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This study explores the influence of extraction solvents on the composition and bioactivity of Salvia fruticosa extracts. Ultrasound-assisted extraction with water, ethanol and their mixtures in variable proportions was used to produce four different extracts.

Ultra-endurance events, which are greater than 6 h in duration1 have gained substantial popularity and global participation2,3. Ultramarathon runs on trails are the most popular ultra-endurance events4, and the recent increase in these events implies an increase in both competitive and recreational participants2,3.