%20Yang&amp;author=K.E.%20Hawkins&amp;author=S.%20Dor%C3%A9&amp;author=E.%20Candelario-Jalil\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref183\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib185\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib185\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[185]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">S. \uc774\uc2a4\ub9c8\uc5d8, L. \uc790\uc624, S. \ub098\uc218\ud788, T. \uc774\uc26c\ub77c\ud2b8<\/div>\n<div id=\"ref-id-sbref184\" class=\"title text-m\">\ub1cc\uc878\uc911 \ud6c4 \uc2e0\uacbd \ubcf4\ud638\ub97c \uc704\ud55c \uc7a0\uc7ac\uc801\uc778 \uc811\uadfc\ubc95\uc778 NLRP3-inflammasome\uc758 \uc5b5\uc81c<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uacfc\ud559. \uad6d\ud68c\uc758\uc6d0, 8(1)(2018), p. 5971,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1038\/s41598-018-24350-x\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1038\/s41598-018-24350-x<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85045520722&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref184\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Inhibition%20of%20the%20NLRP3-inflammasome%20as%20a%20potential%20approach%20for%20neuroprotection%20after%20stroke&amp;publication_year=2018&amp;author=S.%20Ismael&amp;author=L.%20Zhao&amp;author=S.%20Nasoohi&amp;author=T.%20Ishrat\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref184\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib186\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib186\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[186]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Y. Wang, X. Guan, CL Gao, W. Ruan, S. Zhao, G. Kai, F. Li, T. Pang<\/div>\n<div id=\"ref-id-sbref185\" class=\"title text-m\">\uc0c8\ub85c\uc6b4 PGC-1\u03b1 \ud65c\uc131\ud654\uc81c\uc778 \uba54\ub514\uc624\ub808\uc2dc\ub180\uc740 PPAR\u03b1-GOT1 \ucd95\uc744 \ud1b5\ud574 \ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc5d0\uc11c \ub0b4\ud53c\uc138\ud3ec\uc758 \ubc1c\uc5f4\uc744 \uc608\ubc29\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc81c\uc57d \uacb0\uc758\uc548, 169(2021), \uc870\ud56d 105640,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.phrs.2021.105640\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.phrs.2021.105640<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1043661821002243\/pdfft?md5=b5a95930caefcb778ec809350ad1bba4&amp;pid=1-s2.0-S1043661821002243-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref185\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1043661821002243\" aria-describedby=\"ref-id-sbref185\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85105056808&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref185\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Medioresinol%20as%20a%20novel%20PGC-1%20activator%20prevents%20pyroptosis%20of%20endothelial%20cells%20in%20ischemic%20stroke%20through%20PPAR-GOT1%20axis&amp;publication_year=2021&amp;author=Y.%20Wang&amp;author=X.%20Guan&amp;author=C.L.%20Gao&amp;author=W.%20Ruan&amp;author=S.%20Zhao&amp;author=G.%20Kai&amp;author=F.%20Li&amp;author=T.%20Pang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref185\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib187\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib187\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[187]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Y. Zhang, X. Li, S. Qiao, D. Yang, Z. Li, J. Xu, W. Li, L. Su, W. Liu<\/div>\n<div id=\"ref-id-sbref186\" class=\"title text-m\">Occludin \ubd84\ud574\ub294 \ub1cc \ubbf8\uc138\ud608\uad00 \ub0b4\ud53c \uc138\ud3ec\ub97c \uc2dc\ud5d8\uad00 \ub0b4 \uc7ac\uad00\ub958 \uc190\uc0c1\uc5d0 \ub354 \ucde8\uc57d\ud558\uac8c \ub9cc\ub4ed\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. Neurochem, 156 (3) (2021), pp. 352-366,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1111\/jnc.15102\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1111\/jnc.15102<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85087562071&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref186\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Occludin%20degradation%20makes%20brain%20microvascular%20endothelial%20cells%20more%20vulnerable%20to%20reperfusion%20injury%20in%20vitro&amp;publication_year=2021&amp;author=Y.%20Zhang&amp;author=X.%20Li&amp;author=S.%20Qiao&amp;author=D.%20Yang&amp;author=Z.%20Li&amp;author=J.%20Xu&amp;author=W.%20Li&amp;author=L.%20Su&amp;author=W.%20Liu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref186\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib188\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib188\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[188]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Y. Liang, P. Song, W. Chen, X. Xie, R. Luo, J. Su, Y. Zhu, J. Xu, R. Liu, P. Zhu, Y. Zhang, M. Huang<\/div>\n<div id=\"ref-id-sbref187\" class=\"title text-m\">Caspase-1\uc758 \uc5b5\uc81c\ub294 \ubc1c\uc5f4\uc99d \ud65c\uc131\ud654\ub97c \uc5b5\uc81c\ud568\uc73c\ub85c\uc368 \ud5c8\ud608 \uad00\ub828 \ud608\uc561-\ub1cc \uc7a5\ubcbd \uae30\ub2a5 \uc7a5\uc560 \ubc0f \uc644\uc804\uc131\uc744 \uac1c\uc120\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Front Cell Neurosci., 14 (2021), \uc870\ud56d 540669,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.3389\/fncel.2020.540669\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.3389\/fncel.2020.540669<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Inhibition%20of%20Caspase-1%20Ameliorates%20Ischemia-Associated%20Blood-Brain%20Barrier%20Dysfunction%20and%20Integrity%20by%20Suppressing%20Pyroptosis%20Activation&amp;publication_year=2021&amp;author=Y.%20Liang&amp;author=P.%20Song&amp;author=W.%20Chen&amp;author=X.%20Xie&amp;author=R.%20Luo&amp;author=J.%20Su&amp;author=Y.%20Zhu&amp;author=J.%20Xu&amp;author=R.%20Liu&amp;author=P.%20Zhu&amp;author=Y.%20Zhang&amp;author=M.%20Huang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref187\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib189\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib189\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[189]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Q. \ub9ac, Z. \ub2e4\uc774, Y. \uce74\uc624, L. \uc655<\/div>\n<div id=\"ref-id-sbref188\" class=\"title text-m\">Caspase-1 \uc5b5\uc81c\ub294 M2 \ubbf8\uc138\uc544\uad50\uc138\ud3ec\/\ub300\uc2dd\uc138\ud3ec\ub97c \ubd84\uadf9\ud654\ud558\uace0 NF-\u03baB \ud65c\uc131\ud654\ub97c \uc5b5\uc81c\ud568\uc73c\ub85c\uc368 \uc2e4\ud5d8\uc801 \ub1cc\uc878\uc911\uc5d0\uc11c \uc2e0\uacbd \ubcf4\ud638\ub97c \uc911\uc7ac\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc0dd\ud654\ud559 \uc0dd\ubb3c\ubb3c\ub9ac\ud559. Res Commun., 513 (2) (2019), 479-485\ud398\uc774\uc9c0,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.bbrc.2019.03.202\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.bbrc.2019.03.202<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006291X19306096\/pdfft?md5=2152982b45488e428acd53c08db7d695&amp;pid=1-s2.0-S0006291X19306096-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref188\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006291X19306096\" aria-describedby=\"ref-id-sbref188\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Caspase-1%20inhibition%20mediates%20neuroprotection%20in%20experimental%20stroke%20by%20polarizing%20M2%20microgliamacrophage%20and%20suppressing%20NF-B%20activation&amp;publication_year=2019&amp;author=Q.%20Li&amp;author=Z.%20Dai&amp;author=Y.%20Cao&amp;author=L.%20Wang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref188\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib190\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib190\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[190]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">S. \uc774\uc2a4\ub9c8\uc5d8, L. \uc790\uc624, S. \ub098\uc218\ud788, T. \uc774\uc26c\ub77c\ud2b8<\/div>\n<div id=\"ref-id-sbref189\" class=\"title text-m\">\ub1cc\uc878\uc911 \ud6c4 \uc2e0\uacbd \ubcf4\ud638\ub97c \uc704\ud55c \uc7a0\uc7ac\uc801\uc778 \uc811\uadfc\ubc95\uc778 NLRP3-inflammasome\uc758 \uc5b5\uc81c<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uacfc\ud559. \uad6d\ud68c\uc758\uc6d0, 8(1)(2018), p. 5971,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1038\/s41598-018-24350-x\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1038\/s41598-018-24350-x<\/span><\/a><\/div>\n<div class=\"comment\">PMID: 29654318; PMCID:PMC5899150.<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85045520722&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref189\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Inhibition%20of%20the%20NLRP3-inflammasome%20as%20a%20potential%20approach%20for%20neuroprotection%20after%20stroke&amp;publication_year=2018&amp;author=S.%20Ismael&amp;author=L.%20Zhao&amp;author=S.%20Nasoohi&amp;author=T.%20Ishrat\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref189\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib191\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib191\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[191]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">X. Liu, X. Lv, Z. Liu, M. Zhang, Y. Leng<\/div>\n<div id=\"ref-id-sbref190\" class=\"title text-m\">\uc131\uc0c1 \uc138\ud3ec \uc720\ub798 \uc138\ud3ec\ubc16 \uc18c\ud3ec\uccb4\uc758 MircoRNA-29a\ub294 TP53INP1 \ubc0f NF-\u03baB\/NLRP3 \ucd95\uc744 \ud1b5\ud574 \ub1cc \ud5c8\ud608 \uc7ac\uad00\ub958 \uc190\uc0c1\uc744 \uc5b5\uc81c\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc138\ud3ec \ubab0. Neurobiol., 42 (5) (2022), pp. 1487-1500,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1007\/s10571-021-01040-3\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1007\/s10571-021-01040-3<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85101234736&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref190\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=MircoRNA-29a%20in%20Astrocyte-derived%20Extracellular%20Vesicles%20Suppresses%20Brain%20Ischemia%20Reperfusion%20Injury%20via%20TP53INP1%20and%20the%20NF-BNLRP3%20Axis&amp;publication_year=2022&amp;author=X.%20Liu&amp;author=X.%20Lv&amp;author=Z.%20Liu&amp;author=M.%20Zhang&amp;author=Y.%20Leng\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref190\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib192\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib192\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[192]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">YB Liang, PP Song, YH Zhu, JM Xu, PZ Zhu, RR Liu, YS Zhang<\/div>\n<div id=\"ref-id-sbref191\" class=\"title text-m\">TREM-1\uc744 \ud45c\uc801\uc73c\ub85c \ud558\ub294 LP17\uc740 \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\uc640 \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc5b5\uc81c\ud558\uc5ec \ub1cc \ud5c8\ud608\ub85c \uc778\ud55c \uc2e0\uacbd \uc190\uc0c1\uc744 \uc57d\ud654\uc2dc\ud0b5\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc0dd\ud654\ud559 \uc0dd\ubb3c\ubb3c\ub9ac\ud559. Res Commun., 529 (3) (2020), pp. 554-561,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.bbrc.2020.05.056\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.bbrc.2020.05.056<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006291X20309645\/pdfft?md5=8c05cfaed5cd8eebadcbfbb39e440900&amp;pid=1-s2.0-S0006291X20309645-mainext.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref191\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006291X20309645\" aria-describedby=\"ref-id-sbref191\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85087844924&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref191\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=TREM-1-targeting%20LP17%20attenuates%20cerebral%20ischemia-induced%20neuronal%20injury%20by%20inhibiting%20oxidative%20stress%20and%20pyroptosis&amp;publication_year=2020&amp;author=Y.B.%20Liang&amp;author=P.P.%20Song&amp;author=Y.H.%20Zhu&amp;author=J.M.%20Xu&amp;author=P.Z.%20Zhu&amp;author=R.R.%20Liu&amp;author=Y.S.%20Zhang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref191\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib193\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib193\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[193]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">P. An, J. Xie, S. Qiu, Y. Liu, J. Wang, X. Xiu, L. Li, M. Tang<\/div>\n<div id=\"ref-id-sbref192\" class=\"title text-m\">\ud788\ud53c\ub458\ub9b0\uc740 NLRP3 \ub9e4\uac1c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uc5b5\uc81c\ub97c \ud1b5\ud574 \ub1cc\ud5c8\ud608 \uc7ac\uad00\ub958 \uc190\uc0c1\uc5d0 \ub300\ud55c \uc2e0\uacbd\ubcf4\ud638 \ud65c\uc131\uc744 \ub098\ud0c0\ub0c5\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc0dd\uba85\uacfc\ud559, 232(2019), \uc870\ud56d 116599,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.lfs.2019.116599\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.lfs.2019.116599<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0024320519305259\/pdfft?md5=0ff6d213b67a0633229dcc5c0c9f4326&amp;pid=1-s2.0-S0024320519305259-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref192\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0024320519305259\" aria-describedby=\"ref-id-sbref192\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85068738352&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref192\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Hispidulin%20exhibits%20neuroprotective%20activities%20against%20cerebral%20ischemia%20reperfusion%20injury%20through%20suppressing%20NLRP3-mediated%20pyroptosis&amp;publication_year=2019&amp;author=P.%20An&amp;author=J.%20Xie&amp;author=S.%20Qiu&amp;author=Y.%20Liu&amp;author=J.%20Wang&amp;author=X.%20Xiu&amp;author=L.%20Li&amp;author=M.%20Tang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref192\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib194\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib194\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[194]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">R. Sun, M. Peng, P. Xu, F. Huang, Y. Xie, J. Li, Y. Hong, H. Guo, Q. Liu, W. Zhu<\/div>\n<div id=\"ref-id-sbref193\" class=\"title text-m\">\uc800\ubc00\ub3c4 \uc9c0\uc9c8\ub2e8\ubc31\uc9c8 \uc218\uc6a9\uccb4(LDLR)\ub294 \ub1cc \ud5c8\ud608\/\uc7ac\uad00\ub958 \uc190\uc0c1 \ud6c4 NLRP3 \ub9e4\uac1c \uc2e0\uacbd \uc5f4\ubd84\ud574\uc99d\uc744 \uc870\uc808\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. \uc2e0\uacbd\uc5fc\uc99d., 17 (1) (2020), p. 330,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1186\/s12974-020-01988-x\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1186\/s12974-020-01988-x<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span>\u00a0<\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85095116758&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref193\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Low-density%20lipoprotein%20receptor%20%20regulates%20NLRP3-mediated%20neuronal%20pyroptosis%20following%20cerebral%20ischemiareperfusion%20injury&amp;publication_year=2020&amp;author=R.%20Sun&amp;author=M.%20Peng&amp;author=P.%20Xu&amp;author=F.%20Huang&amp;author=Y.%20Xie&amp;author=J.%20Li&amp;author=Y.%20Hong&amp;author=H.%20Guo&amp;author=Q.%20Liu&amp;author=W.%20Zhu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref193\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib195\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib195\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[195]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Y. Wang, X. Guan, CL Gao, W. Ruan, S. Zhao, G. Kai, F. Li, T. Pang<\/div>\n<div id=\"ref-id-sbref194\" class=\"title text-m\">\uc0c8\ub85c\uc6b4 PGC-1\u03b1 \ud65c\uc131\ud654\uc81c\uc778 \uba54\ub514\uc624\ub808\uc2dc\ub180\uc740 PPAR\u03b1-GOT1 \ucd95\uc744 \ud1b5\ud574 \ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc5d0\uc11c \ub0b4\ud53c\uc138\ud3ec\uc758 \ubc1c\uc5f4\uc744 \uc608\ubc29\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Pharmacol. \uacb0\uc758\uc548, 169(2021), \uc870\ud56d 105640,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.phrs.2021.105640\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.phrs.2021.105640<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1043661821002243\/pdfft?md5=b5a95930caefcb778ec809350ad1bba4&amp;pid=1-s2.0-S1043661821002243-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref194\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1043661821002243\" aria-describedby=\"ref-id-sbref194\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85105056808&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref194\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Medioresinol%20as%20a%20novel%20PGC-1%20activator%20prevents%20pyroptosis%20of%20endothelial%20cells%20in%20ischemic%20stroke%20through%20PPAR-GOT1%20axis&amp;publication_year=2021&amp;author=Y.%20Wang&amp;author=X.%20Guan&amp;author=C.L.%20Gao&amp;author=W.%20Ruan&amp;author=S.%20Zhao&amp;author=G.%20Kai&amp;author=F.%20Li&amp;author=T.%20Pang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref194\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib196\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib196\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[196]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">X. \uce74\uc624, Y. \uc655, L. \uac00\uc624<\/div>\n<div id=\"ref-id-sbref195\" class=\"title text-m\">CHRFAM7A \uacfc\ubc1c\ud604\uc740 NLRP3\/Caspase-1 \uacbd\ub85c\uc5d0 \uc758\ud574 \ub9e4\uac1c\ub418\ub294 \uc18c\uad50\uc138\ud3ec \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4\ub97c \uc5b5\uc81c\ud568\uc73c\ub85c\uc368 \ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc744 \uc57d\ud654\uc2dc\ud0b5\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc5fc\uc99d, 44 (3) (2021), pp. 1023-1034,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1007\/s10753-020-01398-4\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1007\/s10753-020-01398-4<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85099180923&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref195\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=CHRFAM7A%20overexpression%20attenuates%20cerebral%20ischemia-reperfusion%20injury%20via%20inhibiting%20microglia%20pyroptosis%20mediated%20by%20the%20NLRP3Caspase-1%20pathway&amp;publication_year=2021&amp;author=X.%20Cao&amp;author=Y.%20Wang&amp;author=L.%20Gao\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref195\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib197\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib197\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[197]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">LL Tan, XL Jiang, LX Xu, G. Li, CX Feng, X. Ding, B. Sun, ZH Qin, ZB Zhang, X. Feng, M. Li<\/div>\n<div id=\"ref-id-sbref196\" class=\"title text-m\">TP53 \uc720\ubc1c \ud574\ub2f9\uc791\uc6a9 \ubc0f \uc138\ud3ec\uc0ac\uba78 \uc870\uc808\uc81c\ub294 \uc800\uc0b0\uc18c\uc99d\/\ud5c8\ud608 \uc720\ubc1c \uc18c\uad50\uc138\ud3ec \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \ubc0f \ud5c8\ud608\uc131 \ub1cc \uc190\uc0c1\uc744 \uc644\ud654\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc2e0\uacbd \uc7ac\uc0dd. \uacb0\uc758\uc548, 16(6)(2021), pp. 1037-1043,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.4103\/1673-5374.300453\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.4103\/1673-5374.300453<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85097393831&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref196\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=TP53-induced%20glycolysis%20and%20apoptosis%20regulator%20alleviates%20hypoxiaischemia-induced%20microglial%20pyroptosis%20and%20ischemic%20brain%20damage&amp;publication_year=2021&amp;author=L.L.%20Tan&amp;author=X.L.%20Jiang&amp;author=L.X.%20Xu&amp;author=G.%20Li&amp;author=C.X.%20Feng&amp;author=X.%20Ding&amp;author=B.%20Sun&amp;author=Z.H.%20Qin&amp;author=Z.B.%20Zhang&amp;author=X.%20Feng&amp;author=M.%20Li\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref196\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib198\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib198\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[198]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">X. Liu, M. Zhang, H. Liu, R. Zhu, H. He, Y. Zhou, Y. Zhang, C. Li, D. Liang, Q. Zeng, G. Huang<\/div>\n<div id=\"ref-id-sbref197\" class=\"title text-m\">\uace8\uc218 \uc911\uac04\uc5fd \uc904\uae30\uc138\ud3ec \uc720\ub798 \uc5d1\uc18c\uc880\uc740 \uc18c\uad50\uc138\ud3ec M1\/M2 \ud45c\ud604\ud615\uc744 \uc870\uc808\ud558\uc5ec \ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc73c\ub85c \uc778\ud55c \uc2e0\uacbd\uc5fc\uc99d \ubc0f \ubc1c\uc5f4\uc99d\uc744 \uc57d\ud654\uc2dc\ud0b5\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud2b9\uae09. Neurol., 341(2021), \uc870\ud56d 113700,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.expneurol.2021.113700\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.expneurol.2021.113700<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0014488621001059\/pdfft?md5=9f920b818b5043349105718ac846350b&amp;pid=1-s2.0-S0014488621001059-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref197\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0014488621001059\" aria-describedby=\"ref-id-sbref197\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85104107847&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref197\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Bone%20marrow%20mesenchymal%20stem%20cell-derived%20exosomes%20attenuate%20cerebral%20ischemia-reperfusion%20injury-induced%20neuroinflammation%20and%20pyroptosis%20by%20modulating%20microglia%20M1M2%20phenotypes&amp;publication_year=2021&amp;author=X.%20Liu&amp;author=M.%20Zhang&amp;author=H.%20Liu&amp;author=R.%20Zhu&amp;author=H.%20He&amp;author=Y.%20Zhou&amp;author=Y.%20Zhang&amp;author=C.%20Li&amp;author=D.%20Liang&amp;author=Q.%20Zeng&amp;author=G.%20Huang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref197\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib199\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib199\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[199]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Y. Huang, F. Tan, Y. Zhuo, J. Liu, J. He, D. Duan, M. Lu, Z. Hu<\/div>\n<div id=\"ref-id-sbref198\" class=\"title text-m\">\uc800\uc0b0\uc18c\uc99d\uc774 \uc804\uc81c\ub41c \ud6c4\uac01 \uc810\ub9c9 \uc911\uac04\uc5fd \uc904\uae30 \uc138\ud3ec\ub294 HIF-1\u03b1\ub97c \ud65c\uc131\ud654\ud558\uc5ec \ub1cc \ud5c8\ud608\/\uc7ac\uad00\ub958\uc5d0 \uc758\ud574 \uc720\ubc1c\ub41c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \ubc0f \uc18c\uad50\uc138\ud3ec\uc758 \uc138\ud3ec\uc0ac\uba78\uc744 \ud3d0\uc9c0\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ub178\ud654(Albany NY), 12 (11) (2020), \ud398\uc774\uc9c0 10931-10950,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.18632\/aging.103307\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.18632\/aging.103307<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85087096885&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref198\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Hypoxia-preconditioned%20olfactory%20mucosa%20mesenchymal%20stem%20cells%20abolish%20cerebral%20ischemiareperfusion-induced%20pyroptosis%20and%20apoptotic%20death%20of%20microglial%20cells%20by%20activating%20HIF-1&amp;publication_year=2020&amp;author=Y.%20Huang&amp;author=F.%20Tan&amp;author=Y.%20Zhuo&amp;author=J.%20Liu&amp;author=J.%20He&amp;author=D.%20Duan&amp;author=M.%20Lu&amp;author=Z.%20Hu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref198\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib200\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib200\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[200]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Z. Peng, S. Wang, G. Chen, M. Cai, R. Liu, J. Deng, J. Liu, T. Zhang, Q. Tan, C. Hai<\/div>\n<div id=\"ref-id-sbref199\" class=\"title text-m\">Gastrodin\uc740 \ud56d\uc0b0\ud654 \ubc0f \ud56d\uc5fc\uc99d \ud65c\ub3d9\uc744 \uac1c\uc120\ud558\uace0 \uc138\ud3ec \uc0ac\uba78 \uacbd\ub85c\ub97c \uc5b5\uc81c\ud558\uc5ec \uc0dd\uc950\uc758 \ub1cc \ud5c8\ud608\uc131 \uc190\uc0c1\uc744 \uc644\ud654\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Neurochem Res., 40 (4) (2015), pp. 661-673,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1007\/s11064-015-1513-5\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1007\/s11064-015-1513-5<\/span><\/a><\/div>\n<div class=\"comment\">Epub 2015 1\uc6d4 13\uc77c. PMID: 25582916<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84939992728&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref199\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Gastrodin%20alleviates%20cerebral%20ischemic%20damage%20in%20mice%20by%20improving%20anti-oxidant%20and%20anti-inflammation%20activities%20and%20inhibiting%20apoptosis%20pathway&amp;publication_year=2015&amp;author=Z.%20Peng&amp;author=S.%20Wang&amp;author=G.%20Chen&amp;author=M.%20Cai&amp;author=R.%20Liu&amp;author=J.%20Deng&amp;author=J.%20Liu&amp;author=T.%20Zhang&amp;author=Q.%20Tan&amp;author=C.%20Hai\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref199\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib201\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib201\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[201]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Z. Peng, S. Wang, G. Chen, M. Cai, R. Liu, J. Deng, J. Liu, T. Zhang, Q. Tan, C. Hai<\/div>\n<div id=\"ref-id-sbref200\" class=\"title text-m\">Gastrodin\uc740 \ud56d\uc0b0\ud654 \ubc0f \ud56d\uc5fc\uc99d \ud65c\ub3d9\uc744 \uac1c\uc120\ud558\uace0 \uc138\ud3ec \uc0ac\uba78 \uacbd\ub85c\ub97c \uc5b5\uc81c\ud558\uc5ec \uc0dd\uc950\uc758 \ub1cc \ud5c8\ud608\uc131 \uc190\uc0c1\uc744 \uc644\ud654\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Neurochem Res, 40(4)(2015), pp. 661-673,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1007\/s11064-015-1513-5\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1007\/s11064-015-1513-5<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84939992728&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref200\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Gastrodin%20alleviates%20cerebral%20ischemic%20damage%20in%20mice%20by%20improving%20anti-oxidant%20and%20anti-inflammation%20activities%20and%20inhibiting%20apoptosis%20pathway&amp;publication_year=2015&amp;author=Z.%20Peng&amp;author=S.%20Wang&amp;author=G.%20Chen&amp;author=M.%20Cai&amp;author=R.%20Liu&amp;author=J.%20Deng&amp;author=J.%20Liu&amp;author=T.%20Zhang&amp;author=Q.%20Tan&amp;author=C.%20Hai\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref200\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib202\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib202\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[202]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">S. Li, L. Bian, X. Fu, Q. Ai, Y. Sui, A. Zhang, H. Gao, L. Zhong, D. Lu<\/div>\n<div id=\"ref-id-sbref201\" class=\"title text-m\">Gastrodin \uc804\ucc98\ub9ac\ub294 \ub1cc \ud5c8\ud608\uc131 \uc7ac\uad00\ub958\ub85c \uc778\ud55c \uc950\uc758 \ub1cc \uc190\uc0c1\uc744 \uc644\ud654\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Brain Res, 1712 (2019), pp. 207-216,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.brainres.2019.02.006\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.brainres.2019.02.006<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006899319300824\/pdfft?md5=0a55a8fe45ec7eba3279912710fb2dc1&amp;pid=1-s2.0-S0006899319300824-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref201\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006899319300824\" aria-describedby=\"ref-id-sbref201\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85061816949&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref201\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Gastrodin%20pretreatment%20alleviates%20rat%20brain%20injury%20caused%20by%20cerebral%20ischemic-reperfusion&amp;publication_year=2019&amp;author=S.%20Li&amp;author=L.%20Bian&amp;author=X.%20Fu&amp;author=Q.%20Ai&amp;author=Y.%20Sui&amp;author=A.%20Zhang&amp;author=H.%20Gao&amp;author=L.%20Zhong&amp;author=D.%20Lu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref201\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib203\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib203\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[203]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">W. Sun, H. Lu, L. Lyu, P. Yang, Z. Lin, L. Li, L. Sun, D. Lu<\/div>\n<div id=\"ref-id-sbref202\" class=\"title text-m\">Gastrodin\uc740 NLRP3\/caspase-1 \uacbd\ub85c\ub97c \uc870\uc808\ud558\uc5ec \ubbf8\uc138\ud608\uad00 \uc7ac\uad00\ub958 \uc190\uc0c1\uc73c\ub85c \uc778\ud55c \ubc1c\uc5f4\uc99d\uc744 \uac1c\uc120\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. Physiol. Biochem, 75 (4) (2019), pp. 531-547,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1007\/s13105-019-00702-7\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1007\/s13105-019-00702-7<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85071480099&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref202\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Gastrodin%20ameliorates%20microvascular%20reperfusion%20injury-induced%20pyroptosis%20by%20regulating%20the%20NLRP3caspase-1%20pathway&amp;publication_year=2019&amp;author=W.%20Sun&amp;author=H.%20Lu&amp;author=L.%20Lyu&amp;author=P.%20Yang&amp;author=Z.%20Lin&amp;author=L.%20Li&amp;author=L.%20Sun&amp;author=D.%20Lu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref202\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib204\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib204\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[204]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">HS Zhang, B. Ouyang, XY Ji, MF Liu<\/div>\n<div id=\"ref-id-sbref203\" class=\"title text-m\">Gastrodin\uc740 lncRNA NEAT1\/miR-22-3p \ucd95\uc744 \uc870\uc808\ud558\uc5ec Pyroptosis\ub97c \uc5b5\uc81c\ud558\uc5ec \ub1cc \ud5c8\ud608\/\uc7ac\uad00\ub958 \uc190\uc0c1\uc744 \uc644\ud654\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Neurochem Res, 46 (7) (2021), pp. 1747-1758,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1007\/s11064-021-03285-2\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1007\/s11064-021-03285-2<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85104117182&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref203\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Gastrodin%20Alleviates%20Cerebral%20IschaemiaReperfusion%20Injury%20by%20Inhibiting%20Pyroptosis%20by%20Regulating%20the%20lncRNA%20NEAT1miR-22-3p%20Axis&amp;publication_year=2021&amp;author=H.S.%20Zhang&amp;author=B.%20Ouyang&amp;author=X.Y.%20Ji&amp;author=M.F.%20Liu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref203\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib205\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib205\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[205]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">\uce74\uc774 \ub9b0<\/div>\n<div id=\"ref-id-sbref204\" class=\"title text-m\">\uc774\uc0e4\uc624\ubcf4. Yuan Libanget al. NL RP3 \uc5fc\uc99d\ubcf5\ud569\uccb4 \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub97c \ud1b5\ud55c \ud3ec\ub3c4\ub2f9-\uc0b0\uc18c \uacb0\ud54d\/\uc7ac\uad00\ub958 \uc190\uc0c1\uc73c\ub85c \uc778\ud55c \ubbf8\uc138\uc544\uad50\uc138\ud3ec\uc5d0 \ub300\ud55c \ud0c4\uc2dc\ub17c IIA\uc758 \ubcf4\ud638 \ud6a8\uacfc<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. \uc4f0\ucd28 \ub300\ud559\uad50 (Med. Ed.), 47(5)(2016), pp. 660-664<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85142895056&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref204\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Yi%20Xiaobo.%20Yuan%20Libang%20et%20al.%20Protective%20effect%20of%20tanshinone%20IIA%20on%20microglia%20from%20glucose-oxygen%20deprivationreperfusion%20injury%20via%20the%20NL%20RP3%20inflammasome%20signaling%20pathway&amp;publication_year=2016&amp;author=Cai%20Lin\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref204\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib206\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib206\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[206]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">\uc815\uc988\uc954, \uc655\uc174\uc789, \ub7c9\ud718<\/div>\n<div id=\"ref-id-sbref205\" class=\"title text-m\">\ub9cc\uc131 \ub1cc\ud5c8\ud608\uc774 \uc788\ub294 \uc950\uc758 \uc778\uc9c0 \uae30\ub2a5\uc5d0 \ub300\ud55c \ub808\uc624\ub204\ub9b0\uc758 \ud6a8\uacfc<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud131. \uac00\ubccd\uac8c \ub450\ub4dc\ub9ac\uae30. Med., 40(9)(2018), pp. 2045-2048<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Effects%20of%20Leonurine%20on%20cognitive%20function%20in%20rats%20with%20chronic%20cerebral%20ischemia&amp;publication_year=2018&amp;author=Zheng%20Zhijun&amp;author=Wang%20Xianying&amp;author=Liang%20Hui\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref205\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib207\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib207\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[207]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">\uc655\ud6d9\ucde8\uc548, \uc794\uc9c0\uc5d0<\/div>\n<div id=\"ref-id-sbref206\" class=\"title text-m\">\ub958\ub9c8\ud2f0\uc2a4 \uad00\uc808\uc5fc \uce58\ub8cc\uc5d0 \uc788\uc5b4\uc11c \uc791\uc57d\uc758 \ucd1d\uae00\ub8e8\ucf54\uc0ac\uc774\ub4dc\uc758 \uc57d\ub9ac\ud559\uc801 \ud6a8\uacfc \ubc0f \uae30\uc804<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uba54\ub4dc. Her., 34(2)(2015), pp. 199-201<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Pharmacological%20effects%20and%20mechanisms%20of%20total%20glucosides%20of%20paeony%20in%20the%20treatment%20of%20rheumatoid%20arthritis&amp;publication_year=2015&amp;author=Wang%20Hongquan&amp;author=Zhan%20Jie\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref206\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib208\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib208\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[208]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Xiong Zhe, Xie Jiaxuan, Zhu Kunbo,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref207\" class=\"title text-m\">Paeoniflorin\uc740 \uc0b0\uc5d0 \ubbfc\uac10\ud55c \uc774\uc628 \ucc44\ub110\uc744 \uc870\uc808\ud558\uc5ec \uc9c4\ud1b5 \ud6a8\uacfc\ub97c \ubc1c\ud718\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uba54\ub4dc. Her., 38(11)(2019), pp. 1403-1407<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Paeoniflorin%20regulates%20acid-sensitive%20ion%20channels%20to%20exert%20analgesic%20effect&amp;publication_year=2019&amp;author=Xiong%20Zhe&amp;author=Xie%20Jiaxuan&amp;author=Zhu%20Kunbo\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref207\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib209\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib209\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[209]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Zulifiya Aikemu, Mai Hepureti Wupuer, Xing Huihui, Fan Mingxin, Zhang Junjiang<\/div>\n<div id=\"ref-id-sbref208\" class=\"title text-m\">\uae09\uc131 \ub1cc\uacbd\uc0c9 \uc950\uc758 \uc18c\uad50\uc138\ud3ec \ud65c\uc131\ud654\uc5d0 \uc758\ud574 \uc870\uc808\ub418\ub294 \uc2e0\uacbd \ubc1c\uc5f4\uc99d\uc5d0 \ub300\ud55c paeoniflorin\uc758 \ud6a8\uacfc<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. Brain Neurol. Dis., 29(08)(2021), pp. 469-474<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20effect%20of%20paeoniflorin%20on%20neuronal%20pyroptosis%20regulated%20by%20microglia%20activation%20in%20rats%20with%20acute%20cerebral%20infarction&amp;publication_year=2021&amp;author=Zulifiya%20Aikemu&amp;author=Mai%20Hepureti%20Wupuer&amp;author=Xing%20Huihui&amp;author=Fan%20Mingxin&amp;author=Zhang%20Junjiang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref208\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib210\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib210\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[210]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">\uc7a5\uc6e8\uc774, \ub9c8\uc9d5\ud551<\/div>\n<div id=\"ref-id-sbref209\" class=\"title text-m\">NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4 \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub97c \ud1b5\ud574 \uc950\uc758 \ub1cc \ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1 \ud6c4 \uc138\ud3ec \ubc1c\uc5f4\uc99d\uc5d0 \ub300\ud55c \ubd80\ud2f8\ud504\ud0c8\ub77c\uc774\ub4dc\uc758 \ud6a8\uacfc<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. \ud1b5\ud569. \ud131. \uc11c\ucabd. \uba54\ub4dc. \uc2ec\ud608\uad00. \ub1cc\ud608\uad00. Dis., 18(06)(2020), pp. 898-902<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Effects%20of%20butylphthalide%20on%20cell%20pyroptosis%20after%20cerebral%20ischemia-reperfusion%20injury%20in%20rats%20via%20NLRP3%20inflammasome%20signaling%20pathway&amp;publication_year=2020&amp;author=Zhang%20Wei&amp;author=Ma%20Jingping\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref209\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib211\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib211\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[211]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Wang Shaohua, Sun Fanfan, Xue Wei, Jiang Qin, Dong Liuyi Breviscapine<\/div>\n<div id=\"ref-id-sbref210\" class=\"title text-m\">\ub9cc\uc131 \ub1cc \ud5c8\ud608\uc774 \uc788\ub294 \uc950\uc5d0\uc11c NLRP3 \uc778\ud50c\ub77c\ub9c8\uc880 \ud65c\uc131\ud654\ub97c \uc870\uc808\ud558\uace0 \uc2e0\uacbd \uc138\ud3ec\uc758 \ubc1c\uc5f4 \ubc0f \uc138\ud3ec\uc0ac\uba78\uc744 \uc5b5\uc81c\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. Anhui Med. Univ., 55 (09) (2020), pp. 1321-1326,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.19405\/j.cnki.issn1000-1492.2020.09.002\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.19405\/j.cnki.issn1000-1492.2020.09.002<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=regulates%20NLRP3%20inflammasome%20activation%20and%20inhibits%20neuronal%20pyroptosis%20and%20apoptosis%20in%20rats%20with%20chronic%20cerebral%20ischemia&amp;publication_year=2020&amp;author=Wang%20Shaohua&amp;author=Sun%20Fanfan&amp;author=Xue%20Wei&amp;author=Jiang%20Qin&amp;author=Dong%20Liuyi%20Breviscapine\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref210\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib212\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib212\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[212]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">\uc190\uc720\uc9c0\uc5d0, \uc7a5\ub09c\ub09c, \uc870\uba4d<\/div>\n<div id=\"ref-id-sbref211\" class=\"title text-m\">\uc950\uc758 \ub1cc \uc870\uc9c1\uc5d0\uc11c \ud5c8\ud608-\uc7ac\uad00\ub958 \uc911 \uc138\ud3ec \ubc1c\uc5f4\uc99d\uc5d0 \ub300\ud55c \ub808\uc2a4\ubca0\ub77c\ud2b8\ub864\uc758 \uc870\uc808 \ud6a8\uacfc\uc640 \uc18c\uad50\uc138\ud3ec NLRP3 \uc778\ud50c\ub77c\ub9c8\uc19c, Caspase-1 \ubc0f ZO-1\uc5d0 \ub300\ud55c \ud6a8\uacfc<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. \ud558\uc774\ub09c \uba54\ub4dc. Coll., 25(17)(2019), pp. 1291-1294,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.13210\/j.cnki.jhmu.20190716.002\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.13210\/j.cnki.jhmu.20190716.002<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20regulatory%20effect%20of%20resveratrol%20on%20cell%20pyroptosis%20during%20ischemia-reperfusion%20in%20rat%20brain%20tissue%20and%20its%20effects%20on%20microglia%20NLRP3%20inflammasome%2C%20Caspase-1%20and%20ZO-1&amp;publication_year=2019&amp;author=Sun%20Yujie&amp;author=Zhang%20Nannan&amp;author=Zhao%20Meng\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref211\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib213\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib213\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[213]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">DC Ma, NN Zhang, YN Zhang, HS Chen<\/div>\n<div id=\"ref-id-sbref212\" class=\"title text-m\">\uc8fc\uc0ac\uc6a9 \uc0b4\ube44\uc544\ub180\uc0b0\uc740 M1\/M2 \ud45c\ud604\ud615\uc744 \uc804\ud658\ud558\uace0 \uc0dd\uccb4 \ub0b4 \ubc0f \uc2dc\ud5d8\uad00 \ub0b4 \uc18c\uad50\uc138\ud3ec\uc5d0\uc11c NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4\/\ud654\ub18d\uc99d \ucd95\uc744 \uc5b5\uc81c\ud558\uc5ec \ub1cc \ud5c8\ud608\/\uc7ac\uad00\ub958 \uc190\uc0c1\uc744 \uc644\ud654\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. Ethnopharmacol., 270(2021), \uc870\ud56d 113776,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.jep.2021.113776\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.jep.2021.113776<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0378874121000027\/pdfft?md5=c27ebe26e91dd8eb1eb175405c9de391&amp;pid=1-s2.0-S0378874121000027-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref212\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0378874121000027\" aria-describedby=\"ref-id-sbref212\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85099133521&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref212\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Salvianolic%20Acids%20for%20Injection%20alleviates%20cerebral%20ischemiareperfusion%20injury%20by%20switching%20M1M2%20phenotypes%20and%20inhibiting%20NLRP3%20inflammasomepyroptosis%20axis%20in%20microglia%20in%20vivo%20and%20in%20vitro&amp;publication_year=2021&amp;author=D.C.%20Ma&amp;author=N.N.%20Zhang&amp;author=Y.N.%20Zhang&amp;author=H.S.%20Chen\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref212\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib214\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib214\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[214]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">P. An, J. Xie, S. Qiu, Y. Liu, J. Wang, X. Xiu, L. Li, M. Tang<\/div>\n<div id=\"ref-id-sbref213\" class=\"title text-m\">\ud788\ud53c\ub458\ub9b0\uc740 NLRP3 \ub9e4\uac1c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uc5b5\uc81c\ub97c \ud1b5\ud574 \ub1cc\ud5c8\ud608 \uc7ac\uad00\ub958 \uc190\uc0c1\uc5d0 \ub300\ud55c \uc2e0\uacbd\ubcf4\ud638 \ud65c\uc131\uc744 \ub098\ud0c0\ub0c5\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc0dd\uba85\uacfc\ud559, 232(2019), \uc870\ud56d 116599,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.lfs.2019.116599\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.lfs.2019.116599<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0024320519305259\/pdfft?md5=0ff6d213b67a0633229dcc5c0c9f4326&amp;pid=1-s2.0-S0024320519305259-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref213\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0024320519305259\" aria-describedby=\"ref-id-sbref213\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85068738352&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref213\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Hispidulin%20exhibits%20neuroprotective%20activities%20against%20cerebral%20ischemia%20reperfusion%20injury%20through%20suppressing%20NLRP3-mediated%20pyroptosis&amp;publication_year=2019&amp;author=P.%20An&amp;author=J.%20Xie&amp;author=S.%20Qiu&amp;author=Y.%20Liu&amp;author=J.%20Wang&amp;author=X.%20Xiu&amp;author=L.%20Li&amp;author=M.%20Tang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref213\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib215\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib215\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[215]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">J. \uc7a5, C. \uc6b0, L. Gao, G. Du, X. Qin<\/div>\n<div id=\"ref-id-sbref214\" class=\"title text-m\">\ud669\uae30 \uc720\ub798 \ud669\uae30 IV: \uc57d\ub9ac\ud559\uc801 \ud6a8\uacfc\uc5d0 \uad00\ud55c \uc5f0\uad6c \uace0\ucc30<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uace0\uae09 Pharmacol., 87(2020), \ud398\uc774\uc9c0 89-112,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/bs.apha.2019.08.002\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/bs.apha.2019.08.002<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S105435891930064X\/pdfft?md5=7ea17039fd4f6c067b318c0ea6c11e1a&amp;pid=1-s2.0-S105435891930064X-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref214\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S105435891930064X\" aria-describedby=\"ref-id-sbref214\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85076859806&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref214\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Astragaloside%20IV%20derived%20from%20Astragalus%20membranaceus%3A%20a%20research%20review%20on%20the%20pharmacological%20effects&amp;publication_year=2020&amp;author=J.%20Zhang&amp;author=C.%20Wu&amp;author=L.%20Gao&amp;author=G.%20Du&amp;author=X.%20Qin\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref214\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib216\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib216\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[216]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Y. Zang, J. Wan, Z. Zhang, S. Huang, X. Liu, W. Zhang<\/div>\n<div id=\"ref-id-sbref215\" class=\"title text-m\">\uc2ec\ubd80\uc804\uc5d0\uc11c \uc544\uc2a4\ud2b8\ub77c\uac08\ub85c\uc0ac\uc774\ub4dc IV\uc758 \uc5c5\ub370\uc774\ud2b8\ub41c \uc5ed\ud560<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ubc14\uc774\uc624\uba54\ub4dc. Pharm., 126 (2020), \uc870\ud56d 110012,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.biopha.2020.110012\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.biopha.2020.110012<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332220302031\/pdfft?md5=8632e006f059e338e60a04824b2c69fc&amp;pid=1-s2.0-S0753332220302031-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref215\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332220302031\" aria-describedby=\"ref-id-sbref215\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85081961699&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref215\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=An%20updated%20role%20of%20astragaloside%20IV%20in%20heart%20failure&amp;publication_year=2020&amp;author=Y.%20Zang&amp;author=J.%20Wan&amp;author=Z.%20Zhang&amp;author=S.%20Huang&amp;author=X.%20Liu&amp;author=W.%20Zhang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref215\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib217\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib217\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[217]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">T. Chen, P. Yang, Y. Jia<\/div>\n<div id=\"ref-id-sbref216\" class=\"title text-m\">\uc554 \uce58\ub8cc\uc5d0\uc11c \uc544\uc2a4\ud2b8\ub77c\uac08\ub85c\uc0ac\uc774\ub4dc IV\uc758 \ubd84\uc790 \uba54\ucee4\ub2c8\uc998(\uac80\ud1a0)<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Int J. Mol. Med, 47(3)(2021), p. 13,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.3892\/ijmm.2021.4846\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.3892\/ijmm.2021.4846<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Molecular%20mechanisms%20of%20astragaloside%20IV%20in%20cancer%20therapy%20&amp;publication_year=2021&amp;author=T.%20Chen&amp;author=P.%20Yang&amp;author=Y.%20Jia\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref216\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib218\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib218\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[218]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">YQ Tan, HW Chen, J. Li, IV \uc544\uc2a4\ud2b8\ub77c\uac08\ub85c\uc0ac\uc774\ub4dc<\/div>\n<div id=\"ref-id-sbref217\" class=\"title text-m\">\uc2ec\ud608\uad00 \uc9c8\ud658 \uce58\ub8cc\uc5d0 \ud6a8\uacfc\uc801\uc778 \uc57d\ubb3c<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc57d\ubb3c Des. DevelTher, 14 (2020), pp. 3731-3746,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.2147\/DDDT.S272355\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.2147\/DDDT.S272355<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\">\n<p><a class=\"es-link found icon-small\" target=\"_blank\" rel=\"noopener\">\u00a0<span class=\"text\">PDF \ubcf4\uae30<\/span><\/a><\/p>\n<div class=\"tooltip-container left\">\n<div class=\"icon\"><\/div>\n<p class=\"message\">\uc774 \uae00\uc740 \ubb34\ub8cc\ub85c \ubcf4\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<\/div>\n<\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85090878978&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref217\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=An%20effective%20drug%20for%20the%20treatment%20of%20cardiovascular%20diseases&amp;publication_year=2020&amp;author=Y.Q.%20Tan&amp;author=H.W.%20Chen&amp;author=J.%20Li&amp;author=I.V.%20Astragaloside\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref217\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib219\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib219\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[219]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">A. Datta, D. Sarmah, L. Mounica, H. Kaur, R. Kesharwani, G. Verma, P. Veeresh, V. Kotian, K. Kalia, A. Borah, X. Wang, KR Dave, DR Yavagal, P. \ubc14\ud0c0\ucc28\ub9ac\uc57c<\/div>\n<div id=\"ref-id-sbref218\" class=\"title text-m\">\ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uacfc \ud45c\uc801 \uc57d\ubb3c\uc694\ubc95\uc758 \uc138\ud3ec \uc0ac\uba78 \uacbd\ub85c<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ubc88\uc5ed. \ub1cc\uc878\uc911 \ud574\uacb0, 11 (6) (2020), pp. 1185-1202,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1007\/s12975-020-00806-z\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1007\/s12975-020-00806-z<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85082940881&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref218\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Cell%20death%20pathways%20in%20ischemic%20stroke%20and%20targeted%20pharmacotherapy&amp;publication_year=2020&amp;author=A.%20Datta&amp;author=D.%20Sarmah&amp;author=L.%20Mounica&amp;author=H.%20Kaur&amp;author=R.%20Kesharwani&amp;author=G.%20Verma&amp;author=P.%20Veeresh&amp;author=V.%20Kotian&amp;author=K.%20Kalia&amp;author=A.%20Borah&amp;author=X.%20Wang&amp;author=K.R.%20Dave&amp;author=D.R.%20Yavagal&amp;author=P.%20Bhattacharya\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref218\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib220\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib220\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[220]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">K. Yang, L. Zeng, A. Ge, Y. Chen, S. Wang, X. Zhu, J. Ge<\/div>\n<div id=\"ref-id-sbref219\" class=\"title text-m\">HedysarumMultijugumMaxim.-Chuanxiong Rhizoma \ud654\ud569\ubb3c\uc758 HIF-VEGF \uacbd\ub85c \uc870\uc808 \uba54\ucee4\ub2c8\uc998\uacfc \ub1cc\ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc758 \uccb4\uacc4\uc801\uc778 \uc57d\ub9ac\ud559 \uae30\ubc18 \uc0dd\ubb3c\ud559\uc801 \ub124\ud2b8\uc6cc\ud06c \ud0d0\uc0c9<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Front Pharmacol., 12(2021), \uc870\ud56d 601846,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.3389\/fphar.2021.601846\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.3389\/fphar.2021.601846<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85109788788&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref219\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Exploring%20the%20regulatory%20mechanism%20of%20HedysarumMultijugumMaxim.-Chuanxiong%20Rhizoma%20compound%20on%20HIF-VEGF%20pathway%20and%20cerebral%20ischemia-reperfusion%20injurys%20biological%20network%20based%20on%20systematic%20pharmacology&amp;publication_year=2021&amp;author=K.%20Yang&amp;author=L.%20Zeng&amp;author=A.%20Ge&amp;author=Y.%20Chen&amp;author=S.%20Wang&amp;author=X.%20Zhu&amp;author=J.%20Ge\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref219\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib221\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib221\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[221]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">G. Wang, X. Zeng, K. Yang, S. Gong, A. Ge, W. Liu, Q. He, W. Zhang, J. Ge<\/div>\n<div id=\"ref-id-sbref220\" class=\"title text-m\">Hedysarummultijugum maxim-chuanxiong rhizoma \ud654\ud569\ubb3c\uc758 \ub1cc\uacbd\uc0c9\uc5d0 \ub300\ud55c \uc2e0\uacbd\ubcf4\ud638 \ud6a8\uacfc\ub97c \uc815\ub7c9\uc801 \ub2e8\ubc31\uc9c8\uccb4\ud559\uc744 \ud1b5\ud574 \uaddc\uba85<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ubd84\uba85\ud558\ub2e4. \uae30\ubc18 \ubcf4\uc644 \ub300\uccb4. Med., 2022 (2022), \uc870\ud56d 5241902,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1155\/2022\/5241902\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1155\/2022\/5241902<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85128414552&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref220\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Uncovering%20the%20neuroprotective%20effect%20of%20hedysarummultijugum%20maxim-chuanxiong%20rhizoma%20compound%20on%20cerebral%20infarction%20through%20quantitative%20proteomics&amp;publication_year=2022&amp;author=G.%20Wang&amp;author=X.%20Zeng&amp;author=K.%20Yang&amp;author=S.%20Gong&amp;author=A.%20Ge&amp;author=W.%20Liu&amp;author=Q.%20He&amp;author=W.%20Zhang&amp;author=J.%20Ge\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref220\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib222\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib222\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[222]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">K. Yang, L. Zeng, A. Ge, Y. Shi, X. Zhu, W. Liu, J. Ge<\/div>\n<div id=\"ref-id-sbref221\" class=\"title text-m\">\ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc5d0 \ub300\ud55c hedysarummultijugummaxim.-Chuanxiong rhizoma \ud654\ud569\ubb3c\uc758 \ud6a8\uacfc: \ub124\ud2b8\uc6cc\ud06c \ubc0f \uc2e4\ud5d8\uc57d\ub9ac\ud559 \uae30\ubc18 \uc5f0\uad6c<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc0b0\ud654\ubb3c. \uba54\ub4dc. \uc138\ud3ec \uc218\uba85(Cell Longev.), 2020(2020), \uc870\ud56d 6072380,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1155\/2020\/6072380\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1155\/2020\/6072380<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85094222391&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref221\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20effect%20of%20hedysarummultijugummaxim.-Chuanxiong%20rhizoma%20compound%20on%20ischemic%20stroke%3A%20a%20research%20based%20on%20network%20and%20experimental%20pharmacology&amp;publication_year=2020&amp;author=K.%20Yang&amp;author=L.%20Zeng&amp;author=A.%20Ge&amp;author=Y.%20Shi&amp;author=X.%20Zhu&amp;author=W.%20Liu&amp;author=J.%20Ge\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref221\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib223\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib223\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[223]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">\ube44\uc544\uc624 \ud0d5<\/div>\n<div id=\"ref-id-sbref222\" class=\"title text-m\">\ub1cc\ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc5d0\uc11c mitophagy-NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4 \uacbd\ub85c\uc758 \uc5ed\ud560\uacfc \uc0bc\uce60\uc778\uc0bc \uc0ac\ud3ec\ub2cc\uacfc \uc544\uc2a4\ud2b8\ub77c\uac08\ub85c\uc0ac\uc774\ub4dc IV\uc758 \uac1c\uc785[D]<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud6c4\ub09c\ub300\ud559\uad50 \uc804\ud1b5. \ud131. \uba54\ub4dc. (2019),\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.27138\/d.cnki.ghuzc.2019.000014\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.27138\/d.cnki.ghuzc.2019.000014<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20role%20of%20mitophagy-NLRP3%20inflammasome%20pathway%20in%20cerebral%20ischemia-reperfusion%20injury%20and%20the%20intervention%20of%20Panax%20notoginseng%20saponins%20and%20astragaloside%20IVD&amp;publication_year=2019&amp;author=Biao%20Tang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref222\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib224\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib224\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[224]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">\ub098 \ub9ac<\/div>\n<div id=\"ref-id-sbref223\" class=\"title text-m\">\uc800\uc0b0\uc18c\uc131 \ud5c8\ud608\uc131 \ub1cc \uc190\uc0c1\uc744 \uac1c\uc120\ud558\uae30 \uc704\ud574 MMP-9 \ub9e4\uac1c NLRP3\/Caspase-1 \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub97c \uc870\uc808\ud558\ub294 \uc544\uc2a4\ud2b8\ub77c\uac08\ub85c\uc0ac\uc774\ub4dc IV\uc758 \ubd84\uc790 \uba54\ucee4\ub2c8\uc998[D]<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc694\ub155\ub300\ud559\uad50 \uc804\ud1b5. \ud131. \uba54\ub4dc. (2021),\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.27213\/d.cnki.glnzc.2021.000042\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.27213\/d.cnki.glnzc.2021.000042<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Molecular%20mechanism%20of%20astragaloside%20IV%20regulating%20MMP-9-mediated%20NLRP3Caspase-1%20signaling%20pathway%20to%20improve%20hypoxic-ischemic%20brain%20injuryD&amp;publication_year=2021&amp;author=Na%20Li\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref223\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib225\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib225\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[225]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">W. Xie, X. Meng, Y. Zhai, P. Zhou, T. Ye, Z. Wang, G. Sun, X. Sun<\/div>\n<div id=\"ref-id-sbref224\" class=\"title text-m\">\uc0bc\uce60\uc778\uc0bc \uc0ac\ud3ec\ub2cc\uc758 \ud56d\uc6b0\uc6b8\uc81c \ub610\ub294 \ud56d\ubd88\uc548 \ud6a8\uacfc \uae30\uc804\uc5d0 \ub300\ud55c \uac80\ud1a0\uc640 \uc2dd\ubb3c\ud654\ud559 \ubc0f \uc57d\ub9ac\ud559\uc5d0 \ub300\ud55c \ub124\ud2b8\uc6cc\ud06c \ubd84\uc11d<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ubd84\uc790, 23(4)(2018), p. 940,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.3390\/molecules23040940\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.3390\/\ubd84\uc79023040940<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85045663855&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref224\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Panax%20notoginseng%20saponins%3A%20a%20review%20of%20its%20mechanisms%20of%20antidepressant%20or%20anxiolytic%20effects%20and%20network%20analysis%20on%20phytochemistry%20and%20pharmacology&amp;publication_year=2018&amp;author=W.%20Xie&amp;author=X.%20Meng&amp;author=Y.%20Zhai&amp;author=P.%20Zhou&amp;author=T.%20Ye&amp;author=Z.%20Wang&amp;author=G.%20Sun&amp;author=X.%20Sun\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref224\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib226\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib226\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[226]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">J. Qu, N. Xu, J. Zhang, X. Geng, R. Zhang<\/div>\n<div id=\"ref-id-sbref225\" class=\"title text-m\">\uc0bc\uce60\uc778\uc0bc \uc0ac\ud3ec\ub2cc\uacfc \uc2e0\uacbd\uacc4 \uc9c8\ud658\uc5d0\uc11c\uc758 \uc751\uc6a9: \uc11c\uc0ac\uc801 \uac80\ud1a0<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc564. \ubc88\uc5ed. Med, 8(22)(2020), p. 1525,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.21037\/atm-20-6909\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.21037\/atm-20-6909<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Panax%20notoginseng%20saponins%20and%20their%20applications%20in%20nervous%20system%20disorders%3A%20a%20narrative%20review&amp;publication_year=2020&amp;author=J.%20Qu&amp;author=N.%20Xu&amp;author=J.%20Zhang&amp;author=X.%20Geng&amp;author=R.%20Zhang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref225\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib227\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib227\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[227]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">H. Liu, X. Lu, Y. Hu, X. \ud32c<\/div>\n<div id=\"ref-id-sbref226\" class=\"title text-m\">Panax ginseng\uacfc Panax notoginseng\uc758 \ud654\ud559 \uc131\ubd84\uc740 \uce58\ub8cc \ud6a8\ub2a5\uc774 \ub2e4\ub978 \uc774\uc720\ub97c \uc124\uba85\ud569\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Pharmacol. \uacb0\uc758\uc548, 161(2020), \uc870\ud56d 105263,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.phrs.2020.105263\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.phrs.2020.105263<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1043661820315711\/pdfft?md5=f06179b256e8e23dd685c57247f67d5e&amp;pid=1-s2.0-S1043661820315711-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref226\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1043661820315711\" aria-describedby=\"ref-id-sbref226\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85095773224&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref226\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Chemical%20constituents%20of%20Panax%20ginseng%20and%20Panax%20notoginseng%20explain%20why%20they%20differ%20in%20therapeutic%20efficacy&amp;publication_year=2020&amp;author=H.%20Liu&amp;author=X.%20Lu&amp;author=Y.%20Hu&amp;author=X.%20Fan\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref226\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib228\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib228\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[228]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">He Xu, Ge Jinwen, Deng Changqing, Guo Taiping, Pan Aihua, Li. \uc9c0\uc704\uc548 \ud30c\ub099\uc2a4<\/div>\n<div id=\"ref-id-sbref227\" class=\"title text-m\">\uc0bc\uce60\uc778\uc0bc \uc0ac\ud3ec\ub2cc\uc740 \uc804\ub1cc\ud5c8\ud608 \ud6c4 \ud574\ub9c8 CA1 \ubd80\uc704\uc758 \uc2e0\uacbd\uc138\ud3ec\uc0ac\uba78\uc744 \uc5b5\uc81c\ud558\ub294 \uc791\uc6a9\uacfc \uadf8 \uae30\uc804<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud131. \ubaa9\ucd08. Med., 47(08)(2016), pp. 1337-1344<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84991576432&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref227\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=notoginseng%20saponins%20inhibit%20neuronal%20apoptosis%20in%20hippocampal%20CA1%20area%20after%20global%20cerebral%20ischemia%20and%20its%20mechanism&amp;publication_year=2016&amp;author=He%20Xu&amp;author=Ge%20Jinwen&amp;author=Deng%20Changqing&amp;author=Guo%20Taiping&amp;author=Pan%20Aihua&amp;author=Li.%20Zhiyuan%20Panax\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref227\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib229\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib229\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[229]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">He Xu, Ge Jinwen, Huang Jun, Pan Aihua, Li Zhiyuan<\/div>\n<div id=\"ref-id-sbref228\" class=\"title text-m\">\uc804\ub1cc\ud5c8\ud608\uc774 \uc788\ub294 \uc131\uccb4 \uc950\uc758 \uce21\ub1cc\uc2e4 \ub1cc\uc2e4\ub9c9 \ubd80\uc704\uc758 \uc2e0\uacbd \uc7ac\uc0dd\uc5d0 \ub300\ud55c \uc0bc\uce60\uc778\uc0bc \uc0ac\ud3ec\ub2cc\uc758 \ud6a8\uacfc<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud131. \ubaa9\ucd08. Med., 47 (09) (2016), pp. 1535-1540<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85007011056&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref228\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Effects%20of%20Panax%20notoginseng%20saponins%20on%20nerve%20regeneration%20in%20the%20ependymal%20region%20of%20lateral%20ventricle%20in%20adult%20rats%20with%20global%20cerebral%20ischemia&amp;publication_year=2016&amp;author=He%20Xu&amp;author=Ge%20Jinwen&amp;author=Huang%20Jun&amp;author=Pan%20Aihua&amp;author=Li%20Zhiyuan\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref228\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib230\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib230\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[230]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">He Xu, Liu Yingfei, Wang Wei, Zhao Hong, Yan Xiaoxin, Yi Yaqiao, Ge Jinwen<\/div>\n<div id=\"ref-id-sbref229\" class=\"title text-m\">\uc804\ub1cc\ud5c8\ud608 \uc950\uc758 \ud574\ub9c8 \ub1cc\ubd80\uc885 \ubc0f GFAP \ubc1c\ud604\uc5d0 \ub300\ud55c \uc0bc\uce60\uc778\uc0bc \uc0ac\ud3ec\ub2cc\uc758 \ud6a8\uacfc<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud131. \ubaa9\ucd08. Med., 48(22)(2017), pp. 4695-4700<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Effects%20of%20Panax%20notoginseng%20saponins%20on%20hippocampal%20cerebral%20edema%20and%20GFAP%20expression%20in%20rats%20with%20global%20cerebral%20ischemia&amp;publication_year=2017&amp;author=He%20Xu&amp;author=Liu%20Yingfei&amp;author=Wang%20Wei&amp;author=Zhao%20Hong&amp;author=Yan%20Xiaoxin&amp;author=Yi%20Yaqiao&amp;author=Ge%20Jinwen\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref229\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib231\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib231\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[231]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">He Xu, Liu Yingfei, Wang Wei, Sun Qiumin, Pan Aihua, Ge Jinwen<\/div>\n<div id=\"ref-id-sbref230\" class=\"title text-m\">\uc804\ub1cc\ud5c8\ud608 \uc950\uc758 \ud559\uc2b5 \ubc0f \uae30\uc5b5\uc5d0 \ub300\ud55c \uc0bc\uce60\uc778\uc0bc \uc0ac\ud3ec\ub2cc\uc758 \ud6a8\uacfc \ubc0f \uc791\uc6a9\uae30\uc804<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud131. \ubaa9\ucd08. Med., 50(22)(2019), pp. 5521-5526<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/doi.org\/10.3390\/su11195521\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref230\"><span class=\"anchor-text\">CrossRef<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85073589086&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref230\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Effects%20of%20Panax%20notoginseng%20saponins%20on%20learning%20and%20memory%20in%20rats%20with%20global%20cerebral%20ischemia%20and%20its%20mechanism%20of%20action&amp;publication_year=2019&amp;author=He%20Xu&amp;author=Liu%20Yingfei&amp;author=Wang%20Wei&amp;author=Sun%20Qiumin&amp;author=Pan%20Aihua&amp;author=Ge%20Jinwen\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref230\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib232\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib232\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[232]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">\ud0d5\ubc4c\uc624<\/div>\n<div id=\"ref-id-sbref231\" class=\"title text-m\">\ub1cc\ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc5d0\uc11c mitophagy-NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4 \uacbd\ub85c\uc758 \uc5ed\ud560\uacfc \uc0bc\uce60\uc778\uc0bc \uc0ac\ud3ec\ub2cc\uacfc \uc544\uc2a4\ud2b8\ub77c\uac08\ub85c\uc0ac\uc774\ub4dc IV\uc758 \uac1c\uc785[D]<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud6c4\ub09c\ub300\ud559\uad50 \uc804\ud1b5. \ud131. \uba54\ub4dc. (2019),\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.27138\/d.cnki.ghuzc.2019.000014\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.27138\/d.cnki.ghuzc.2019.000014<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20role%20of%20mitophagy-NLRP3%20inflammasome%20pathway%20in%20cerebral%20ischemia-reperfusion%20injury%20and%20the%20intervention%20of%20Panax%20notoginseng%20saponins%20and%20astragaloside%20IVD&amp;publication_year=2019&amp;author=Tang%20Biao\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref231\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib233\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib233\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[233]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">\uc800\uc6b0\uc789<\/div>\n<div id=\"ref-id-sbref232\" class=\"title text-m\">DRP1\/NLRP3 \uacbd\ub85c\ub97c \uae30\ubc18\uc73c\ub85c \ud55c \uae09\uc131 \ub1cc\uacbd\uc0c9 \ud6c4 \ubc1c\uc5f4\uc99d\uc5d0 \ub300\ud55c \ub3c4\ud64d\uc2dc\uc6b0 \ub2ec\uc784\uc758 \ud6a8\uacfc \ubc0f \uae30\uc804[D]<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ubca0\uc774\uc9d5\ub300\ud559\uad50 \uc804\ud1b5. \ud131. \uba54\ub4dc. (2021),\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.26973\/d.cnki.gbjzu.2021.000498\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.26973\/d.cnki.gbjzu.2021.000498<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20effect%20and%20mechanism%20of%20Taohong%20Siwu%20decoction%20on%20pyroptosis%20after%20acute%20cerebral%20infarction%20based%20on%20DRP1NLRP3%20pathwayD&amp;publication_year=2021&amp;author=Zhou%20Ying\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref232\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib234\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib234\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[234]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">\uc655 \uba4d\uba4d<\/div>\n<div id=\"ref-id-sbref233\" class=\"title text-m\">\ub1cc\ud5c8\ud608-\uc7ac\uad00\ub958 \uc950\uc758 \uc138\ud3ec \ubc1c\uc5f4\uc5d0 \ub300\ud55c \ub3c4\ud64d\uc2dc\uc6b0 \ub2ec\uc784\uc758 \uc870\uc808 \ud6a8\uacfc\uc5d0 \uad00\ud55c \uc5f0\uad6c [D]<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc548\ud718\ub300\ud559\uad50 \uc804\ud1b5. \ud131. \uba54\ub4dc. (2020),\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.26922\/d.cnki.ganzc.2020.000120\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.26922\/d.cnki.ganzc.2020.000120<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Study%20on%20the%20regulatory%20effect%20of%20Taohong%20Siwu%20decoction%20on%20cell%20pyroptosis%20in%20rats%20with%20cerebral%20ischemia-reperfusion%20D&amp;publication_year=2020&amp;author=Wang%20Mengmeng\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref233\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib235\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib235\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[235]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">\ub9c8\uc789\uc950\uc548, \uc0f9\uc720\uc789, \uc655\ub354\uc9c0\uc5d0,\u00a0<em>\uc678.<\/em><\/div>\n<div id=\"ref-id-sbref234\" class=\"title text-m\">\uac10\uc78e \ud50c\ub77c\ubcf4\ub178\uc774\ub4dc\uc758 \ud56d\uc5fc\uc99d \ubc0f \ud56d\uc0b0\ud654 \uc2e0\uacbd\ubcf4\ud638 \ud6a8\uacfc\u00a0<span class=\"small-caps\">\ub514<\/span>-\uac08\ub77d\ud1a0\uc624\uc2a4\ub85c \uc778\ud574 \ub178\ud654\ub41c \uc950<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud478\ub2e8 J.: Med. Ed., 42(1)(2015), pp. 7-12<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Anti-inflammatory%20and%20antioxidant%20neuroprotective%20effects%20of%20persimmon%20leaf%20flavonoids%20on%20D-galactose-induced%20aging%20mice&amp;publication_year=2015&amp;author=Ma%20Yingjuan&amp;author=Shang%20Yuying&amp;author=Wang%20Dejie\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref234\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib236\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib236\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[236]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">\uc9c4\ud398\uc774\uc7a5<\/div>\n<div id=\"ref-id-sbref235\" class=\"title text-m\">L-NAME \uc720\ubc1c \uace0\ud608\uc555 \uc950\uc5d0 \ub300\ud55c \uac10\uc78e\uc758 \ucd1d \ud50c\ub77c\ubcf4\ub178\uc774\ub4dc\uc758 \ud56d\uace0\ud608\uc555 \ud6a8\uacfc \ubc0f \uae30\uc804 [D]<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ub09c\ub2dd \uad11\uc2dc \uc758\uacfc\ub300\ud559(2008)<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20antihypertensive%20effect%20and%20mechanism%20of%20total%20flavonoids%20from%20persimmon%20leaves%20on%20L-NAME-induced%20hypertensive%20rats%20D&amp;publication_year=2008&amp;author=Qin%20Feizhang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref235\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib237\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib237\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[237]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">\ud0d5 \uc9d5<\/div>\n<div id=\"ref-id-sbref236\" class=\"title text-m\">\uc2ec\ud608\uad00 \uc9c8\ud658 \ubc0f \ub2f9\ub1e8\ubcd1 \uc608\ubc29 \ubc0f \uce58\ub8cc\uc5d0 \uc788\uc5b4\uc11c Ye\uc640 \uadf8 \uc81c\ud488\uc758 \uc0c8\ub85c\uc6b4 \uc9c4\uc804<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc0b0\uc2dc\uba54\ub4dc. J., 37(16)(2008), pp. 740-741<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20new%20progress%20of%20Ye%20and%20its%20products%20in%20the%20prevention%20and%20treatment%20of%20cardiovascular%20disease%20and%20diabetes&amp;publication_year=2008&amp;author=Tang%20Jing\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref236\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib238\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib238\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[238]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">\ubca0\uc774\uc6e8\uc774\uc820<\/div>\n<div id=\"ref-id-sbref237\" class=\"title text-m\">\ub1cc\ud5c8\ud608\uc5d0 \ub300\ud55c \uac10\uc78e \uc720\ud6a8\uc131\ubd84\uacfc \ub098\uc624\uc2e0\uce6d\uc815\uc758 \uc2e0\uacbd\ubcf4\ud638 \ud6a8\uacfc\uc5d0 \uad00\ud55c \uc5f0\uad6c[D]<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uad11\uc800\uc6b0 \uc468\uc6d0\ub300\ud559\uad50(2004)<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Study%20on%20the%20neuroprotective%20effect%20of%20persimmon%20leaf%20active%20ingredients%20and%20Naoxinqing%20tablet%20on%20cerebral%20ischemia%20D&amp;publication_year=2004&amp;author=Bei%20Weijian\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref237\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib239\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib239\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[239]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">\ubbfc\ub3d9\uc704, \ub9ac\ud6d9\uc60c, \uad00\ub808, \uc7a5\uc7a5, \uc7a5\ud558\uc774\ub2dd, \ucd94\uc774\uc2e0\uc704\uc5d0, \uc655\ud391, \uc870\uc6a9\uac15<\/div>\n<div id=\"ref-id-sbref238\" class=\"title text-m\">\ub1cc\ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1 \ubaa8\ub378 \uc950\uc5d0 \ub300\ud55c Naoxinqing\uc758 \ubcf4\ud638 \uba54\ucee4\ub2c8\uc998<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud131. \uc870\uc9c1\uacf5\ud559 \uacb0\uc758\uc548, 24(02)(2020), pp. 215-222<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20protective%20mechanism%20of%20Naoxinqing%20on%20cerebral%20ischemia-reperfusion%20injury%20model%20rats&amp;publication_year=2020&amp;author=Min%20Dongyu&amp;author=Li%20Hongyan&amp;author=Guan%20Le&amp;author=Chang%20Jiang&amp;author=Zhang%20Haining&amp;author=Cui%20Xinyue&amp;author=Wang%20Peng&amp;author=Cao%20Yonggang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref238\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib240\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib240\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[240]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">XD Wen, EH Liu, J. Yang, CY Li, W. Gao, LW Qi, CZ Wang, CS Yuan, P. Li<\/div>\n<div id=\"ref-id-sbref239\" class=\"title text-m\">\uc561\uccb4 \ud06c\ub85c\ub9c8\ud1a0\uadf8\ub798\ud53c-4\uc911\uadf9\uc790 \ube44\ud589\uc2dc\uac04 \uc9c8\ub7c9\ubd84\uc11d\ubc95\uc744 \uc774\uc6a9\ud55c \uc950 \uc18c\ubcc0 \ub0b4 \ubd80\uc591\ud658\uc624\ud0d5 \ub300\uc0ac\uc0b0\ubb3c\uc758 \ub3d9\uc815<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J.Pharm. \ubc14\uc774\uc624\uba54\ub4dc. Anal., 67\u201368 (2012), pp. 114-122,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.jpba.2012.04.026\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.jpba.2012.04.026<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0731708512002233\/pdfft?md5=9c0b4b4026978758737165abec6fb657&amp;pid=1-s2.0-S0731708512002233-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref239\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0731708512002233\" aria-describedby=\"ref-id-sbref239\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84862142316&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref239\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Identification%20of%20metabolites%20of%20Buyang%20Huanwu%20decoction%20in%20rat%20urine%20using%20liquid%20chromatography-quadrupole%20time-of-flight%20mass%20spectrometry&amp;publication_year=2012&amp;author=X.D.%20Wen&amp;author=E.H.%20Liu&amp;author=J.%20Yang&amp;author=C.Y.%20Li&amp;author=W.%20Gao&amp;author=L.W.%20Qi&amp;author=C.Z.%20Wang&amp;author=C.S.%20Yuan&amp;author=P.%20Li\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref239\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib241\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib241\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[241]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">H. Zhang, WR Wang, R. Lin, JY Zhang, QL Ji, QQ Lin, LN Yang<\/div>\n<div id=\"ref-id-sbref240\" class=\"title text-m\">\ubd80\uc591\ud658\uc624\ud0d5\uc740 \uc950\uc758 CRP\uc640 CD40\uc744 \uac10\uc18c\uc2dc\ucf1c \uae30\uacb0\ud54d \ubc0f \ud608\uc561 \uc815\uccb4 \uc99d\ud6c4\uad70\uc744 \ub3d9\ubc18\ud55c \uad00\uc0c1 \ub3d9\ub9e5 \uc2ec\uc7a5 \uc9c8\ud658\uc744 \uac1c\uc120\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. Ethnopharmacol., 130 (1) (2010), pp. 98-102,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.jep.2010.04.017\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.jep.2010.04.017<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0378874110002485\/pdfft?md5=a149cf59db6c2f5f3eaba545e992b69a&amp;pid=1-s2.0-S0378874110002485-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref240\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0378874110002485\" aria-describedby=\"ref-id-sbref240\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-77953808121&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref240\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Buyang%20Huanwu%20decoction%20ameliorates%20coronary%20heart%20disease%20with%20Qi%20deficiency%20and%20blood%20stasis%20syndrome%20by%20reducing%20CRP%20and%20CD40%20in%20rats&amp;publication_year=2010&amp;author=H.%20Zhang&amp;author=W.R.%20Wang&amp;author=R.%20Lin&amp;author=J.Y.%20Zhang&amp;author=Q.L.%20Ji&amp;author=Q.Q.%20Lin&amp;author=L.N.%20Yang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref240\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib242\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib242\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[242]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">K. Yang, L. Zeng, A. Ge, Y. Shi, X. Zhu, W. Liu, J. Ge<\/div>\n<div id=\"ref-id-sbref241\" class=\"title text-m\">\ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc5d0 \ub300\ud55c hedysarum multijugum maxim.-Chuanxiong rhizoma \ud654\ud569\ubb3c\uc758 \ud6a8\uacfc: \ub124\ud2b8\uc6cc\ud06c \ubc0f \uc2e4\ud5d8 \uc57d\ub9ac\ud559 \uae30\ubc18 \uc5f0\uad6c<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc0b0\ud654\ubb3c. \uba54\ub4dc. \uc138\ud3ec \uc218\uba85(Cell Longev.), 2020(2020), \uc870\ud56d 6072380,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1155\/2020\/6072380\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1155\/2020\/6072380<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85094222391&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref241\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20effect%20of%20hedysarum%20multijugum%20maxim.-Chuanxiong%20rhizoma%20compound%20on%20ischemic%20stroke%3A%20a%20research%20based%20on%20network%20and%20experimental%20pharmacology&amp;publication_year=2020&amp;author=K.%20Yang&amp;author=L.%20Zeng&amp;author=A.%20Ge&amp;author=Y.%20Shi&amp;author=X.%20Zhu&amp;author=W.%20Liu&amp;author=J.%20Ge\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref241\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib243\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib243\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[243]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">K. Yang, L. Zeng, A. Ge, Y. Chen, S. Wang, X. Zhu, J. Ge<\/div>\n<div id=\"ref-id-sbref242\" class=\"title text-m\">HIF-VEGF \uacbd\ub85c\uc5d0 \ub300\ud55c hedysarum multijugum maxim.-chuanxiong rhizoma \ud654\ud569\ubb3c\uc758 \uc870\uc808 \uba54\ucee4\ub2c8\uc998\uacfc \uccb4\uacc4\uc801 \uc57d\ub9ac\ud559\uc744 \uae30\ubc18\uc73c\ub85c \ud55c \ub1cc\ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1\uc758 \uc0dd\ubb3c\ud559\uc801 \ub124\ud2b8\uc6cc\ud06c \ud0d0\uc0c9<\/div>\n<\/div>\n<div class=\"host u-font-sans\">Front Pharm., 12 (2021), \uc870\ud56d 601846,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.3389\/fphar.2021.601846\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.3389\/fphar.2021.601846<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85109788788&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref242\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Exploring%20the%20regulatory%20mechanism%20of%20hedysarum%20multijugum%20maxim.-chuanxiong%20rhizoma%20compound%20on%20HIF-VEGF%20pathway%20and%20cerebral%20ischemia-reperfusion%20injurys%20biological%20network%20based%20on%20systematic%20pharmacology&amp;publication_year=2021&amp;author=K.%20Yang&amp;author=L.%20Zeng&amp;author=A.%20Ge&amp;author=Y.%20Chen&amp;author=S.%20Wang&amp;author=X.%20Zhu&amp;author=J.%20Ge\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref242\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib244\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib244\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[244]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Y. She, L. Shao, Y. Zhang, Y. Hao, Y. Cai, Z. Cheng, C. Deng, X. Liu<\/div>\n<div id=\"ref-id-sbref243\" class=\"title text-m\">\uc950\uc758 \ub1cc\ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1 \ud6c4 \ubc1c\uc5f4\uc99d\uc5d0 \ub300\ud55c \ubd80\uc591\ud658\uc624\ud0d5\uc758 \ubc30\ub2f9\uccb4\uc758 \uc2e0\uacbd\ubcf4\ud638 \ud6a8\uacfc<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. Ethnopharmacol., 242(2019), \uc870\ud56d 112051,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1016\/j.jep.2019.112051\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1016\/j.jep.2019.112051<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor pdf link anchor-default anchor-icon-left\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0378874119306816\/pdfft?md5=20e0d49e6cd3b78abd9bc6de80190401&amp;pid=1-s2.0-S0378874119306816-main.pdf\" target=\"_blank\" rel=\"nofollow noopener\" aria-describedby=\"ref-id-sbref243\"><span class=\"anchor-text\">PDF \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0378874119306816\" aria-describedby=\"ref-id-sbref243\"><span class=\"anchor-text\">\uae30\uc0ac \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85068926621&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref243\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Neuroprotective%20effect%20of%20glycosides%20in%20BuyangHuanwu%20Decoction%20on%20pyroptosis%20following%20cerebral%20ischemia-reperfusion%20injury%20in%20rats&amp;publication_year=2019&amp;author=Y.%20She&amp;author=L.%20Shao&amp;author=Y.%20Zhang&amp;author=Y.%20Hao&amp;author=Y.%20Cai&amp;author=Z.%20Cheng&amp;author=C.%20Deng&amp;author=X.%20Liu\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref243\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib245\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib245\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[245]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">\ud310\uc900\uc774, \ucc9c\uc6a9\ube48, \ub958\uce58\ud654, \ub904\uc60c\ud551, \ub9ac\ub09c\ud321, \ud669\uc174\uc6d0<\/div>\n<div id=\"ref-id-sbref244\" class=\"title text-m\">\uc950\uc758 \ub1cc\ud5c8\ud608-\uc7ac\uad00\ub958 \uc190\uc0c1 \ud6c4 \ub871\uc9c0 \ub2ec\uc784\uc774 Caspase-1 \ubc0f IL-18 \ub2e8\ubc31\uc9c8 \ubc1c\ud604\uc5d0 \ubbf8\uce58\ub294 \uc601\ud5a5<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. \ud6c4\ub09c \ub300\ud559\uad50 \uc804\ud1b5. \ud131. Med., 41 (04) (2021), pp. 518-522<\/div>\n<div class=\"ReferenceLinks u-font-sans\"><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Effects%20of%20Longzhi%20Decoction%20on%20Caspase-1%20and%20IL-18%20protein%20expression%20after%20cerebral%20ischemia-reperfusion%20injury%20in%20rats&amp;publication_year=2021&amp;author=Fan%20Junyi&amp;author=Chen%20Yongbin&amp;author=Liu%20Qihua&amp;author=Luo%20Yanping&amp;author=Li%20Nanfang&amp;author=Huang%20Xianwen\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref244\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib246\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib246\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[246]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">\ub8e8\uc0e4\uc624\uce6d, \uc7a5\uccb8, \uc468\uc774<\/div>\n<div id=\"ref-id-sbref245\" class=\"title text-m\">\ud5c8\ud608\uc131 \ub1cc\uc878\uc911 \ud68c\ubcf5\uae30 \ud658\uc790\uc5d0 \ub300\ud55c Yiqi Huoxue Tonluo \ub2ec\uc784\uc758 \ud6a8\uacfc\uc640 \ud608\uc5ed\ud559 \uc218\uc900, NO, VEGF \ubc0f ET-1 \uc218\uc900\uc5d0 \ubbf8\uce58\ub294 \uc601\ud5a5<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc4f0\ucd28 \uc804\ud1b5. \ud131. Med., 37(02)(2019), pp. 142-144<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85142872209&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref245\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Effect%20of%20Yiqi%20Huoxue%20Tongluo%20Decoction%20on%20Ischemic%20Stroke%20Convalescent%20Patients%20and%20Its%20Effects%20on%20Hemodynamic%20Levels%2C%20NO%2C%20VEGF%20and%20ET-1%20Levels&amp;publication_year=2019&amp;author=Lu%20Xiaoqing&amp;author=Zhang%20Qian&amp;author=Sun%20Yi\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref245\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib247\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib247\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[247]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">Jiang Limin, Liu Xiangzhe, Sang Feng, Guo Xiangdong, Ji Peng<\/div>\n<div id=\"ref-id-sbref246\" class=\"title text-m\">\uae30\ub97c \uc790\uc591\ud558\uace0 \ud608\uc561\uc744 \ud65c\uc131\ud654\uc2dc\ud0a4\ub294 \ubc29\ubc95\uc740 \ubc1c\uc5f4\uc99d\uc744 \uc5b5\uc81c\ud558\uc5ec \uae09\uc131 \ud5c8\ud608\uc131 \ub1cc\uc878\uc911 \uc950\uc758 \ub1cc \uc870\uc9c1 \uc5fc\uc99d\uc744 \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. \uad11\uc800\uc6b0 \ub300\ud559\uad50 \uc804\ud1b5. \ud131. Med., 39 (01) (2022), pp. 152-158,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.13359\/j.cnki.gzxbtcm.2022.01.026\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.13359\/j.cnki.gzxbtcm.2022.01.026<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20method%20of%20nourishing%20qi%20and%20activating%20blood%20reduces%20brain%20tissue%20inflammation%20in%20rats%20with%20acute%20ischemic%20stroke%20by%20inhibiting%20pyroptosis&amp;publication_year=2022&amp;author=Jiang%20Limin&amp;author=Liu%20Xiangzhe&amp;author=Sang%20Feng&amp;author=Guo%20Xiangdong&amp;author=Ji%20Peng\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref246\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib248\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib248\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[248]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">\uc591\ud718, \ud0d5\uc2a4\ucd94, \uc0e4\uc624\ud321\ub9c1<\/div>\n<div id=\"ref-id-sbref247\" class=\"title text-m\">\ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc5d0 \ub300\ud55c \uc2e0\ub098\uc624\ubcf5\uc6d0\ud0d5\uacfc \uc2f1\ub098\uc624\uac1c\uad50\uce68\uc758 \uc784\uc0c1\uad00\ucc30<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc6d4\ub4dc J. \uc778\ud14c\uadf8\ub974. Med., 15 (01) (2020), pp. 160-164+169,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.13935\/j.cnki.sjzx.200135\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.13935\/j.cnki.sjzx.200135<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Clinical%20observation%20of%20Shennao%20Fuyuan%20decoction%20combined%20with%20Xingnao%20Kaiqiao%20acupuncture%20for%20ischemic%20stroke&amp;publication_year=2020&amp;author=Yang%20Hui&amp;author=Tang%20Shiqiu&amp;author=Shao%20Fangling\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref247\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib249\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib249\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[249]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">\uc655\uc720\uc789<\/div>\n<div id=\"ref-id-sbref248\" class=\"title text-m\">MCAO \uc950\uc758 Nogo-A \ubc0f GAP-43 \ubc1c\ud604\uc5d0 \ub300\ud55c hUC-MSC\uc640 \uacb0\ud569\ub41c \uc2e0\ub098\uc624 \ubcf5\uc6d0 \ub2ec\uc784\uc758 \ud6a8\uacfc[D]<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud6c4\ub09c\ub300\ud559\uad50 \uc804\ud1b5. \ud131. \uba54\ub4dc. (2021),\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.27138\/d.cnki.ghuzc.2021.000154\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.27138\/d.cnki.ghuzc.2021.000154<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Effects%20of%20Shennao%20Fuyuan%20Decoction%20combined%20with%20hUC-MSCs%20on%20the%20expression%20of%20Nogo-A%20and%20GAP-43%20in%20MCAO%20ratsD&amp;publication_year=2021&amp;author=Wang%20Yuying\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref248\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib250\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib250\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[250]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">\ub9ac \uc2e0<\/div>\n<div id=\"ref-id-sbref249\" class=\"title text-m\">\uc138\ud3ec \ubc1c\uc5f4 \uba54\ucee4\ub2c8\uc998\uc744 \uae30\ubc18\uc73c\ub85c \ud3ec\ub3c4\ub2f9\uacfc \uc0b0\uc18c\uac00 \uacb0\ud54d\ub41c PC12 \uc138\ud3ec\uc5d0 \ub300\ud55c \uc2e0\ub098\uc624 \ubcf5\uc6d0 \ub2ec\uc784\uc758 \ubcf4\ud638 \ud6a8\uacfc\uc5d0 \uad00\ud55c \uc5f0\uad6c [D]<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ud6c4\ub09c\ub300\ud559\uad50 \uc804\ud1b5. \ud131. \uba54\ub4dc. (2019),\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.27138\/d.cnki.ghuzc.2019.000152\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.27138\/d.cnki.ghuzc.2019.000152<\/span><\/a><\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Study%20on%20the%20protective%20effect%20of%20Shennao%20Fuyuan%20decoction%20on%20PC12%20cells%20deficient%20in%20glucose%20and%20oxygen%20based%20on%20the%20mechanism%20of%20cell%20pyroptosis%20D&amp;publication_year=2019&amp;author=Xin%20Li\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref249\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib251\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib251\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[251]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">R. \uc591, X. \uc7a5<\/div>\n<div id=\"ref-id-sbref250\" class=\"title text-m\">\ud328\ud608\uc99d\uc73c\ub85c \uc778\ud55c \ud3d0 \uc190\uc0c1\uc758 \ud5e4\ud30c\ub9b0 \uce58\ub8cc\ub97c \uc704\ud55c \uc7a0\uc7ac\uc801\uc778 \uc0c8\ub85c\uc6b4 \uacbd\ub85c: hMGB1-LPS\ub85c \uc720\ubc1c\ub41c \uce74\uc2a4\ud30c\uc81c-11 \ud65c\uc131\ud654\ub97c \ucc28\ub2e8\ud558\uc5ec \ud3d0 \ub0b4\ud53c \uc138\ud3ec \uc5f4\ubd84\ud574\uc99d\uc744 \uc5b5\uc81c\ud569\ub2c8\ub2e4.<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc804\uba74 \uc138\ud3ec \uac10\uc5fc. Microbiol., 12(2022), \uc870\ud56d 984835,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.3389\/fcimb.2022.984835\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.3389\/fcimb.2022.984835<\/span><\/a><\/div>\n<div class=\"comment\">PMID: 36189354; PMCID: PMC9519888.<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85139032884&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref250\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=A%20potential%20new%20pathway%20for%20heparin%20treatment%20of%20sepsis-induced%20lung%20injury%3A%20inhibition%20of%20pulmonary%20endothelial%20cell%20pyroptosis%20by%20blocking%20hMGB1-LPS-induced%20caspase-11%20activation&amp;publication_year=2022&amp;author=R.%20Yang&amp;author=X.%20Zhang\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref250\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib252\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib252\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[252]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">A. \ud504\ub77c\ud0c0\ud310, T. \ub77c\uc790\ubaa8\ud55c<\/div>\n<div id=\"ref-id-sbref251\" class=\"title text-m\">\uc2e4\ud5d8\uc801 \uc2ec\uadfc\uacbd\uc0c9\uc5d0\uc11c \ubd80\ub4dc\ub7ec\uc6b4 \ucf54\ucf54\ub11b \ubb3c\uc758 \ud56d\uc0b0\ud654 \ubc0f \ud56d\ud608\uc804 \ud65c\uc131<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. Food Biochem., 35(5)(2011), pp. 1501-1507<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/doi.org\/10.1111\/j.1745-4514.2010.00471.x\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref251\"><span class=\"anchor-text\">CrossRef<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-80053532261&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref251\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Antioxidant%20and%20antithrombotic%20activity%20of%20tender%20coconut%20water%20in%20experimental%20myocardial%20infarction&amp;publication_year=2011&amp;author=A.%20Prathapan&amp;author=T.%20Rajamohan\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref251\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib253\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib253\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[253]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">N. Radenahmad, F. Saleh, K. Sawangjaroen, U. Vongvatcharanon, P. Subhadhirasakul, W. Rundorn, B. Withyachumnarnkul, JR Connor<\/div>\n<div id=\"ref-id-sbref252\" class=\"title text-m\">\uc54c\uce20\ud558\uc774\uba38\ubcd1\uacfc \uad00\ub828\ub41c \uc77c\ubd80 \ubcd1\ub9ac \ud604\uc0c1\uc744 \ud06c\uac8c \uc904\uc77c \uc218 \uc788\ub294 \uc7a0\uc7ac\uc801 \uce58\ub8cc\uc81c\uc778 \uc5b4\ub9b0 \ucf54\ucf54\ub11b \uc8fc\uc2a4: \uc0c8\ub85c\uc6b4 \ubc1c\uacac<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ube0c\ub974. J. Nutr., 105(5)(2011), pp. 738-746,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1017\/S0007114510004241\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1017\/S0007114510004241<\/span><\/a><\/div>\n<div class=\"comment\">Epub 2010\ub144 11\uc6d4 30\uc77c. PMID: 21114897<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-79953137074&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref252\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Young%20coconut%20juice%2C%20a%20potential%20therapeutic%20agent%20that%20could%20significantly%20reduce%20some%20pathologies%20associated%20with%20Alzheimers%20disease%3A%20novel%20findings&amp;publication_year=2011&amp;author=N.%20Radenahmad&amp;author=F.%20Saleh&amp;author=K.%20Sawangjaroen&amp;author=U.%20Vongvatcharanon&amp;author=P.%20Subhadhirasakul&amp;author=W.%20Rundorn&amp;author=B.%20Withyachumnarnkul&amp;author=J.R.%20Connor\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref252\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib254\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib254\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[254]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">RH \ubd48\uac70<\/div>\n<div id=\"ref-id-sbref253\" class=\"title text-m\">\uc57d\ub825\ud559\u00a0<span class=\"small-caps\">\uc5d8<\/span>-\uc544\ub974\uae30\ub2cc<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\ubc14\uafb8\ub2e4. \uac70\uae30. Health Med, 20(3)(2014), pp. 48-54<\/div>\n<div class=\"comment\">PMID: 24755570<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-84904062805&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref253\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=The%20pharmacodynamics%20of%20L-arginine&amp;publication_year=2014&amp;author=R.H.%20B%C3%B6ger\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref253\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib255\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib255\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[255]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">D. Cylwik, A. Mogielnicki, W. Buczko<\/div>\n<div id=\"ref-id-sbref254\" class=\"title text-m\"><span class=\"small-caps\">\uc5d8<\/span>-\uc544\ub974\uae30\ub2cc\uacfc \uc2ec\ud608\uad00\uacc4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc81c\uc57d \uad6d\ud68c\uc758\uc6d0, 57(1)(2005), pp. 14-22<\/div>\n<div class=\"comment\">PMID: 15849373<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-18044377751&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref254\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=L-arginine%20and%20cardiovascular%20system&amp;publication_year=2005&amp;author=D.%20Cylwik&amp;author=A.%20Mogielnicki&amp;author=W.%20Buczko\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref254\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib256\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib256\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[256]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">D. Cylwik, A. Mogielnicki, K. Kramkowski, J. Stokowski, W. Buczko<\/div>\n<div id=\"ref-id-sbref255\" class=\"title text-m\">\ud56d\ud608\uc804 \ud6a8\uacfc\u00a0<span class=\"small-caps\">\uc5d8<\/span>- \uace0\ud608\uc555 \uc950\uc758 \uc544\ub974\uae30\ub2cc<\/div>\n<\/div>\n<div class=\"host u-font-sans\">J. Physiol. Pharm., 55(3)(2004), pp. 563-574<\/div>\n<div class=\"comment\">PMID: 15381827<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-4844228829&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref255\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Antithrombotic%20effect%20of%20L-arginine%20in%20hypertensive%20rats&amp;publication_year=2004&amp;author=D.%20Cylwik&amp;author=A.%20Mogielnicki&amp;author=K.%20Kramkowski&amp;author=J.%20Stokowski&amp;author=W.%20Buczko\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref255\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<li><span class=\"label u-font-sans\"><a id=\"ref-id-bib257\" class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889#bbib257\" data-aa-button=\"sd:product:journal:article:location=references:type=anchor:name=citation-name\"><span class=\"anchor-text\">[257]<\/span><\/a><\/span>\n<div class=\"contribution\">\n<div class=\"authors u-font-sans\">SA \ud0c0\ub204\uc138\ud478\ud14c\ub85c, MT Lin, SL \uc608, CL \uc608<\/div>\n<div id=\"ref-id-sbref256\" class=\"title text-m\">\uc815\ub9e5 \ub0b4 \uc544\ub974\uae30\ub2cc \ud22c\uc5ec\ub294 NLRP3 \uc5fc\uc99d\ubcf5\ud569\uccb4 \ud65c\uc131\uc744 \ud558\ud5a5 \uc870\uc808\ud558\uace0 \ubcf5\ud569\uc131 \ud328\ud608\uc99d\uc774 \uc788\ub294 \uc0dd\uc950\uc758 \uae09\uc131 \uc2e0\uc7a5 \uc190\uc0c1\uc744 \uc57d\ud654\uc2dc\ud0b5\ub2c8\ub2e4<\/div>\n<\/div>\n<div class=\"host u-font-sans\">\uc911\uc7ac. Inflamm., 2020(2020), \uc870\ud56d 3201635,\u00a0<a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1155\/2020\/3201635\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"anchor-text\">10.1155\/2020\/3201635<\/span><\/a><\/div>\n<div class=\"comment\">PMID: 32454788; PMCID:PMC7238342.<\/div>\n<div class=\"ReferenceLinks u-font-sans\">\n<div class=\"link u-margin-m-right u-display-inline\"><a class=\"es-link found-doi icon-small\" target=\"_blank\" rel=\"noopener\"><span class=\"text\">\uae30\uc0ac \ubcf4\uae30<\/span>\u00a0<\/a><\/div>\n<p><a class=\"anchor link anchor-default\" href=\"https:\/\/www.scopus.com\/inward\/record.url?eid=2-s2.0-85085510204&amp;partnerID=10&amp;rel=R3.0.0\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref256\"><span class=\"anchor-text\">Scopus\uc5d0\uc11c \ubcf4\uae30<\/span><\/a><a class=\"anchor link anchor-default\" href=\"https:\/\/scholar.google.com\/scholar_lookup?title=Intravenous%20Arginine%20Administration%20Downregulates%20NLRP3%20inflammasome%20activity%20and%20attenuates%20acute%20kidney%20injury%20in%20mice%20with%20polymicrobial%20sepsis&amp;publication_year=2020&amp;author=S.A.%20Tanuseputero&amp;author=M.T.%20Lin&amp;author=S.L.%20Yeh&amp;author=C.L.%20Yeh\" target=\"_blank\" rel=\"noopener noreferrer\" aria-describedby=\"ref-id-sbref256\"><span class=\"anchor-text\">\uad6c\uae00 \ud559\uc220\uac80\uc0c9<\/span><\/a><\/p>\n<\/div>\n<\/li>\n<\/ol>\n<\/section>\n<\/section>\n<div id=\"section-cited-by\">\n<section class=\"ListArticles preview\" aria-label=\"\uc778\uc6a9\uc790\">\n<div class=\"PageDivider\"><\/div>\n<header id=\"citing-articles-header\">\n<h2 class=\"u-h4 u-margin-l-ver u-font-serif\">\uc778\uc6a9(7)<\/h2>\n<\/header>\n<div aria-describedby=\"citing-articles-header\">\n<div class=\"citing-articles u-margin-l-bottom\">\n<ul>\n<li class=\"ListArticleItem u-margin-l-bottom\">\n<div class=\"sub-heading u-margin-xs-bottom\">\n<p id=\"citing-articles-article-0-title\" class=\"u-font-serif\"><a class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0378874123009492\"><span class=\"anchor-text\">Bombyx batryticatus \ucd94\ucd9c\ubb3c\uc740 \uc751\uace0 \uc778\uc790 \u216b\uc744 \ud65c\uc131\ud654\ud558\uc5ec \ub1cc \ud5c8\ud608\/\uc7ac\uad00\ub958 \uc190\uc0c1\uc774 \uc788\ub294 \uc950\uc758 \ud608\uad00 \uc2e0\uc0dd\uc744 \ucd09\uc9c4\ud569\ub2c8\ub2e4.<\/span><\/a><\/p>\n<div class=\"text-s\">2024\ub144 \ubbfc\uc871\uc57d\ub9ac\ud559\ud68c\uc9c0<\/div>\n<\/div>\n<div class=\"buttons text-s\">\n<p>&nbsp;<\/p>\n<\/div>\n<\/li>\n<li class=\"ListArticleItem u-margin-l-bottom\">\n<div class=\"sub-heading u-margin-xs-bottom\">\n<p id=\"citing-articles-article-1-title\" class=\"u-font-serif\"><a class=\"anchor anchor-default\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0378874123008589\"><span class=\"anchor-text\">\ub1cc \ud5c8\ud608 \ubc0f \uc7ac\uad00\ub958 \ud6c4 \uc18c\uad50\uc138\ud3ec \ud53c\ub85c\uc99d\uc5d0 \ub300\ud55c \uac78\ub450\ud654\ud559 \ub2ec\uc784\uc758 \uc2e0\uacbd\ubcf4\ud638 \ud6a8\uacfc - \uad50\ud608\uad00 \ub2e8\uc704\uc758 \uad00\uc810\uc5d0\uc11c<\/span><\/a><\/p>\n<div class=\"text-s\">2024\ub144 \ubbfc\uc871\uc57d\ub9ac\ud559\ud68c\uc9c0<\/div>\n<\/div>\n<div class=\"buttons text-s\">\n<p>&nbsp;<\/p>\n<\/div>\n<\/li>\n<li class=\"ListArticleItem u-margin-l-bottom\">\n<div class=\"sub-heading u-margin-xs-bottom\">\n<p id=\"citing-articles-article-2-title\" class=\"u-font-serif\"><a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.21203\/rs.3.rs-3691555\/v1\" target=\"_blank\" rel=\"noopener\"><span class=\"anchor-text\">\ud5c8\ud608\ub1cc\uc878\uc911\uc5d0\uc11c \ud30c\uc774\ub86d\ud1a0\uc2dc\uc2a4 \uad00\ub828 \ucc28\ubcc4\uc801\uc73c\ub85c \ubc1c\ud604\ub418\ub294 \uc720\uc804\uc790\uc758 \uc720\uc804\uc790 \ubc1c\ud604 \ud504\ub85c\ud30c\uc77c\uc5d0 \ub300\ud55c \uae30\uacc4 \ud559\uc2b5 \ubd84\uc11d\uc744 \ud1b5\ud574 \uc57d\ubb3c \uc6a9\ub3c4 \ubcc0\uacbd\uc744 \uc704\ud55c \uc7a0\uc7ac\uc801\uc778 \ud45c\uc801\uc774 \ubc1d\ud600\uc84c\uc2b5\ub2c8\ub2e4<\/span><\/a><\/p>\n<div class=\"text-s\">2023, \ub9ac\uc11c\uce58\uc2a4\ud018\uc5b4<\/div>\n<\/div>\n<div class=\"buttons text-s\"><\/div>\n<\/li>\n<li class=\"ListArticleItem u-margin-l-bottom\">\n<div class=\"sub-heading u-margin-xs-bottom\">\n<p id=\"citing-articles-article-3-title\" class=\"u-font-serif\"><a class=\"anchor anchor-default\" href=\"https:\/\/doi.org\/10.1002\/ptr.7994\" target=\"_blank\" rel=\"noopener\"><span class=\"anchor-text\">PI3K\/Akt \uc2e0\ud638 \uc804\ub2ec\uc744 \ud45c\uc801\uc73c\ub85c \ud558\ub294 \ud5c8\ud608\uc131 \ub1cc\uc878\uc911\uc5d0 \ub300\ud55c \uc2dd\ubb3c\uc694\ubc95\uc758 \ubc1c\uc804<\/span><\/a><\/p>\n<div class=\"text-s\">2023\ub144, \uc2dd\ubb3c\uce58\ub8cc\uc5f0\uad6c<\/div>\n<\/div>\n<div class=\"buttons text-s\"><\/div>\n<\/li>\n<\/ul>\n<\/div>\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222013889\">\uc6d0\ucc9c<\/a><\/p>\n<\/div>\n<\/section>\n<\/div>\n<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>This suggests that breviscapine may significantly improve the cognitive function of CCI rats and reduce the pathological damage of ischemic neurons, and its mechanism may be related to the inhibition of NLRP3 inflammasome activation and pyroptosis pathway in brain tissue [211].<\/p>","protected":false},"author":1,"featured_media":5371,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[9],"tags":[],"class_list":["post-5171","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-supplements"],"_links":{"self":[{"href":"https:\/\/directcm.com\/ko\/wp-json\/wp\/v2\/posts\/5171","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/directcm.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/directcm.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/directcm.com\/ko\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/directcm.com\/ko\/wp-json\/wp\/v2\/comments?post=5171"}],"version-history":[{"count":1,"href":"https:\/\/directcm.com\/ko\/wp-json\/wp\/v2\/posts\/5171\/revisions"}],"predecessor-version":[{"id":5392,"href":"https:\/\/directcm.com\/ko\/wp-json\/wp\/v2\/posts\/5171\/revisions\/5392"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/directcm.com\/ko\/wp-json\/wp\/v2\/media\/5371"}],"wp:attachment":[{"href":"https:\/\/directcm.com\/ko\/wp-json\/wp\/v2\/media?parent=5171"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/directcm.com\/ko\/wp-json\/wp\/v2\/categories?post=5171"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/directcm.com\/ko\/wp-json\/wp\/v2\/tags?post=5171"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}